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3,4,8-trimethylimidazo(4,5-f)quinoxalin-2-amine and 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine

3,4,8-trimethylimidazo(4,5-f)quinoxalin-2-amine has been researched along with 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine in 34 studies

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.94)18.7374
1990's13 (38.24)18.2507
2000's11 (32.35)29.6817
2010's9 (26.47)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Liu, ZC; Nagao, M; Sugimura, T; Wakabayashi, K; Zhang, XM1
Diachenko, GW; Hargraves, WA; Jackson, LS; Stroup, WH1
Dragsted, LO; Frandsen, H; Grivas, S; Larsen, JC1
Brown, ED; Cunningham, PL; Felton, JS; Knize, MG; Levander, OA; Rothman, N; Salmon, CP; Sinha, R1
Carroll, KL; Dolbeare, FA; Felton, JS; Knize, MG; Moore, DH1
Jägerstad, M; Johansson, MA1
Latva-Kala, KJ; Sauri, TM; Tikkanen, LM1
Fay, LB; Gross, GA; Skipper, PL; Stillwell, WG; Tannenbaum, SR; Turesky, RJ1
Gooderham, MJ; Knize, MG; Lynch, AM; Murray, S1
Gustafsson, JA; Möller, L; Wohlin, P; Zeisig, M1
Felton, JS; Hopmans, EC; Knize, MG; Salmon, CP1
Felton, JS; Knize, MG; Mehta, SS; Salmon, CP1
Frandsen, H1
Cole, KJ; Grover, PL; Marquardt, H; Martin, FL; Pfau, W; Phillips, DH; Venitt, S1
Futakuchi, M; Hirose, M; Kimoto, N; Kono, T; Lin, C; Nishibe, S; Shirai, T; Yamaguchi, T1
Alavanja, MC; Brownson, RC; Curtin, J; Kulldorff, M; Sinha, R; Swanson, CA1
Amantana, A; Dashwood, RH; Orner, GA; Provost, C; Santana-Rios, G; Wu, SY1
Persson, E; Sjöholm, I; Skog, K1
Andriole, GL; Cross, AJ; Hayes, RB; Kirsh, VA; Peters, U; Reding, D; Sinha, R1
Busquets, R; Galceran, MT; Puignou, L; Toribio, F1
Peterson, S; Turesky, RJ; Wang, R; Yu, MC; Yuan, JM1
Chen, F; Cheng, KW; Peng, X; Simon, JE; Wang, M; Wu, Q; Zheng, ZP1
Knasmüller, S; Koller, V; Sontag, G; Stidl, R1
Gibis, M; Jautz, U; Morlock, GE1
Bagnardi, V; Bertazzi, PA; Caporaso, NE; Consonni, D; Cross, AJ; Lam, TK; Landi, MT; Randi, G; Sinha, R; Subar, AF1
Peng, Z; Shao, B; Wan, K; Wu, G; Yang, H; Yao, Y1
Ding, Z; Guo, D; Li, F; Su, M; Wang, M; Yao, J1
Cross, AJ; Harper, G; Hartman, TJ; Laio, J; Lazarus, P; Lesko, SM; Miller, PE; Muscat, JE; Sinha, R; Zhu, J1
Filipič, M; Pezdirc, M; Žegura, B1
Mei, J; Wang, S; Yu, C; Zhang, Y1
Cooper, KM; Cuskelly, G; Jankhaikhot, N1
Artioli, GG; Carpentier, A; Dantas, WS; Dörr, FA; Fernandes, AL; Gualano, B; Murai, IH; Pereira, RT; Pinto, E; Poortmans, JR; Roschel, H; Santinho, MA; Seguro, AC; Solis, MY1
Giovannucci, EL; Nimptsch, K; Platz, EA; Rohrmann, S; Sinha, R; Willett, WC; Wu, K1
Gibis, M; Weiss, J1

Trials

2 trial(s) available for 3,4,8-trimethylimidazo(4,5-f)quinoxalin-2-amine and 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine

ArticleYear
A prospective study of meat and meat mutagens and prostate cancer risk.
    Cancer research, 2005, Dec-15, Volume: 65, Issue:24

    Topics: Aged; Benzo(a)pyrene; Cooking; Diet; Humans; Imidazoles; Male; Meat; Middle Aged; Mutagens; Prospective Studies; Prostatic Neoplasms; Quinoxalines; Risk Factors; Surveys and Questionnaires

2005
Can creatine supplementation form carcinogenic heterocyclic amines in humans?
    The Journal of physiology, 2015, Sep-01, Volume: 593, Issue:17

    Topics: Adult; Amines; Carcinogens; Creatine; Cross-Over Studies; Diet; Female; Furans; Humans; Imidazoles; Male; Quinoxalines; Single-Blind Method

2015

Other Studies

32 other study(ies) available for 3,4,8-trimethylimidazo(4,5-f)quinoxalin-2-amine and 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine

ArticleYear
Mutagenic and carcinogenic heterocyclic amines in Chinese cooked foods.
    Mutation research, 1988, Volume: 201, Issue:1

    Topics: China; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Cooking; Diet; Food Analysis; Heterocyclic Compounds; Imidazoles; Mutagenicity Tests; Mutagens; Mutation; Neoplasms; Quinolines; Quinoxalines

1988
Heterocyclic aromatic amine content of selected beef flavors.
    Mutation research, 1994, Volume: 320, Issue:1-2

    Topics: Animals; Cattle; Chromatography, High Pressure Liquid; Creatine; Creatinine; Dose-Response Relationship, Drug; Flavoring Agents; Imidazoles; Linear Models; Meat Products; Mutagenicity Tests; Mutagens; Quinolines; Quinoxalines; Salmonella typhimurium

1994
Antibodies to the food mutagens, 2-amino-1-methyl-6-phenylimidazo [4,5-b]pyridine and 2-amino-3,4,8-trimethylimidazo[4,5-f]quinoxaline: useful for immunoassay and immunoaffinity chromatography of biological samples.
    Carcinogenesis, 1995, Volume: 16, Issue:11

    Topics: Animals; Antibodies, Monoclonal; Carcinogens; Chromatography, Affinity; Chromatography, High Pressure Liquid; Enzyme-Linked Immunosorbent Assay; Female; Imidazoles; Male; Mice; Mutagens; Quinoxalines; Rats; Rats, Wistar

1995
Heterocyclic amine content in fast-food meat products.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1995, Volume: 33, Issue:7

    Topics: Amines; Carcinogens; Chromatography, High Pressure Liquid; Food Analysis; Food Contamination; Heterocyclic Compounds; Imidazoles; Maryland; Meat Products; Mutagenicity Tests; Mutagens; Quinoxalines; Reference Standards

1995
Effect of cooking time and temperature on the heterocyclic amine content of fried beef patties.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1994, Volume: 32, Issue:7

    Topics: Animals; Cattle; Cooking; Hot Temperature; Imidazoles; Meat; Mutagens; Quinolines; Quinoxalines; Time Factors

1994
Occurrence of mutagenic/carcinogenic heterocyclic amines in meat and fish products, including pan residues, prepared under domestic conditions.
    Carcinogenesis, 1994, Volume: 15, Issue:8

    Topics: Antioxidants; Carcinogens; Cooking; Fish Products; Imidazoles; Meat Products; Mutagens; Quinolines; Quinoxalines

1994
Screening of heat-processed Finnish foods for the mutagens 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline, 2-amino-3,4,8-trimethylimidazo[4,5-f]quinoxaline and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1993, Volume: 31, Issue:10

    Topics: Animals; Cooking; Finland; Food Analysis; Food-Processing Industry; Gas Chromatography-Mass Spectrometry; Hot Temperature; Imidazoles; Male; Mutagenicity Tests; Mutagens; Quinoxalines; Rats; Rats, Wistar; Salmonella typhimurium

1993
Heterocyclic aromatic amine formation in grilled bacon, beef and fish and in grill scrapings.
    Carcinogenesis, 1993, Volume: 14, Issue:11

    Topics: Animals; Carbolines; Carcinogens; Cattle; Cooking; Fishes; Hot Temperature; Imidazoles; Meat; Quinoxalines; Swine; Time Factors

1993
Quantification of the carcinogens 2-amino-3,8-dimethyl- and 2-amino-3,4,8-trimethylimidazo[4,5-f]quinoxaline and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in food using a combined assay based on gas chromatography-negative ion mass spectrometry.
    Journal of chromatography, 1993, Jul-02, Volume: 616, Issue:2

    Topics: Animals; Carcinogens; Cattle; Chickens; Gas Chromatography-Mass Spectrometry; Imidazoles; Isotope Labeling; Meat; Meat Products; Mutagens; Quinoxalines; Reference Standards; Swine

1993
32-P-HPLC analysis of DNA adducts formed in vitro and in vivo by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and 2-amino-3,4,8-trimethyl-3H-imidazo[4,5-f]quinoxaline, utilizing an improved adduct enrichment procedure.
    Chemical research in toxicology, 1996, Volume: 9, Issue:6

    Topics: Animals; Butanols; Carcinogens; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; DNA Adducts; Imidazoles; Isotope Labeling; Male; Mutagens; Phosphorus Radioisotopes; Quinoxalines; Rats; Rats, Wistar

1996
Analysis of foods for heterocyclic aromatic amine carcinogens by solid-phase extraction and high-performance liquid chromatography.
    Journal of chromatography. A, 1997, Feb-28, Volume: 763, Issue:1-2

    Topics: Amines; Animals; Carcinogens; Chromatography, High Pressure Liquid; Food Analysis; Heterocyclic Compounds; Imidazoles; Meat; Quinolines; Quinoxalines; Spectrophotometry, Ultraviolet

1997
Analysis of cooked muscle meats for heterocyclic aromatic amine carcinogens.
    Mutation research, 1997, May-12, Volume: 376, Issue:1-2

    Topics: Animals; Cattle; Chickens; Chromatography, High Pressure Liquid; Cooking; Food Analysis; Imidazoles; Meat; Mutagenicity Tests; Mutagens; Quinoxalines; Salmonella typhimurium

1997
Excretion of DNA adducts of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and 2-amino-3,4,8-trimethylimidazo[4,5-f]quinoxaline, PhIP-dG, PhIP-DNA and DiMeIQx-DNA from the rat.
    Carcinogenesis, 1997, Volume: 18, Issue:8

    Topics: Animals; Biomarkers; Carcinogens; Chromatography, High Pressure Liquid; Deoxyguanosine; DNA Adducts; Feces; Imidazoles; Male; Quinoxalines; Rats; Rats, Wistar; Time Factors

1997
Heterocyclic aromatic amines induce DNA strand breaks and cell transformation.
    Carcinogenesis, 1999, Volume: 20, Issue:4

    Topics: Animals; Biotransformation; Carbolines; Carcinogens, Environmental; Cell Transformation, Neoplastic; Cytochrome P-450 Enzyme System; DNA Damage; Dose-Response Relationship, Drug; Fibroblasts; Food; Hot Temperature; Humans; Imidazoles; Lymphocytes; Male; Mice; Mice, Inbred C3H; Micronucleus Tests; Microsomes, Liver; Mutagenicity Tests; Mutagens; Quinolines; Quinoxalines; Rats; Salmonella typhimurium; Structure-Activity Relationship

1999
Effects of arctiin on PhIP-induced mammary, colon and pancreatic carcinogenesis in female Sprague-Dawley rats and MeIQx-induced hepatocarcinogenesis in male F344 rats.
    Cancer letters, 2000, Jul-03, Volume: 155, Issue:1

    Topics: Animals; Biological Assay; Body Weight; Carcinogens; Carcinoma; Colonic Neoplasms; Diet; Drugs, Chinese Herbal; Female; Fibroadenoma; Furans; Glucosides; Glutathione Transferase; Imidazoles; Liver; Male; Mammary Neoplasms, Experimental; Pancreatic Neoplasms; Quinoxalines; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Time Factors

2000
Dietary heterocyclic amines and the risk of lung cancer among Missouri women.
    Cancer research, 2000, Jul-15, Volume: 60, Issue:14

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Case-Control Studies; Diet; Female; Heterocyclic Compounds; Hot Temperature; Humans; Imidazoles; Lung Neoplasms; Middle Aged; Missouri; Multivariate Analysis; Quinoxalines; Risk Factors; Smoking

2000
Potent antimutagenic activity of white tea in comparison with green tea in the Salmonella assay.
    Mutation research, 2001, Aug-22, Volume: 495, Issue:1-2

    Topics: Animals; Antimutagenic Agents; Catechin; Chromatography, High Pressure Liquid; Cooking; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Drug Interactions; Imidazoles; Microsomes, Liver; Mutagenicity Tests; Mutagens; Oxidoreductases; Quinolines; Quinoxalines; Rats; Salmonella typhimurium; Tea

2001
Effect of high water-holding capacity on the formation of heterocyclic amines in fried beefburgers.
    Journal of agricultural and food chemistry, 2003, Jul-16, Volume: 51, Issue:15

    Topics: Animals; Carcinogens; Cattle; Heterocyclic Compounds; Hot Temperature; Imidazoles; Meat; Quinoxalines; Water

2003
Heterocyclic amines in griddled beef steak analysed using a single extract clean-up procedure.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2007, Volume: 45, Issue:4

    Topics: Amines; Animals; Cattle; Cooking; Heterocyclic Compounds; Imidazoles; Meat; Mutagens; Quinoxalines

2007
Tobacco smoking and urinary levels of 2-amino-9H-pyrido[2,3-b]indole in men of Shanghai, China.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2007, Volume: 16, Issue:8

    Topics: Animals; Carbolines; Carcinogens; Case-Control Studies; Chickens; China; Cohort Studies; Creatinine; Follow-Up Studies; Humans; Imidazoles; Male; Meat; Middle Aged; Population Surveillance; Prospective Studies; Quinoxalines; Smoking; Swine

2007
Inhibitory effect of fruit extracts on the formation of heterocyclic amines.
    Journal of agricultural and food chemistry, 2007, Dec-12, Volume: 55, Issue:25

    Topics: Ananas; Animals; Cattle; Fruit; Heterocyclic Compounds; Hot Temperature; Imidazoles; Malus; Meat; Plant Extracts; Proanthocyanidins; Quinoxalines; Sambucus; Seeds; Vitis

2007
Binding of heterocyclic aromatic amines by lactic acid bacteria: results of a comprehensive screening trial.
    Molecular nutrition & food research, 2008, Volume: 52, Issue:3

    Topics: Anticarcinogenic Agents; Antimutagenic Agents; Carbolines; Carcinogens; Food Handling; Heterocyclic Compounds; Hot Temperature; Imidazoles; Lactobacillus; Meat; Mutagenicity Tests; Mutagens; Quinolines; Quinoxalines

2008
Quantification of heterocyclic aromatic amines in fried meat by HPTLC/UV-FLD and HPLC/UV-FLD: a comparison of two methods.
    Journal of agricultural and food chemistry, 2008, Jun-25, Volume: 56, Issue:12

    Topics: Amines; Animals; Carbolines; Carcinogens; Cattle; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Harmine; Heterocyclic Compounds; Hot Temperature; Imidazoles; Meat; Mutagens; Quinoxalines

2008
Intakes of red meat, processed meat, and meat mutagens increase lung cancer risk.
    Cancer research, 2009, Feb-01, Volume: 69, Issue:3

    Topics: Aged; Animals; Case-Control Studies; Cattle; Chickens; Female; Humans; Imidazoles; Italy; Lung Neoplasms; Male; Meat; Meat Products; Middle Aged; Mutagens; Quinoxalines

2009
[Simultaneous determination of 9 heterocyclic aromatic amine in poultry products by solid-phase extraction-high performance liquid chromatography].
    Se pu = Chinese journal of chromatography, 2011, Volume: 29, Issue:8

    Topics: Amines; Animals; Carcinogens; Chromatography, High Pressure Liquid; Food Analysis; Food Contamination; Heterocyclic Compounds; Imidazoles; Poultry Products; Quinoxalines; Solid Phase Extraction

2011
[Determination of 14 heterocyclic aromatic amines in wine by liquid chromatography-ion trap-time of flight tandem mass spectrometry].
    Se pu = Chinese journal of chromatography, 2012, Volume: 30, Issue:7

    Topics: Amines; Chromatography, Liquid; Food Contamination; Heterocyclic Compounds; Imidazoles; Quinoxalines; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Wine

2012
Meat-related compounds and colorectal cancer risk by anatomical subsite.
    Nutrition and cancer, 2013, Volume: 65, Issue:2

    Topics: Aged; Animals; Benzo(a)pyrene; Case-Control Studies; Colonic Neoplasms; Colorectal Neoplasms; Cooking; Feeding Behavior; Female; Humans; Imidazoles; Logistic Models; Male; Meat; Meat Products; Middle Aged; Nitrates; Nitrites; Pennsylvania; Poultry; Quinoxalines; Rectal Neoplasms; Risk Factors; Surveys and Questionnaires

2013
Genotoxicity and induction of DNA damage responsive genes by food-borne heterocyclic aromatic amines in human hepatoma HepG2 cells.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2013, Volume: 59

    Topics: Biotransformation; Carcinogens; Cell Cycle; Cell Survival; DNA Breaks; DNA Damage; Food Contamination; Gene Expression Regulation; Hep G2 Cells; Hepatocytes; Hot Temperature; Humans; Imidazoles; Mutagens; Quinolines; Quinoxalines

2013
Formation and mitigation of heterocyclic aromatic amines in fried pork.
    Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 2013, Volume: 30, Issue:9

    Topics: Animals; Antioxidants; Carcinogens; China; Cooking; Fast Foods; Food Contamination; Food Preservatives; Heterocyclic Compounds; Imidazoles; Meat; Meat Products; Mutagens; Plant Extracts; Plant Leaves; Polycyclic Aromatic Hydrocarbons; Quinoxalines; Sasa; Sus scrofa

2013
Optimised extraction of heterocyclic aromatic amines from blood using hollow fibre membrane liquid-phase microextraction and triple quadrupole mass spectrometry.
    Journal of chromatography. A, 2014, Sep-05, Volume: 1358

    Topics: Animals; Biomarkers; Carcinogens; Chromatography, High Pressure Liquid; Cooking; Humans; Hydrogen-Ion Concentration; Imidazoles; Liquid Phase Microextraction; Meat; Mutagens; Polypropylenes; Quinoxalines; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry

2014
Intake of Meat Mutagens and Risk of Prostate Cancer in a Cohort of U.S. Health Professionals.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2015, Volume: 24, Issue:10

    Topics: Adult; Aged; Benzimidazoles; Cooking; Feeding Behavior; Follow-Up Studies; Health Personnel; Humans; Imidazoles; Incidence; Male; Meat; Middle Aged; Mutagens; Prostatic Neoplasms; Quinoxalines; Reproducibility of Results; Retrospective Studies; Risk Assessment; Risk Factors; Surveys and Questionnaires; United States

2015
Impact of Precursors Creatine, Creatinine, and Glucose on the Formation of Heterocyclic Aromatic Amines in Grilled Patties of Various Animal Species.
    Journal of food science, 2015, Volume: 80, Issue:11

    Topics: Acids, Heterocyclic; Amines; Amino Acids; Animals; Cattle; Chromatography, High Pressure Liquid; Cooking; Creatine; Creatinine; Glucose; Horses; Hot Temperature; Humans; Imidazoles; Meat; Mutagens; Poultry; Pyridines; Quinoxalines; Sheep; Swine

2015