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3,3',5'-triiodothyronine and thyroxine

3,3',5'-triiodothyronine has been researched along with thyroxine in 6 studies

*Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism. [MeSH]

*Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism. [MeSH]

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19903 (50.00)18.7374
1990's1 (16.67)18.2507
2000's1 (16.67)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bolger, MB; Dietrich, SW; Jorgensen, EC; Kollman, PA1
Blake, CC; McKinney, JD; Oatley, SJ; Rickenbacher, U1
Mariash, CN; Oppenheimer, JH; Schueler, PA; Schwartz, HL; Strait, KA1
Chae, K; Fannin, R; Jordan, S; McKinney, J; Pedersen, L; Rickenbacher, U1
Abdalla, A; Friesema, EC; Ganguly, S; Halestrap, AP; Manning Fox, JE; Visser, TJ1
Ecker, GF; Holy, M; Jurik, A; Sitte, HH; Stockner, T; Zdrazil, B1

Reviews

1 review(s) available for 3,3',5'-triiodothyronine and thyroxine

ArticleYear
Thyroxine analogues. 23. Quantitative structure-activity correlation studies of in vivo and in vitro thyromimetic activities.
    Journal of medicinal chemistry, 1977, Volume: 20, Issue:7

    Topics: Animals; Cell Nucleus; Goiter; In Vitro Techniques; Liver; Mathematics; Molecular Conformation; Protein Binding; Rats; Receptors, Cell Surface; Structure-Activity Relationship; Thyroxine; Thyroxine-Binding Proteins

1977

Other Studies

5 other study(ies) available for 3,3',5'-triiodothyronine and thyroxine

ArticleYear
Structurally specific binding of halogenated biphenyls to thyroxine transport protein.
    Journal of medicinal chemistry, 1986, Volume: 29, Issue:5

    Topics: Binding Sites; Binding, Competitive; Halogens; Humans; Hydroxylation; Kinetics; Models, Molecular; Polychlorinated Biphenyls; Polychlorinated Dibenzodioxins; Prealbumin; Receptors, Cell Surface; Receptors, Thyroid Hormone; Structure-Activity Relationship; Thyroxine-Binding Proteins

1986
Binding of 3,5,3'-triiodothyronine (T3) and its analogs to the in vitro translational products of c-erbA protooncogenes: differences in the affinity of the alpha- and beta-forms for the acetic acid analog and failure of the human testis and kidney alpha-2
    Molecular endocrinology (Baltimore, Md.), 1990, Volume: 4, Issue:2

    Topics: Amino Acid Sequence; Animals; DNA; DNA Probes; Electrophoresis, Polyacrylamide Gel; Genomic Library; Humans; Kidney; Male; Molecular Sequence Data; Protein Biosynthesis; Proto-Oncogene Proteins; Receptors, Thyroid Hormone; Testis; Triiodothyronine

1990
Polychlorinated biphenyls and related compound interactions with specific binding sites for thyroxine in rat liver nuclear extracts.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:1

    Topics: Animals; Binding, Competitive; Cell Nucleus; Kinetics; Liver; Polychlorinated Biphenyls; Polychlorinated Dibenzodioxins; Rats; Receptors, Thyroid Hormone; Structure-Activity Relationship; Thyroxine

1987
Identification of monocarboxylate transporter 8 as a specific thyroid hormone transporter.
    The Journal of biological chemistry, 2003, Oct-10, Volume: 278, Issue:41

    Topics: Amino Acid Sequence; Animals; Base Sequence; Biological Transport, Active; Cloning, Molecular; DNA; Female; In Vitro Techniques; Kinetics; Male; Molecular Sequence Data; Monocarboxylic Acid Transporters; Oocytes; Rats; Recombinant Proteins; Sequence Homology, Amino Acid; Thyroid Hormones; Tissue Distribution; Xenopus laevis

2003
A binding mode hypothesis of tiagabine confirms liothyronine effect on γ-aminobutyric acid transporter 1 (GAT1).
    Journal of medicinal chemistry, 2015, Mar-12, Volume: 58, Issue:5

    Topics: Computer Simulation; GABA Agonists; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; HEK293 Cells; High-Throughput Screening Assays; Humans; Models, Molecular; Molecular Docking Simulation; Molecular Structure; Nipecotic Acids; Structure-Activity Relationship; Tiagabine; Triiodothyronine

2015