3,3',4'-trihydroxyflavone has been researched along with fisetin in 6 studies
| Studies (3,3',4'-trihydroxyflavone) | Trials (3,3',4'-trihydroxyflavone) | Recent Studies (post-2010) (3,3',4'-trihydroxyflavone) | Studies (fisetin) | Trials (fisetin) | Recent Studies (post-2010) (fisetin) |
|---|---|---|---|---|---|
| 39 | 0 | 22 | 667 | 4 | 507 |
| Protein | Taxonomy | 3,3',4'-trihydroxyflavone (IC50) | fisetin (IC50) |
|---|---|---|---|
| Chain B, Cell division protein kinase 6 | Homo sapiens (human) | 0.85 | |
| G2/mitotic-specific cyclin-B2 | Homo sapiens (human) | 0.79 | |
| Cyclin-dependent kinase 1 | Homo sapiens (human) | 0.79 | |
| Serine/threonine-protein kinase pim-1 | Homo sapiens (human) | 0.85 | |
| Pyruvate kinase PKM | Homo sapiens (human) | 0.9 | |
| G2/mitotic-specific cyclin-B1 | Homo sapiens (human) | 0.79 | |
| G2/mitotic-specific cyclin-B | Marthasterias glacialis (spiny starfish) | 0.6575 | |
| Polyunsaturated fatty acid lipoxygenase ALOX15 | Homo sapiens (human) | 1.4 | |
| Polyunsaturated fatty acid lipoxygenase ALOX12 | Homo sapiens (human) | 0.95 | |
| Glycogen synthase kinase-3 beta | Rattus norvegicus (Norway rat) | 0.6575 | |
| Casein kinase II subunit alpha' | Homo sapiens (human) | 0.5667 | |
| Cyclin-dependent kinase 2 | Homo sapiens (human) | 5 | |
| 1-deoxy-D-xylulose 5-phosphate reductoisomerase | Escherichia coli K-12 | 3.5 | |
| Xanthine dehydrogenase/oxidase | Homo sapiens (human) | 4.33 | |
| Glycogen synthase kinase-3 alpha | Homo sapiens (human) | 0.42 | |
| Glycogen synthase kinase-3 beta | Homo sapiens (human) | 0.42 | |
| Mitogen-activated protein kinase 10 | Homo sapiens (human) | 2.65 | |
| Casein kinase II subunit beta | Homo sapiens (human) | 0.5667 | |
| Casein kinase II subunit alpha | Homo sapiens (human) | 0.5667 | |
| Cyclin-dependent kinase 6 | Homo sapiens (human) | 0.696 | |
| Cyclin-dependent-like kinase 5 | Homo sapiens (human) | 0.64 | |
| Cyclin homolog | Herpesvirus saimiri (strain 11) | 0.6575 | |
| Cyclin-dependent kinase 5 activator 1 | Homo sapiens (human) | 0.64 | |
| Mitogen-activated protein kinase 14 | Homo sapiens (human) | 2.65 | |
| Integrase | Human immunodeficiency virus 1 | 8.5 | |
| Casein kinase II subunit alpha 3 | Homo sapiens (human) | 0.35 | |
| G2/mitotic-specific cyclin-B3 | Homo sapiens (human) | 0.79 | |
| Enoyl-acyl-carrier protein reductase | Plasmodium falciparum (malaria parasite P. falciparum) | 1 | |
| 3-oxoacyl-acyl-carrier protein reductase | Plasmodium falciparum (malaria parasite P. falciparum) | 4.1 | |
| Beta-hydroxyacyl-ACP dehydratase precursor (Fatty acid synthesis protein) | Plasmodium falciparum (malaria parasite P. falciparum) | 2 | |
| Aurora kinase B | Homo sapiens (human) | 2.63 | |
| Cyclin-dependent kinase 1 | Oryzias latipes (Japanese medaka) | 0.6575 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (66.67) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bast, A; Haenen, GR; Hageman, JA; Menge, WM; van Acker, FA; van Der Vijgh, WJ | 1 |
| Domina, NG; Khlebnikov, AI; Kirpotina, LN; Quinn, MT; Schepetkin, IA | 1 |
| Hong, C; Jeong, S; Kim, KH; Lee, J; Park, T | 1 |
| Eom, S; Hwang, DS; Hyun, J; Jo, G; Lee, Y; Lim, Y; Park, JC; Woo, Y | 1 |
| Chiruta, C; Dargusch, R; Maher, P; Schubert, D | 1 |
| Chan, EC; Pannangpetch, P; Woodman, OL | 1 |
6 other study(ies) available for 3,3',4'-trihydroxyflavone and fisetin
| Article | Year |
|---|---|
Synthesis of novel 3,7-substituted-2-(3',4'-dihydroxyphenyl)flavones with improved antioxidant activity.
Topics: Animals; Antioxidants; Flavonoids; Free Radical Scavengers; In Vitro Techniques; Lipid Peroxidation; Male; Microsomes, Liver; Rats; Rats, Wistar | 2000 |
Improved quantitative structure-activity relationship models to predict antioxidant activity of flavonoids in chemical, enzymatic, and cellular systems.
Topics: Animals; Antioxidants; Drug Design; Flavonoids; Humans; Phagocytes; Phenols; Polyphenols; Quantitative Structure-Activity Relationship | 2007 |
3-Hydroxychromones as cyclin-dependent kinase inhibitors: synthesis and biological evaluation.
Topics: Antineoplastic Agents; Binding Sites; Cell Line, Tumor; Cell Survival; Chromones; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor Proteins; Humans; Inhibitory Concentration 50; Protein Binding; Structure-Activity Relationship | 2007 |
Relationships between structures of hydroxyflavones and their antioxidative effects.
Topics: Antioxidants; Flavones; Flavonoids; Flavonols; Free Radical Scavengers; Models, Molecular; Quantitative Structure-Activity Relationship | 2010 |
Chemical modification of the multitarget neuroprotective compound fisetin.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Cell Line; Cell Survival; Chalcones; Flavonoids; Flavonols; Glutathione; Humans; Mice; Microglia; Neuroprotective Agents; NF-E2-Related Factor 2; Oxidative Stress; Quinolines; Rats; Structure-Activity Relationship | 2012 |
Relaxation to flavones and flavonols in rat isolated thoracic aorta: mechanism of action and structure-activity relationships.
Topics: Animals; Aorta, Thoracic; Apigenin; Calcium; Dose-Response Relationship, Drug; Drug Interactions; Endothelium, Vascular; Flavonoids; Flavonols; In Vitro Techniques; Luteolin; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nifedipine; Phenylephrine; Quercetin; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship | 2000 |