Compounds > 3'-o-methyl-nordihydroguaiaretic acid
Page last updated: 2024-09-03

3'-o-methyl-nordihydroguaiaretic acid and masoprocol

3'-o-methyl-nordihydroguaiaretic acid has been researched along with masoprocol in 5 studies

Compound Research Comparison

Studies
(3'-o-methyl-nordihydroguaiaretic acid)		Trials
(3'-o-methyl-nordihydroguaiaretic acid)		Recent Studies (post-2010)
(3'-o-methyl-nordihydroguaiaretic acid)		Studies
(masoprocol)		Trials
(masoprocol)		Recent Studies (post-2010) (masoprocol)
7011,5278163

Protein Interaction Comparison

ProteinTaxonomy3'-o-methyl-nordihydroguaiaretic acid (IC50)masoprocol (IC50)
Prostaglandin G/H synthase 1Ovis aries (sheep)3.5
Seed linoleate 13S-lipoxygenase-1Glycine max (soybean)3.5
Prostaglandin G/H synthase 2Homo sapiens (human)3.5

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's2 (40.00)18.2507
2000's2 (40.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Schegg, KM; Welch, W1
Bates, RB; Brady, JN; Clanton, DJ; Dittmer, J; Gnabre, JN; Huang, RC; Ito, Y1
Giza, P; Gnabre, J; Huang, RC; Hwu, JR; Tseng, WN1
Callahan, M; Craigo, J; DeLucia, AL; Huang, RC1
Allen, KL; Awad, KS; DeLucia, AL; Lynch, WP; Tschantz, DR1

Other Studies

5 other study(ies) available for 3'-o-methyl-nordihydroguaiaretic acid and masoprocol

ArticleYear
The effect of nordihydroguaiaretic acid and related lignans on formyltetrahydrofolate synthetase and carboxylesterase.
    Biochimica et biophysica acta, 1984, Jul-31, Volume: 788, Issue:2

    Topics: Animals; Antineoplastic Agents; Carboxylic Ester Hydrolases; Catechols; Cattle; Cells, Cultured; Cytoplasm; Formate-Tetrahydrofolate Ligase; Guinea Pigs; Humans; Kinetics; Ligases; Lignans; Macromolecular Substances; Masoprocol; Mice; Microsomes; Naphthols; Plant Extracts; Protein Binding; Rats

1984
Inhibition of human immunodeficiency virus type 1 transcription and replication by DNA sequence-selective plant lignans.
    Proceedings of the National Academy of Sciences of the United States of America, 1995, Nov-21, Volume: 92, Issue:24

    Topics: Animals; Antiviral Agents; Base Sequence; Chlorocebus aethiops; DNA Primers; DNA Replication; Gene Expression Regulation, Viral; Gene Products, tat; HIV Core Protein p24; HIV Long Terminal Repeat; HIV-1; Humans; Lignans; Masoprocol; Molecular Sequence Data; NF-kappa B; RNA, Messenger; Sp1 Transcription Factor; tat Gene Products, Human Immunodeficiency Virus; Transcription, Genetic; Transcriptional Activation; Virus Replication

1995
Antiviral activities of methylated nordihydroguaiaretic acids. 1. Synthesis, structure identification, and inhibition of tat-regulated HIV transactivation.
    Journal of medicinal chemistry, 1998, Jul-30, Volume: 41, Issue:16

    Topics: Alkaline Phosphatase; Animals; Anti-HIV Agents; COS Cells; DNA, Viral; Enzyme Inhibitors; Epithelial Cells; Gene Products, tat; HIV; Humans; Masoprocol; Mice; Plasmids; tat Gene Products, Human Immunodeficiency Virus; Transcriptional Activation

1998
Inhibition of human papillomavirus type 16 gene expression by nordihydroguaiaretic acid plant lignan derivatives.
    Antiviral research, 2000, Volume: 47, Issue:1

    Topics: Antiviral Agents; Female; Gene Expression Regulation, Viral; HIV Long Terminal Repeat; Humans; Lignans; Masoprocol; Papillomaviridae; Promoter Regions, Genetic; Simian virus 40; Tumor Cells, Cultured

2000
A plant lignan, 3'-O-methyl-nordihydroguaiaretic acid, suppresses papillomavirus E6 protein function, stabilizes p53 protein, and induces apoptosis in cervical tumor cells.
    Molecular carcinogenesis, 2007, Volume: 46, Issue:7

    Topics: Apoptosis; Apoptosis Regulatory Proteins; bcl-2-Associated X Protein; Caspase 3; Caspase 9; Enzyme Activation; Female; Humans; Luciferases; Masoprocol; Oncogene Proteins, Viral; Plants; Proto-Oncogene Proteins; Repressor Proteins; Transcription, Genetic; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Uterine Cervical Neoplasms

2007