Compounds > 3'-fluorothymidine-5'-triphosphate
Page last updated: 2024-09-04

3'-fluorothymidine-5'-triphosphate and zidovudine

3'-fluorothymidine-5'-triphosphate has been researched along with zidovudine in 4 studies

Compound Research Comparison

Studies
(3'-fluorothymidine-5'-triphosphate)		Trials
(3'-fluorothymidine-5'-triphosphate)		Recent Studies (post-2010)
(3'-fluorothymidine-5'-triphosphate)		Studies
(zidovudine)		Trials
(zidovudine)		Recent Studies (post-2010) (zidovudine)
70110,1801,3991,188

Protein Interaction Comparison

ProteinTaxonomy3'-fluorothymidine-5'-triphosphate (IC50)zidovudine (IC50)
Thymidine kinase, cytosolicHomo sapiens (human)3
Reverse transcriptase/RNaseH Human immunodeficiency virus 10.6633
Protease Human immunodeficiency virus 10.015

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (75.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Akesson-Johansson, A; Cox, S; Harmenberg, J; Vrang, L1
Quan, K; Tao, P; Zhang, X1
Amacker, M; Faraj, A; Gosselin, G; Hübscher, U; Imbach, JL; Maga, G; Mathé, C; Sommadossi, JP; Spadari, S1
Chien, M; Jockusch, S; Ju, J; Kalachikov, S; Kirchdoerfer, RN; Kumar, S; Li, X; Morozova, I; Russo, JJ; Tao, C1

Other Studies

4 other study(ies) available for 3'-fluorothymidine-5'-triphosphate and zidovudine

ArticleYear
Synergistic inhibition of human immunodeficiency virus replication in vitro by combinations of 3'-azido-3'-deoxythymidine and 3'-fluoro-3'-deoxythymidine.
    AIDS research and human retroviruses, 1990, Volume: 6, Issue:10

    Topics: Antiviral Agents; Cell Line; Dideoxynucleosides; Dideoxynucleotides; Drug Synergism; HIV-1; Humans; In Vitro Techniques; Reverse Transcriptase Inhibitors; Thymine Nucleotides; Virus Replication; Zidovudine

1990
The characterization of EIAV reverse transcriptase and its inhibition by 5'-triphosphates of 2'-deoxyuridine analogs, PFA and PAA.
    Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao, 1990, Volume: 5, Issue:3

    Topics: Antiviral Agents; Dideoxynucleotides; Foscarnet; HIV; Infectious Anemia Virus, Equine; Phosphonoacetic Acid; RNA-Directed DNA Polymerase; Thymine Nucleotides; Zidovudine

1990
Molecular basis for the enantioselectivity of HIV-1 reverse transcriptase: role of the 3'-hydroxyl group of the L-(beta)-ribose in chiral discrimination between D- and L-enantiomers of deoxy- and dideoxy-nucleoside triphosphate analogs.
    Nucleic acids research, 1999, Feb-15, Volume: 27, Issue:4

    Topics: Anti-HIV Agents; Carbohydrates; Catalysis; Deoxycytosine Nucleotides; Deoxyribonucleosides; Dideoxynucleosides; Dideoxynucleotides; DNA; Drug Resistance, Microbial; HIV Reverse Transcriptase; Humans; Hydroxyl Radical; Isoleucine; Kinetics; Nevirapine; Recombinant Fusion Proteins; Reverse Transcriptase Inhibitors; Ribose; Templates, Genetic; Thymine Nucleotides; Tyrosine; Zidovudine

1999
Nucleotide analogues as inhibitors of SARS-CoV Polymerase.
    Pharmacology research & perspectives, 2020, Volume: 8, Issue:6

    Topics: Antiviral Agents; Betacoronavirus; Carbamates; Coronavirus Infections; COVID-19; Dideoxynucleotides; Drug Combinations; Heterocyclic Compounds, 4 or More Rings; Humans; Pandemics; Pneumonia, Viral; RNA-Dependent RNA Polymerase; SARS-CoV-2; Sofosbuvir; Thymine Nucleotides; Zidovudine

2020