3'-fluorothymidine-5'-triphosphate has been researched along with zidovudine triphosphate in 5 studies
| Studies (3'-fluorothymidine-5'-triphosphate) | Trials (3'-fluorothymidine-5'-triphosphate) | Recent Studies (post-2010) (3'-fluorothymidine-5'-triphosphate) | Studies (zidovudine triphosphate) | Trials (zidovudine triphosphate) | Recent Studies (post-2010) (zidovudine triphosphate) |
|---|---|---|---|---|---|
| 7 | 0 | 1 | 199 | 4 | 19 |
| Protein | Taxonomy | 3'-fluorothymidine-5'-triphosphate (IC50) | zidovudine triphosphate (IC50) |
|---|---|---|---|
| DNA polymerase catalytic subunit | Human alphaherpesvirus 1 strain KOS | 3.3 | |
| DNA polymerase catalytic subunit | Human alphaherpesvirus 1 strain 17 | 3.3 | |
| DNA polymerase catalytic subunit | Human herpesvirus 3 strain Dumas | 5.8 | |
| DNA polymerase delta catalytic subunit | Homo sapiens (human) | 2.3 | |
| Reverse transcriptase/RNaseH | Human immunodeficiency virus 1 | 0.9835 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (60.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Boyle, NA; Brooks, JL; Bruice, TW; Chen, F; Cook, PD; Ewing, GJ; Fagan, P; Hurd, T; Leeds, JM; Prhavc, M; Rajwanshi, VK; Wang, G | 1 |
| Akesson-Johansson, A; Cox, S; Harmenberg, J; Vrang, L | 1 |
| Quan, K; Tao, P; Zhang, X | 1 |
| Amacker, M; Faraj, A; Gosselin, G; Hübscher, U; Imbach, JL; Maga, G; Mathé, C; Sommadossi, JP; Spadari, S | 1 |
| Chien, M; Jockusch, S; Ju, J; Kalachikov, S; Kirchdoerfer, RN; Kumar, S; Li, X; Morozova, I; Russo, JJ; Tao, C | 1 |
5 other study(ies) available for 3'-fluorothymidine-5'-triphosphate and zidovudine triphosphate
| Article | Year |
|---|---|
Synthesis of 2',3'-dideoxynucleoside 5'-alpha-P-borano-beta,gamma-(difluoromethylene)triphosphates and their inhibition of HIV-1 reverse transcriptase.
Topics: Animals; Anti-HIV Agents; Boron Compounds; Cattle; Deoxyribonucleotides; HIV Reverse Transcriptase; In Vitro Techniques; Reverse Transcriptase Inhibitors; Stereoisomerism | 2005 |
Synergistic inhibition of human immunodeficiency virus replication in vitro by combinations of 3'-azido-3'-deoxythymidine and 3'-fluoro-3'-deoxythymidine.
Topics: Antiviral Agents; Cell Line; Dideoxynucleosides; Dideoxynucleotides; Drug Synergism; HIV-1; Humans; In Vitro Techniques; Reverse Transcriptase Inhibitors; Thymine Nucleotides; Virus Replication; Zidovudine | 1990 |
The characterization of EIAV reverse transcriptase and its inhibition by 5'-triphosphates of 2'-deoxyuridine analogs, PFA and PAA.
Topics: Antiviral Agents; Dideoxynucleotides; Foscarnet; HIV; Infectious Anemia Virus, Equine; Phosphonoacetic Acid; RNA-Directed DNA Polymerase; Thymine Nucleotides; Zidovudine | 1990 |
Molecular basis for the enantioselectivity of HIV-1 reverse transcriptase: role of the 3'-hydroxyl group of the L-(beta)-ribose in chiral discrimination between D- and L-enantiomers of deoxy- and dideoxy-nucleoside triphosphate analogs.
Topics: Anti-HIV Agents; Carbohydrates; Catalysis; Deoxycytosine Nucleotides; Deoxyribonucleosides; Dideoxynucleosides; Dideoxynucleotides; DNA; Drug Resistance, Microbial; HIV Reverse Transcriptase; Humans; Hydroxyl Radical; Isoleucine; Kinetics; Nevirapine; Recombinant Fusion Proteins; Reverse Transcriptase Inhibitors; Ribose; Templates, Genetic; Thymine Nucleotides; Tyrosine; Zidovudine | 1999 |
Nucleotide analogues as inhibitors of SARS-CoV Polymerase.
Topics: Antiviral Agents; Betacoronavirus; Carbamates; Coronavirus Infections; COVID-19; Dideoxynucleotides; Drug Combinations; Heterocyclic Compounds, 4 or More Rings; Humans; Pandemics; Pneumonia, Viral; RNA-Dependent RNA Polymerase; SARS-CoV-2; Sofosbuvir; Thymine Nucleotides; Zidovudine | 2020 |