3'-fluorothymidine-5'-triphosphate and thymidine 5'-triphosphate

3'-fluorothymidine-5'-triphosphate has been researched along with thymidine 5'-triphosphate in 2 studies

Compound Research Comparison

Studies (3'-fluorothymidine-5'-triphosphate)	Trials (3'-fluorothymidine-5'-triphosphate)	Recent Studies (post-2010) (3'-fluorothymidine-5'-triphosphate)	Studies (thymidine 5'-triphosphate)	Trials (thymidine 5'-triphosphate)	Recent Studies (post-2010) (thymidine 5'-triphosphate)
7	0	1	751	4	92

Protein Interaction Comparison

Protein	Taxonomy	3'-fluorothymidine-5'-triphosphate (IC50)	thymidine 5'-triphosphate (IC50)
Chain A, Deoxynucleoside kinase	Drosophila melanogaster (fruit fly)		1000
DNA polymerase beta	Homo sapiens (human)		1.4

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (50.00)	18.2507
2000's	1 (50.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Boyle, NA; Brooks, JL; Bruice, TW; Chen, F; Cook, PD; Ewing, GJ; Fagan, P; Hurd, T; Leeds, JM; Prhavc, M; Rajwanshi, VK; Wang, G	1
Amacker, M; Faraj, A; Gosselin, G; Hübscher, U; Imbach, JL; Maga, G; Mathé, C; Sommadossi, JP; Spadari, S	1

Other Studies

2 other study(ies) available for 3'-fluorothymidine-5'-triphosphate and thymidine 5'-triphosphate

Article	Year
Synthesis of 2',3'-dideoxynucleoside 5'-alpha-P-borano-beta,gamma-(difluoromethylene)triphosphates and their inhibition of HIV-1 reverse transcriptase. Journal of medicinal chemistry, 2005, Apr-07, Volume: 48, Issue:7 Topics: Animals; Anti-HIV Agents; Boron Compounds; Cattle; Deoxyribonucleotides; HIV Reverse Transcriptase; In Vitro Techniques; Reverse Transcriptase Inhibitors; Stereoisomerism	2005
Molecular basis for the enantioselectivity of HIV-1 reverse transcriptase: role of the 3'-hydroxyl group of the L-(beta)-ribose in chiral discrimination between D- and L-enantiomers of deoxy- and dideoxy-nucleoside triphosphate analogs. Nucleic acids research, 1999, Feb-15, Volume: 27, Issue:4 Topics: Anti-HIV Agents; Carbohydrates; Catalysis; Deoxycytosine Nucleotides; Deoxyribonucleosides; Dideoxynucleosides; Dideoxynucleotides; DNA; Drug Resistance, Microbial; HIV Reverse Transcriptase; Humans; Hydroxyl Radical; Isoleucine; Kinetics; Nevirapine; Recombinant Fusion Proteins; Reverse Transcriptase Inhibitors; Ribose; Templates, Genetic; Thymine Nucleotides; Tyrosine; Zidovudine	1999

Article

Year

Synthesis of 2',3'-dideoxynucleoside 5'-alpha-P-borano-beta,gamma-(difluoromethylene)triphosphates and their inhibition of HIV-1 reverse transcriptase.

Journal of medicinal chemistry, 2005, Apr-07, Volume: 48, Issue:7

Topics: Animals; Anti-HIV Agents; Boron Compounds; Cattle; Deoxyribonucleotides; HIV Reverse Transcriptase; In Vitro Techniques; Reverse Transcriptase Inhibitors; Stereoisomerism

2005

Molecular basis for the enantioselectivity of HIV-1 reverse transcriptase: role of the 3'-hydroxyl group of the L-(beta)-ribose in chiral discrimination between D- and L-enantiomers of deoxy- and dideoxy-nucleoside triphosphate analogs.

Nucleic acids research, 1999, Feb-15, Volume: 27, Issue:4

Topics: Anti-HIV Agents; Carbohydrates; Catalysis; Deoxycytosine Nucleotides; Deoxyribonucleosides; Dideoxynucleosides; Dideoxynucleotides; DNA; Drug Resistance, Microbial; HIV Reverse Transcriptase; Humans; Hydroxyl Radical; Isoleucine; Kinetics; Nevirapine; Recombinant Fusion Proteins; Reverse Transcriptase Inhibitors; Ribose; Templates, Genetic; Thymine Nucleotides; Tyrosine; Zidovudine

1999