Page last updated: 2024-09-04

3'-deoxycytidine and cytarabine

3'-deoxycytidine has been researched along with cytarabine in 1 studies

*Cytarabine: A pyrimidine nucleoside analog that is used mainly in the treatment of leukemia, especially acute non-lymphoblastic leukemia. Cytarabine is an antimetabolite antineoplastic agent that inhibits the synthesis of DNA. Its actions are specific for the S phase of the cell cycle. It also has antiviral and immunosuppressant properties. (From Martindale, The Extra Pharmacopoeia, 30th ed, p472) [MeSH]

*Cytarabine: A pyrimidine nucleoside analog that is used mainly in the treatment of leukemia, especially acute non-lymphoblastic leukemia. Cytarabine is an antimetabolite antineoplastic agent that inhibits the synthesis of DNA. Its actions are specific for the S phase of the cell cycle. It also has antiviral and immunosuppressant properties. (From Martindale, The Extra Pharmacopoeia, 30th ed, p472) [MeSH]

Compound Research Comparison

Studies
(3'-deoxycytidine)
Trials
(3'-deoxycytidine)
Recent Studies (post-2010)
(3'-deoxycytidine)
Studies
(cytarabine)
Trials
(cytarabine)
Recent Studies (post-2010) (cytarabine)
50115,4872,4243,188

Protein Interaction Comparison

ProteinTaxonomy3'-deoxycytidine (IC50)cytarabine (IC50)
nuclear receptor coactivator 3 isoform aHomo sapiens (human)7.533
E3 ubiquitin-protein ligase Mdm2Homo sapiens (human)0.02

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Birnbaum, GI; Brankovan, V; Cheng, YC; Ghazzouli, I; Giziewicz, J; Lin, TS; Liu, MC; Prusoff, WH; Shen, ZY; Yang, JH1

Other Studies

1 other study(ies) available for 3'-deoxycytidine and cytarabine

ArticleYear
Synthesis and anticancer activity of various 3'-deoxy pyrimidine nucleoside analogues and crystal structure of 1-(3-deoxy-beta-D-threo-pentofuranosyl)cytosine.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:2

    Topics: Animals; Antineoplastic Agents; Cell Line; Chemical Phenomena; Chemistry; Cytarabine; Leukemia L1210; Leukemia P388; Mice; Pyrimidine Nucleosides; Sarcoma 180; Structure-Activity Relationship; X-Ray Diffraction

1991