Page last updated: 2024-09-05

3'-demethylnobiletin and 3',4'-didemethylnobiletin

3'-demethylnobiletin has been researched along with 3',4'-didemethylnobiletin in 5 studies

Compound Research Comparison

Studies
(3'-demethylnobiletin)
Trials
(3'-demethylnobiletin)
Recent Studies (post-2010)
(3'-demethylnobiletin)
Studies
(3',4'-didemethylnobiletin)
Trials
(3',4'-didemethylnobiletin)
Recent Studies (post-2010) (3',4'-didemethylnobiletin)
7031206

Protein Interaction Comparison

ProteinTaxonomy3'-demethylnobiletin (IC50)3',4'-didemethylnobiletin (IC50)
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)0.0324

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's3 (60.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dushenkov, S; Ho, CT; Lai, CS; Li, S; Lo, CY; Pan, MH1
Ho, CT; Lai, CS; Li, S; Lo, CY; Pan, MH; Sang, S; Yang, CS1
Kosano, H; Miyata, Y; Natsugari, H; Okuyama, Y; Oshitari, T; Takahashi, H2
Gao, Z; Song, M; Wang, M; Wu, X; Xiao, H; Xu, F; Zhang, G; Zheng, J1

Other Studies

5 other study(ies) available for 3'-demethylnobiletin and 3',4'-didemethylnobiletin

ArticleYear
Isolation and syntheses of polymethoxyflavones and hydroxylated polymethoxyflavones as inhibitors of HL-60 cell lines.
    Bioorganic & medicinal chemistry, 2007, May-15, Volume: 15, Issue:10

    Topics: Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Proliferation; Chromatography, High Pressure Liquid; Citrus; Flavones; Fruit; HL-60 Cells; Humans; Hydroxylation; Indicators and Reagents; Magnetic Resonance Spectroscopy; Plant Extracts; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet

2007
Anti-inflammatory property of the urinary metabolites of nobiletin in mouse.
    Bioorganic & medicinal chemistry letters, 2007, Sep-15, Volume: 17, Issue:18

    Topics: Animals; Anti-Inflammatory Agents; Cell Line; Chromatography, High Pressure Liquid; Flavones; Mice; Tandem Mass Spectrometry

2007
Nobiletin metabolites: synthesis and inhibitory activity against matrix metalloproteinase-9 production.
    Bioorganic & medicinal chemistry letters, 2011, Aug-01, Volume: 21, Issue:15

    Topics: Acetophenones; Epithelial Cells; Flavones; Humans; Hydroxybenzoates; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors

2011
B-Ring-modified and/or 5-demethylated nobiletin congeners: inhibitory activity against pro-MMP-9 production.
    Bioorganic & medicinal chemistry, 2011, Dec-01, Volume: 19, Issue:23

    Topics: Cell Line; Enzyme Precursors; Epithelial Cells; Flavones; Humans; Lens, Crystalline; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Protease Inhibitors; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha

2011
Chemopreventive effects of nobiletin and its colonic metabolites on colon carcinogenesis.
    Molecular nutrition & food research, 2015, Volume: 59, Issue:12

    Topics: Administration, Oral; Animals; Anticarcinogenic Agents; Apoptosis; Cell Line, Tumor; Colitis; Colonic Neoplasms; Cytokines; Flavones; Humans; Male; Mice, Inbred Strains; Neoplasms, Experimental

2015