Compounds > 3--deamino-3--hydroxydoxorubicin

3--deamino-3--hydroxydoxorubicin and 3--deamino-3--hydroxydaunorubicin

3--deamino-3--hydroxydoxorubicin has been researched along with 3--deamino-3--hydroxydaunorubicin* in 1 studies

Other Studies

1 other study(ies) available for 3--deamino-3--hydroxydoxorubicin and 3--deamino-3--hydroxydaunorubicin

Article	Year
3'-Deamino-4'-epi-3'-hydroxy-daunorubicin and -doxorubicin. Synthesis and antitumor activity. The Journal of antibiotics, 1984, Volume: 37, Issue:12 3'-Deamino-4'-epi-3'-hydroxy-daunorubicin (11) and -doxorubicin (14) have been synthesized. In the in vivo murine P-388 lymphocytic leukemia assay, these two compounds were more active than daunorubicin (1) and doxorubicin (2), respectively. Comparative studies in the P-388 assay indicated 3'-deamino-3'-hydroxydoxorubicin (3) to be more active than its 4'-epimer 14. Topics: Animals; Daunorubicin; Doxorubicin; Epirubicin; Leukemia P388; Mice; Structure-Activity Relationship	1984

Article

Year

3'-Deamino-4'-epi-3'-hydroxy-daunorubicin and -doxorubicin. Synthesis and antitumor activity.

The Journal of antibiotics, 1984, Volume: 37, Issue:12

3'-Deamino-4'-epi-3'-hydroxy-daunorubicin (11) and -doxorubicin (14) have been synthesized. In the in vivo murine P-388 lymphocytic leukemia assay, these two compounds were more active than daunorubicin (1) and doxorubicin (2), respectively. Comparative studies in the P-388 assay indicated 3'-deamino-3'-hydroxydoxorubicin (3) to be more active than its 4'-epimer 14.

Topics: Animals; Daunorubicin; Doxorubicin; Epirubicin; Leukemia P388; Mice; Structure-Activity Relationship

1984