Compounds > 3'-deamino-3'-(3-cyano-4-morpholinyl)doxorubicin
Page last updated: 2024-09-05

3'-deamino-3'-(3-cyano-4-morpholinyl)doxorubicin and verapamil

3'-deamino-3'-(3-cyano-4-morpholinyl)doxorubicin has been researched along with verapamil in 2 studies

Compound Research Comparison

Studies
(3'-deamino-3'-(3-cyano-4-morpholinyl)doxorubicin)		Trials
(3'-deamino-3'-(3-cyano-4-morpholinyl)doxorubicin)		Recent Studies (post-2010)
(3'-deamino-3'-(3-cyano-4-morpholinyl)doxorubicin)		Studies
(verapamil)		Trials
(verapamil)		Recent Studies (post-2010) (verapamil)
380017,6211,5272,067

Protein Interaction Comparison

ProteinTaxonomy3'-deamino-3'-(3-cyano-4-morpholinyl)doxorubicin (IC50)verapamil (IC50)
Solute carrier family 22 member 1 Homo sapiens (human)6.8
Voltage-dependent L-type calcium channel subunit alpha-1FHomo sapiens (human)0.2
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.297
ATP-dependent translocase ABCB1Mus musculus (house mouse)2
ATP-dependent translocase ABCB1Homo sapiens (human)2.2346
Cytochrome P450 3A4Homo sapiens (human)3.8008
Alpha-2A adrenergic receptorHomo sapiens (human)0.579
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)3.02
ATP-dependent translocase ABCB1Mus musculus (house mouse)10
Catechol O-methyltransferaseHomo sapiens (human)0.2
Potassium voltage-gated channel subfamily A member 3Homo sapiens (human)8
Histamine H2 receptorHomo sapiens (human)2.59
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.442
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.297
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)3.02
Sodium-dependent serotonin transporterHomo sapiens (human)0.24
Multidrug resistance-associated protein 1 Homo sapiens (human)5.598
D(3) dopamine receptorHomo sapiens (human)0.186
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.165
5-hydroxytryptamine receptor 7Cavia porcellus (domestic guinea pig)6.8
Voltage-dependent L-type calcium channel subunit alpha-1D Homo sapiens (human)0.2
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)0.3945
Voltage-dependent L-type calcium channel subunit alpha-1SHomo sapiens (human)0.2
Voltage-dependent L-type calcium channel subunit alpha-1CHomo sapiens (human)0.175
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)1.1934

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19902 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gordon, GR; Johl, JS; Peters, JH; Streeter, DG1
Acton, EM; Peters, JH; Streeter, DG; Taylor, DL1

Other Studies

2 other study(ies) available for 3'-deamino-3'-(3-cyano-4-morpholinyl)doxorubicin and verapamil

ArticleYear
Uptake and retention of morpholinyl anthracyclines by adriamycin-sensitive and -resistant P388 cells.
    Cancer chemotherapy and pharmacology, 1986, Volume: 16, Issue:3

    Topics: Animals; Antibiotics, Antineoplastic; Cell Line; Doxorubicin; Drug Resistance; Leukemia P388; Leukemia, Experimental; Mice; Naphthacenes; Structure-Activity Relationship; Verapamil

1986
Comparative cytotoxicities of various morpholinyl anthracyclines.
    Cancer chemotherapy and pharmacology, 1985, Volume: 14, Issue:2

    Topics: Animals; Antineoplastic Agents; Cell Division; Cell Line; Doxorubicin; Drug Resistance; Drug Synergism; Leukemia P388; Leukemia, Experimental; Mice; Time Factors; Verapamil

1985