3'-azido-3'-deoxy-5'-o-beta-glucopyranuronosylthymidine has been researched along with zidovudine in 50 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 3 (6.00) | 18.7374 |
1990's | 42 (84.00) | 18.2507 |
2000's | 3 (6.00) | 29.6817 |
2010's | 1 (2.00) | 24.3611 |
2020's | 1 (2.00) | 2.80 |
Authors | Studies |
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Gallo, JM; Mehta, M; Qian, MX; Swagler, AR; Vishwanathan, CT | 1 |
Borvák, J; Kasanická, J; Mayer, V | 1 |
Bonnez, W; Marder, V; Morse, GD; Olson, J; Plank, C; Portmore, AC; Reichman, RC; Taylor, C | 1 |
Biollaz, J; Chatton, JY; Chave, JP; Glauser, MP; Munafo, A; Roch-Ramel, F; Steinhäuslin, F | 1 |
Bennett, WM; Gilbert, DN; Kohlhepp, SJ; Kremer, D; Munar, MY; Stinnett, EA; Swan, SK; Young, EW | 1 |
Back, DJ; Colbert, J; Howe, JL | 1 |
Gallo, JM; Qian, MX; Swagler, AR | 1 |
Finco, TS; Gallo, JM; Qian, MX | 1 |
Back, DJ; Breckenridge, AM; Sim, SM | 1 |
Ahmed, AE; Douidar, SM; Loh, JP; Nokta, M; Pollard, RB | 1 |
Cretton, EM; Sommadossi, JP | 1 |
Bevan, RJ; Cretton, EM; Goudgaon, NM; Schinazi, RF; Sommadossi, JP; Xie, MY | 1 |
Stretcher, BN | 1 |
Kamali, F; Rawlins, MD | 1 |
Chaput, JC; Colin, JN; Delfraissy, JF; Naveau, S; Singlas, E; Taburet, AM; Zorza, G | 1 |
Blum, MR; Broder, S; de Miranda, P; Good, SS; Myers, CE; Thomas, RV; Yarchoan, R | 1 |
Colaneri, S; Fillastre, JP; Pioger, JC; Singlas, E; Taburet, AM | 1 |
Balfour, HH; Chinnock, BJ; de Miranda, P; Fletcher, CV; Henry, K; Quinn, RP | 1 |
Asgari, M; Back, DJ | 1 |
Cameron, W; Gallicano, K; Garber, G; Pakuts, A; Sahai, J | 1 |
Agrawal, KC; Akula, S; George, WJ; Greenspan, DL; Hyslop, NE; Lertora, JJ; Rege, AB | 1 |
Plasse, JC; Schrive, I | 1 |
Bezek, S; Bohov, P; Kukan, M | 1 |
Beijnen, JH; Burger, DM; Koks, CH; Meenhorst, PL; Underberg, WJ; van der Heijde, JF | 1 |
Back, DJ; Barry, M; Beeching, N; Bergin, C; Breckenridge, AM; Howe, JL; Mulcahy, F; Nye, F; Ormesher, S | 1 |
Domin, BA; Mahony, WB; Zimmerman, TP | 1 |
Back, DJ; Barry, M; Beeching, N; Breckenridge, AM; Howe, JL; Nye, F; Swart, AM; Weller, IV | 1 |
Czochralska, B; Kawczyński, W; Shugar, D | 1 |
Beijnen, JH; Burger, DM; Koks, CH; Meenhorst, PL | 1 |
Boucher, FD; Crain, MJ; Elkins, MM; McKinney, R; Mirochnick, M; Modlin, JF; Pelton, S; Ruff, A; Weller, S; Wilfert, C | 1 |
Gallo, JM; Mehta, M; Qian, M; Swagler, AR | 1 |
Daniel, SS; Garland, M; Myers, MM; Stark, RI; Szeto, HH; Tropper, PJ | 2 |
Brouwer, KL; Cheeseman, SH; Eyster, E; Lemon, SM; Moore, KH; Opheim, K; Raasch, RH; van der Horst, CM | 1 |
Cameron, DW; Gallicano, K; Pakuts, A; Sahai, J; Seguin, I; Swick, L | 1 |
Nadal, T; Ortuño, J; Pascual, JA | 1 |
Bacracheva, N; Kamali, F | 1 |
Back, D; Bland, M; Fleming, SC; Griffin, GE; Kapembwa, MS; Orr, M; Wells, C | 1 |
Fried, K; Wainer, IW | 1 |
Akula, SK; Dejace, PM; Dreisbach, AW; Lertora, JJ; Rege, AB | 1 |
Binienda, ZK; Gillam, MP; Lipe, GW; Patterson, TA; Sandberg, JA; Slikker, W | 1 |
Barthel, B; Brockmeyer, NH; Goos, M; Mertins, L; Tillmann, I | 1 |
Pei, JC; Pike, IM; Van Harken, DR; Wagner, J | 1 |
Fayz, S; Inaba, T | 1 |
Motohashi, M; Nakagawa, Y; Okuda, T | 1 |
Collier, AC; Keelan, JA; Mitchell, MD; Paxton, JW; Tingle, MD; Van Zijl, PE | 1 |
Bauman, JN; Court, MH; Goosen, TC; Hurst, SI; Menning, LC; Milad, M; Peterkin, V; Tugnait, M; Williams, JA | 1 |
Chan, C; Flexner, C; Lee, LS; Lietman, PS; Parsons, TL; Wise, SD | 1 |
Hanioka, N; Ikushiro, S; Nagaoka, K; Narimatsu, S; Yamano, S | 1 |
Ambati, J; Ambati, K; Ambati, M; Ambati, VL; Apicella, I; Baker, KL; Gelfand, BD; Marion, KM; Narendran, S; Pereira, F; Sadda, SR; Varshney, A; Wang, SB; Yerramothu, P | 1 |
2 review(s) available for 3'-azido-3'-deoxy-5'-o-beta-glucopyranuronosylthymidine and zidovudine
Article | Year |
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State-of-the-art of zidovudine monitoring.
Topics: Adult; Chromatography, High Pressure Liquid; Fluorescence Polarization Immunoassay; HIV Infections; Humans; Infant; Radioimmunoassay; Zidovudine | 1991 |
Column-switching techniques in the biomedical analysis of stereoisomeric drugs: why, how and when.
Topics: Animals; Chromatography, High Pressure Liquid; Humans; Leucovorin; Stereoisomerism; Tamoxifen; Verapamil; Zidovudine | 1997 |
9 trial(s) available for 3'-azido-3'-deoxy-5'-o-beta-glucopyranuronosylthymidine and zidovudine
Article | Year |
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Trimethoprim, alone or in combination with sulphamethoxazole, decreases the renal excretion of zidovudine and its glucuronide.
Topics: Adult; Drug Interactions; Female; HIV Infections; Humans; Infusions, Intravenous; Male; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination; Zidovudine | 1992 |
Pharmacokinetics of simultaneously administered zidovudine and didanosine in HIV-seropositive male patients.
Topics: Adult; Cross-Over Studies; Didanosine; Drug Interactions; Drug Therapy, Combination; HIV Seropositivity; Humans; Male; Metabolic Clearance Rate; Zidovudine | 1995 |
Pharmacokinetic interaction between zidovudine and valproic acid in patients infected with human immunodeficiency virus.
Topics: Adult; Biological Availability; Drug Synergism; Half-Life; HIV Infections; Humans; Linear Models; Male; Middle Aged; Valproic Acid; Zidovudine | 1994 |
Pharmacokinetics of zidovudine and dideoxyinosine alone and in combination in patients with the acquired immunodeficiency syndrome.
Topics: Acquired Immunodeficiency Syndrome; Administration, Oral; Adult; Chromatography, High Pressure Liquid; Didanosine; Drug Interactions; Drug Therapy, Combination; Half-Life; Humans; Male; Metabolic Clearance Rate; Middle Aged; Zidovudine | 1994 |
Phase I evaluation of zidovudine administered to infants exposed at birth to the human immunodeficiency virus.
Topics: Administration, Oral; Anemia; Drug Administration Schedule; Drug Tolerance; Female; HIV Infections; Humans; Infant; Infant, Newborn; Infusions, Intravenous; Male; Maternal-Fetal Exchange; Pregnancy; Pregnancy Complications, Infectious; Zidovudine | 1993 |
Pharmacokinetics and bioavailability of zidovudine and its glucuronidated metabolite in patients with human immunodeficiency virus infection and hepatic disease (AIDS Clinical Trials Group protocol 062).
Topics: Administration, Oral; Adult; Antiviral Agents; Biological Availability; Female; HIV Infections; Humans; Injections, Intravenous; Liver Diseases; Male; Middle Aged; Zidovudine | 1995 |
Effect of rifabutin on the pharmacokinetics of zidovudine in patients infected with human immunodeficiency virus.
Topics: Adult; Antiviral Agents; Drug Therapy, Combination; Female; HIV Infections; Humans; Male; Reverse Transcriptase Inhibitors; Rifabutin; Zidovudine | 1995 |
Pharmacokinetic interaction of megestrol acetate with zidovudine in human immunodeficiency virus-infected patients.
Topics: Administration, Oral; Adult; Anti-HIV Agents; Appetite Stimulants; Area Under Curve; Cross-Over Studies; Drug Administration Schedule; Drug Interactions; Half-Life; HIV Infections; Humans; Male; Megestrol Acetate; Middle Aged; Radioimmunoassay; Zidovudine | 1997 |
Possible differential induction of phase 2 enzyme and antioxidant pathways by american ginseng, Panax quinquefolius.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Anti-HIV Agents; Antioxidants; Area Under Curve; Biomarkers, Pharmacological; Cells, Cultured; Chromatography, High Pressure Liquid; Deoxyguanosine; Dose-Response Relationship, Drug; Drug Interactions; F2-Isoprostanes; Female; Ginsenosides; HIV Infections; HIV Protease Inhibitors; Humans; Male; Metabolic Clearance Rate; NAD(P)H Dehydrogenase (Quinone); Oxidative Stress; Panax; Phytotherapy; Plant Extracts; Zidovudine | 2008 |
39 other study(ies) available for 3'-azido-3'-deoxy-5'-o-beta-glucopyranuronosylthymidine and zidovudine
Article | Year |
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Pharmacokinetic evaluation of drug interactions with anti-human immunotrophic virus (HIV) Drugs. III. 2',3'-Dideoxycytidine (ddC) and zidovudine in monkeys.
Topics: Animals; Antiviral Agents; Drug Interactions; HIV; Macaca fascicularis; Male; Zalcitabine; Zidovudine | 1992 |
HPLC-monitoring of AZT in HIV-infected patient's plasma: a critical study.
Topics: Calibration; Chromatography, High Pressure Liquid; HIV Infections; Humans; Reference Standards; Reproducibility of Results; Zidovudine | 1992 |
Intravenous and oral zidovudine pharmacokinetics and coagulation effects in asymptomatic human immunodeficiency virus-infected hemophilia patients.
Topics: Administration, Oral; Adult; Blood Coagulation; Chromatography, High Pressure Liquid; Half-Life; Hemophilia A; HIV Infections; Humans; Injections, Intravenous; Male; Metabolic Clearance Rate; Middle Aged; Zidovudine | 1992 |
Zidovudine pharmacokinetics in five HIV seronegative patients undergoing continuous ambulatory peritoneal dialysis.
Topics: Administration, Oral; Adult; Dialysis Solutions; HIV Seropositivity; Humans; Kidney Diseases; Male; Middle Aged; Peritoneal Dialysis, Continuous Ambulatory; Reproducibility of Results; Zidovudine | 1992 |
Extrahepatic metabolism of zidovudine.
Topics: Adolescent; Adult; Duodenum; Humans; In Vitro Techniques; Kidney; Male; Microsomes; Microsomes, Liver; Middle Aged; Zidovudine | 1992 |
Pharmacokinetics of anti-HIV nucleosides in microswine.
Topics: Animals; Antiviral Agents; Chromatography, High Pressure Liquid; Didanosine; Half-Life; HIV; Male; Nucleosides; Swine; Swine, Miniature; Zalcitabine; Zidovudine | 1991 |
Rapid and simultaneous determination of zidovudine and its glucuronide metabolite in plasma and urine. Application to the pharmacokinetic interaction of zidovudine and probenecid in the monkey.
Topics: Animals; Chromatography, Liquid; Drug Interactions; Half-Life; Haplorhini; Probenecid; Zidovudine | 1991 |
The effect of various drugs on the glucuronidation of zidovudine (azidothymidine; AZT) by human liver microsomes.
Topics: Acetaminophen; Adolescent; Adult; Chromatography, High Pressure Liquid; Didanosine; Drug Interactions; Female; Glucuronosyltransferase; Humans; Male; Microsomes, Liver; Middle Aged; Salicylates; Sulfanilamide; Sulfanilamides; Zidovudine | 1991 |
Metabolic interaction of recombinant interferon-beta and zidovudine in AIDS patients.
Topics: Acquired Immunodeficiency Syndrome; Administration, Oral; Adult; Biological Availability; Chromatography, High Pressure Liquid; Demography; Drug Therapy, Combination; Half-Life; Humans; Injections, Subcutaneous; Interferon Type I; Kidney Function Tests; Kinetics; Liver Function Tests; Male; Recombinant Proteins; Zidovudine | 1991 |
Modulation of 3'-azido-3'-deoxythymidine catabolism by probenecid and acetaminophen in freshly isolated rat hepatocytes.
Topics: Acetaminophen; Animals; Body Fluid Compartments; Cells, Cultured; Chromatography, High Pressure Liquid; Dideoxynucleosides; Drug Interactions; Humans; Liver; Probenecid; Rats; Rats, Inbred Strains; Zidovudine | 1991 |
Catabolism of 3'-azido-3'-deoxythymidine in hepatocytes and liver microsomes, with evidence of formation of 3'-amino-3'-deoxythymidine, a highly toxic catabolite for human bone marrow cells.
Topics: Animals; Bone Marrow; Bone Marrow Cells; Dideoxynucleosides; Extracellular Space; Gas Chromatography-Mass Spectrometry; Hematopoietic Stem Cells; Humans; Intracellular Fluid; Liver; Microsomes, Liver; Rats; Rats, Inbred Strains; Time Factors; Tritium; Zidovudine | 1991 |
Simple and rapid assay for zidovudine and zidovudine glucuronide in plasma using high-performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Hot Temperature; Humans; Trichloroacetic Acid; Zidovudine | 1990 |
Pharmacokinetics of zidovudine in patients with liver cirrhosis.
Topics: Adult; Humans; Liver Cirrhosis; Middle Aged; Zidovudine | 1990 |
Alteration of zidovudine pharmacokinetics by probenecid in patients with AIDS or AIDS-related complex.
Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Complex; Drug Interactions; Drug Therapy, Combination; Half-Life; Humans; Male; Middle Aged; Probenecid; Regression Analysis; Zidovudine | 1989 |
Comparative pharmacokinetics of zidovudine (AZT) and its metabolite (G.AZT) in healthy subjects and HIV seropositive patients.
Topics: Adult; HIV Seropositivity; Humans; Male; Middle Aged; Zidovudine | 1989 |
Concurrent zidovudine levels in semen and serum determined by radioimmunoassay in patients with AIDS or AIDS-related complex.
Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Complex; Chromatography, High Pressure Liquid; Humans; Male; Radioimmunoassay; Semen; Thymidine; Zidovudine | 1988 |
Effect of azoles on the glucuronidation of zidovudine by human liver UDP-glucuronosyltransferase.
Topics: Antifungal Agents; Antiviral Agents; Drug Interactions; Fluconazole; Glucuronosyltransferase; Humans; Itraconazole; Ketoconazole; Liver; Zidovudine | 1995 |
Quantification of zidovudine and one of its metabolites in plasma and urine by solid-phase extraction and high-performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Humans; Molecular Structure; Sensitivity and Specificity; Zidovudine | 1994 |
Hepatobiliary disposition of 3'-azido-3'-deoxythymidine (AZT) in the rat: effect of phenobarbitone induction.
Topics: Animals; Bile; Bone Marrow; Cattle; Cell Survival; Cells, Cultured; Chromatography, Thin Layer; Dinitrophenols; Dose-Response Relationship, Drug; Drug Interactions; Duodenum; Glucuronosyltransferase; Humans; Liver; Male; Phenobarbital; Potassium Cyanide; Rats; Rats, Wistar; Temperature; Zidovudine | 1994 |
Short-term, combined use of paracetamol and zidovudine does not alter the pharmacokinetics of either drug.
Topics: Acetaminophen; Acquired Immunodeficiency Syndrome; Adult; Drug Interactions; Drug Therapy, Combination; Humans; Male; Zidovudine | 1994 |
Inhibition of thymidine transport by 3'-azido-3'-deoxythymidine and its metabolites.
Topics: Biological Transport; Dideoxynucleosides; Erythrocytes; Humans; Thymidine; Zidovudine | 1993 |
Zidovudine pharmacokinetics in zidovudine-induced bone marrow toxicity.
Topics: Administration, Oral; Adult; Animals; Bone Marrow Diseases; Chromatography, High Pressure Liquid; HIV Infections; Humans; Male; Middle Aged; Zidovudine | 1994 |
Electrochemical reduction products of azido nucleosides, including zidovudine (AZT): mechanisms and relevance to their intracellular metabolism.
Topics: Antiviral Agents; Dideoxynucleotides; Electrochemistry; Electrolysis; Intracellular Fluid; Nucleosides; Oxidation-Reduction; Polarography; Thymine Nucleotides; Zidovudine | 1993 |
Pharmacokinetic interaction between rifampin and zidovudine.
Topics: Adult; Dose-Response Relationship, Drug; Drug Interactions; Humans; Male; Middle Aged; Rifampin; Tuberculosis; Zidovudine | 1993 |
Pharmacokinetic evaluation of drug interactions with anti-human immunodeficiency virus drugs. VI. Effect of the calcium channel blocker nimodipine on zidovudine kinetics in monkeys.
Topics: Animals; Calcium Channel Blockers; Drug Interactions; Injections, Intravenous; Macaca fascicularis; Male; Models, Biological; Nimodipine; Random Allocation; Zidovudine | 1993 |
Zidovudine kinetics in the pregnant baboon.
Topics: Absorption; Administration, Oral; Animals; Animals, Newborn; Antiviral Agents; Biological Availability; Female; Fetal Blood; Gestational Age; Half-Life; Infusions, Intravenous; Maternal-Fetal Exchange; Papio; Pregnancy; Pregnancy, Animal; Tissue Distribution; Zidovudine | 1996 |
Rapid and sensitive determination of zidovudine and zidovudine glucuronide in human plasma by ion-pair high-performance liquid chromatography.
Topics: Antiviral Agents; Chromatography, High Pressure Liquid; Humans; Hydrogen-Ion Concentration; Quality Control; Reproducibility of Results; Sensitivity and Specificity; Zidovudine | 1996 |
Lack of interaction between zidovudine and 4-methyl-amino-antipyrine, the active metabolite of metamizole, in human liver in vitro.
Topics: Antiviral Agents; Dipyrone; Drug Interactions; Glucuronates; Humans; In Vitro Techniques; Male; Microsomes, Liver; Pyrazolones; White People; Zidovudine | 1995 |
Impaired absorption of zidovudine in patients with AIDS-related small intestinal disease.
Topics: Acquired Immunodeficiency Syndrome; Adult; Chronic Disease; Diarrhea; Humans; Intestine, Small; Male; Middle Aged; Triolein; Zidovudine | 1996 |
Valproic acid increases cerebrospinal fluid zidovudine levels in a patient with AIDS.
Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS Dementia Complex; Anticonvulsants; Drug Interactions; Humans; Kinetics; Male; Valproic Acid; Zidovudine | 1997 |
Transplacental pharmacokinetics and fetal distribution of azidothymidine, its glucuronide, and phosphorylated metabolites in late-term rhesus macaques after maternal infusion.
Topics: Animals; Anti-HIV Agents; Female; Fetus; Macaca mulatta; Maternal-Fetal Exchange; Pregnancy; Pregnancy, Animal; Tissue Distribution; Zidovudine | 1997 |
Pharmacokinetic interaction of fluconazole and zidovudine in HIV-positive patients.
Topics: 17-Hydroxycorticosteroids; Acquired Immunodeficiency Syndrome; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antifungal Agents; Antipyrine; Candidiasis, Oral; Drug Interactions; Drug Therapy, Combination; Fluconazole; Half-Life; Humans; Hydrocortisone; Male; Zidovudine | 1997 |
Zidovudine azido-reductase in human liver microsomes: activation by ethacrynic acid, dipyridamole, and indomethacin and inhibition by human immunodeficiency virus protease inhibitors.
Topics: Chromatography, Thin Layer; Dipyridamole; Enzyme Activation; Enzyme Inhibitors; Enzyme Repression; Ethacrynic Acid; Humans; Indomethacin; Microsomes, Liver; Oxidoreductases; Zidovudine | 1998 |
Placental transfer and fetal metabolism of zidovudine in the baboon.
Topics: Amniotic Fluid; Analysis of Variance; Animals; Female; Fetal Blood; Fetus; Half-Life; Maternal-Fetal Exchange; Metabolic Clearance Rate; Papio; Placenta; Pregnancy; Zidovudine | 1998 |
Complete two-dimensional separation for analysis of acidic compounds in plasma using column-switching reversed-phase liquid chromatography.
Topics: Acids; Animals; Calibration; Chromatography, Liquid; Probenecid; Rats; Reproducibility of Results; Zidovudine | 1999 |
Human placental glucuronidation and transport of 3'azido-3'-deoxythymidine and uridine diphosphate glucuronic acid.
Topics: Biological Transport; Dose-Response Relationship, Drug; Female; Humans; Placenta; Uridine Diphosphate Glucuronic Acid; Zidovudine | 2004 |
Udp-glucuronosyltransferase 2b7 is the major enzyme responsible for gemcabene glucuronidation in human liver microsomes.
Topics: Caproates; Cells, Cultured; Enzyme Inhibitors; Glucuronosyltransferase; Humans; Microsomes, Liver; Minor Histocompatibility Antigens; Phenotype; Recombinant Proteins; Zidovudine | 2005 |
The effects of N-glycosylation on the glucuronidation of zidovudine and morphine by UGT2B7 expressed in HEK293 cells.
Topics: Biotransformation; Blotting, Western; Genotype; Glucuronosyltransferase; Glycosylation; HEK293 Cells; Humans; Kinetics; Morphine Derivatives; Mutagenesis, Site-Directed; Mutation; Phenotype; Protein Processing, Post-Translational; Substrate Specificity; Transfection; Zidovudine | 2012 |
A Clinical Metabolite of Azidothymidine Inhibits Experimental Choroidal Neovascularization and Retinal Pigmented Epithelium Degeneration.
Topics: Animals; Blotting, Western; Caspase 1; Choroidal Neovascularization; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Geographic Atrophy; Interleukin-1beta; Intravitreal Injections; Macrophages; Male; Mice; Mice, Inbred C57BL; Microscopy, Confocal; Retinal Pigment Epithelium; Reverse Transcriptase Inhibitors; Zidovudine; Zonula Occludens-1 Protein | 2020 |