3'-azido-2',3'-dideoxyuridine has been researched along with zidovudine in 25 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (36.00) | 18.7374 |
| 1990's | 12 (48.00) | 18.2507 |
| 2000's | 3 (12.00) | 29.6817 |
| 2010's | 1 (4.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Augustyns, K; Balzarini, J; Blaton, N; De Clercq, E; De Ranter, C; Everaert, D; Janssen, G; Jie, L; Peeters, O; Van Aerschot, A | 1 |
| Bhadti, VS; Boudinot, FD; Chu, CK; Doshi, KJ; Etse, JT; Gallo, JM; Schinazi, RF | 1 |
| August, EM; Brankovan, V; Ghazzouli, I; Lin, TS; Prusoff, WH; Shen, ZY; Yang, H | 1 |
| Ahn, MK; Chu, CK; Gu, ZP; Schinazi, RF; Ullas, GV | 1 |
| Baba, M; Balzarini, J; De Clercq, E; Herdewijn, P; Janssen, G; Pauwels, R; Van Aerschot, A | 1 |
| Chu, CK; Guo, JY; Lin, TS; Prusoff, WH; Schinazi, RF; Xiang, JN | 1 |
| Chen, MS; Gao, YS; Ghazzouli, I; Lin, TS; McLaren, C; Prusoff, WH | 1 |
| Gao, YS; Lin, TS; Mancini, WR | 1 |
| Chu, CK; Hong, CI; Kirisits, AJ; Manouilov, KK; Nechaev, A; Vig, R; West, CR | 1 |
| Amblard, F; Asif, G; Bondada, L; Coats, SJ; Detorio, M; Fromentin, E; Mellors, JW; Obikhod, A; Schinazi, RF; Sluis-Cremer, N; Solomon, S; Whitaker, T; Zhang, HW | 1 |
| Chu, CK; Cretton, EM; Goudgaon, NM; Schinazi, RF; Sommadossi, JP; Xie, MY | 1 |
| Bakhmedova, AA; Iartseva, IV; Iurkevich, AM; Mel'nik, SIa; Volosiuk, TP; Zhukova, OS | 1 |
| Broder, S; Kageyama, S; Mitsuya, H; Yarchoan, R | 1 |
| Minick, D; Resetar, A; Spector, T | 1 |
| Boudinot, FD; Chu, CK; Doshi, KJ; Etse, JT; Gallo, JM | 1 |
| Chu, CK; Colby, CB; Schinazi, RF; Sommadossi, JP; Williams, GJ; Zhu, Z | 1 |
| Chu, CK; Eriksson, BF; Schinazi, RF | 1 |
| Broder, S; Cooney, DA; Hao, Z; Hartman, NR; Johns, DG; Mitsuya, H; Perno, CF; Webb, DS; Yarchoan, R | 1 |
| Balzarini, J; de Clercq, E; Herdewijn, P; van Aerschot, A | 1 |
| Boudinot, FD; Chu, CK; Fedorov, II; Manouilov, KK; White, CA | 1 |
| Sawchuk, RJ; Wang, Y; Wong, SL | 1 |
| Danel, K; el-Emam, AA; Larsen, E; Nielsen, C; Pedersen, EB; Vaaben, GB | 1 |
| Bartlett, MG; Chu, CK; Clark, TN; White, CA | 1 |
| Boudinot, FD; Chu, CK; Cooperwood, JS; Kong, L; Oh, CH | 1 |
| Boudinot, FD; Chu, CK; Cooperwood, JS; Huang, SH; Kong, L | 1 |
1 review(s) available for 3'-azido-2',3'-dideoxyuridine and zidovudine
| Article | Year |
|---|---|
Targeted therapy of human immunodeficiency virus-related disease.
Topics: Acquired Immunodeficiency Syndrome; Adenine; Antiviral Agents; CD4 Antigens; Didanosine; Dideoxynucleosides; Dipyridamole; Drug Synergism; Gene Expression Regulation, Viral; Genes, nef; Genes, rev; Genes, tat; HIV; HIV Protease; Interferon Type I; Organophosphonates; RNA-Directed DNA Polymerase; Stavudine; Transcription, Genetic; Zalcitabine; Zidovudine | 1991 |
24 other study(ies) available for 3'-azido-2',3'-dideoxyuridine and zidovudine
| Article | Year |
|---|---|
Synthesis and anti-HIV evaluation of 2',3'-dideoxyribo-5-chloropyrimidine analogues: reduced toxicity of 5-chlorinated 2',3'-dideoxynucleosides.
Topics: Antiviral Agents; Cell Line; Dideoxynucleosides; HIV; Humans; Molecular Conformation; X-Ray Diffraction | 1990 |
Brain targeting of anti-HIV nucleosides: synthesis and in vitro and in vivo studies of dihydropyridine derivatives of 3'-azido-2',3'-dideoxyuridine and 3'-azido-3'-deoxythymidine.
Topics: Animals; Antiviral Agents; Brain; Chemical Phenomena; Chemistry; Dihydropyridines; Half-Life; HIV; Humans; Mice; Molecular Structure; Prodrugs; Zidovudine | 1990 |
Synthesis and antiviral activity of several 2,5'-anhydro analogues of 3'-azido-3'-deoxythymidine, 3'-azido-2',3'-dideoxyuridine, 3'-azido-2',3'-dideoxy-5-halouridines, and 3'-deoxythymidine against human immunodeficiency virus and Rauscher-murine leukemia
Topics: Antiviral Agents; Chemical Phenomena; Chemistry; Deoxyuridine; HIV-1; Rauscher Virus; Thymidine | 1989 |
Structure-activity relationships of pyrimidine nucleosides as antiviral agents for human immunodeficiency virus type 1 in peripheral blood mononuclear cells.
Topics: Antiviral Agents; Cell Division; Chemical Phenomena; Chemistry; HIV-1; Humans; Leukocytes, Mononuclear; Pyrimidine Nucleosides; Structure-Activity Relationship | 1989 |
Synthesis and anti-HIV activity of different sugar-modified pyrimidine and purine nucleosides.
Topics: Animals; Antiviral Agents; Cell Line; Cytopathogenic Effect, Viral; HIV; Magnetic Resonance Spectroscopy; Purine Nucleosides; Pyrimidine Nucleosides; Structure-Activity Relationship; Virus Replication; Zidovudine | 1988 |
Synthesis and antiviral activity of various 3'-azido analogues of pyrimidine deoxyribonucleosides against human immunodeficiency virus (HIV-1, HTLV-III/LAV).
Topics: Antiviral Agents; HIV; Humans; Pyrimidine Nucleosides; Structure-Activity Relationship | 1988 |
Synthesis and antiviral activity of various 3'-azido, 3'-amino, 2',3'-unsaturated, and 2',3'-dideoxy analogues of pyrimidine deoxyribonucleosides against retroviruses.
Topics: Antiviral Agents; Cell Line; HIV; Indicators and Reagents; Magnetic Resonance Spectroscopy; Moloney murine leukemia virus; Pyrimidine Nucleosides; Spectrophotometry; Structure-Activity Relationship | 1987 |
Synthesis and biological activity of various 3'-azido and 3'-amino analogues of 5-substituted pyrimidine deoxyribonucleosides.
Topics: Animals; Antineoplastic Agents; Deoxycytidine; Deoxycytidine Kinase; Deoxyuridine; Leukemia L1210; Mice; Sarcoma 180; Thymidine Kinase | 1983 |
Nucleoside conjugates. 15. Synthesis and biological activity of anti-HIV nucleoside conjugates of ether and thioether phospholipids.
Topics: Animals; Antiviral Agents; Cell Line; Ethers; Female; HIV-1; Humans; In Vitro Techniques; Leukemia L1210; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred DBA; Phospholipids; Tumor Cells, Cultured | 1996 |
Synthesis and evaluation of 3'-azido-2',3'-dideoxypurine nucleosides as inhibitors of human immunodeficiency virus.
Topics: Anti-HIV Agents; Dideoxynucleosides; Glycosylation; HIV Reverse Transcriptase; Humans; Lymphocytes | 2010 |
Catabolic disposition of 3'-azido-2',3'-dideoxyuridine in hepatocytes with evidence of azido reduction being a general catabolic pathway of 3'-azido-2',3'-dideoxynucleosides.
Topics: Animals; Antiviral Agents; Azides; Chromatography, High Pressure Liquid; Deoxyuridine; Dideoxynucleosides; Glucuronates; Hematopoietic Stem Cells; Microsomes, Liver; NADP; Oxidation-Reduction; Rats; Rats, Inbred Strains; Ribonucleosides; Uridine Diphosphate Glucuronic Acid; Zalcitabine; Zidovudine | 1992 |
[Synthesis and cytotoxic properties of anomeric 5-substituted 3'-azido-2',3'-dideoxyuridines].
Topics: Antiviral Agents; Cell Line; Cell Survival; Chromatography, Thin Layer; DNA; Glycosylation; Magnetic Resonance Spectroscopy; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Thymidine; Zidovudine | 1992 |
Glucuronidation of 3'-azido-3'-deoxythymidine catalyzed by human liver UDP-glucuronosyltransferase. Significance of nucleoside hydrophobicity and inhibition by xenobiotics.
Topics: Binding, Competitive; Chloramphenicol; Glucuronosyltransferase; Humans; Kinetics; Microsomes, Liver; Morphine; Substrate Specificity; Xenobiotics; Zidovudine | 1991 |
Hybrid pharmacokinetic models to describe anti-HIV nucleoside brain disposition following parent and prodrug administration in mice.
Topics: Animals; Antiviral Agents; Brain; Dihydropyridines; Female; HIV; Mice; Models, Biological; Nucleosides; Prodrugs; Zidovudine | 1991 |
Cellular metabolism of 3'-azido-2',3'-dideoxyuridine with formation of 5'-O-diphosphohexose derivatives by previously unrecognized metabolic pathways for 2'-deoxyuridine analogs.
Topics: Antiviral Agents; Bone Marrow; Chromatography, High Pressure Liquid; Dideoxynucleotides; HIV; Humans; Leukocytes, Mononuclear; Thymine Nucleotides; Zidovudine | 1990 |
Phosphorylation of 3'-azido-2',3'-dideoxyuridine and preferential inhibition of human and simian immunodeficiency virus reverse transcriptases by its 5'-triphosphate.
Topics: Cells, Cultured; Chromatography, High Pressure Liquid; DNA Polymerase II; HIV; Humans; Kinetics; Phosphorylation; Phosphotransferases; Reverse Transcriptase Inhibitors; Simian Immunodeficiency Virus; Thymidine Kinase; Zidovudine | 1989 |
Replication of human immunodeficiency virus in monocytes. Granulocyte/macrophage colony-stimulating factor (GM-CSF) potentiates viral production yet enhances the antiviral effect mediated by 3'-azido-2'3'-dideoxythymidine (AZT) and other dideoxynucleoside
Topics: Cells, Cultured; Colony-Stimulating Factors; Dideoxynucleosides; Granulocyte-Macrophage Colony-Stimulating Factor; Growth Substances; HIV-1; Humans; Lymphocytes; Monocytes; Stavudine; Virus Replication; Zidovudine | 1989 |
5-Chloro-substituted derivatives of 2', 3'-didehydro-2',3'-dideoxyuridine, 3'-fluoro-2',3'-dideoxyuridine and 3'-azido-2',3'-dideoxyuridine as anti-HIV agents.
Topics: Animals; Antiviral Agents; Cell Line; Dideoxynucleosides; HIV; Humans; Kinetics; Thymidine Kinase; Virus Replication; Zidovudine | 1989 |
Lymphatic distribution of 3'-azido-3'-deoxythymidine and 3'-azido-2',3'-dideoxyuridine in mice.
Topics: Animals; Antiviral Agents; Female; Lymphoid Tissue; Mice; Zidovudine | 1995 |
Microdialysis calibration using retrodialysis and zero-net flux: application to a study of the distribution of zidovudine to rabbit cerebrospinal fluid and thalamus.
Topics: Analysis of Variance; Animals; Antiviral Agents; Calibration; Chromatography, High Pressure Liquid; Male; Microdialysis; Rabbits; Thalamus; Zidovudine | 1993 |
Synthesis of an AZT-HEPT hybrid and homologous AzddU derivatives.
Topics: Antiviral Agents; Thymine; Zidovudine | 1996 |
Determination of 3'-azido-2',3'-dideoxyuridine in maternal plasma, amniotic fluid, fetal and placental tissues by high-performance liquid chromatography.
Topics: Amniotic Fluid; Animals; Antiviral Agents; Chromatography, High Pressure Liquid; Female; Fetus; Molecular Structure; Placenta; Pregnancy; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Zidovudine | 2001 |
Simultaneous determination of 3'-azido-2',3'-dideoxyuridine and novel prodrugs in rat plasma by liquid chromatography.
Topics: Animals; Calibration; Chromatography, High Pressure Liquid; Prodrugs; Rats; Reference Standards; Reverse Transcriptase Inhibitors; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Zidovudine | 2003 |
Pharmacokinetic evaluation of 3'-azido-2', 3'-dideoxyuridine-5'-O-valinate-hydrochloride as a prodrug of the anti-HIV nucleoside 3'-azido-2', 3'-dideoxyuridine.
Topics: Administration, Oral; Animals; Anti-HIV Agents; Biological Availability; Biotransformation; Chromatography, High Pressure Liquid; Esterification; Humans; Pharmacokinetics; Prodrugs; Rats; Rats, Sprague-Dawley; Valine; Zidovudine | 2003 |