3'-amino-2',3'-dideoxythymidine has been researched along with raltitrexed in 1 studies
| Studies (3'-amino-2',3'-dideoxythymidine) | Trials (3'-amino-2',3'-dideoxythymidine) | Recent Studies (post-2010) (3'-amino-2',3'-dideoxythymidine) | Studies (raltitrexed) | Trials (raltitrexed) | Recent Studies (post-2010) (raltitrexed) |
|---|---|---|---|---|---|
| 13 | 0 | 1 | 580 | 143 | 121 |
| Protein | Taxonomy | 3'-amino-2',3'-dideoxythymidine (IC50) | raltitrexed (IC50) |
|---|---|---|---|
| Thymidylate synthase | Escherichia coli | 7.0667 | |
| Dihydrofolate reductase | Homo sapiens (human) | 1.8578 | |
| Thymidylate synthase | Lacticaseibacillus casei | 8.2667 | |
| Thymidylate synthase | Homo sapiens (human) | 1.208 | |
| Thymidylate synthase | Mus musculus (house mouse) | 0.67 | |
| Thymidylate synthase | Escherichia coli K-12 | 2.32 | |
| Dihydrofolate reductase | Escherichia coli K-12 | 2.32 | |
| Folate receptor beta | Homo sapiens (human) | 0.384 | |
| Folate receptor alpha | Homo sapiens (human) | 0.015 | |
| Non-receptor tyrosine-protein kinase TYK2 | Homo sapiens (human) | 0.26 | |
| Reduced folate transporter | Homo sapiens (human) | 0.0063 | |
| Thymidylate synthase | Rattus norvegicus (Norway rat) | 0.9 | |
| Bifunctional dihydrofolate reductase-thymidylate synthase | Toxoplasma gondii | 1.7956 | |
| Proton-coupled folate transporter | Homo sapiens (human) | 0.0995 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gangjee, A; Jain, HD; Kisliuk, RL; Lin, X; McGuire, JJ; Phan, J; Song, X | 1 |
1 other study(ies) available for 3'-amino-2',3'-dideoxythymidine and raltitrexed
| Article | Year |
|---|---|
Dual inhibitors of thymidylate synthase and dihydrofolate reductase as antitumor agents: design, synthesis, and biological evaluation of classical and nonclassical pyrrolo[2,3-d]pyrimidine antifolates(1).
Topics: Antineoplastic Agents; Binding Sites; Cell Line, Tumor; Drug Screening Assays, Antitumor; Escherichia coli; Folic Acid Antagonists; Glutamates; Humans; Models, Molecular; Pyrimidines; Pyrimidinones; Pyrroles; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase; Thermodynamics; Thymidylate Synthase | 2006 |