Page last updated: 2024-09-02

3'-amino-2',3'-dideoxythymidine and carmustine

3'-amino-2',3'-dideoxythymidine has been researched along with carmustine in 1 studies

*Carmustine: A cell-cycle phase nonspecific alkylating antineoplastic agent. It is used in the treatment of brain tumors and various other malignant neoplasms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (From Merck Index, 11th ed) [MeSH]

*Carmustine: A cell-cycle phase nonspecific alkylating antineoplastic agent. It is used in the treatment of brain tumors and various other malignant neoplasms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (From Merck Index, 11th ed) [MeSH]

Compound Research Comparison

Studies
(3'-amino-2',3'-dideoxythymidine)
Trials
(3'-amino-2',3'-dideoxythymidine)
Recent Studies (post-2010)
(3'-amino-2',3'-dideoxythymidine)
Studies
(carmustine)
Trials
(carmustine)
Recent Studies (post-2010) (carmustine)
13014,168686540

Protein Interaction Comparison

ProteinTaxonomy3'-amino-2',3'-dideoxythymidine (IC50)carmustine (IC50)
Glutathione reductase, mitochondrialHomo sapiens (human)8.1

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19901 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brubaker, WF; Lin, TS; Park, S; Prusoff, WH; Wang, ZH1

Other Studies

1 other study(ies) available for 3'-amino-2',3'-dideoxythymidine and carmustine

ArticleYear
Antineoplastic activity of 3'-(chloroethyl)nitrosourea analogues of 2'-deoxyuridine and 2'-deoxy-5-fluorouridine.
    Journal of medicinal chemistry, 1986, Volume: 29, Issue:5

    Topics: Alkylation; Animals; Antineoplastic Agents; Deoxyuridine; Dideoxynucleosides; Female; Floxuridine; Leukemia L1210; Mice; Nitrosourea Compounds; Structure-Activity Relationship

1986