Compounds > 3'-amino-2',3'-dideoxythymidine
Page last updated: 2024-09-02

3'-amino-2',3'-dideoxythymidine and 5'-amino-2',5'-dideoxythymidine

3'-amino-2',3'-dideoxythymidine has been researched along with 5'-amino-2',5'-dideoxythymidine in 7 studies

Compound Research Comparison

Studies
(3'-amino-2',3'-dideoxythymidine)		Trials
(3'-amino-2',3'-dideoxythymidine)		Recent Studies (post-2010)
(3'-amino-2',3'-dideoxythymidine)		Studies
(5'-amino-2',5'-dideoxythymidine)		Trials
(5'-amino-2',5'-dideoxythymidine)		Recent Studies (post-2010) (5'-amino-2',5'-dideoxythymidine)
13013500

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19905 (71.43)18.7374
1990's0 (0.00)18.2507
2000's2 (28.57)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chawla, RR; Hampton, A; Kappler, F2
Lin, TS; Prusoff, WH1
Ahn, MK; Chu, CK; Gu, ZP; Schinazi, RF; Ullas, GV1
Chen, MS; Gao, YS; Ghazzouli, I; Lin, TS; McLaren, C; Prusoff, WH1
Herdewijn, P; Munier-Lehmann, H; Pochet, S; Van Calenbergh, S; Van Rompaey, P; Vanheusden, V1
Harano, A; Hatano, A; Nakagomi, Y; Naramoto, Y; Takigawa, Y; Toda, K; Yamada, H1

Other Studies

7 other study(ies) available for 3'-amino-2',3'-dideoxythymidine and 5'-amino-2',5'-dideoxythymidine

ArticleYear
Design of species- or isozyme-specific enzyme inhibitors. 2. Differences between a bacterial and a mammalian thymidine kinase in the effect of thymidine substituents on affinity for the thymidine site.
    Journal of medicinal chemistry, 1979, Volume: 22, Issue:12

    Topics: Animals; Binding Sites; Cricetinae; Cytoplasm; Escherichia coli; Kinetics; Species Specificity; Structure-Activity Relationship; Thymidine; Thymidine Kinase

1979
Synthesis and biological activity of several amino analogues of thymidine.
    Journal of medicinal chemistry, 1978, Volume: 21, Issue:1

    Topics: Animals; Antineoplastic Agents; Antiviral Agents; Cell Division; Cells, Cultured; Leukemia L1210; Sarcoma 180; Thymidine; Virus Replication

1978
Structure-activity relationships of pyrimidine nucleosides as antiviral agents for human immunodeficiency virus type 1 in peripheral blood mononuclear cells.
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:3

    Topics: Antiviral Agents; Cell Division; Chemical Phenomena; Chemistry; HIV-1; Humans; Leukocytes, Mononuclear; Pyrimidine Nucleosides; Structure-Activity Relationship

1989
Synthesis and antiviral activity of various 3'-azido, 3'-amino, 2',3'-unsaturated, and 2',3'-dideoxy analogues of pyrimidine deoxyribonucleosides against retroviruses.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:2

    Topics: Antiviral Agents; Cell Line; HIV; Indicators and Reagents; Magnetic Resonance Spectroscopy; Moloney murine leukemia virus; Pyrimidine Nucleosides; Spectrophotometry; Structure-Activity Relationship

1987
Species- or isozyme-specific enzyme inhibitors. 5. Differential effects of thymidine substituents on affinity for rat thymidine kinase isozymes.
    Journal of medicinal chemistry, 1982, Volume: 25, Issue:6

    Topics: Animals; Cytoplasm; In Vitro Techniques; Isoenzymes; Kinetics; Mitochondria; Pyrimidine Nucleosides; Rats; Thymidine; Thymidine Kinase; Tissue Distribution

1982
Thymidine and thymidine-5'-O-monophosphate analogues as inhibitors of Mycobacterium tuberculosis thymidylate kinase.
    Bioorganic & medicinal chemistry letters, 2003, Sep-15, Volume: 13, Issue:18

    Topics: Antitubercular Agents; Enzyme Inhibitors; Inhibitory Concentration 50; Kinetics; Mycobacterium tuberculosis; Nucleoside-Phosphate Kinase; Structure-Activity Relationship; Thymidine; Thymine Nucleotides

2003
Kinetic parameters and recognition of thymidine analogues with varying functional groups by thymidine phosphorylase.
    Bioorganic & medicinal chemistry, 2008, Apr-01, Volume: 16, Issue:7

    Topics: Kinetics; Molecular Structure; Structure-Activity Relationship; Substrate Specificity; Thymidine; Thymidine Phosphorylase

2008