Page last updated: 2024-09-03

3',6-dinitroflavone and chrysin

3',6-dinitroflavone has been researched along with chrysin in 5 studies

Compound Research Comparison

Studies
(3',6-dinitroflavone)
Trials
(3',6-dinitroflavone)
Recent Studies (post-2010)
(3',6-dinitroflavone)
Studies
(chrysin)
Trials
(chrysin)
Recent Studies (post-2010) (chrysin)
8019136646

Protein Interaction Comparison

ProteinTaxonomy3',6-dinitroflavone (IC50)chrysin (IC50)
G2/mitotic-specific cyclin-B2Homo sapiens (human)7.1
Cytochrome P450 1A1Homo sapiens (human)0.7215
Cytochrome P450 1A2Homo sapiens (human)0.236
Cyclin-dependent kinase 1Homo sapiens (human)7.1
AromataseHomo sapiens (human)0.667
Cytochrome P450 2C9 Homo sapiens (human)5.225
G2/mitotic-specific cyclin-B1Homo sapiens (human)7.1
Aldo-keto reductase family 1 member B1Homo sapiens (human)8.14
G2/mitotic-specific cyclin-BMarthasterias glacialis (spiny starfish)5.85
Aldo-keto reductase family 1 member B1Bos taurus (cattle)7.79
Carbonyl reductase [NADPH] 1Homo sapiens (human)0.67
Glycogen synthase kinase-3 betaRattus norvegicus (Norway rat)5.85
Casein kinase II subunit alpha'Homo sapiens (human)9
Amine oxidase [flavin-containing] AHomo sapiens (human)1.6
Amine oxidase [flavin-containing] BHomo sapiens (human)1.6
Proteasome subunit beta type-5Homo sapiens (human)5.5
Xanthine dehydrogenase/oxidaseHomo sapiens (human)0.84
Glycogen synthase kinase-3 alphaHomo sapiens (human)7.2
Glycogen synthase kinase-3 betaHomo sapiens (human)7.2
Casein kinase II subunit betaHomo sapiens (human)9
Casein kinase II subunit alphaHomo sapiens (human)9
Xanthine dehydrogenase/oxidaseBos taurus (cattle)1.26
Cyclin-dependent kinase 6Homo sapiens (human)5.88
Cyclin-dependent-like kinase 5 Homo sapiens (human)5.3
Cyclin homologHerpesvirus saimiri (strain 11)5.85
Cyclin-dependent kinase 5 activator 1Homo sapiens (human)5.3
Cytochrome P450 1B1Homo sapiens (human)0.152
Integrase Human immunodeficiency virus 11.4
Casein kinase II subunit alpha 3Homo sapiens (human)9
G2/mitotic-specific cyclin-B3Homo sapiens (human)7.1
3-oxoacyl-acyl-carrier protein reductase Plasmodium falciparum (malaria parasite P. falciparum)10
Cyclin-dependent kinase 1Oryzias latipes (Japanese medaka)5.85
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)2.05

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (60.00)18.2507
2000's2 (40.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dekermendjian, K; Kahnberg, P; Liljefors, T; Nielsen, M; Sterner, O; Witt, MR1
Cao, Y; Chen, K; Gu, J; Huang, X; Ji, R; Jiang, H; Liu, T; Luo, X; Pei, G; Wong, BL; Wong, JT; Xue, H1
Autino, JC; Bennardi, DO; Castro, EA; Duchowicz, PR; Romanelli, GP; Vitale, MG1
Ardenghi, P; Dias, M; Ferreira, MB; Izquierdo, I; Medina, JH; Salgueiro, JB1
Marder, M; Medina, JH; Paladini, AC; Viola, H; Wasowski, C; Wolfman, C1

Other Studies

5 other study(ies) available for 3',6-dinitroflavone and chrysin

ArticleYear
Structure-activity relationships and molecular modeling analysis of flavonoids binding to the benzodiazepine site of the rat brain GABA(A) receptor complex.
    Journal of medicinal chemistry, 1999, Oct-21, Volume: 42, Issue:21

    Topics: Animals; Binding Sites; Brain; Flavonoids; In Vitro Techniques; Male; Models, Molecular; Molecular Conformation; Radioligand Assay; Rats; Rats, Wistar; Receptors, GABA-A; Reproducibility of Results; Structure-Activity Relationship

1999
3D-QSAR model of flavonoids binding at benzodiazepine site in GABAA receptors.
    Journal of medicinal chemistry, 2001, Jun-07, Volume: 44, Issue:12

    Topics: Benzodiazepines; Binding Sites; Calorimetry; Flavonoids; Ligands; Models, Molecular; Molecular Conformation; Mutagenesis, Site-Directed; Protein Structure, Secondary; Protein Subunits; Quantitative Structure-Activity Relationship; Receptors, GABA-A; Recombinant Proteins; Static Electricity

2001
QSAR modeling of the interaction of flavonoids with GABA(A) receptor.
    European journal of medicinal chemistry, 2008, Volume: 43, Issue:8

    Topics: Binding Sites; Flavonoids; Molecular Structure; Protein Binding; Quantitative Structure-Activity Relationship; Receptors, GABA-A

2008
Anxiolytic natural and synthetic flavonoid ligands of the central benzodiazepine receptor have no effect on memory tasks in rats.
    Pharmacology, biochemistry, and behavior, 1997, Volume: 58, Issue:4

    Topics: Animals; Anti-Anxiety Agents; Avoidance Learning; Chamomile; Diazepam; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Ligands; Male; Memory; Oils, Volatile; Plants, Medicinal; Psychomotor Performance; Quercetin; Rats; Rats, Wistar; Reaction Time; Receptors, GABA-A

1997
Flavonoids and the central nervous system: from forgotten factors to potent anxiolytic compounds.
    The Journal of pharmacy and pharmacology, 1999, Volume: 51, Issue:5

    Topics: Anti-Anxiety Agents; Central Nervous System; Chamomile; Flavonoids; Humans; Oils, Volatile; Plants, Medicinal

1999