3',5'-dimethylacetaminophen has been researched along with acetaminophen in 9 studies
*Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage. [MeSH]
*Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage. [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (66.67) | 18.7374 |
| 1990's | 3 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Calder, IC; Fernando, CR; Ham, KN | 1 |
| Bruno, MK; Cohen, SD; Khairallah, EA | 2 |
| Fischer, V; Mason, RP | 2 |
| Harvison, PJ; Moldéus, P; Nelson, SD; Porubek, DJ; Rundgren, M | 1 |
| de Vries, J; Debets, AJ; van de Straat, R; Vermeulen, NP | 1 |
| Kao, KJ; Pizzo, SV; Rauckman, EJ; Rosen, GM; Shorr, RI | 1 |
| Moldéus, P; Nelson, S; Rundgren, M; Weis, M | 1 |
1 review(s) available for 3',5'-dimethylacetaminophen and acetaminophen
| Article | Year |
|---|---|
Free radicals of acetaminophen: their subsequent reactions and toxicological significance.
Topics: Acetaminophen; Animals; Benzoquinones; Chemical and Drug Induced Liver Injury; Chemical Phenomena; Chemistry; Electron Spin Resonance Spectroscopy; Free Radicals; Horseradish Peroxidase; Hydrogen Peroxide; Imines; Lactoperoxidase; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Peroxidases; Superoxides | 1986 |
8 other study(ies) available for 3',5'-dimethylacetaminophen and acetaminophen
| Article | Year |
|---|---|
Studies on the mechanism of toxicity of acetaminophen. Synthesis and reactions of N-acetyl-2,6-dimethyl- and N-acetyl-3,5-dimethyl-p-benzoquinone imines.
Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Chemical Phenomena; Chemistry; Female; Kidney Diseases; Mice; Quinones; Rats | 1980 |
Selective alterations in the patterns of newly synthesized proteins by acetaminophen and its dimethylated analogues in primary cultures of mouse hepatocytes.
Topics: Acetaminophen; Animals; Cells, Cultured; Dactinomycin; Electrophoresis; Enzyme Induction; Heme Oxygenase (Decyclizing); Liver; Male; Mice; Mice, Inbred C57BL; Protein Biosynthesis; Tumor Suppressor Protein p53 | 1992 |
Selective alterations in the profiles of newly synthesized proteins by acetaminophen (APAP) and its dimethylated analogues: relationship to oxidative stress.
Topics: Acetaminophen; Animals; Biotransformation; In Vitro Techniques; Liver; Male; Mice; Mice, Inbred C57BL; Oxidation-Reduction; Protein Biosynthesis; Proteins | 1991 |
Investigation of mechanisms of acetaminophen toxicity in isolated rat hepatocytes with the acetaminophen analogues 3,5-dimethylacetaminophen and 2,6-dimethylacetaminophen.
Topics: Acetaminophen; Animals; Carmustine; Dithiothreitol; Glutathione; Glutathione Reductase; In Vitro Techniques; Kinetics; Lipid Peroxides; Liver; Male; Maleates; Rats; Rats, Inbred Strains | 1987 |
The mechanism of prevention of paracetamol-induced hepatotoxicity by 3,5-dialkyl substitution. The roles of glutathione depletion and oxidative stress.
Topics: Acetaminophen; Animals; Benzoquinones; Carmustine; Chemical and Drug Induced Liver Injury; Glutathione; Imines; Lipid Peroxides; Liver; Liver Diseases; Male; Maleates; Oxidation-Reduction; Quinones; Rats; Rats, Inbred Strains; Structure-Activity Relationship | 1987 |
In vitro effects of acetaminophen and its analogues on human platelet aggregation and thromboxane B2 synthesis.
Topics: Acetaminophen; Arachidonic Acid; Arachidonic Acids; Humans; Platelet Aggregation; Serotonin; Thromboxane B2; Thromboxanes | 1985 |
Stable free radical and benzoquinone imine metabolites of an acetaminophen analogue.
Topics: Acetaminophen; Benzoquinones; Electron Spin Resonance Spectroscopy; Free Radicals; Horseradish Peroxidase; Hydrogen Peroxide; Imines; Indicators and Reagents; Kinetics; Oxidation-Reduction; Peroxidases | 1984 |
Peroxidase-catalyzed oxidation of 3,5-dimethyl acetaminophen causes cell death by selective protein thiol modification in isolated rat hepatocytes.
Topics: Acetaminophen; Animals; Cell Death; Cells, Cultured; Electrophoresis, Polyacrylamide Gel; Glutathione; Liver; Male; Peroxidase; Rats; Rats, Wistar; Sodium Dodecyl Sulfate; Sulfhydryl Compounds; Time Factors | 1996 |