Page last updated: 2024-09-04

3',4'-dihydroxyflavone and flavone

3',4'-dihydroxyflavone has been researched along with flavone in 7 studies

Compound Research Comparison

Studies
(3',4'-dihydroxyflavone)
Trials
(3',4'-dihydroxyflavone)
Recent Studies (post-2010)
(3',4'-dihydroxyflavone)
Studies
(flavone)
Trials
(flavone)
Recent Studies (post-2010) (flavone)
310145661268

Protein Interaction Comparison

ProteinTaxonomy3',4'-dihydroxyflavone (IC50)flavone (IC50)
Poly [ADP-ribose] polymerase tankyrase-1Homo sapiens (human)0.3243
Poly [ADP-ribose] polymerase 1Homo sapiens (human)1.3902
Androgen receptorHomo sapiens (human)5.9
AromataseHomo sapiens (human)6.0027
Dipeptidyl peptidase 4Homo sapiens (human)0.17
Cytochrome P450 1B1Homo sapiens (human)0.6
Poly [ADP-ribose] polymerase tankyrase-2Homo sapiens (human)0.144

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's6 (85.71)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Chan, CB; France, S; He, K; Huang, J; Jang, SW; Jia, Y; Liu, X; Luo, HR; Phun, LH; Pradoldej, S; Xiao, G; Ye, K1
Kogami, Y; Matsuda, H; Nakamura, S; Sugiyama, T; Ueno, T; Yoshikawa, M1
Fallarero, A; Haikarainen, T; Lehtiö, L; Narwal, M; Vuorela, PM1
Fernandes, E; Freitas, M; Porto, G; Ribeiro, D; Silva, AM; Tomé, SM1
Cabrita, EJ; Fernandes, E; Freitas, M; Marques, MM; Porto, G; Ribeiro, D; Silva, AM; Tomé, SM1
An, JY; Kim, NJ; Kim, SW; Lee, HH; Lee, J; Lee, KT; Park, JS; Shin, JS; Son, SH; Yoo, HS; Yu, J1
Fernandes, E; Fernandes, PA; Freitas, M; Oliveira, A; Proença, C; Ramos, MJ; Ribeiro, D; Silva, AMS; Sousa, JLC1

Other Studies

7 other study(ies) available for 3',4'-dihydroxyflavone and flavone

ArticleYear
A synthetic 7,8-dihydroxyflavone derivative promotes neurogenesis and exhibits potent antidepressant effect.
    Journal of medicinal chemistry, 2010, Dec-09, Volume: 53, Issue:23

    Topics: Animals; Antidepressive Agents; Apoptosis; Flavones; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Inbred C57BL; Neurogenesis; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship

2010
Structural requirements of flavonoids for the adipogenesis of 3T3-L1 cells.
    Bioorganic & medicinal chemistry, 2011, May-01, Volume: 19, Issue:9

    Topics: 3T3-L1 Cells; Adipogenesis; Animals; CCAAT-Enhancer-Binding Protein-alpha; CCAAT-Enhancer-Binding Protein-beta; CCAAT-Enhancer-Binding Protein-delta; Deoxyglucose; Fatty Acid-Binding Proteins; Flavonoids; Glucose Transporter Type 4; Mice; PPAR gamma; Structure-Activity Relationship

2011
Screening and structural analysis of flavones inhibiting tankyrases.
    Journal of medicinal chemistry, 2013, May-09, Volume: 56, Issue:9

    Topics: Amino Acid Sequence; Drug Evaluation, Preclinical; Enzyme Inhibitors; Flavones; Humans; Models, Molecular; Molecular Sequence Data; Protein Conformation; Small Molecule Libraries; Substrate Specificity; Tankyrases

2013
Modulation of human neutrophils' oxidative burst by flavonoids.
    European journal of medicinal chemistry, 2013, Volume: 67

    Topics: Flavonoids; Humans; Luminescent Measurements; Molecular Structure; Neutrophils; Oxidation-Reduction

2013
Inhibition of LOX by flavonoids: a structure-activity relationship study.
    European journal of medicinal chemistry, 2014, Jan-24, Volume: 72

    Topics: Dose-Response Relationship, Drug; Flavonoids; Glycine max; Humans; Leukotriene B4; Lipoxygenase; Molecular Structure; Neutrophils; Structure-Activity Relationship

2014
Identification and structure activity relationship of novel flavone derivatives that inhibit the production of nitric oxide and PGE
    Bioorganic & medicinal chemistry letters, 2017, 06-01, Volume: 27, Issue:11

    Topics: Animals; Anti-Inflammatory Agents; Dinoprostone; Flavones; Lipopolysaccharides; Macrophages; Mice; Nitric Oxide; RAW 264.7 Cells; Structure-Activity Relationship

2017
Structural Specificity of Flavonoids in the Inhibition of Human Fructose 1,6-Bisphosphatase.
    Journal of natural products, 2020, 05-22, Volume: 83, Issue:5

    Topics: Drug Design; Enzyme Inhibitors; Flavonoids; Fructose; Fructose-Bisphosphatase; Humans; Hypoglycemic Agents; Liver; Molecular Structure

2020