Page last updated: 2024-09-04

3',4'-dihydroxyflavone and diosmetin

3',4'-dihydroxyflavone has been researched along with diosmetin in 6 studies

Compound Research Comparison

Studies
(3',4'-dihydroxyflavone)
Trials
(3',4'-dihydroxyflavone)
Recent Studies (post-2010)
(3',4'-dihydroxyflavone)
Studies
(diosmetin)
Trials
(diosmetin)
Recent Studies (post-2010) (diosmetin)
310141870140

Protein Interaction Comparison

ProteinTaxonomy3',4'-dihydroxyflavone (IC50)diosmetin (IC50)
Cytochrome P450 1A1Homo sapiens (human)0.14
Cytochrome P450 1A2Homo sapiens (human)2.437
Multidrug resistance-associated protein 1 Homo sapiens (human)3
Cytochrome P450 1B1Homo sapiens (human)0.029
Inositol polyphosphate multikinaseHomo sapiens (human)7.2
Aurora kinase BHomo sapiens (human)3.86
Inositol hexakisphosphate kinase 2Homo sapiens (human)0.9

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's4 (66.67)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Gavande, N; Hanrahan, JR; Hibbs, DE; Kim, MS; Matin, A; Roubin, RH; Salam, NK; Yang, NX1
Doddareddy, MR; Gavande, N; Groundwater, PW; Hibbs, DE; Matin, A; Nammi, S; Roubin, RH1
Fernandes, E; Freitas, M; Porto, G; Ribeiro, D; Silva, AM; Tomé, SM1
Cabrita, EJ; Fernandes, E; Freitas, M; Marques, MM; Porto, G; Ribeiro, D; Silva, AM; Tomé, SM1
Chakraborty, A; Chakraborty, M; Frye, SV; Gu, C; Pearce, KH; Puhl-Rubio, AC; Shears, SB; Stashko, MA; Wang, H; Wang, X1
Albiñana, CB; Brynda, J; Fanfrlík, J; Flieger, M; Hodek, J; Karlukova, E; Konvalinka, J; Kožíšek, M; Machara, A; Majer, P; Radilová, K; Weber, J; Zima, V1

Other Studies

6 other study(ies) available for 3',4'-dihydroxyflavone and diosmetin

ArticleYear
7-Hydroxy-benzopyran-4-one derivatives: a novel pharmacophore of peroxisome proliferator-activated receptor alpha and -gamma (PPARalpha and gamma) dual agonists.
    Journal of medicinal chemistry, 2009, Nov-12, Volume: 52, Issue:21

    Topics: Benzopyrans; Cell Line; Humans; PPAR alpha; PPAR gamma; Structure-Activity Relationship

2009
The discovery of novel isoflavone pan peroxisome proliferator-activated receptor agonists.
    Bioorganic & medicinal chemistry, 2013, Feb-01, Volume: 21, Issue:3

    Topics: Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Discovery; HEK293 Cells; Humans; Isoflavones; Models, Molecular; Molecular Structure; Peroxisome Proliferator-Activated Receptors; Structure-Activity Relationship

2013
Modulation of human neutrophils' oxidative burst by flavonoids.
    European journal of medicinal chemistry, 2013, Volume: 67

    Topics: Flavonoids; Humans; Luminescent Measurements; Molecular Structure; Neutrophils; Oxidation-Reduction

2013
Inhibition of LOX by flavonoids: a structure-activity relationship study.
    European journal of medicinal chemistry, 2014, Jan-24, Volume: 72

    Topics: Dose-Response Relationship, Drug; Flavonoids; Glycine max; Humans; Leukotriene B4; Lipoxygenase; Molecular Structure; Neutrophils; Structure-Activity Relationship

2014
Inhibition of Inositol Polyphosphate Kinases by Quercetin and Related Flavonoids: A Structure-Activity Analysis.
    Journal of medicinal chemistry, 2019, 02-14, Volume: 62, Issue:3

    Topics: Binding Sites; Crystallography, X-Ray; HCT116 Cells; Humans; Inositol Phosphates; Molecular Structure; Phosphotransferases (Alcohol Group Acceptor); Phosphotransferases (Phosphate Group Acceptor); Protein Binding; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Quercetin; Structure-Activity Relationship

2019
Unraveling the anti-influenza effect of flavonoids: Experimental validation of luteolin and its congeners as potent influenza endonuclease inhibitors.
    European journal of medicinal chemistry, 2020, Dec-15, Volume: 208

    Topics: Antiviral Agents; Crystallography, X-Ray; Drug Evaluation, Preclinical; Endonucleases; Enzyme Assays; Enzyme Inhibitors; Flavonoids; Influenza A virus; Microbial Sensitivity Tests; Molecular Structure; Protein Binding; Protein Domains; RNA-Dependent RNA Polymerase; Structure-Activity Relationship; Viral Proteins

2020