3',4',7-trimethoxyflavone has been researched along with topotecan in 1 studies
| Studies (3',4',7-trimethoxyflavone) | Trials (3',4',7-trimethoxyflavone) | Recent Studies (post-2010) (3',4',7-trimethoxyflavone) | Studies (topotecan) | Trials (topotecan) | Recent Studies (post-2010) (topotecan) |
|---|---|---|---|---|---|
| 7 | 0 | 4 | 2,392 | 626 | 792 |
| Protein | Taxonomy | 3',4',7-trimethoxyflavone (IC50) | topotecan (IC50) |
|---|---|---|---|
| Cytochrome P450 3A4 | Homo sapiens (human) | 1.5211 | |
| DNA topoisomerase 1 | Homo sapiens (human) | 0.8525 | |
| DNA topoisomerase 2-alpha | Homo sapiens (human) | 0.605 | |
| DNA topoisomerase 2-beta | Homo sapiens (human) | 0.605 | |
| Hypoxia-inducible factor 1-alpha | Homo sapiens (human) | 0.06 | |
| Multidrug and toxin extrusion protein 2 | Homo sapiens (human) | 8.6 | |
| Multidrug and toxin extrusion protein 1 | Homo sapiens (human) | 1.3 | |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | Homo sapiens (human) | 0.17 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hasegawa, H; Katayama, K; Masuyama, K; Mitsuhashi, J; Sugimoto, Y; Yoshioka, S | 1 |
1 other study(ies) available for 3',4',7-trimethoxyflavone and topotecan
| Article | Year |
|---|---|
Flavonoids inhibit breast cancer resistance protein-mediated drug resistance: transporter specificity and structure-activity relationship.
Topics: Antineoplastic Agents, Hormonal; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Flavones; Flavonoids; Humans; Inhibitory Concentration 50; K562 Cells; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Structure-Activity Relationship; Topotecan | 2007 |