Page last updated: 2024-09-03

3-(trifluoromethyl)-3-(3-iodophenyl)diazirine and phencyclidine

3-(trifluoromethyl)-3-(3-iodophenyl)diazirine has been researched along with phencyclidine in 4 studies

Compound Research Comparison

Studies
(3-(trifluoromethyl)-3-(3-iodophenyl)diazirine)
Trials
(3-(trifluoromethyl)-3-(3-iodophenyl)diazirine)
Recent Studies (post-2010)
(3-(trifluoromethyl)-3-(3-iodophenyl)diazirine)
Studies
(phencyclidine)
Trials
(phencyclidine)
Recent Studies (post-2010) (phencyclidine)
760028,2943877,796

Protein Interaction Comparison

ProteinTaxonomy3-(trifluoromethyl)-3-(3-iodophenyl)diazirine (IC50)phencyclidine (IC50)
Glutamate receptor ionotropic, NMDA 1 Rattus norvegicus (Norway rat)0.1299
Lysosomal Pro-X carboxypeptidaseHomo sapiens (human)0.091
Glutamate receptor ionotropic, NMDA 2A Rattus norvegicus (Norway rat)0.1299
Glutamate receptor ionotropic, NMDA 2BRattus norvegicus (Norway rat)0.1299
Glutamate receptor ionotropic, NMDA 2CRattus norvegicus (Norway rat)0.1299
Glutamate receptor ionotropic, NMDA 1Homo sapiens (human)0.5563
Glutamate receptor ionotropic, NMDA 2AHomo sapiens (human)0.205
Glutamate receptor ionotropic, NMDA 2BHomo sapiens (human)1.2589
Glutamate receptor ionotropic, NMDA 2DRattus norvegicus (Norway rat)0.1299
Glutamate receptor ionotropic, NMDA 3BRattus norvegicus (Norway rat)0.1299
Sigma non-opioid intracellular receptor 1Rattus norvegicus (Norway rat)0.53
Glutamate receptor ionotropic, NMDA 3ARattus norvegicus (Norway rat)0.1299

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's1 (25.00)18.2507
2000's2 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cohen, JB; Cohen, SG; Howard, S; White, BH1
McCarthy, MP; Stroud, RM1
Baenziger, JE; Blanton, MP; Ryan, SE1
Blanton, MP; Chiara, DC; Cohen, JB; Hamouda, AK1

Other Studies

4 other study(ies) available for 3-(trifluoromethyl)-3-(3-iodophenyl)diazirine and phencyclidine

ArticleYear
The hydrophobic photoreagent 3-(trifluoromethyl)-3-m-([125I] iodophenyl) diazirine is a novel noncompetitive antagonist of the nicotinic acetylcholine receptor.
    The Journal of biological chemistry, 1991, Nov-15, Volume: 266, Issue:32

    Topics: Affinity Labels; Amphibian Venoms; Animals; Azirines; Carbachol; Cell Membrane; Electric Organ; Iodine Radioisotopes; Kinetics; Macromolecular Substances; Nicotinic Antagonists; Phencyclidine; Receptors, Nicotinic; Sodium; Torpedo

1991
Changes in conformation upon agonist binding, and nonequivalent labeling, of the membrane-spanning regions of the nicotinic acetylcholine receptor subunits.
    The Journal of biological chemistry, 1989, Jun-25, Volume: 264, Issue:18

    Topics: Animals; Azirines; Binding, Competitive; Bungarotoxins; Carbachol; Cell Membrane; Kinetics; Macromolecular Substances; Phencyclidine; Photochemistry; Protein Binding; Protein Conformation; Receptors, Nicotinic

1989
A conformational intermediate between the resting and desensitized states of the nicotinic acetylcholine receptor.
    The Journal of biological chemistry, 2001, Feb-16, Volume: 276, Issue:7

    Topics: Animals; Azirines; Dose-Response Relationship, Drug; Models, Biological; Nicotinic Antagonists; Phencyclidine; Photoaffinity Labels; Proadifen; Protein Conformation; Receptors, Nicotinic; Spectroscopy, Fourier Transform Infrared

2001
Probing the structure of the affinity-purified and lipid-reconstituted torpedo nicotinic acetylcholine receptor.
    Biochemistry, 2008, Dec-02, Volume: 47, Issue:48

    Topics: Affinity Labels; Animals; Azirines; Binding Sites; Cholates; Iodine Radioisotopes; Ion Channels; Lipid Metabolism; Models, Molecular; Nicotinic Antagonists; Phencyclidine; Protein Structure, Secondary; Protein Structure, Tertiary; Receptors, Nicotinic; Solubility; Spectroscopy, Fourier Transform Infrared; Staining and Labeling; Substrate Specificity; Torpedo

2008