Page last updated: 2024-09-03

3-(trifluoromethyl)-3-(3-iodophenyl)diazirine and carbachol

3-(trifluoromethyl)-3-(3-iodophenyl)diazirine has been researched along with carbachol in 5 studies

Compound Research Comparison

Studies
(3-(trifluoromethyl)-3-(3-iodophenyl)diazirine)
Trials
(3-(trifluoromethyl)-3-(3-iodophenyl)diazirine)
Recent Studies (post-2010)
(3-(trifluoromethyl)-3-(3-iodophenyl)diazirine)
Studies
(carbachol)
Trials
(carbachol)
Recent Studies (post-2010) (carbachol)
760013,91881968

Protein Interaction Comparison

ProteinTaxonomy3-(trifluoromethyl)-3-(3-iodophenyl)diazirine (IC50)carbachol (IC50)
Muscarinic acetylcholine receptor M2Homo sapiens (human)0.7849
Muscarinic acetylcholine receptor M4Homo sapiens (human)2.0626
Muscarinic acetylcholine receptor M1Rattus norvegicus (Norway rat)3.4134
Muscarinic acetylcholine receptor M3Rattus norvegicus (Norway rat)2.9961
Muscarinic acetylcholine receptor M4Rattus norvegicus (Norway rat)2.535
Muscarinic acetylcholine receptor M5Rattus norvegicus (Norway rat)2.9961
Muscarinic acetylcholine receptor M2Rattus norvegicus (Norway rat)2.6638
Muscarinic acetylcholine receptor M1Homo sapiens (human)4.849
Muscarinic acetylcholine receptor M3Homo sapiens (human)4.99

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's4 (80.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cohen, JB; White, BH1
Cohen, JB; Cohen, SG; Howard, S; White, BH1
McCarthy, MP; Stroud, RM1
Blanton, MP; Cohen, JB1
Butler, DH; Lasalde, JA; McNamee, MG; Tamamizu, S1

Other Studies

5 other study(ies) available for 3-(trifluoromethyl)-3-(3-iodophenyl)diazirine and carbachol

ArticleYear
Agonist-induced changes in the structure of the acetylcholine receptor M2 regions revealed by photoincorporation of an uncharged nicotinic noncompetitive antagonist.
    The Journal of biological chemistry, 1992, Aug-05, Volume: 267, Issue:22

    Topics: Amino Acid Sequence; Animals; Azirines; Binding Sites; Carbachol; Cell Membrane; Cyanogen Bromide; Electric Organ; Iodine Radioisotopes; Macromolecular Substances; Models, Structural; Molecular Sequence Data; Peptide Fragments; Protein Conformation; Receptors, Nicotinic; Torpedo; Trypsin

1992
The hydrophobic photoreagent 3-(trifluoromethyl)-3-m-([125I] iodophenyl) diazirine is a novel noncompetitive antagonist of the nicotinic acetylcholine receptor.
    The Journal of biological chemistry, 1991, Nov-15, Volume: 266, Issue:32

    Topics: Affinity Labels; Amphibian Venoms; Animals; Azirines; Carbachol; Cell Membrane; Electric Organ; Iodine Radioisotopes; Kinetics; Macromolecular Substances; Nicotinic Antagonists; Phencyclidine; Receptors, Nicotinic; Sodium; Torpedo

1991
Changes in conformation upon agonist binding, and nonequivalent labeling, of the membrane-spanning regions of the nicotinic acetylcholine receptor subunits.
    The Journal of biological chemistry, 1989, Jun-25, Volume: 264, Issue:18

    Topics: Animals; Azirines; Binding, Competitive; Bungarotoxins; Carbachol; Cell Membrane; Kinetics; Macromolecular Substances; Phencyclidine; Photochemistry; Protein Binding; Protein Conformation; Receptors, Nicotinic

1989
Identifying the lipid-protein interface of the Torpedo nicotinic acetylcholine receptor: secondary structure implications.
    Biochemistry, 1994, Mar-15, Volume: 33, Issue:10

    Topics: Amino Acid Sequence; Animals; Azirines; Binding Sites; Carbachol; Cell Membrane; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Electric Organ; Electrophoresis, Polyacrylamide Gel; Lipid Metabolism; Models, Molecular; Molecular Sequence Data; Peptide Fragments; Peptide Mapping; Protein Structure, Secondary; Receptors, Nicotinic; Torpedo

1994
Effects of antibody binding on structural transitions of the nicotinic acetylcholine receptor.
    Biochemistry, 1996, Sep-10, Volume: 35, Issue:36

    Topics: Affinity Labels; Animals; Antibodies, Monoclonal; Antigen-Antibody Complex; Azirines; Bungarotoxins; Carbachol; Cross-Linking Reagents; Curare; Electrophoresis, Polyacrylamide Gel; Gene Expression; Immunoglobulin Fab Fragments; Oocytes; Patch-Clamp Techniques; Receptors, Nicotinic; Torpedo; Xenopus laevis

1996