3-(piperidine-1-yl)propyl 4-amino-5-chloro-2-methoxybenzoate hydrochloride has been researched along with cisapride in 3 studies
| Studies (3-(piperidine-1-yl)propyl 4-amino-5-chloro-2-methoxybenzoate hydrochloride) | Trials (3-(piperidine-1-yl)propyl 4-amino-5-chloro-2-methoxybenzoate hydrochloride) | Recent Studies (post-2010) (3-(piperidine-1-yl)propyl 4-amino-5-chloro-2-methoxybenzoate hydrochloride) | Studies (cisapride) | Trials (cisapride) | Recent Studies (post-2010) (cisapride) |
|---|---|---|---|---|---|
| 10 | 0 | 4 | 1,554 | 390 | 110 |
| Protein | Taxonomy | 3-(piperidine-1-yl)propyl 4-amino-5-chloro-2-methoxybenzoate hydrochloride (IC50) | cisapride (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | 0.767 | |
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Homo sapiens (human) | 3.37 | |
| Cytochrome P450 3A4 | Homo sapiens (human) | 0.3 | |
| 5-hydroxytryptamine receptor 2C | Rattus norvegicus (Norway rat) | 0.0098 | |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 3.5923 | |
| Cytochrome P450 2D6 | Homo sapiens (human) | 0.07 | |
| Angiotensin-converting enzyme | Oryctolagus cuniculus (rabbit) | 0.1701 | |
| D(2) dopamine receptor | Homo sapiens (human) | 0.35 | |
| Dipeptidyl peptidase 4 | Rattus norvegicus (Norway rat) | 2.69 | |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | 0.0098 | |
| Insulin receptor | Rattus norvegicus (Norway rat) | 3.37 | |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | 2.29 | |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | 3.3827 | |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | 3.26 | |
| D | Rattus norvegicus (Norway rat) | 0.0065 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 3.6495 | |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0065 | |
| D(1A) dopamine receptor | Homo sapiens (human) | 1.7 | |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0065 | |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0065 | |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | 2.29 | |
| Sodium-dependent dopamine transporter | Rattus norvegicus (Norway rat) | 0.0065 | |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | 0.083 | |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 0.0054 | |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | 0.2597 | |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | 3.6495 | |
| 5-hydroxytryptamine receptor 1D | Rattus norvegicus (Norway rat) | 4.47 | |
| 5-hydroxytryptamine receptor 1F | Rattus norvegicus (Norway rat) | 4.47 | |
| 5-hydroxytryptamine receptor 2B | Rattus norvegicus (Norway rat) | 0.0098 | |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | 0.384 | |
| Alpha-1A adrenergic receptor | Homo sapiens (human) | 0.03 | |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | 3.37 | |
| Alpha-1B adrenergic receptor | Homo sapiens (human) | 0.03 | |
| D(3) dopamine receptor | Homo sapiens (human) | 0.144 | |
| 5-hydroxytryptamine receptor 3A | Rattus norvegicus (Norway rat) | 0.9 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 0.0407 | |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | 2.29 | |
| D(2) dopamine receptor | Rattus norvegicus (Norway rat) | 0.535 | |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 0.2536 | |
| Nuclear receptor subfamily 3 group C member 3 | Bos taurus (cattle) | 0.1701 | |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | 0.994 | |
| 5-hydroxytryptamine receptor 3B | Rattus norvegicus (Norway rat) | 0.9 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Anzini, M; Campiani, G; Cappelli, A; Caselli, G; Castriconi, F; Costa, T; De Rienzo, F; Giuliani, G; Lanza, M; Mennuni, L; Menziani, MC; Molinari, P; Paolino, M; Sabatini, C; Sbraccia, M | 1 |
| Bloomquist, W; Calligaro, DA; Cohen, I; Cohen, ML; Schaus, JM; Susemichel, AD; Thompson, DC | 1 |
| Ajdary, S; Ataee, R; Rezayat, M; Shahriari, S; Shokrgozar, MA; Zarrindast, MR | 1 |
3 other study(ies) available for 3-(piperidine-1-yl)propyl 4-amino-5-chloro-2-methoxybenzoate hydrochloride and cisapride
| Article | Year |
|---|---|
Synthesis and structure-activity relationship studies in serotonin 5-HT4 receptor ligands based on a benzo[de][2,6]naphthridine scaffold.
Topics: Animals; Crystallography, X-Ray; Dose-Response Relationship, Drug; Guinea Pigs; Ligands; Male; Models, Molecular; Molecular Structure; Naphthyridines; Receptors, Serotonin, 5-HT4; Serotonin 5-HT4 Receptor Agonists; Structure-Activity Relationship | 2014 |
LY353433, a potent, orally effective, long-acting 5-HT(4) receptor antagonist: comparison to cisapride and RS23597-190.
Topics: Adamantane; Administration, Oral; Aminobenzoates; Animals; Cisapride; Esophagus; Female; In Vitro Techniques; Indazoles; Male; Muscle Relaxation; para-Aminobenzoates; Piperidines; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Rats, Wistar; Serotonin Antagonists | 1996 |
Study of 5HT3 and HT4 receptor expression in HT29 cell line and human colon adenocarcinoma tissues.
Topics: Adenocarcinoma; Aminobenzoates; Biguanides; Blotting, Western; Bridged Bicyclo Compounds, Heterocyclic; Cell Proliferation; Cisapride; Colonic Neoplasms; HT29 Cells; Humans; Oxazines; para-Aminobenzoates; Piperidines; Receptors, Serotonin, 5-HT3; Receptors, Serotonin, 5-HT4; Serotonin 5-HT3 Receptor Agonists; Serotonin 5-HT3 Receptor Antagonists; Serotonin 5-HT4 Receptor Agonists; Serotonin 5-HT4 Receptor Antagonists | 2010 |