3-(glutathion-s-yl)acetaminophen has been researched along with acetaminophen in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (41.18) | 18.7374 |
| 1990's | 3 (17.65) | 18.2507 |
| 2000's | 4 (23.53) | 29.6817 |
| 2010's | 3 (17.65) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kamiyama, T; Liu, J; Marumo, F; Miyakawa, H; Sato, C; Shigesawa, T; Tajiri, K | 1 |
| Liu, J; Marumo, F; Sato, C | 1 |
| Marumo, F; Sato, C | 1 |
| Gregus, Z; Klaassen, CD; Madhu, C | 1 |
| Izumi, N; Sato, C | 1 |
| Coles, B; Hinson, JA; Ketterer, B; Nelson, SD; Wardman, P; Wilson, I | 1 |
| Baillie, TA; Hoffmann, KJ | 1 |
| Hinson, JA; Miller, DW; Potter, DW | 1 |
| Hammarström, S; Ormstad, K; Orning, L; Uehara, N | 1 |
| Klaassen, CD; Siegers, CP | 1 |
| Burcham, PC; Calder, IC; Nicholls-Grzemski, FA; Priestly, BG | 1 |
| Du, A; Espina, R; Gan, LS; Graciani, N; Mutlib, AE; Shockcor, J | 1 |
| Chung, JH; Jung, DW; Kim, SJ; Kim, YC; Lee, JY; Moon, CK; Park, HA | 1 |
| Aleksunes, LM; Csanaky, IL; Klaassen, CD; Reisman, SA | 1 |
| Červinková, Z; Česla, P; Kučera, O; Nýdlová, E; Pařík, P; Roušar, T; Staňková, P | 1 |
| Cesla, P; Jankovičová, B; Nýdlová, E; Roušar, T; Ventura, K; Vrbová, M | 1 |
| Hu, W; Jiang, X; Li, R; Wang, L; Zeng, J; Zhang, X | 1 |
17 other study(ies) available for 3-(glutathion-s-yl)acetaminophen and acetaminophen
| Article | Year |
|---|---|
Effects of caffeine on paracetamol activation in rat and mouse liver microsomes.
Topics: Acetaminophen; Animals; Caffeine; Inactivation, Metabolic; Male; Mice; Microsomes, Liver; NADP; Rats; Rats, Inbred Strains | 1992 |
Characterization of the acetaminophen-glutathione conjugation reaction by liver microsomes: species difference in the effects of acetone.
Topics: Acetaminophen; Acetone; Animals; Glutathione; Kinetics; Male; Mice; Microsomes, Liver; Rabbits; Rats; Rats, Inbred Strains; Species Specificity; Temperature | 1991 |
Synergistic effect of NADH on NADPH-dependent acetaminophen activation in liver microsomes and its inhibition by cyanide.
Topics: Acetaminophen; Animals; Kinetics; Male; Mice; Mice, Inbred C57BL; Microsomes, Liver; NAD; NADP; Rats; Rats, Inbred Strains; Sodium Cyanide | 1991 |
Biliary excretion of acetaminophen-glutathione as an index of toxic activation of acetaminophen: effect of chemicals that alter acetaminophen hepatotoxicity.
Topics: Acetaminophen; Animals; Antioxidants; Bile; Biotransformation; Cricetinae; Cysteamine; Liver; Male; Mesocricetus; Methylcholanthrene; Phenobarbital; Prostaglandin Antagonists | 1989 |
Mechanism of increased hepatotoxicity of acetaminophen by the simultaneous administration of caffeine in the rat.
Topics: Acetaminophen; Animals; Biotransformation; Caffeine; Drug Interactions; Glutathione; In Vitro Techniques; Liver; Male; Microsomes, Liver; Rats; Rats, Inbred Strains | 1989 |
The spontaneous and enzymatic reaction of N-acetyl-p-benzoquinonimine with glutathione: a stopped-flow kinetic study.
Topics: Acetaminophen; Animals; Benzoquinones; Glutathione; Glutathione Disulfide; Glutathione Transferase; Humans; Imines; Isoenzymes; Kinetics; Rats; Spectrophotometry, Ultraviolet; Structure-Activity Relationship | 1988 |
The use of alkoxycarbonyl derivatives for the mass spectral analysis of drug-thioether metabolites. Studies with the cysteine, mercapturic acid and glutathione conjugates of acetaminophen.
Topics: Acetaminophen; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Cysteine; Esters; Gas Chromatography-Mass Spectrometry; Indicators and Reagents; Mass Spectrometry | 1988 |
Horseradish peroxidase-catalyzed oxidation of acetaminophen to intermediates that form polymers or conjugate with glutathione.
Topics: Acetaminophen; Benzoquinones; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Free Radicals; Glutathione; Horseradish Peroxidase; Imines; Magnetic Resonance Spectroscopy; Oxidation-Reduction; Peroxidases; Polymers | 1986 |
Characteristics of the uptake of cysteine-containing leukotrienes by isolated hepatocytes.
Topics: Acetaminophen; Animals; Biological Transport; Cysteine; Glutathione; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Leukotriene B4; Leukotriene E4; Liver; Male; Rats; Rats, Inbred Strains; SRS-A; Temperature; Tritium | 1983 |
Biliary excretion of acetaminophen in ureter-ligated rats.
Topics: Acetaminophen; Animals; Bile; Kidney Failure, Chronic; Ligation; Male; Rats; Rats, Inbred Strains; Sulfuric Acids; Ureter | 1984 |
Clofibrate-induced in vitro hepatoprotection against acetaminophen is not due to altered glutathione homeostasis.
Topics: Acetaminophen; Animals; Antidotes; Cell Survival; Cells, Cultured; Chemical and Drug Induced Liver Injury; Clofibrate; Dose-Response Relationship, Drug; Drug Antagonism; Glutathione; Homeostasis; L-Iditol 2-Dehydrogenase; L-Lactate Dehydrogenase; Liver; Male; Maleates; Mice; Peroxisome Proliferators | 2000 |
Disposition of glutathione conjugates in rats by a novel glutamic acid pathway: characterization of unique peptide conjugates by liquid chromatography/mass spectrometry and liquid chromatography/NMR.
Topics: Acetaminophen; Animals; Bile; Chromatography, Liquid; Dipeptides; Glutamic Acid; Glutathione; Kidney; Liver; Male; Mass Spectrometry; Nuclear Magnetic Resonance, Biomolecular; Oligopeptides; Rats; Rats, Sprague-Dawley; Subcellular Fractions | 2000 |
Effect of taurine on biliary excretion and metabolism of acetaminophen in male hamsters.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Bile; Cricetinae; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Male; Mesocricetus; Taurine; Time Factors | 2004 |
Altered disposition of acetaminophen in Nrf2-null and Keap1-knockdown mice.
Topics: Acetaminophen; Adaptor Proteins, Signal Transducing; Animals; Bile; Biotransformation; Carrier Proteins; Cytoskeletal Proteins; Gene Knockdown Techniques; Guinea Pigs; Kelch-Like ECH-Associated Protein 1; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microscopy, Fluorescence; Microsomes, Liver; NAD(P)H Dehydrogenase (Quinone); NADPH Dehydrogenase; NF-E2-Related Factor 2 | 2009 |
Purified acetaminophen-glutathione conjugate is able to induce oxidative stress in rat liver mitochondria.
Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Dose-Response Relationship, Drug; Glutamic Acid; Liver; Malates; Male; Mitochondria, Liver; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species | 2012 |
Comparison of inhibitory effects between acetaminophen-glutathione conjugate and reduced glutathione in human glutathione reductase.
Topics: Acetaminophen; Dose-Response Relationship, Drug; Erythrocytes; Glutathione; Glutathione Disulfide; Glutathione Reductase; Humans; Recombinant Proteins | 2014 |
A reliable LC-MS/MS method for the quantification of N-acetyl-p-benzoquinoneimine, acetaminophen glutathione and acetaminophen glucuronide in mouse plasma, liver and kidney: Method validation and application to a pharmacokinetic study.
Topics: Acetaminophen; Animals; Benzoquinones; Chromatography, Liquid; Imines; Limit of Detection; Linear Models; Mice; Mice, Inbred ICR; Reproducibility of Results; Tandem Mass Spectrometry; Tissue Distribution | 2018 |