Page last updated: 2024-09-04

3-(difluoromethyl)-1-(4-methoxyphenyl)-5-(4-(methylsulfinyl)phenyl)pyrazole and prazosin

3-(difluoromethyl)-1-(4-methoxyphenyl)-5-(4-(methylsulfinyl)phenyl)pyrazole has been researched along with prazosin in 1 studies

Compound Research Comparison

Studies
(3-(difluoromethyl)-1-(4-methoxyphenyl)-5-(4-(methylsulfinyl)phenyl)pyrazole)
Trials
(3-(difluoromethyl)-1-(4-methoxyphenyl)-5-(4-(methylsulfinyl)phenyl)pyrazole)
Recent Studies (post-2010)
(3-(difluoromethyl)-1-(4-methoxyphenyl)-5-(4-(methylsulfinyl)phenyl)pyrazole)
Studies
(prazosin)
Trials
(prazosin)
Recent Studies (post-2010) (prazosin)
11007,914713682

Protein Interaction Comparison

ProteinTaxonomy3-(difluoromethyl)-1-(4-methoxyphenyl)-5-(4-(methylsulfinyl)phenyl)pyrazole (IC50)prazosin (IC50)
Solute carrier family 22 member 1 Homo sapiens (human)5.87
Interstitial collagenaseHomo sapiens (human)4.036
Alpha-2A adrenergic receptorHomo sapiens (human)2.638
Matrix metalloproteinase-9Homo sapiens (human)6.963
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)0.0008
Ribosyldihydronicotinamide dehydrogenase [quinone]Homo sapiens (human)0.0078
Alpha-2B adrenergic receptorHomo sapiens (human)0.29
Alpha-2C adrenergic receptorHomo sapiens (human)0.647
Alpha-1D adrenergic receptorRattus norvegicus (Norway rat)0.0008
Alpha-1D adrenergic receptorHomo sapiens (human)0.0007
Bromodomain-containing protein 2Homo sapiens (human)0.0009
Alpha-1A adrenergic receptorHomo sapiens (human)0.0006
Alpha-1B adrenergic receptorHomo sapiens (human)0.0006
5-hydroxytryptamine receptor 2BHomo sapiens (human)4.118
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)0.0008
5-hydroxytryptamine receptor 7Cavia porcellus (domestic guinea pig)9.9
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)1.5849
Multidrug and toxin extrusion protein 1Homo sapiens (human)1.6

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Goto, T; Ochi, T1

Other Studies

1 other study(ies) available for 3-(difluoromethyl)-1-(4-methoxyphenyl)-5-(4-(methylsulfinyl)phenyl)pyrazole and prazosin

ArticleYear
The antinociceptive effect of FR140423 in mice: involvement of spinal alpha(2)-adrenoceptors.
    European journal of pharmacology, 2000, Jul-21, Volume: 400, Issue:2-3

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Analgesics; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Drug Interactions; Injections, Intraventricular; Injections, Spinal; Male; Mice; Morphine; Nociceptors; Pain Measurement; Phentolamine; Prazosin; Propranolol; Pyrazoles; Receptors, Adrenergic, alpha-2; Spinal Cord; Sulfoxides; Yohimbine

2000