3-(difluoromethyl)-1-(4-methoxyphenyl)-5-(4-(methylsulfinyl)phenyl)pyrazole and dinoprostone

3-(difluoromethyl)-1-(4-methoxyphenyl)-5-(4-(methylsulfinyl)phenyl)pyrazole has been researched along with dinoprostone in 2 studies

Compound Research Comparison

Studies (3-(difluoromethyl)-1-(4-methoxyphenyl)-5-(4-(methylsulfinyl)phenyl)pyrazole)	Trials (3-(difluoromethyl)-1-(4-methoxyphenyl)-5-(4-(methylsulfinyl)phenyl)pyrazole)	Recent Studies (post-2010) (3-(difluoromethyl)-1-(4-methoxyphenyl)-5-(4-(methylsulfinyl)phenyl)pyrazole)	Studies (dinoprostone)	Trials (dinoprostone)	Recent Studies (post-2010) (dinoprostone)
11	0	0	29,105	1,346	6,357

Protein Interaction Comparison

Protein	Taxonomy	dinoprostone (IC50)
Prostaglandin E2 receptor EP1 subtype	Homo sapiens (human)	0.0155
Prostaglandin E2 receptor EP4 subtype	Homo sapiens (human)	0.0031
Prostaglandin E2 receptor EP4 subtype	Rattus norvegicus (Norway rat)	0.0021
Prostaglandin E2 receptor EP3 subtype	Homo sapiens (human)	0.002
Prostaglandin E2 receptor EP2 subtype	Homo sapiens (human)	0.0087
Prostacyclin receptor	Homo sapiens (human)	0.26
Prostaglandin E2 receptor EP2 subtype	Rattus norvegicus (Norway rat)	0.0052

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (50.00)	18.2507
2000's	1 (50.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Fujii, T; Jobo-Magari, K; Matsumori, K; Ochi, T; Yonezawa, A	1
Goto, T; Ochi, T	1

Other Studies

2 other study(ies) available for 3-(difluoromethyl)-1-(4-methoxyphenyl)-5-(4-(methylsulfinyl)phenyl)pyrazole and dinoprostone

Article	Year
Anti-inflammatory and analgesic effects of a novel pyrazole derivative, FR140423. European journal of pharmacology, 1999, Jan-22, Volume: 365, Issue:2-3 Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Female; Fungi; Indomethacin; Isoenzymes; Male; Membrane Proteins; Molecular Structure; Naloxone; Pain Measurement; Peptic Ulcer; Peroxidases; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Pyrazolones; Rats; Rats, Inbred Lew; Rats, Sprague-Dawley; Recombinant Proteins; Sulfoxides	1999
Anti-inflammatory activity of a novel selective cyclooxygenase-2 inhibitor, FR140423, on type II collagen-induced arthritis in Lewis rats. Prostaglandins & other lipid mediators, 2001, Volume: 66, Issue:4 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Arthritis; Collagen; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Edema; Female; Gastric Mucosa; Indomethacin; Isoenzymes; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Inbred Lew; Sulfoxides; Thromboxane B2	2001

Article

Year

Anti-inflammatory and analgesic effects of a novel pyrazole derivative, FR140423.

European journal of pharmacology, 1999, Jan-22, Volume: 365, Issue:2-3

Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Female; Fungi; Indomethacin; Isoenzymes; Male; Membrane Proteins; Molecular Structure; Naloxone; Pain Measurement; Peptic Ulcer; Peroxidases; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Pyrazolones; Rats; Rats, Inbred Lew; Rats, Sprague-Dawley; Recombinant Proteins; Sulfoxides

1999

Anti-inflammatory activity of a novel selective cyclooxygenase-2 inhibitor, FR140423, on type II collagen-induced arthritis in Lewis rats.

Prostaglandins & other lipid mediators, 2001, Volume: 66, Issue:4

Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Arthritis; Collagen; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Edema; Female; Gastric Mucosa; Indomethacin; Isoenzymes; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Inbred Lew; Sulfoxides; Thromboxane B2

2001