3-(4-(4-phenyl-1,2,3,6-tetrahydropyridyl-1)-butyl)indole has been researched along with apomorphine in 8 studies
| Studies (3-(4-(4-phenyl-1,2,3,6-tetrahydropyridyl-1)-butyl)indole) | Trials (3-(4-(4-phenyl-1,2,3,6-tetrahydropyridyl-1)-butyl)indole) | Recent Studies (post-2010) (3-(4-(4-phenyl-1,2,3,6-tetrahydropyridyl-1)-butyl)indole) | Studies (apomorphine) | Trials (apomorphine) | Recent Studies (post-2010) (apomorphine) |
|---|---|---|---|---|---|
| 18 | 1 | 0 | 9,205 | 287 | 780 |
| Protein | Taxonomy | 3-(4-(4-phenyl-1,2,3,6-tetrahydropyridyl-1)-butyl)indole (IC50) | apomorphine (IC50) |
|---|---|---|---|
| Tryptophan 5-hydroxylase 1 | Rattus norvegicus (Norway rat) | 0.22 | |
| D(2) dopamine receptor | Homo sapiens (human) | 0.0146 | |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | 7.75 | |
| D | Rattus norvegicus (Norway rat) | 0.4744 | |
| D(3) dopamine receptor | Rattus norvegicus (Norway rat) | 0.1432 | |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.063 | |
| D(2) dopamine receptor | Bos taurus (cattle) | 0.3385 | |
| D(1A) dopamine receptor | Homo sapiens (human) | 0.025 | |
| D(4) dopamine receptor | Homo sapiens (human) | 0.025 | |
| D(1B) dopamine receptor | Homo sapiens (human) | 0.025 | |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | 0.063 | |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.063 | |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | 7.75 | |
| D(1B) dopamine receptor | Rattus norvegicus (Norway rat) | 0.1432 | |
| D(4) dopamine receptor | Rattus norvegicus (Norway rat) | 0.1432 | |
| D(3) dopamine receptor | Homo sapiens (human) | 0.025 | |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | 7.75 | |
| D(2) dopamine receptor | Rattus norvegicus (Norway rat) | 0.0813 | |
| E3 ubiquitin-protein ligase Mdm2 | Homo sapiens (human) | 0.205 | |
| 5-hydroxytryptamine receptor 4 | Rattus norvegicus (Norway rat) | 1.35 | |
| D | Bos taurus (cattle) | 0.3385 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (87.50) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bean, AJ; During, MJ; Roth, RH | 1 |
| Nichols, NF; Schreur, PJ | 1 |
| Agnati, L; Fuxe, K; Goldstein, M; Mascagni, FM; Meller, E; Seyfried, CA | 1 |
| Bohmaker, K; Friedhoff, AJ; Goldstein, M; Meller, E; Schweitzer, JW | 1 |
| Adler, CH; Bohmaker, K; Friedhoff, AJ; Goldstein, M; Helmer-Matyjek, E; Meller, E | 1 |
| Roth, RH; Wolf, ME | 1 |
| Bunney, BS; Chiodo, LA | 1 |
| Agnati, LF; Fuxe, K; Seyfried, CA; Wolf, HP | 1 |
8 other study(ies) available for 3-(4-(4-phenyl-1,2,3,6-tetrahydropyridyl-1)-butyl)indole and apomorphine
| Article | Year |
|---|---|
Effects of dopamine autoreceptor stimulation on the release of colocalized transmitters: in vivo release of dopamine and neurotensin from rat prefrontal cortex.
Topics: Animals; Apomorphine; Dopamine; Frontal Lobe; Indoles; Male; Neurotensin; Rats; Rats, Inbred Strains; Receptors, Dopamine | 1990 |
Two automated locomotor activity tests for dopamine autoreceptor agonists.
Topics: Amphetamine; Animals; Antipsychotic Agents; Apomorphine; Drug Evaluation, Preclinical; Exploratory Behavior; Indoles; Male; Motor Activity; Piperidines; Rats; Rats, Inbred Strains; Receptors, Dopamine | 1986 |
The characterization of the dopaminergic profile of EMD 23,448, and indolyl-3-butylamine: selective actions on presynaptic and supersensitive postsynaptic DA receptor populations.
Topics: Acetylcholine; Adrenergic Agonists; Animals; Apomorphine; Behavior, Animal; Brain; Catecholamines; Dihydroxyphenylalanine; Dopamine; Indoles; Male; Rats; Rats, Inbred Strains; Receptors, Dopamine | 1987 |
Chronic haloperidol does not alter agonist affinity for dopamine receptors in vitro.
Topics: Animals; Apomorphine; Binding, Competitive; Corpus Striatum; Haloperidol; Indoles; Male; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Spiperone | 1985 |
Receptor reserve at striatal dopamine autoreceptors: implications for selectivity of dopamine agonists.
Topics: 4-Butyrolactone; Animals; Apomorphine; Corpus Striatum; Indoles; Levodopa; Male; Quinolines; Rats; Rats, Inbred Strains; Receptors, Dopamine | 1986 |
Dopamine autoreceptor stimulation increases protein carboxyl methylation in striatal slices.
Topics: Animals; Apomorphine; Corpus Striatum; Dose-Response Relationship, Drug; Indoles; Male; Methionine; Protein Methyltransferases; Protein O-Methyltransferase; Rats; Rats, Inbred Strains; Receptors, Dopamine; Reserpine; Time Factors | 1985 |
Electrophysiological studies on EMD 23 448, an indolyl-3-butylamine, in the rat: a putative selective dopamine autoreceptor agonist.
Topics: Acetylcholine; Animals; Apomorphine; Blood Pressure; Dopamine; Electrophysiology; Glutamates; Glutamic Acid; Indoles; Male; Neurons; Rats; Rats, Inbred Strains; Receptors, Dopamine | 1983 |
Demonstration of a new type of dopamine receptor agonist: an indolyl-3-butylamine. Actions at intact versus supersensitive dopamine receptors in the rat forebrain.
Topics: Animals; Apomorphine; Behavior, Animal; Brain; Dopamine; Dose-Response Relationship, Drug; Indoles; Rats; Receptors, Dopamine; Rotation | 1982 |