3-(3-amino-1,2,4-oxadiazol-5-yl)-5-chloro-2,6-pyrazinediamine has been researched along with amiloride in 3 studies
| Studies (3-(3-amino-1,2,4-oxadiazol-5-yl)-5-chloro-2,6-pyrazinediamine) | Trials (3-(3-amino-1,2,4-oxadiazol-5-yl)-5-chloro-2,6-pyrazinediamine) | Recent Studies (post-2010) (3-(3-amino-1,2,4-oxadiazol-5-yl)-5-chloro-2,6-pyrazinediamine) | Studies (amiloride) | Trials (amiloride) | Recent Studies (post-2010) (amiloride) |
|---|---|---|---|---|---|
| 5 | 0 | 1 | 7,584 | 339 | 788 |
| Protein | Taxonomy | 3-(3-amino-1,2,4-oxadiazol-5-yl)-5-chloro-2,6-pyrazinediamine (IC50) | amiloride (IC50) |
|---|---|---|---|
| Urokinase-type plasminogen activator | Homo sapiens (human) | 4.7 | |
| Urokinase-type plasminogen activator | Mus musculus (house mouse) | 2.3 | |
| Amine oxidase [flavin-containing] A | Homo sapiens (human) | 3.909 | |
| Sodium/hydrogen exchanger 1 | Rattus norvegicus (Norway rat) | 1 | |
| Amiloride-sensitive sodium channel subunit alpha | Homo sapiens (human) | 0.776 | |
| Sodium/hydrogen exchanger 2 | Oryctolagus cuniculus (rabbit) | 1 | |
| Acid-sensing ion channel 3 | Homo sapiens (human) | 4.4 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Blaine, EH; Bock, MG; Cragoe, EJ; Smith, RL | 1 |
| Abramcheck, FJ; Helman, SI; Van Driessche, W | 1 |
| Benos, DJ; Watthey, JW | 1 |
3 other study(ies) available for 3-(3-amino-1,2,4-oxadiazol-5-yl)-5-chloro-2,6-pyrazinediamine and amiloride
| Article | Year |
|---|---|
Synthesis and biological activity of 3-amino-5-(3,5-diamino-6-chloropyrazin-2-yl)-1,2,4-oxadiazole: an amiloride prodrug.
Topics: Amiloride; Animals; Chlorides; Diuresis; Dogs; Dosage Forms; Magnetic Resonance Spectroscopy; Natriuresis; Potassium; Pyrazines; Rats; Structure-Activity Relationship | 1986 |
Autoregulation of apical membrane Na+ permeability of tight epithelia. Noise analysis with amiloride and CGS 4270.
Topics: Amiloride; Animals; Cell Membrane Permeability; Electricity; Epithelium; Homeostasis; Ion Channels; Physiology; Pyrazines; Quinidine; Quinine; Rana pipiens; Skin; Sodium | 1985 |
Inferences on the nature of the apical sodium entry site in frog skin epithelium.
Topics: Amiloride; Animals; Benzimidazoles; Biological Transport; Epithelium; In Vitro Techniques; Oxadiazoles; Pyrazines; Rana catesbeiana; Skin; Sodium; Structure-Activity Relationship | 1981 |