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3-(3,4-difluorophenyl)-4-(4-(methylsulfonyl)phenyl)-2(5h)-furanone and naproxen

3-(3,4-difluorophenyl)-4-(4-(methylsulfonyl)phenyl)-2(5h)-furanone has been researched along with naproxen in 1 studies

Compound Research Comparison

Studies
(3-(3,4-difluorophenyl)-4-(4-(methylsulfonyl)phenyl)-2(5h)-furanone)
Trials
(3-(3,4-difluorophenyl)-4-(4-(methylsulfonyl)phenyl)-2(5h)-furanone)
Recent Studies (post-2010)
(3-(3,4-difluorophenyl)-4-(4-(methylsulfonyl)phenyl)-2(5h)-furanone)
Studies
(naproxen)
Trials
(naproxen)
Recent Studies (post-2010) (naproxen)
25024,5511,0571,429

Protein Interaction Comparison

ProteinTaxonomy3-(3,4-difluorophenyl)-4-(4-(methylsulfonyl)phenyl)-2(5h)-furanone (IC50)naproxen (IC50)
Prostaglandin G/H synthase 1Ovis aries (sheep)1.1642
Hormone-sensitive lipaseRattus norvegicus (Norway rat)1.2
Prostaglandin G/H synthase 1Homo sapiens (human)4.0203
Prostaglandin G/H synthase 2Homo sapiens (human)3.8725
Prostaglandin G/H synthase 2 Rattus norvegicus (Norway rat)0.06
Aldo-keto reductase family 1 member C3Homo sapiens (human)0.5867
Aldo-keto reductase family 1 member C2 Homo sapiens (human)1.26
Prostaglandin G/H synthase 2Ovis aries (sheep)3.36
Solute carrier family 22 member 6Homo sapiens (human)5.8
Prostaglandin G/H synthase 1 Rattus norvegicus (Norway rat)0.06

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Anwyl, R; Ashe, KH; Cleary, J; Cole, G; Falinska, A; Frautschy, S; Kotilinek, LA; Lesne, S; Lim, GP; Panizzon, K; Rowan, M; Simonyi, A; Sun, GY; Wallis, RA; Wang, Q; Westerman, MA; Younkin, LH; Younkin, SG1

Other Studies

1 other study(ies) available for 3-(3,4-difluorophenyl)-4-(4-(methylsulfonyl)phenyl)-2(5h)-furanone and naproxen

ArticleYear
Cyclooxygenase-2 inhibition improves amyloid-beta-mediated suppression of memory and synaptic plasticity.
    Brain : a journal of neurology, 2008, Volume: 131, Issue:Pt 3

    Topics: Amyloid beta-Peptides; Animals; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Furans; Hippocampus; Ibuprofen; Inflammation Mediators; Interleukin-1beta; Male; Memory; Memory Disorders; Mice; Mice, Inbred C57BL; Naproxen; Neuronal Plasticity; Peptide Fragments; Rats; Synapses; Tumor Necrosis Factor-alpha

2008