3-(3,4-difluorophenyl)-4-(4-(methylsulfonyl)phenyl)-2(5h)-furanone has been researched along with ibuprofen in 2 studies
| Studies (3-(3,4-difluorophenyl)-4-(4-(methylsulfonyl)phenyl)-2(5h)-furanone) | Trials (3-(3,4-difluorophenyl)-4-(4-(methylsulfonyl)phenyl)-2(5h)-furanone) | Recent Studies (post-2010) (3-(3,4-difluorophenyl)-4-(4-(methylsulfonyl)phenyl)-2(5h)-furanone) | Studies (ibuprofen) | Trials (ibuprofen) | Recent Studies (post-2010) (ibuprofen) |
|---|---|---|---|---|---|
| 25 | 0 | 2 | 10,245 | 1,781 | 4,267 |
| Protein | Taxonomy | 3-(3,4-difluorophenyl)-4-(4-(methylsulfonyl)phenyl)-2(5h)-furanone (IC50) | ibuprofen (IC50) |
|---|---|---|---|
| Prostaglandin G/H synthase 1 | Bos taurus (cattle) | 2.9 | |
| Prostaglandin G/H synthase 2 | Bos taurus (cattle) | 1.1 | |
| Albumin | Bos taurus (cattle) | 3 | |
| Prostaglandin G/H synthase 1 | Ovis aries (sheep) | 4.0919 | |
| Prostaglandin G/H synthase 1 | Mus musculus (house mouse) | 0.22 | |
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | 1.6273 | |
| Caspase-1 | Homo sapiens (human) | 7.2667 | |
| Substance-P receptor | Cavia porcellus (domestic guinea pig) | 1.1 | |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | 3.0687 | |
| Prostaglandin G/H synthase 2 | Rattus norvegicus (Norway rat) | 1.3 | |
| Aldo-keto reductase family 1 member C3 | Homo sapiens (human) | 10 | |
| Caspase-3 | Homo sapiens (human) | 7.2667 | |
| Caspase-4 | Homo sapiens (human) | 7.2667 | |
| 4-aminobutyrate aminotransferase, mitochondrial | Rattus norvegicus (Norway rat) | 1.1 | |
| Caspase-5 | Homo sapiens (human) | 7.2667 | |
| Caspase-9 | Homo sapiens (human) | 7.2667 | |
| Prostaglandin G/H synthase 2 | Ovis aries (sheep) | 1.1375 | |
| Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | 2.9 | |
| Fatty-acid amide hydrolase 1 | Rattus norvegicus (Norway rat) | 5 | |
| Prostaglandin G/H synthase 2 | Mus musculus (house mouse) | 0.54 | |
| Solute carrier family 22 member 6 | Homo sapiens (human) | 8 | |
| Prostaglandin G/H synthase 1 | Rattus norvegicus (Norway rat) | 1.3 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Asif, M; Husain, A; Iqbal, MA; Iram, F; Khan, SA | 1 |
| Anwyl, R; Ashe, KH; Cleary, J; Cole, G; Falinska, A; Frautschy, S; Kotilinek, LA; Lesne, S; Lim, GP; Panizzon, K; Rowan, M; Simonyi, A; Sun, GY; Wallis, RA; Wang, Q; Westerman, MA; Younkin, LH; Younkin, SG | 1 |
1 review(s) available for 3-(3,4-difluorophenyl)-4-(4-(methylsulfonyl)phenyl)-2(5h)-furanone and ibuprofen
| Article | Year |
|---|---|
Insights into the chemistry and therapeutic potential of furanones: A versatile pharmacophore.
Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antifungal Agents; Antineoplastic Agents; Antiviral Agents; Humans; Molecular Structure | 2019 |
1 other study(ies) available for 3-(3,4-difluorophenyl)-4-(4-(methylsulfonyl)phenyl)-2(5h)-furanone and ibuprofen
| Article | Year |
|---|---|
Cyclooxygenase-2 inhibition improves amyloid-beta-mediated suppression of memory and synaptic plasticity.
Topics: Amyloid beta-Peptides; Animals; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Furans; Hippocampus; Ibuprofen; Inflammation Mediators; Interleukin-1beta; Male; Memory; Memory Disorders; Mice; Mice, Inbred C57BL; Naproxen; Neuronal Plasticity; Peptide Fragments; Rats; Synapses; Tumor Necrosis Factor-alpha | 2008 |