3-(3,4-difluorophenyl)-4-(4-(methylsulfonyl)phenyl)-2(5h)-furanone has been researched along with cj-042794 in 1 studies
| Studies (3-(3,4-difluorophenyl)-4-(4-(methylsulfonyl)phenyl)-2(5h)-furanone) | Trials (3-(3,4-difluorophenyl)-4-(4-(methylsulfonyl)phenyl)-2(5h)-furanone) | Recent Studies (post-2010) (3-(3,4-difluorophenyl)-4-(4-(methylsulfonyl)phenyl)-2(5h)-furanone) | Studies (cj-042794) | Trials (cj-042794) | Recent Studies (post-2010) (cj-042794) |
|---|---|---|---|---|---|
| 25 | 0 | 2 | 5 | 0 | 2 |
| Protein | Taxonomy | 3-(3,4-difluorophenyl)-4-(4-(methylsulfonyl)phenyl)-2(5h)-furanone (IC50) | cj-042794 (IC50) |
|---|---|---|---|
| Prostaglandin E2 receptor EP4 subtype | Homo sapiens (human) | 0.0169 | |
| Prostaglandin E2 receptor EP2 subtype | Homo sapiens (human) | 0.709 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Blouin, M; Burch, J; Clark, P; Denis, D; Ducharme, Y; Farand, J; Friesen, R; Gaudreault, M; Han, Y; Lévesque, JF; Mathieu, MC; Mellon, C; O'Neill, G; Rowland, S; Stocco, R; Therien, A; Vigneault, E; Wrona, M; Xu, D | 1 |
1 other study(ies) available for 3-(3,4-difluorophenyl)-4-(4-(methylsulfonyl)phenyl)-2(5h)-furanone and cj-042794
| Article | Year |
|---|---|
The discovery of 4-{1-[({2,5-dimethyl-4-[4-(trifluoromethyl)benzyl]-3-thienyl}carbonyl)amino]cyclopropyl}benzoic acid (MK-2894), a potent and selective prostaglandin E2 subtype 4 receptor antagonist.
Topics: Analgesics; Animals; Benzoates; Cyclopropanes; Half-Life; Humans; Magnetic Resonance Spectroscopy; Male; Pain; Prostaglandin Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Prostaglandin E; Structure-Activity Relationship; Thiophenes | 2010 |