3-(3-(dimethylamino)propyl)-4-hydroxy-n-(4-(4-pyridinyl)phenyl)benzamide has been researched along with sumatriptan in 4 studies
| Studies (3-(3-(dimethylamino)propyl)-4-hydroxy-n-(4-(4-pyridinyl)phenyl)benzamide) | Trials (3-(3-(dimethylamino)propyl)-4-hydroxy-n-(4-(4-pyridinyl)phenyl)benzamide) | Recent Studies (post-2010) (3-(3-(dimethylamino)propyl)-4-hydroxy-n-(4-(4-pyridinyl)phenyl)benzamide) | Studies (sumatriptan) | Trials (sumatriptan) | Recent Studies (post-2010) (sumatriptan) |
|---|---|---|---|---|---|
| 27 | 0 | 4 | 2,405 | 461 | 480 |
| Protein | Taxonomy | 3-(3-(dimethylamino)propyl)-4-hydroxy-n-(4-(4-pyridinyl)phenyl)benzamide (IC50) | sumatriptan (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 3E | Homo sapiens (human) | 0.0073 | |
| 5-hydroxytryptamine receptor 3B | Homo sapiens (human) | 0.0073 | |
| 5-hydroxytryptamine receptor 1A | Homo sapiens (human) | 0.4497 | |
| Carboxypeptidase M | Homo sapiens (human) | 0.02 | |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.64 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 0.722 | |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | 0.64 | |
| 5-hydroxytryptamine receptor 1D | Homo sapiens (human) | 0.3091 | |
| 5-hydroxytryptamine receptor 1B | Homo sapiens (human) | 0.0131 | |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 7.9433 | |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | 3.9753 | |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | 0.804 | |
| 5-hydroxytryptamine receptor 1D | Rattus norvegicus (Norway rat) | 0.061 | |
| 5-hydroxytryptamine receptor 1E | Homo sapiens (human) | 5.5 | |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.64 | |
| 5-hydroxytryptamine receptor 3A | Homo sapiens (human) | 0.0078 | |
| 5-hydroxytryptamine receptor 5A | Homo sapiens (human) | 0.5012 | |
| 5-hydroxytryptamine receptor 1D | Sus scrofa (pig) | 0.02 | |
| 5-hydroxytryptamine receptor 1A | Mus musculus (house mouse) | 0.45 | |
| 5-hydroxytryptamine receptor 3D | Homo sapiens (human) | 0.0073 | |
| 5-hydroxytryptamine receptor 3C | Homo sapiens (human) | 0.0073 | |
| Multidrug and toxin extrusion protein 1 | Homo sapiens (human) | 6.7 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bax, WA; Maassen VanDenBrink, A; Reekers, M; Saxena, PR | 1 |
| Emre-Aydíngöz, S; Erdem, SR; Tuncer, M | 1 |
| Jeggo, RD; Jordan, D; Ramage, AG; Wang, Y | 1 |
| Chan, KY; Danser, AH; de Vries, R; Leijten, FP; MaassenVanDenBrink, A; Pfannkuche, HJ; van den Bogaerdt, AJ | 1 |
4 other study(ies) available for 3-(3-(dimethylamino)propyl)-4-hydroxy-n-(4-(4-pyridinyl)phenyl)benzamide and sumatriptan
| Article | Year |
|---|---|
Human isolated coronary artery contraction to sumatriptan characterised by the selective 5-HT1B/1D receptor antagonist GR55562.
Topics: Benzamides; Coronary Vessels; Dinoprost; Dose-Response Relationship, Drug; Drug Interactions; Humans; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Potassium; Pyridines; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Substance P; Sumatriptan; Vasoconstrictor Agents | 2000 |
Relaxation induced by serotonin and sumatriptan in isolated guinea pig gallbladder strips.
Topics: Adrenergic beta-Antagonists; Animals; Benzamides; Dose-Response Relationship, Drug; Female; Free Radical Scavengers; Gallbladder; Guinea Pigs; In Vitro Techniques; Male; Muscle Relaxation; Propranolol; Pyridines; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sumatriptan | 2001 |
Activation of 5-HT1B and 5-HT1D receptors in the rat nucleus tractus solitarius: opposing action on neurones that receive an excitatory vagal C-fibre afferent input.
Topics: Action Potentials; Animals; Benzamides; Drug Synergism; Electric Stimulation; Iontophoresis; Ketanserin; Male; Neural Inhibition; Neurons; Neurons, Afferent; Patch-Clamp Techniques; Pyridines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Serotonin 5-HT1 Receptor Agonists; Serotonin Antagonists; Serotonin Receptor Agonists; Solitary Nucleus; Sumatriptan; Time Factors; Vagus Nerve | 2007 |
Functional characterization of contractions to tegaserod in human isolated proximal and distal coronary arteries.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adolescent; Adult; Benzamides; Coronary Vessels; Female; Humans; In Vitro Techniques; Indoles; Male; Middle Aged; Muscle Contraction; Pyridines; Receptors, Serotonin, 5-HT4; RNA, Messenger; Serotonin 5-HT4 Receptor Agonists; Serotonin Receptor Agonists; Sumatriptan; Vasoconstrictor Agents; Young Adult | 2009 |