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3-(2-carboxypiperazine-4-yl)propyl-1-phosphate and 2-amino-5-phosphonovalerate

3-(2-carboxypiperazine-4-yl)propyl-1-phosphate has been researched along with 2-amino-5-phosphonovalerate in 4 studies

*2-Amino-5-phosphonovalerate: The D-enantiomer is a potent and specific antagonist of NMDA glutamate receptors (RECEPTORS, N-METHYL-D-ASPARTATE). The L form is inactive at NMDA receptors but may affect the AP4 (2-amino-4-phosphonobutyrate; APB) excitatory amino acid receptors. [MeSH]

*2-Amino-5-phosphonovalerate: The D-enantiomer is a potent and specific antagonist of NMDA glutamate receptors (RECEPTORS, N-METHYL-D-ASPARTATE). The L form is inactive at NMDA receptors but may affect the AP4 (2-amino-4-phosphonobutyrate; APB) excitatory amino acid receptors. [MeSH]

Compound Research Comparison

Studies
(3-(2-carboxypiperazine-4-yl)propyl-1-phosphate)
Trials
(3-(2-carboxypiperazine-4-yl)propyl-1-phosphate)
Recent Studies (post-2010)
(3-(2-carboxypiperazine-4-yl)propyl-1-phosphate)
Studies
(2-amino-5-phosphonovalerate)
Trials
(2-amino-5-phosphonovalerate)
Recent Studies (post-2010) (2-amino-5-phosphonovalerate)
15004,3931539

Protein Interaction Comparison

ProteinTaxonomy3-(2-carboxypiperazine-4-yl)propyl-1-phosphate (IC50)2-amino-5-phosphonovalerate (IC50)
Glutamate receptor ionotropic, NMDA 1 Rattus norvegicus (Norway rat)0.29
Glutamate receptor ionotropic, NMDA 2A Rattus norvegicus (Norway rat)0.29
Glutamate receptor ionotropic, NMDA 2BRattus norvegicus (Norway rat)0.29
Glutamate receptor ionotropic, NMDA 2CRattus norvegicus (Norway rat)0.29
Glutamate receptor ionotropic, NMDA 2DRattus norvegicus (Norway rat)0.29
Glutamate receptor ionotropic, NMDA 3BRattus norvegicus (Norway rat)0.29
Glutamate receptor ionotropic, NMDA 3ARattus norvegicus (Norway rat)0.29

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Baranauskas, G; Nistri, A1
Nishikawa, T; Takahashi, K; Umino, A; Yoshida, Y1
Ahmad, M; Bigge, C; Chen, X; Johnson, PS; Kumar, KN; Michaelis, EK; Pal, R; Ragland, T1
Mienville, JM; Pesold, C1

Other Studies

4 other study(ies) available for 3-(2-carboxypiperazine-4-yl)propyl-1-phosphate and 2-amino-5-phosphonovalerate

ArticleYear
NMDA receptor-independent mechanisms responsible for the rate of rise of cumulative depolarization evoked by trains of dorsal root stimuli on rat spinal motoneurones.
    Brain research, 1996, Nov-04, Volume: 738, Issue:2

    Topics: 2-Amino-5-phosphonovalerate; Animals; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; Membrane Potentials; Motor Neurons; Neurokinin-1 Receptor Antagonists; Piperazines; Piperidines; Quinuclidines; Rats; Receptors, N-Methyl-D-Aspartate; Spinal Nerve Roots

1996
Evidence for N-methyl-D-aspartate receptor-mediated increase in norepinephrine utilization in the prefrontal cortex of unanesthetized rats.
    Brain research, 1997, Jan-02, Volume: 744, Issue:1

    Topics: 2-Amino-5-phosphonovalerate; Adrenergic Agents; Animals; Binding, Competitive; Consciousness; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Male; Microinjections; N-Methylaspartate; Norepinephrine; Oxidopamine; Phencyclidine; Piperazines; Prefrontal Cortex; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Sympathomimetics; Tritium

1997
Cloning of a brain N-methyl-D-aspartate- and D, L-epsilon-2-amino-4-propyl-5-phosphono-3-pentanoic acid (CGP 39653)-binding protein.
    Biochemical and biophysical research communications, 1998, Dec-18, Volume: 253, Issue:2

    Topics: 2-Amino-5-phosphonovalerate; Amino Acid Sequence; Animals; Base Sequence; Carrier Proteins; Cloning, Molecular; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; Male; Molecular Sequence Data; N-Methylaspartate; Nerve Tissue Proteins; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate

1998
Low resting potential and postnatal upregulation of NMDA receptors may cause Cajal-Retzius cell death.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1999, Mar-01, Volume: 19, Issue:5

    Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Adenosine Triphosphate; Aging; Animals; Cell Death; Cerebral Cortex; Dizocilpine Maleate; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Immunohistochemistry; In Vitro Techniques; Meglumine; Membrane Potentials; N-Methylaspartate; Neurons; Neuroprotective Agents; Patch-Clamp Techniques; Piperazines; Rats; Rats, Inbred F344; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin; Up-Regulation

1999