3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid has been researched along with piperidines in 36 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (19.44) | 18.7374 |
| 1990's | 14 (38.89) | 18.2507 |
| 2000's | 9 (25.00) | 29.6817 |
| 2010's | 6 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Britt, M; Paschetto, KA; Powel, RJ; Pullan, LM; Stumpo, RJ | 1 |
| Bakker, MH; Foster, AC | 1 |
| Chaki, S; Muramatsu, M; Otomo, S; Usuki-Ito, C | 1 |
| Baudrie, V; Chaouloff, F; Laude, D | 1 |
| Bigge, CF; Bobovski, TP; Brahce, LJ; Coughenour, LL; Drummond, JT; Hays, SJ; Johnson, G; Novak, PM; Rice, MJ | 1 |
| Ferkany, JW; Kaplita, PV | 1 |
| Kim, HS; Lehmann, J; Martin, LL; Rao, TS; Wood, PL | 1 |
| Meldrum, BS; Swan, JH | 1 |
| Dziki, M; Ikonomidou, C; Parada-Turska, J; Turski, WA; Urbanska, E | 1 |
| Cler, JA; Iyengar, S; Mick, SJ; Rao, TS; Wood, PL | 1 |
| D'Angio, M; Scatton, B; Serrano, A | 1 |
| Jackson, A; Sanger, DJ | 1 |
| Arbilla, S; Benavides, J; Carter, C; Legendre, P; Lloyd, KG; MacKenzie, ET; Noel, F; Thuret, F; Vincent, JD; Zivkovic, B | 1 |
| Boast, CA; Gerhardt, SC; Jarvis, MF; Murphy, DE; Williams, M | 1 |
| Loo, PS; Sills, MA; Williams, M | 1 |
| Boast, CA; Etienne, PE; Gerhardt, SC; Lehmann, J; Liebman, JM; Pastor, G | 1 |
| Boast, CA; Pastor, G | 1 |
| Ammendola, D; De Sarro, A; De Sarro, G; Nava, F | 1 |
| Doyle, KM; Shaw, GG | 1 |
| Klockgether, T; Löschmann, PA; Petersen, V; Steinbach, JP; Turski, L; Wüllner, U | 1 |
| Doyle, KM; Eddleston, A; Feerick, S; Higgins, GA; Kirkby, DL | 1 |
| Elliot, J; Grimwood, S; Huscroft, I; Hutson, PH; Kennedy, J; Mohnen, K; Murray, F; Russell, MG | 1 |
| Gemignani, A; Paudice, P; Pittaluga, A; Raiteri, M | 1 |
| Aoki, K; Narita, M; Nomura, M; Suzuki, T; Yoshizawa, K | 1 |
| Moriyama, T; Okuda, K; Sakurada, C; Sakurada, S; Sakurada, T; Sugiyama, A; Tan-No, K; Watanabe, C | 1 |
| Balducci, C; Baviera, M; Invernizzi, RW; Mirjana, C | 1 |
| Bertram, EH; Kapur, J; Williamson, J; Yen, W | 1 |
| Baviera, M; Calcagno, E; Carli, M; Ceglia, I; Invernizzi, RW; Renoldi, G | 1 |
| Balducci, C; Baviera, M; Carli, M; Invernizzi, RW | 1 |
| Baviera, M; Calcagno, E; Carli, M; Invernizzi, RW | 1 |
| Ahn, DK; Bae, YC; Bonfa, E; Park, MK; Woo, YW; Yang, GY | 1 |
| Bagot, RC; Dong, Z; Ge, Y; Howland, JG; Phillips, AG; Wang, YT; Wong, TP | 1 |
| Cirrito, JR; Goebel, WD; Holtzman, DM; Restivo, JL; Verges, DK | 1 |
| Agnoli, L; Carli, M | 1 |
| Sokabe, M; Tanaka, M | 1 |
| Kouvaros, S; Papatheodoropoulos, C | 1 |
36 other study(ies) available for 3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid and piperidines
| Article | Year |
|---|---|
Neomycin is an agonist at a polyamine site on the N-methyl-D-aspartate receptor.
Topics: Adrenergic alpha-Antagonists; Animals; Biguanides; Magnesium; Male; Neomycin; Phencyclidine; Piperazines; Piperidines; Polyamines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spermidine; Synaptic Membranes; Tritium | 1992 |
An investigation of the mechanisms of delayed neurodegeneration caused by direct injection of quinolinate into the rat striatum in vivo.
Topics: Adrenergic alpha-Antagonists; Animals; Anticonvulsants; Convulsants; Corpus Striatum; Dialysis; Diazepam; Dizocilpine Maleate; Glutamate Decarboxylase; Haloperidol; Ibotenic Acid; Injections; Male; Nerve Degeneration; Pipecolic Acids; Piperazines; Piperidines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Stereotaxic Techniques | 1991 |
Differentiation of the active site of minaprine from that of phencyclidine in rat hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Animals; Binding Sites; Hippocampus; Ketamine; Male; Membranes; N-Methylaspartate; Phencyclidine; Piperazines; Piperidines; Potassium Channels; Pyridazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate | 1990 |
Effects of the 5-HT1C/5-5-HT2 receptor agonists DOI and alpha-methyl-5-HT on plasma glucose and insulin levels in the rat.
Topics: Amphetamines; Animals; Blood Glucose; Catecholamines; Ergolines; Hyperglycemia; Insulin; Male; Piperazines; Piperidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Ritanserin; Serotonin | 1990 |
New and versatile approaches to the synthesis of CPP-related competitive NMDA antagonists. Preliminary structure-activity relationships and pharmacological evaluation.
Topics: Animals; Binding, Competitive; Cerebral Cortex; Chemical Phenomena; Chemistry, Physical; In Vitro Techniques; N-Methylaspartate; Piperazines; Piperidines; Rats; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship; Synaptic Membranes | 1990 |
Evidence for direct interactions between the NMDA and glycine recognition sites in brain.
Topics: Amino Acids; Animals; Brain Chemistry; In Vitro Techniques; Kynurenic Acid; Male; Pipecolic Acids; Piperazines; Piperidines; Rats; Rats, Inbred Strains; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Serine | 1990 |
Selective activation of dopaminergic pathways in the mesocortex by compounds that act at the phencyclidine (PCP) binding site: tentative evidence for PCP recognition sites not coupled to N-methyl-D-aspartate (NMDA) receptors.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Carbazoles; Cerebral Cortex; Dibenzocycloheptenes; Dizocilpine Maleate; Dopamine; Dose-Response Relationship, Drug; Guanidines; Ligands; Male; Neural Pathways; Pipecolic Acids; Piperazines; Piperidines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Receptors, Phencyclidine; Stereoisomerism | 1990 |
Protection by NMDA antagonists against selective cell loss following transient ischaemia.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Brain; Brain Ischemia; Dibenzocycloheptenes; Dizocilpine Maleate; Male; N-Methylaspartate; Neurons; Pipecolic Acids; Piperazines; Piperidines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1990 |
Excitatory amino acid antagonists protect mice against seizures induced by bicuculline.
Topics: Animals; Bicuculline; Dibenzocycloheptenes; Dizocilpine Maleate; Dose-Response Relationship, Drug; Male; Mice; Muscimol; Pipecolic Acids; Piperazines; Piperidines; Receptors, Amino Acid; Receptors, Cell Surface; Seizures | 1990 |
Inhibition of climbing and mossy fiber, and basket and stellate cell inputs to mouse cerebellar Purkinje cells by novel anti-ischemic agents, ifenprodil and BMY-14802.
Topics: Analysis of Variance; Animals; Cyclic GMP; Harmaline; Male; Methamphetamine; Mice; Mice, Inbred Strains; Neurons; Pentylenetetrazole; Piperazines; Piperidines; Purkinje Cells; Pyrimidines; Radioimmunoassay; Receptors, Amino Acid; Receptors, Cell Surface | 1990 |
NMDA antagonists block restraint-induced increase in extracellular DOPAC in rat nucleus accumbens.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic alpha-Antagonists; Animals; Aspartic Acid; Carbolines; Convulsants; Diazepam; Male; N-Methylaspartate; Nucleus Accumbens; Phenylacetates; Piperazines; Piperidines; Rats; Rats, Inbred Strains; Restraint, Physical; Riluzole; Septal Nuclei; Thiazoles | 1989 |
Effects of phencyclidine and other N-methyl-D-aspartate antagonists on the schedule-controlled behavior of rats.
Topics: Animals; Aspartic Acid; Conditioning, Psychological; Dibenzocycloheptenes; Dizocilpine Maleate; Male; N-Methylaspartate; Phenazocine; Phencyclidine; Piperazines; Piperidines; Punishment; Rats; Rats, Inbred Strains; Reinforcement Schedule; Stereoisomerism | 1989 |
Ifenprodil and SL 82.0715 as cerebral anti-ischemic agents. II. Evidence for N-methyl-D-aspartate receptor antagonist properties.
Topics: Animals; Aspartic Acid; Brain Ischemia; Cells, Cultured; Cerebellum; Corpus Striatum; Cyclic GMP; Dopamine; Harmaline; In Vitro Techniques; Mice; N-Methylaspartate; Phencyclidine; Piperazines; Piperidines; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spinal Cord | 1988 |
The novel N-methyl-D-aspartate (NMDA) antagonist CGS 19755 prevents ischemia-induced reductions of adenosine A1, NMDA, and PCP receptors in gerbil brain.
Topics: Adenosine; Animals; Autoradiography; Female; Flunitrazepam; Gerbillinae; Image Processing, Computer-Assisted; Ischemic Attack, Transient; Pipecolic Acids; Piperazines; Piperidines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Receptors, Phencyclidine | 1988 |
The NMDA antagonists, CPP and CGS 19755, lack affinity for central benzodiazepine receptors.
Topics: Animals; Anticonvulsants; Aspartic Acid; Binding, Competitive; Brain; Flunitrazepam; In Vitro Techniques; N-Methylaspartate; Pipecolic Acids; Piperazines; Piperidines; Rats; Receptors, GABA-A | 1988 |
The N-methyl-D-aspartate antagonists CGS 19755 and CPP reduce ischemic brain damage in gerbils.
Topics: Animals; Aspartic Acid; Brain; Female; Gerbillinae; Hippocampus; Ischemic Attack, Transient; Motor Activity; N-Methylaspartate; Neurons; Pipecolic Acids; Piperazines; Piperidines | 1988 |
Characterization of motor activity patterns induced by N-methyl-D-aspartate antagonists in gerbils.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Dose-Response Relationship, Drug; Electronic Data Processing; Female; Gerbillinae; Ketamine; Motor Activity; N-Methylaspartate; Pipecolic Acids; Piperazines; Piperidines; Time Factors | 1987 |
Effects of some excitatory amino acid antagonists on imipenem-induced seizures in DBA/2 mice.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Anticonvulsants; Dizocilpine Maleate; Excitatory Amino Acids; Glutamine; Imipenem; Kynurenic Acid; Mice; Mice, Inbred DBA; Muscimol; Piperazines; Piperidines; Quinoxalines; Seizures | 1995 |
Investigation of the involvement of the N-methyl-D-aspartate receptor macrocomplex in the development of spermine-induced CNS excitation in vivo.
Topics: Animals; Brain; Cerebral Ventricles; Dizocilpine Maleate; Female; Kynurenic Acid; Mice; Neuroprotective Agents; Piperazines; Piperidines; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Seizures; Spermine; Tremor | 1996 |
Effects of the antiparkinsonian drug budipine on central neurotransmitter systems.
Topics: Animals; Antiparkinson Agents; Biperiden; Central Nervous System; Dopamine; Excitatory Amino Acid Antagonists; Male; Mice; Microdialysis; Muscarinic Antagonists; N-Methylaspartate; Neostriatum; Neurotransmitter Agents; Oxidopamine; Piperazines; Piperidines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Rotation; Seizures; Stereotyped Behavior; Sympatholytics | 1996 |
Comparison of various N-methyl-D-aspartate receptor antagonists in a model of short-term memory and on overt behaviour.
Topics: Animals; Behavior, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Male; Memory, Short-Term; Motor Activity; Piperazines; Piperidines; Pyrrolidinones; Rats; Receptors, N-Methyl-D-Aspartate; Reinforcement Schedule | 1998 |
Modulation of [3H]MK-801 binding to NMDA receptors in vivo and in vitro.
Topics: Animals; Binding Sites; Binding, Competitive; Brain; Chromans; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Ketamine; Kinetics; Male; Membranes; Mice; Phencyclidine; Phenols; Piperazines; Piperidines; Pyrrolidinones; Quinolones; Radioligand Assay; Rats; Receptors, N-Methyl-D-Aspartate; Tritium | 2000 |
The HIV-1 coat protein gp120 and some of its fragments potently activate native cerebral NMDA receptors mediating neuropeptide release.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cerebral Cortex; Cholecystokinin; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; HIV Envelope Protein gp120; HIV-1; Indoles; Kynurenic Acid; Male; Maleimides; Neurons; Nitroarginine; Peptide Fragments; Pipecolic Acids; Piperazines; Piperidines; Potassium; Protein Structure, Tertiary; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Somatostatin; Synaptic Transmission; Synaptosomes; Zinc | 2000 |
Role of the NMDA receptor subunit in the expression of the discriminative stimulus effect induced by ketamine.
Topics: Animals; Dextromethorphan; Discrimination Learning; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Guanidines; Ketamine; Ligands; Male; Phencyclidine; Piperazines; Piperidines; Protein Subunits; Rats; Rats, Inbred F344; Receptors, N-Methyl-D-Aspartate; Receptors, sigma | 2001 |
Intrathecal high-dose morphine induces spinally-mediated behavioral responses through NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Binding, Competitive; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Hindlimb; Hyperalgesia; Injections, Spinal; Male; Mice; Mice, Mutant Strains; Morphine; Naloxone; Narcotic Antagonists; Nerve Tissue Proteins; Pain Measurement; Piperazines; Piperidines; Pyrrolidinones; Reaction Time; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid; Spinal Cord; Subarachnoid Space | 2002 |
The serotonin 5-HT2A receptors antagonist M100907 prevents impairment in attentional performance by NMDA receptor blockade in the rat prefrontal cortex.
Topics: Animals; Attention; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Fluorobenzenes; Injections, Subcutaneous; Male; Microinjections; Motor Activity; Piperazines; Piperidines; Prefrontal Cortex; Psychomotor Performance; Rats; Reaction Time; Receptor, Serotonin, 5-HT2A; Receptors, N-Methyl-D-Aspartate; Serial Learning; Serotonin Antagonists | 2004 |
A comparison of three NMDA receptor antagonists in the treatment of prolonged status epilepticus.
Topics: Animals; Dizocilpine Maleate; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Antagonists; Hippocampus; Male; Piperazines; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Status Epilepticus | 2004 |
The 5-HT receptor antagonist M100,907 prevents extracellular glutamate rising in response to NMDA receptor blockade in the mPFC.
Topics: 2-Amino-5-phosphonovalerate; Analysis of Variance; Animals; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Extracellular Space; Fluorobenzenes; Glutamic Acid; Male; Microdialysis; Nicotine; Piperazines; Piperidines; Potassium Chloride; Prefrontal Cortex; Rats; Receptor, Serotonin, 5-HT2A; Receptors, N-Methyl-D-Aspartate; Serotonin; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Tetrodotoxin | 2004 |
Dissociable contribution of 5-HT1A and 5-HT2A receptors in the medial prefrontal cortex to different aspects of executive control such as impulsivity and compulsive perseveration in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Attention; Behavior, Animal; Choice Behavior; Compulsive Behavior; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Fluorobenzenes; Impulsive Behavior; Male; Piperazines; Piperidines; Prefrontal Cortex; Pyridines; Rats; Reaction Time; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Receptors, N-Methyl-D-Aspartate; Serotonin Antagonists; Serotonin Receptor Agonists | 2006 |
Endogenous serotonin and serotonin2C receptors are involved in the ability of M100907 to suppress cortical glutamate release induced by NMDA receptor blockade.
Topics: Animals; Behavior, Animal; Cerebral Cortex; Chromatography, High Pressure Liquid; Ethylamines; Excitatory Amino Acid Antagonists; Fluorobenzenes; Glutamic Acid; Indoles; Male; Microdialysis; Piperazines; Piperidines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2C; Receptors, N-Methyl-D-Aspartate; Serotonin; Serotonin 5-HT2 Receptor Agonists; Serotonin Antagonists; Time Factors | 2009 |
Intracisternal administration of NR2 antagonists attenuates facial formalin-induced nociceptive behavior in rats.
Topics: Animals; Behavior, Animal; Cisterna Magna; Disease Models, Animal; Excitatory Amino Acid Antagonists; Facial Pain; Formaldehyde; Injections; Injections, Subcutaneous; Kynurenic Acid; Male; Memantine; Motor Activity; Nociceptors; Phenols; Piperazines; Piperidines; Pruritus; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Time Factors; Vibrissae | 2010 |
Hippocampal long-term depression is required for the consolidation of spatial memory.
Topics: Animals; CA1 Region, Hippocampal; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; Long-Term Potentiation; Long-Term Synaptic Depression; Male; Maze Learning; Memory; Phenols; Piperazines; Piperidines; Protein Subunits; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spatial Behavior | 2010 |
Opposing synaptic regulation of amyloid-β metabolism by NMDA receptors in vivo.
Topics: Action Potentials; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Analysis of Variance; Animals; Brain Waves; Calcium; Chelating Agents; Dose-Response Relationship, Drug; Egtazic Acid; Electroencephalography; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Excitatory Amino Acid Antagonists; Extracellular Signal-Regulated MAP Kinases; Extracellular Space; Flavones; Humans; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; N-Methylaspartate; Piperazines; Piperidines; Pregnanolone; Presenilin-1; Receptors, N-Methyl-D-Aspartate; Serotonin; Sodium Channel Blockers; Synapses; Tetrodotoxin | 2011 |
Dorsal-striatal 5-HT₂A and 5-HT₂C receptors control impulsivity and perseverative responding in the 5-choice serial reaction time task.
Topics: Animals; Animals, Outbred Strains; Attention; Choice Behavior; Corpus Striatum; Dose-Response Relationship, Drug; Ethylamines; Fluorobenzenes; Impulsive Behavior; Indoles; Male; Microinjections; Piperazines; Piperidines; Prefrontal Cortex; Rats; Reaction Time; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, N-Methyl-D-Aspartate; Serial Learning; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists | 2012 |
Bidirectional modulatory effect of 17β-estradiol on NMDA receptors via ERα and ERβ in the dentate gyrus of juvenile male rats.
Topics: Animals; Dentate Gyrus; Dose-Response Relationship, Drug; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogens; Excitatory Postsynaptic Potentials; Female; Ginsenosides; In Vitro Techniques; Male; NAD; Phenols; Piperazines; Piperidines; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Sapogenins | 2013 |
High-frequency stimulation-induced synaptic potentiation in dorsal and ventral CA1 hippocampal synapses: the involvement of NMDA receptors, mGluR5, and (L-type) voltage-gated calcium channels.
Topics: Animals; CA1 Region, Hippocampal; Calcium Channel Blockers; Calcium Channels, L-Type; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Long-Term Potentiation; Male; Nimodipine; Piperazines; Piperidines; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, N-Methyl-D-Aspartate; Thiazoles | 2016 |