Compounds > 3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid

3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid and n-methylaspartate

3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid has been researched along with n-methylaspartate in 157 studies

Research

Studies (157)

Timeframe	Studies, this research(%)	All Research%
pre-1990	37 (23.57)	18.7374
1990's	93 (59.24)	18.2507
2000's	23 (14.65)	29.6817
2010's	4 (2.55)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bigge, CF; Bobovski, TP; Brahce, LJ; Coughenour, LL; Drummond, JT; Hays, SJ; Johnson, G; Novak, PM; Rice, MJ	1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Hisanaga, K; Sagar, SM; Sharp, FR	1
Ishii, T; Masu, M; Moriyoshi, K; Nakanishi, S; Sugihara, H	1
Giberti, A; Mugnaini, M; Ratti, E; van Amsterdam, FT	1
Ohno, M; Watanabe, S; Yamamoto, T	1
Russo, RE; Velluti, JC	1
Beckstead, RM; Somers, DL	1
Dutton, GR; Rogers, KL	1
French, ED	1
Bullock, R; Inglis, F; Kuroda, Y	1
Aulakh, CS; Hill, JL; Lesch, KP; Murphy, DL; Wolozin, BL	1
Pezzola, A; Sagratella, S; Scotti De Carolis, A; Zeng, YC	1
Crawley, JN; Evers, JR; Paul, SM	1
Abraham, WC; Christie, BR	1
Clark, D; Overton, P	1
Hatziefthimiou, A; Kouvelas, ED; Mitsacos, A; Mitsaki, E; Plaitakis, A	1
Eaton, SA; Roberts, WA; Salt, TE	1
Avoli, M; Hwa, GG	1
Esguerra, M; Kwon, YH; Sur, M	1
Jacocks, HM; McMahon, PN; Werling, LL	1
Berge, OG; Hole, K; Lund, A; Mjellem-Joly, N	1
Bradford, HF; Young, AM	2
Balster, RL; Mansbach, RS	1
Balster, RL; Jortani, SA; Mansbach, RS; Willetts, J	1
Coyne, KE; Farah, JM; Iyengar, S; Mick, SJ; Rao, TS	1
Doudou, N; Kito, S; Miyoshi, R; Nomoto, T	1
Insel, TR; Skolnick, P; Trullas, R; Winslow, JT	1
Benveniste, M; Mayer, ML; Mienville, JM; Sernagor, E	1
Akaike, N; Murase, K; Nakagawa, T; Shirasaki, T; Tateishi, N	1
Ishida, M; Ishihara, T; Nakagawa, Y; Saitoh, K; Shinozaki, H	1
Chaki, S; Muramatsu, M; Otomo, S; Usuki-Ito, C	1
Costa, E; Grayson, DR; Szekely, AM	1
Corbett, R; Cornfeldt, ML; Dunn, RW; Fielding, S; Laws-Ricker, L; Martin, LL; Payack, JF; Rush, DK; Wilmot, CA	1
Hata, N; Nishikawa, T; Takahashi, K; Umino, A	1
Chiamulera, C; Costa, S; Reggiani, A	1
Balster, RL; Tokarz, ME; Willetts, J	1
Avoli, M; Drapeau, C; Louvel, J; Perreault, P; Pumain, R	1
Keith, R; Patel, J; Salama, A; Thompson, C; Zinkand, WC	1
Crain, BJ; Nadler, JV; Neill, KH; Somjen, GG; Urban, L	1
Parada-Turska, J; Turski, WA	1
Kouda, T; Ogawa, Y; Ogita, K; Yoneda, Y	1
Costa, E; Eimerl, S; Schramm, M	1
Dilworth, V; Farah, JM; Iyengar, S; Michel, J; Mick, S; Rao, TS; Wood, PL	1
Meldrum, BS; Swan, JH	1
Honoré, T; Imperato, A; Jensen, LH	1
Abraham, WC; Mason, SE; Ward, L	1
Klockgether, T; Turski, L	1
Darlington, CL; Sansom, AJ; Smith, PF	1
Upchurch, M; Wehner, JM	1
Abraham, WC; Kirk, RC; McNaughton, N; Tan, S	1
Balster, RL; Willetts, J	3
Ross, SM; Roy, DN; Spencer, PS	1
Cler, J; Emmett, MR; Iyengar, S; Mick, S; Rao, TS; Wood, PL	1
Kabuto, H; Mizukawa, K; Mori, A; Yokoi, I	1
Carelli, RM; Jarvis, MF; Liebman, JM; O'Neill, KA	1
D'Angio, M; Scatton, B; Serrano, A	1
Demediuk, P; Faden, AI; Panter, SS; Vink, R	1
Sawyer, BD; Shannon, HE	1
Scherer, WJ; Udin, SB	1
Jackson, A; Sanger, DJ	1
Johnston, MV; McDonald, JW; Silverstein, FS	1
Johnston, MV; McDonald, JW; Roeser, NF; Silverstein, FS	1
Darlington, CL; Smith, PF	2
Jarvis, MF; Murphy, DE; Williams, M	1
Arbilla, S; Benavides, J; Carter, C; Legendre, P; Lloyd, KG; MacKenzie, ET; Noel, F; Thuret, F; Vincent, JD; Zivkovic, B	1
Loo, PS; Sills, MA; Williams, M	1
Davies, J; Evans, RH; Herrling, PL; Jones, AW; Olverman, HJ; Pook, P; Watkins, JC	1
Cotman, CW; Ganong, AH; Harris, EW; Monaghan, DT; Watkins, JC	1
Bennett, DA; Bernard, P; Boehm, C; Lehmann, J; McPherson, S; Murphy, DE; Pastor, G; Schneider, J; Steel, DJ; Tsai, C	1
Childs, AM; Evans, RH; Watkins, JC	1
Davies, SN; Drejer, J; Fletcher, EJ; Honoré, T; Jacobsen, P; Lodge, D; Nielsen, FE	1
Ben-Ari, Y; Cherubini, E; Neuman, R	1
Foster, AC; Gill, R; Woodruff, GN	1
Cotman, CW; Monaghan, DT; Nguyen, L; Olverman, HJ; Watkins, JC	1
Beart, PM; Davies, SN; Jones, MG; Lodge, D; Manallack, DT; Millar, J; Ornstein, PL; Verberne, AJ; Young, N	1
Ben-Ari, Y; Corradetti, R; Gaïarsa, JL	1
Herrling, PL; Klockgether, T; Sontag, KH; Turski, L; Watkins, JC	1
Ho, PM; Tang, AH	1
Hönack, D; Löscher, W; Nolting, B	1
Boast, CA; Etienne, PE; Gerhardt, SC; Lehmann, J; Liebman, JM; Pastor, G	1
Chapman, AG; Meldrum, BS; Nanji, N; Watkins, JC	1
Boast, CA; Pastor, G	1
Liebman, JM; O'Neill, KA	1
Berger, I; Gillis, RA; Kelly, M; Magee, S; McManigle, JE; Norman, WP; Panico, WH; Taveira DaSilva, AM; Vitagliano, S	1
Wu, C	1
Christoffersen, CL; Meltzer, LT	1
Gancher, S; Mayer, A	1
Vornov, JJ	1
Larson, AA; Sun, X	2
Kreeger, JS; Larson, AA	1
Han, D; Ogita, K; Suzuki, T; Yoneda, Y; Zuo, P	1
Burg, M; Horowski, R; Kalveram, KT; Lange, KW; Löschmann, PA; Riederer, P; Sofic, E; Wachtel, H	1
Felix, D; Wang, SR; Wu, GY	1
Amir, S	1
Hirayama, K; Matsuura, S; Murata, R	1
Jarrard, LE; Meldrum, BS	1
Boersma Anderson, CA; Faingold, CL; Naritoku, DK; Randall, ME	1
French, ED; Mura, A; Wang, T	1
Harro, J; Kôks, S; Lang, A; Oöpik, T; Sihver, S; Soosaar, A; Vasar, E; Volke, V	1
Carter, C; Fage, D; Voltz, C	1
Cordery, PM; Smith, AL; Thompson, ID	1
Benardo, LS	1
Bernert, H; Turski, L	1
Alonso, A; Avoli, M; Nagao, T	1
Czuczwar, SJ; Kleinrok, Z; Turski, WA; Tutka, P	1
McCaslin, PP; Oh, S	1
Klockgether, T; Löschmann, PA; Petersen, V; Steinbach, JP; Turski, L; Wüllner, U	1
Bereiter, DA; Bereiter, DF	1
Eblen, F; Klockgether, T; Löschmann, PA; Wüllner, U	1
Lapin, IP	1
Barks, JD; Liu, XH; Silverstein, FS; Sun, R	1
Lapin, IP; Yuwiler, A	1
Janáky, R; Jenei, Z; Oja, SS; Saransaari, P; Varga, V	1
Cory-Slechta, DA	1
Ebert, B; Frølund, B; Jaroszewski, JW; Krogsgaard-Larsen, P; Matzen, L; Stensbøl, TB	1
Cook, JC; Gregg, AE; Sanders, BJ; Soltis, RP	1
Abou-Gharbia, M; Bramlett, DR; Garrison, DT; Kinney, WA; Kowal, DM; Miller, TL; Moyer, JA; Schmid, J; Tasse, RP; Zaleska, MM	1
Baird, DH; Console-Bram, LM; Fitzpatrick-McElligott, SG; McElligott, JG	1
Ikarashi, Y; Ishimaru, H; Maruyama, Y; Shiobara, T; Takahashi, A; Yuzurihara, M	1
Ikarashi, Y; Ishimaru, H; Maruyama, Y; Shiobara, T; Takahashi, A	1
Bittigau, P; Hübner, C; Ikonomidou, C; Ishimaru, MJ; Olney, JW; Pohl, D; Stadthaus, D; Turski, L	1
Binns, KE; Salt, TE; Turner, JP	1
Barks, JD; Silverstein, FS; Wang, P	1
Iravani, MM; Kruk, ZL; Muscat, R	1
Descombes, S; Psarropoulou, C	1
Audinot, V; Bervoets, K; Brocco, M; Honoré, P; Millan, MJ; Veiga, S	1
Fadda, F; Mameli, M; Mancinelli, R; Rossetti, ZL; Vargiu, R	1
Alvarez-Vega, M; Baamonde, A; Gutiérrez, M; Hidalgo, A; Menéndez, L	1
Pollard, M	1
Cobanoğlu, S; Görgülü, A; Kiriş, T; Küçük, M; Turkoğlu, U; Unal, F	1
Mao, L; Wang, JQ	1
Ikonomidou, C; Stefovska, V; Turski, L	1
Eshak, M; Iannotti, F; Pringle, AK; Self, J	1
Brown, RE; Podhorna, J	1
Muller, RU; Quirk, GJ; Santini, E	1
Alcocer, I; Bermúdez-Rattoni, F; Escobar, ML	1
Allgaier, C; Fischer, W; Franke, H; Illes, P; Scheibler, P	1
Frankland, PW; Ohno, M; Silva, AJ	1
Benz, B; Binns, KE; Do, KQ; Eaton, SA; Salt, TE	1
Cory-Slechta, DA; Reeves, R; Thiruchelvam, M	1
Hong, JT; Kim, HC; Kim, HS; Lee, YM; Oh, KW	1
Bennett, S; Gronier, B	1
Dembrow, NC; George, AA; Oestreich, J; Zakon, HH	1
Abdollahi, M; Aliahmadi, A; Bayrami, Z; Hashemi, N; Kebriaeezadeh, A; Khorasani, R; Mohammadirad, A; Nikfar, S; Sharifzadeh, M; Vosough, S	1
Dekundy, A; Kaminski, RM; Turski, WA; Zielinska, E	1
Del Arco, A; Mora, F; Segovia, G	1
Christie, JM; Jahr, CE	1
Gacsályi, I; Kapus, G; Kertész, S; Lévay, G	1
Chevalier, M; Doren, EL; Frim, DM; Koch, H; Kohrman, MH; Lasky, RE; Lew, SM; Marcuccilli, CJ; Mrejeru, A; Peña-Ortega, F; Pytel, P; Ramirez, JM; Tryba, AK; van Drongelen, W; Viemari, JC	1
Cirrito, JR; Goebel, WD; Holtzman, DM; Restivo, JL; Verges, DK	1
Gocel, J; Larson, J	1

Other Studies

157 other study(ies) available for 3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid and n-methylaspartate

Article	Year
New and versatile approaches to the synthesis of CPP-related competitive NMDA antagonists. Preliminary structure-activity relationships and pharmacological evaluation. Journal of medicinal chemistry, 1990, Volume: 33, Issue:10 Topics: Animals; Binding, Competitive; Cerebral Cortex; Chemical Phenomena; Chemistry, Physical; In Vitro Techniques; N-Methylaspartate; Piperazines; Piperidines; Rats; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship; Synaptic Membranes	1990
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
N-methyl-D-aspartate antagonists block fos-like protein expression induced via multiple signaling pathways in cultured cortical neurons. Journal of neurochemistry, 1992, Volume: 58, Issue:5 Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Blotting, Northern; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Fetus; Glutamates; Glutamic Acid; Immunohistochemistry; N-Methylaspartate; Neurons; Piperazines; Proto-Oncogene Proteins c-fos; Signal Transduction	1992
Structures and properties of seven isoforms of the NMDA receptor generated by alternative splicing. Biochemical and biophysical research communications, 1992, Jun-30, Volume: 185, Issue:3 Topics: 2-Amino-5-phosphonovalerate; Amino Acid Sequence; Animals; Base Sequence; Chromosome Deletion; Cloning, Molecular; Dizocilpine Maleate; DNA; Gene Library; Kynurenic Acid; Molecular Sequence Data; N-Methylaspartate; Oocytes; Piperazines; Prosencephalon; Rats; Receptors, N-Methyl-D-Aspartate; Restriction Mapping; RNA Splicing; RNA, Messenger; Xenopus	1992
3-[(+-)-2-carboxypiperazin-4-yl]propyl-1-phosphonic acid recognizes two N-methyl-D-aspartate binding sites in rat cerebral cortex membranes. Journal of neurochemistry, 1992, Volume: 59, Issue:5 Topics: Animals; Binding, Competitive; Cerebral Cortex; Glutamates; Glutamic Acid; Male; N-Methylaspartate; Neurotransmitter Agents; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synaptic Membranes	1992
Effects of intrahippocampal injections of N-methyl-D-aspartate receptor antagonists and scopolamine on working and reference memory assessed in rats by a three-panel runway task. The Journal of pharmacology and experimental therapeutics, 1992, Volume: 263, Issue:3 Topics: 2-Amino-5-phosphonovalerate; Animals; Hippocampus; Male; Memory; N-Methylaspartate; Pipecolic Acids; Piperazines; Rats; Rats, Wistar; Receptors, Muscarinic; Receptors, N-Methyl-D-Aspartate; Scopolamine	1992
Inhibitory effects of excitatory amino acids on pyramidal cells of the in vitro turtle medial cortex. Experimental brain research, 1992, Volume: 92, Issue:1 Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Cerebral Cortex; Electric Stimulation; Electroencephalography; Electrophysiology; gamma-Aminobutyric Acid; In Vitro Techniques; Iontophoresis; Membrane Potentials; N-Methylaspartate; Piperazines; Pyramidal Tracts; Receptors, N-Methyl-D-Aspartate; Synapses; Tetrodotoxin; Turtles	1992
N-methyl-D-aspartate receptor antagonism alters substance P and met5-enkephalin biosynthesis in neurons of the rat striatum. The Journal of pharmacology and experimental therapeutics, 1992, Volume: 262, Issue:2 Topics: Animals; Corpus Striatum; Enkephalin, Methionine; Enkephalins; Male; N-Methylaspartate; Neurons; Piperazines; Protein Precursors; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Substance P; Tachykinins; Valine	1992
Evoked endogenous taurine release from cultured cerebellar neurons. Advances in experimental medicine and biology, 1992, Volume: 315 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Cerebellum; Dizocilpine Maleate; Ibotenic Acid; Kainic Acid; N-Methylaspartate; Neurons; Piperazines; Quinoxalines; Quisqualic Acid; Rats; Receptors, N-Methyl-D-Aspartate; Taurine	1992
Competitive NMDA receptor antagonists attenuate phencyclidine-induced excitations of A10 dopamine neurons. European journal of pharmacology, 1992, Jun-24, Volume: 217, Issue:1 Topics: Action Potentials; Animals; Anticonvulsants; Binding, Competitive; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Male; N-Methylaspartate; Neurons; Phencyclidine; Pipecolic Acids; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Stimulation, Chemical	1992
Glucose hypermetabolism after acute subdural hematoma is ameliorated by a competitive NMDA antagonist. Journal of neurotrauma, 1992,Summer, Volume: 9, Issue:2 Topics: Acute Disease; Animals; Autoradiography; Blood Pressure; Brain Chemistry; Glucose; Hematoma, Subdural; Hippocampus; Male; N-Methylaspartate; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate	1992
3-(2-Carboxypiperazin-4-yl)propyl-1-phosphonic acid decreases NMDA receptor mRNA. European journal of pharmacology, 1992, Sep-01, Volume: 227, Issue:1 Topics: Animals; Base Sequence; Injections, Subcutaneous; Male; Molecular Sequence Data; N-Methylaspartate; Piperazines; Polymerase Chain Reaction; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; RNA, Messenger	1992
Inhibitory influence of morphinans on ictal and interictal EEG changes induced by cortical application of penicillin in rabbits: a comparative study with NMDA antagonists and pentobarbitone. Pharmacology, biochemistry, and behavior, 1992, Volume: 43, Issue:2 Topics: Animals; Behavior, Animal; Cerebral Cortex; Dizocilpine Maleate; Electroencephalography; Injections; Male; Morphinans; N-Methylaspartate; Penicillins; Pentobarbital; Piperazines; Rabbits; Receptors, N-Methyl-D-Aspartate; Seizures	1992
Polyamines inhibit N-methyl-D-aspartate antagonist-induced darting behavior in the rat prefrontal cortex. Brain research, 1992, Jul-17, Volume: 586, Issue:1 Topics: Animals; Behavior, Animal; Frontal Lobe; Injections; Male; Motor Activity; N-Methylaspartate; Piperazines; Polyamines; Putrescine; Rats; Rats, Inbred Strains; Spermidine	1992
NMDA-dependent heterosynaptic long-term depression in the dentate gyrus of anaesthetized rats. Synapse (New York, N.Y.), 1992, Volume: 10, Issue:1 Topics: Analysis of Variance; Anesthesia, General; Animals; Evoked Potentials; Hippocampus; N-Methylaspartate; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Synapses; Time Factors	1992
Iontophoretically administered drugs acting at the N-methyl-D-aspartate receptor modulate burst firing in A9 dopamine neurons in the rat. Synapse (New York, N.Y.), 1992, Volume: 10, Issue:2 Topics: Animals; Dopamine; Dose-Response Relationship, Drug; Evoked Potentials; Iontophoresis; Male; N-Methylaspartate; Neurons; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate	1992
Quantitative autoradiographic study of L-glutamate binding sites in normal and atrophic human cerebellum. Journal of neuroscience research, 1991, Volume: 28, Issue:3 Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adolescent; Adult; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Cerebellum; Female; Glutamates; Glutamic Acid; Humans; Ibotenic Acid; Male; N-Methylaspartate; Olivopontocerebellar Atrophies; Piperazines; Quinoxalines; Quisqualic Acid; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter	1991
Excitatory amino acid receptors mediate synaptic responses to visual stimuli in superior colliculus neurones of the rat. Neuroscience letters, 1991, Aug-19, Volume: 129, Issue:2 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Ibotenic Acid; Iontophoresis; Kainic Acid; N-Methylaspartate; Neurons; Photic Stimulation; Piperazines; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Superior Colliculi; Synapses	1991
The involvement of excitatory amino acids in neocortical epileptogenesis: NMDA and non-NMDA receptors. Experimental brain research, 1991, Volume: 86, Issue:2 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Bicuculline; Cerebral Cortex; Dizocilpine Maleate; Electric Stimulation; Epilepsy; In Vitro Techniques; Male; Membrane Potentials; N-Methylaspartate; Neurons; Piperazines; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate	1991
NMDA and non-NMDA receptors mediate visual responses of neurons in the cat's lateral geniculate nucleus. Journal of neurophysiology, 1991, Volume: 66, Issue:2 Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cats; Electric Stimulation; Evoked Potentials; Geniculate Bodies; Kainic Acid; N-Methylaspartate; Neurons; Piperazines; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synaptic Transmission; Time Factors; Visual Perception	1991
Regulation of [3H]dopamine release from guinea pig striatum by NMDA receptor/channel activators and inhibitors. The Journal of pharmacology and experimental therapeutics, 1990, Volume: 255, Issue:1 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Corpus Striatum; Dopamine; Glycine; Guinea Pigs; Ion Channels; Magnesium; Male; N-Methylaspartate; Piperazines; Pyrrolidines; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid	1990
Potentiation of a behavioural response in mice by spinal coadministration of substance P and excitatory amino acid agonists. Neuroscience letters, 1991, Nov-25, Volume: 133, Issue:1 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Analgesics; Animals; Behavior, Animal; Drug Synergism; Ibotenic Acid; Injections, Spinal; Kainic Acid; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; Nociceptors; Piperazines; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Substance P	1991
N-methyl-D-aspartate releases excitatory amino acids in rat corpus striatum in vivo. Journal of neurochemistry, 1991, Volume: 56, Issue:5 Topics: Amino Acids; Animals; Calcium; Corpus Striatum; Dialysis; Extracellular Space; Magnesium; Male; N-Methylaspartate; Osmolar Concentration; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate	1991
Pharmacological specificity of the phencyclidine discriminative stimulus in rats. Pharmacology, biochemistry, and behavior, 1991, Volume: 39, Issue:4 Topics: Animals; Conditioning, Operant; Discrimination, Psychological; Dose-Response Relationship, Drug; Generalization, Psychological; Ligands; Male; N-Methylaspartate; Pentobarbital; Phencyclidine; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Reinforcement Schedule	1991
NMDA antagonists: lack of antipunishment effect in squirrel monkeys. Pharmacology, biochemistry, and behavior, 1991, Volume: 39, Issue:4 Topics: Amino Acids; Animals; Conditioning, Operant; Isoflurophate; Male; Midazolam; N-Methylaspartate; Pentobarbital; Phencyclidine; Piperazines; Punishment; Receptors, N-Methyl-D-Aspartate; Reinforcement Schedule; Saimiri	1991
N-methyl-D-aspartate treatment increases circulating adrenocorticotropin and luteinizing hormone in the rat. Endocrinology, 1991, Volume: 128, Issue:4 Topics: Adrenocorticotropic Hormone; Animals; beta-Endorphin; Corticosterone; Dexamethasone; Kinetics; Luteinizing Hormone; Male; N-Methylaspartate; Piperazines; Pituitary Gland; Rats; Receptors, N-Methyl-D-Aspartate	1991
Influence of age on N-methyl-D-aspartate antagonist binding sites in the rat brain studied by in vitro autoradiography. Synapse (New York, N.Y.), 1991, Volume: 8, Issue:3 Topics: Aging; Animals; Autoradiography; Brain; Brain Chemistry; In Vitro Techniques; Kinetics; Male; N-Methylaspartate; Piperazines; Rats; Rats, Inbred F344; Receptors, Drug	1991
Rat pup isolation calls are reduced by functional antagonists of the NMDA receptor complex. European journal of pharmacology, 1990, Nov-06, Volume: 190, Issue:1-2 Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Amino Acids, Cyclic; Animals; Female; Glycine; Hippocampus; Kynurenic Acid; Male; N-Methylaspartate; Piperazines; Rats; Rats, Inbred Strains; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Social Isolation; Vocalization, Animal	1990
Concentration-jump experiments with NMDA antagonists in mouse cultured hippocampal neurons. Journal of neurophysiology, 1990, Volume: 63, Issue:6 Topics: 2-Amino-5-phosphonovalerate; Alanine; Animals; Aspartic Acid; Cells, Cultured; Glycine; Hippocampus; Kynurenic Acid; Mice; N-Methylaspartate; Neurons; Osmolar Concentration; Piperazines	1990
Effects of antagonists on N-methyl-D-aspartate response in acutely isolated nucleus tractus solitarii neurons of the rat. Neuroscience letters, 1990, May-31, Volume: 113, Issue:2 Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Dibenzocycloheptenes; Dizocilpine Maleate; In Vitro Techniques; Medulla Oblongata; N-Methylaspartate; Piperazines; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter	1990
(2S,3S,4S) alpha-(carboxycyclopropyl)glycine is a novel agonist of metabotropic glutamate receptors. European journal of pharmacology, 1990, Aug-02, Volume: 184, Issue:1 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids, Dicarboxylic; Animals; Electric Stimulation; Ibotenic Acid; In Vitro Techniques; Inositol Phosphates; Kainic Acid; N-Methylaspartate; Piperazines; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred F344; Receptors, Glutamate; Receptors, Neurotransmitter; Synaptosomes	1990
Differentiation of the active site of minaprine from that of phencyclidine in rat hippocampus. Research communications in chemical pathology and pharmacology, 1990, Volume: 69, Issue:1 Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Animals; Binding Sites; Hippocampus; Ketamine; Male; Membranes; N-Methylaspartate; Phencyclidine; Piperazines; Piperidines; Potassium Channels; Pyridazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate	1990
Transcriptional program coordination by N-methyl-D-aspartate-sensitive glutamate receptor stimulation in primary cultures of cerebellar neurons. Molecular pharmacology, 1990, Volume: 38, Issue:5 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cells, Cultured; Cerebellum; DNA-Binding Proteins; Gene Expression; Immunoblotting; N-Methylaspartate; Neurons; Phencyclidine; Piperazines; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Transcription Factors; Transcription, Genetic	1990
Preclinical anxiolytic profiles of 7189 and 8319, novel non-competitive NMDA antagonists. Progress in clinical and biological research, 1990, Volume: 361 Topics: Aniline Compounds; Animals; Anti-Anxiety Agents; Anticonvulsants; Behavior, Animal; Binding, Competitive; Diazepam; Dizocilpine Maleate; Dose-Response Relationship, Drug; Learning; Male; Mice; N-Methylaspartate; Piperazines; Rats; Rats, Inbred Strains; Seizures; Thiophenes; Tritium; Yohimbine	1990
Evidence for involvement of N-methyl-D-aspartate receptor in tonic inhibitory control of dopaminergic transmission in rat medial frontal cortex. Neuroscience letters, 1990, Nov-27, Volume: 120, Issue:1 Topics: 2-Amino-5-phosphonovalerate; 3,4-Dihydroxyphenylacetic Acid; alpha-Methyltyrosine; Animals; Cerebral Cortex; Dopamine; Glutamine; Infusions, Parenteral; Isomerism; Male; Methyltyrosines; N-Methylaspartate; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Tyrosine 3-Monooxygenase	1990
Effect of NMDA- and strychnine-insensitive glycine site antagonists on NMDA-mediated convulsions and learning. Psychopharmacology, 1990, Volume: 102, Issue:4 Topics: 2-Amino-5-phosphonovalerate; Animals; Dizocilpine Maleate; Injections, Intraventricular; Kynurenic Acid; Learning; Male; Mice; N-Methylaspartate; Piperazines; Receptors, Glycine; Receptors, Neurotransmitter; Seizures; Strychnine	1990
Pentobarbital-like effects of N-methyl-D-aspartate antagonists in mice. Life sciences, 1991, Volume: 48, Issue:18 Topics: Animals; Discrimination, Psychological; Dizocilpine Maleate; Dose-Response Relationship, Drug; Male; Mice; N-Methylaspartate; Pentobarbital; Piperazines	1991
Epileptiform activity induced by low chloride medium in the CA1 subfield of the hippocampal slice. Journal of neurophysiology, 1990, Volume: 64, Issue:6 Topics: Animals; Anticonvulsants; Chlorides; Electric Stimulation; Electrodes; Epilepsy; Evoked Potentials; Hippocampus; In Vitro Techniques; Male; Membrane Potentials; N-Methylaspartate; Piperazines; Pyramidal Tracts; Rats; Rats, Inbred Strains	1990
Role of glycine in the N-methyl-D-aspartate-mediated neuronal cytotoxicity. Journal of neurochemistry, 1990, Volume: 54, Issue:3 Topics: Animals; Aspartic Acid; Cell Survival; Cells, Cultured; Dibenzocycloheptenes; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Synergism; Glycine; Kynurenic Acid; N-Methylaspartate; Neurons; Piperazines; Pyrrolidinones; Serine	1990
Postischemic synaptic excitation and N-methyl-D-aspartate receptor activation in gerbils. Stroke, 1990, Volume: 21, Issue:11 Suppl Topics: Animals; Brain Ischemia; Gerbillinae; Male; Membrane Potentials; N-Methylaspartate; Piperazines; Receptors, N-Methyl-D-Aspartate; Synaptic Membranes	1990
Excitatory amino acid antagonists and memory: effect of drugs acting at N-methyl-D-aspartate receptors in learning and memory tasks. Neuropharmacology, 1990, Volume: 29, Issue:12 Topics: Animals; Avoidance Learning; Dizocilpine Maleate; Male; Memory; Mice; Motor Activity; N-Methylaspartate; Pipecolic Acids; Piperazines; Receptors, N-Methyl-D-Aspartate; Reference Values	1990
Radioligand labeling of N-methyl-D-aspartic acid (NMDA) receptors by [3H](+-)-3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid in brain synaptic membranes treated with Triton X-100. Biochemical pharmacology, 1990, Jan-01, Volume: 39, Issue:1 Topics: Affinity Labels; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Binding, Competitive; Brain; N-Methylaspartate; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synaptic Membranes; Tritium	1990
Serum and depolarizing agents cause acute neurotoxicity in cultured cerebellar granule cells: role of the glutamate receptor responsive to N-methyl-D-aspartate. Proceedings of the National Academy of Sciences of the United States of America, 1990, Volume: 87, Issue:3 Topics: Animals; Anticonvulsants; Aspartic Acid; Blood; Cell Survival; Cells, Cultured; Cerebellum; Culture Media; Cytoplasmic Granules; Dibenzocycloheptenes; Dizocilpine Maleate; Glutamates; N-Methylaspartate; Neuromuscular Depolarizing Agents; Oxadiazoles; Piperazines; Potassium Chloride; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter; Veratridine	1990
Sigma receptors modulate the hypothalamic-pituitary-adrenal (HPA) axis centrally: evidence for a functional interaction with NMDA receptors, in vivo. Neuropharmacology, 1990, Volume: 29, Issue:3 Topics: Adrenocorticotropic Hormone; Animals; Aspartic Acid; Cells, Cultured; Hypothalamo-Hypophyseal System; Male; N-Methylaspartate; Pentazocine; Phenazocine; Piperazines; Pituitary-Adrenal System; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, sigma	1990
Protection by NMDA antagonists against selective cell loss following transient ischaemia. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1990, Volume: 10, Issue:3 Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Brain; Brain Ischemia; Dibenzocycloheptenes; Dizocilpine Maleate; Male; N-Methylaspartate; Neurons; Pipecolic Acids; Piperazines; Piperidines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter	1990
Dopamine release in the nucleus caudatus and in the nucleus accumbens is under glutamatergic control through non-NMDA receptors: a study in freely-moving rats. Brain research, 1990, Oct-22, Volume: 530, Issue:2 Topics: Animals; Behavior, Animal; Caudate Nucleus; Dialysis; Dopamine; Glutamates; Haloperidol; Kainic Acid; Male; N-Methylaspartate; Nucleus Accumbens; Piperazines; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter	1990
Effects of the NMDA antagonists CPP and MK-801 on radial arm maze performance in rats. Pharmacology, biochemistry, and behavior, 1990, Volume: 35, Issue:4 Topics: Animals; Aspartic Acid; Behavior, Animal; Dibenzocycloheptenes; Dizocilpine Maleate; Male; Memory; N-Methylaspartate; Piperazines; Rats; Rats, Inbred Strains; Single-Blind Method	1990
NMDA antagonists potentiate antiparkinsonian actions of L-dopa in monoamine-depleted rats. Annals of neurology, 1990, Volume: 28, Issue:4 Topics: Animals; Dizocilpine Maleate; Drug Synergism; Electromyography; Levodopa; Male; Methyltyrosines; Motor Activity; Muscle Rigidity; N-Methylaspartate; Parkinson Disease; Piperazines; Rats; Rats, Inbred Strains; Reserpine	1990
Intraventricular injection of an N-methyl-D-aspartate antagonist disrupts vestibular compensation. Neuropharmacology, 1990, Volume: 29, Issue:1 Topics: Animals; Aspartic Acid; Eye Movements; Guinea Pigs; Injections, Intraventricular; N-Methylaspartate; Piperazines; Posture; Vestibule, Labyrinth	1990
Effects of N-methyl-D-aspartate antagonism on spatial learning in mice. Psychopharmacology, 1990, Volume: 100, Issue:2 Topics: Animals; Aspartic Acid; Female; Learning; Male; Mice; Mice, Inbred C57BL; N-Methylaspartate; Piperazines; Space Perception	1990
Effects of the NMDA antagonists CPP and MK-801 on delayed conditional discrimination. Psychopharmacology, 1989, Volume: 98, Issue:4 Topics: Animals; Anticonvulsants; Aspartic Acid; Dibenzocycloheptenes; Discrimination, Psychological; Dizocilpine Maleate; Dose-Response Relationship, Drug; Male; N-Methylaspartate; Piperazines; Rats; Rats, Inbred Strains; Stereotyped Behavior	1989
Pentobarbital-like discriminative stimulus effects of N-methyl-D-aspartate antagonists. The Journal of pharmacology and experimental therapeutics, 1989, Volume: 249, Issue:2 Topics: Animals; Aspartic Acid; Dibenzocycloheptenes; Discrimination Learning; Dizocilpine Maleate; Dose-Response Relationship, Drug; Flumazenil; Generalization, Psychological; Male; N-Methylaspartate; Pentobarbital; Phencyclidine; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter	1989
Beta-N-oxalylamino-L-alanine action on glutamate receptors. Journal of neurochemistry, 1989, Volume: 53, Issue:3 Topics: Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids, Diamino; Animals; Aspartic Acid; beta-Alanine; Binding, Competitive; Brain; Cerebellum; Cerebral Cortex; Corpus Striatum; Hippocampus; Ibotenic Acid; Kainic Acid; Male; Mice; N-Methylaspartate; Oxadiazoles; Piperazines; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter; Spinal Cord; Synaptic Membranes; Thiocyanates	1989
In vivo modulation of the N-methyl-D-aspartate receptor complex by D-serine: potentiation of ongoing neuronal activity as evidenced by increased cerebellar cyclic GMP. Journal of neurochemistry, 1989, Volume: 53, Issue:3 Topics: Animals; Aspartic Acid; Cerebellum; Cyclic GMP; Cycloserine; Dibenzocycloheptenes; Dizocilpine Maleate; Male; Mice; N-Methylaspartate; Neurons; Piperazines; Pyrrolidinones; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Serine	1989
Effects of competitive and noncompetitive N-methyl-D-aspartate (NMDA) antagonists in rats trained to discriminate NMDA from saline. The Journal of pharmacology and experimental therapeutics, 1989, Volume: 251, Issue:2 Topics: Amino Acids; Animals; Aspartic Acid; Dibenzocycloheptenes; Discrimination Learning; Dizocilpine Maleate; Dose-Response Relationship, Drug; Male; N-Methylaspartate; Phenazocine; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter	1989
Effects of an N-methyl-D-aspartate receptor agonist and its antagonist CPP on the levels of dopamine and serotonin metabolites in rat striatum collected in vivo by using a brain dialysis technique. Neurochemical research, 1989, Volume: 14, Issue:11 Topics: Animals; Aspartic Acid; Behavior, Animal; Corpus Striatum; Dopamine; Male; N-Methylaspartate; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Serotonin	1989
Hyperactivity induced by N-methyl-d-aspartate injections into nucleus accumbens: lack of evidence for mediation by dopaminergic neurons. Pharmacology, biochemistry, and behavior, 1989, Volume: 34, Issue:4 Topics: Animals; Aspartic Acid; Dopamine; Injections, Intraventricular; Male; Microinjections; Motor Activity; N-Methylaspartate; Neurons; Nucleus Accumbens; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Septal Nuclei	1989
NMDA antagonists block restraint-induced increase in extracellular DOPAC in rat nucleus accumbens. European journal of pharmacology, 1989, Mar-14, Volume: 162, Issue:1 Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic alpha-Antagonists; Animals; Aspartic Acid; Carbolines; Convulsants; Diazepam; Male; N-Methylaspartate; Nucleus Accumbens; Phenylacetates; Piperazines; Piperidines; Rats; Rats, Inbred Strains; Restraint, Physical; Riluzole; Septal Nuclei; Thiazoles	1989
The role of excitatory amino acids and NMDA receptors in traumatic brain injury. Science (New York, N.Y.), 1989, May-19, Volume: 244, Issue:4906 Topics: Animals; Aspartic Acid; Binding, Competitive; Brain; Brain Injuries; Dextrorphan; Glutamates; Glutamic Acid; Magnesium; Magnetic Resonance Spectroscopy; Male; N-Methylaspartate; Phosphates; Phosphocreatine; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter	1989
Glutamate receptors of the N-methyl-D-aspartate subtype in the myenteric plexus of the guinea pig ileum. The Journal of pharmacology and experimental therapeutics, 1989, Volume: 251, Issue:2 Topics: Animals; Aspartic Acid; Dibenzocycloheptenes; Dizocilpine Maleate; Glutamates; Glutamic Acid; Guinea Pigs; Ileum; Magnesium; Male; Muscle Contraction; Myenteric Plexus; N-Methylaspartate; Piperazines; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter	1989
N-methyl-D-aspartate antagonists prevent interaction of binocular maps in Xenopus tectum. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1989, Volume: 9, Issue:11 Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Aspartic Acid; Functional Laterality; N-Methylaspartate; Piperazines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Reference Values; Regression Analysis; Superior Colliculi; Visual Fields; Xenopus	1989
Effects of phencyclidine and other N-methyl-D-aspartate antagonists on the schedule-controlled behavior of rats. The Journal of pharmacology and experimental therapeutics, 1989, Volume: 248, Issue:3 Topics: Animals; Aspartic Acid; Conditioning, Psychological; Dibenzocycloheptenes; Dizocilpine Maleate; Male; N-Methylaspartate; Phenazocine; Phencyclidine; Piperazines; Piperidines; Punishment; Rats; Rats, Inbred Strains; Reinforcement Schedule; Stereoisomerism	1989
Neuroprotective effects of MK-801, TCP, PCP and CPP against N-methyl-D-aspartate induced neurotoxicity in an in vivo perinatal rat model. Brain research, 1989, Jun-19, Volume: 490, Issue:1 Topics: Animals; Aspartic Acid; Brain; Dose-Response Relationship, Drug; Female; Male; N-Methylaspartate; Phencyclidine; Piperazines; Rats; Rats, Inbred Strains	1989
Quantitative assessment of neuroprotection against NMDA-induced brain injury. Experimental neurology, 1989, Volume: 106, Issue:3 Topics: Animals; Aspartic Acid; Brain; Brain Diseases; Choline O-Acetyltransferase; Corpus Striatum; Dibenzocycloheptenes; Dizocilpine Maleate; Dose-Response Relationship, Drug; Female; Ketamine; Male; N-Methylaspartate; Piperazines; Rats; Rats, Inbred Strains; Regression Analysis	1989
The effects of N-methyl-D-aspartate antagonists on the development of vestibular compensation in the guinea pig. European journal of pharmacology, 1989, Dec-19, Volume: 174, Issue:2-3 Topics: Animals; Anticonvulsants; Aspartic Acid; Dibenzocycloheptenes; Dizocilpine Maleate; Ear, Inner; Guinea Pigs; In Vitro Techniques; N-Methylaspartate; Nystagmus, Physiologic; Piperazines; Vestibule, Labyrinth	1989
Quantitative autoradiographic localization of NMDA receptors in rat brain using [3H]CPP: comparison with [3H]TCP binding sites. European journal of pharmacology, 1987, Sep-02, Volume: 141, Issue:1 Topics: Animals; Aspartic Acid; Autoradiography; Brain; Brain Chemistry; In Vitro Techniques; Ligands; Male; N-Methylaspartate; Phencyclidine; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter	1987
Ifenprodil and SL 82.0715 as cerebral anti-ischemic agents. II. Evidence for N-methyl-D-aspartate receptor antagonist properties. The Journal of pharmacology and experimental therapeutics, 1988, Volume: 247, Issue:3 Topics: Animals; Aspartic Acid; Brain Ischemia; Cells, Cultured; Cerebellum; Corpus Striatum; Cyclic GMP; Dopamine; Harmaline; In Vitro Techniques; Mice; N-Methylaspartate; Phencyclidine; Piperazines; Piperidines; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spinal Cord	1988
The NMDA antagonists, CPP and CGS 19755, lack affinity for central benzodiazepine receptors. European journal of pharmacology, 1988, Oct-11, Volume: 155, Issue:1-2 Topics: Animals; Anticonvulsants; Aspartic Acid; Binding, Competitive; Brain; Flunitrazepam; In Vitro Techniques; N-Methylaspartate; Pipecolic Acids; Piperazines; Piperidines; Rats; Receptors, GABA-A	1988
CPP, a new potent and selective NMDA antagonist. Depression of central neuron responses, affinity for [3H]D-AP5 binding sites on brain membranes and anticonvulsant activity. Brain research, 1986, Sep-10, Volume: 382, Issue:1 Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Aspartic Acid; Binding Sites; Brain; Cats; Cell Membrane; Interneurons; Membrane Potentials; Mice; Motor Neurons; N-Methylaspartate; Neurons; Piperazines; Rats; Spinal Cord; Valine	1986
Action of 3-((+/-)-2-carboxypiperazin-4-yl)-propyl-1-phosphonic acid (CPP): a new and highly potent antagonist of N-methyl-D-aspartate receptors in the hippocampus. Brain research, 1986, Sep-10, Volume: 382, Issue:1 Topics: Animals; Aspartic Acid; Cell Membrane; Glutamates; Glutamic Acid; Hippocampus; In Vitro Techniques; Kinetics; N-Methylaspartate; Piperazines; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter	1986
CPP, a selective N-methyl-D-aspartate (NMDA)-type receptor antagonist: characterization in vitro and in vivo. The Journal of pharmacology and experimental therapeutics, 1987, Volume: 240, Issue:3 Topics: Acetylcholine; Animals; Aspartic Acid; Cerebellum; Corpus Striatum; Cyclic GMP; Glutamates; Glutamic Acid; In Vitro Techniques; Kinetics; Male; Mice; Mice, Inbred DBA; N-Methylaspartate; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures	1987
The pharmacological selectivity of three NMDA antagonists. European journal of pharmacology, 1988, Jan-05, Volume: 145, Issue:1 Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Aspartic Acid; Dibenzocycloheptenes; Dizocilpine Maleate; Hexamethonium Compounds; In Vitro Techniques; Motor Neurons; N-Methylaspartate; Norepinephrine; Piperazines; Rats; Serotonin; Synaptic Transmission; Valine	1988
Quinoxalinediones: potent competitive non-NMDA glutamate receptor antagonists. Science (New York, N.Y.), 1988, Aug-05, Volume: 241, Issue:4866 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Binding, Competitive; Cell Membrane; Cerebral Cortex; Ibotenic Acid; Kainic Acid; Ketamine; N-Methylaspartate; Neurons; Piperazines; Quinoxalines; Rats; Receptors, AMPA; Receptors, Drug; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spinal Cord	1988
Epileptiform bursts elicited in CA3 hippocampal neurons by a variety of convulsants are not blocked by N-methyl-D-aspartate antagonists. Brain research, 1988, Sep-06, Volume: 459, Issue:2 Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Convulsants; Hippocampus; In Vitro Techniques; Kainic Acid; Kindling, Neurologic; N-Methylaspartate; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine	1988
Neuroprotective effects of MK-801 in vivo: selectivity and evidence for delayed degeneration mediated by NMDA receptor activation. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1988, Volume: 8, Issue:12 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthesia; Animals; Aspartic Acid; Brain; Dibenzocycloheptenes; Dizocilpine Maleate; Ibotenic Acid; Isoflurane; Kainic Acid; Male; N-Methylaspartate; Nerve Degeneration; Piperazines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Time Factors	1988
Two classes of N-methyl-D-aspartate recognition sites: differential distribution and differential regulation by glycine. Proceedings of the National Academy of Sciences of the United States of America, 1988, Volume: 85, Issue:24 Topics: Animals; Aspartic Acid; Autoradiography; Binding Sites; Brain; Glutamates; Glutamic Acid; Glycine; Male; N-Methylaspartate; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter	1988
A comparison between the in vivo and in vitro activity of five potent and competitive NMDA antagonists. British journal of pharmacology, 1988, Volume: 95, Issue:3 Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Binding, Competitive; In Vitro Techniques; N-Methylaspartate; Neurons; Piperazines; Rats; Reflex; Spine; Valine	1988
D-aminophosphonovaleric acid-sensitive spontaneous giant EPSPs in immature rat hippocampal neurones. European journal of pharmacology, 1988, Sep-13, Volume: 154, Issue:2 Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Electric Stimulation; Hippocampus; In Vitro Techniques; Male; N-Methylaspartate; Neurons; Piperazines; Rats; Synapses; Tetrodotoxin; Valine	1988
Muscle relaxant and anticonvulsant activity of 3-((+/-)-2-carboxypiperazin-4-yl)-propyl-1-phosphonic acid, a novel N-methyl-D-aspartate antagonist, in rodents. Neuroscience letters, 1987, Jan-14, Volume: 73, Issue:2 Topics: Animals; Anticonvulsants; Aspartic Acid; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Kainic Acid; Mice; Muscle Relaxants, Central; N-Methylaspartate; Oxadiazoles; Piperazines; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Reflex; Time Factors	1987
Both competitive and non-competitive antagonists of N-methyl-D-aspartic acid disrupt brightness discrimination in rats. European journal of pharmacology, 1988, Jun-22, Volume: 151, Issue:1 Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Dibenzocycloheptenes; Discrimination, Psychological; Dizocilpine Maleate; Light; Male; N-Methylaspartate; Phencyclidine; Piperazines; Rats; Rats, Inbred F344	1988
The NMDA antagonists MK801 and CPP disrupt compensation for unilateral labyrinthectomy in the guinea pig. Neuroscience letters, 1988, Dec-05, Volume: 94, Issue:3 Topics: Adaptation, Physiological; Afferent Pathways; Animals; Aspartic Acid; Denervation; Dibenzocycloheptenes; Dizocilpine Maleate; Ear, Inner; Guinea Pigs; N-Methylaspartate; Neuronal Plasticity; Nystagmus, Pathologic; Piperazines; Vestibule, Labyrinth	1988
Evaluation of CPP, a selective NMDA antagonist, in various rodent models of epilepsy. Comparison with other NMDA antagonists, and with diazepam and phenobarbital. European journal of pharmacology, 1988, Jul-26, Volume: 152, Issue:1-2 Topics: Amygdala; Animals; Anticonvulsants; Aspartic Acid; Diazepam; Electroshock; Epilepsy; Female; Gerbillinae; Kindling, Neurologic; Male; Mice; N-Methylaspartate; Pentylenetetrazole; Phenobarbital; Piperazines; Psychomotor Performance; Rats; Time Factors	1988
The discriminative stimulus effects of N-methyl-D-aspartate antagonists in phencyclidine-trained rats. Neuropharmacology, 1988, Volume: 27, Issue:12 Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Discrimination, Psychological; Dose-Response Relationship, Drug; Injections, Intraventricular; Male; Methohexital; N-Methylaspartate; Phencyclidine; Piperazines; Rats; Rats, Inbred Strains; Time Factors	1988
The N-methyl-D-aspartate antagonists CGS 19755 and CPP reduce ischemic brain damage in gerbils. Brain research, 1988, Mar-01, Volume: 442, Issue:2 Topics: Animals; Aspartic Acid; Brain; Female; Gerbillinae; Hippocampus; Ischemic Attack, Transient; Motor Activity; N-Methylaspartate; Neurons; Pipecolic Acids; Piperazines; Piperidines	1988
Anticonvulsant action and biochemical effects in DBA/2 mice of CPP (3-((+/-)-2-carboxypiperazin-4-yl)-propyl-1-phosphonate), a novel N-methyl-D-aspartate antagonist. European journal of pharmacology, 1987, Jul-02, Volume: 139, Issue:1 Topics: Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Brain Chemistry; Female; Glucose; Lactates; Lactic Acid; Male; Mice; Mice, Inbred DBA; N-Methylaspartate; Piperazines	1987
Characterization of motor activity patterns induced by N-methyl-D-aspartate antagonists in gerbils. Pharmacology, biochemistry, and behavior, 1987, Volume: 27, Issue:3 Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Dose-Response Relationship, Drug; Electronic Data Processing; Female; Gerbillinae; Ketamine; Motor Activity; N-Methylaspartate; Pipecolic Acids; Piperazines; Piperidines; Time Factors	1987
Unique behavioral effects of the NMDA antagonist, CPP, upon injection into the medial pre-frontal cortex of rats. Brain research, 1987, Dec-01, Volume: 435, Issue:1-2 Topics: Animals; Aspartic Acid; Cerebral Cortex; Cerebral Ventricles; Injections, Intraventricular; Kinetics; Male; Motor Activity; N-Methylaspartate; Piperazines; Rats; Rats, Inbred Strains; Time Factors	1987
NMDA receptors are involved at the ventrolateral nucleus tractus solitarii for termination of inspiration. European journal of pharmacology, 1995, Apr-24, Volume: 277, Issue:2-3 Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Apnea; Blood Pressure; Cats; Female; Heart Rate; Male; Microinjections; N-Methylaspartate; Piperazines; Pulmonary Ventilation; Receptors, N-Methyl-D-Aspartate; Respiration; Solitary Nucleus; Vagotomy	1995
Possible role of glutamatergic neurotransmission in regulating ethanol-evoked brain ascorbate release. Neuroscience letters, 1994, Apr-25, Volume: 171, Issue:1-2 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Ascorbic Acid; Brain Chemistry; Dicarboxylic Acids; Electrophysiology; Ethanol; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Injections, Intraventricular; Kainic Acid; Male; Microelectrodes; N-Methylaspartate; Neostriatum; Piperazines; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission	1994
Evidence for N-methyl-D-aspartate and AMPA subtypes of the glutamate receptor on substantia nigra dopamine neurons: possible preferential role for N-methyl-D-aspartate receptors. Neuroscience, 1995, Volume: 67, Issue:2 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dopamine; Glutamic Acid; Iontophoresis; Male; N-Methylaspartate; Neurons; Piperazines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Substantia Nigra	1995
Sensitization to apomorphine-induced rotational behavior in 6-OHDA-lesioned rats: effects of NMDA antagonists on drug response. Brain research, 1995, Jun-05, Volume: 682, Issue:1-2 Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Dizocilpine Maleate; Dopamine Agonists; Excitatory Amino Acid Antagonists; Male; N-Methylaspartate; Oxidopamine; Piperazines; Rats; Rats, Sprague-Dawley; Rotation; Stereotyped Behavior; Sympathectomy, Chemical	1995
Toxic NMDA-receptor activation occurs during recovery in a tissue culture model of ischemia. Journal of neurochemistry, 1995, Volume: 65, Issue:4 Topics: Animals; Brain Ischemia; Cells, Cultured; Cerebral Cortex; Culture Techniques; Deoxyglucose; Dose-Response Relationship, Drug; Glutamic Acid; L-Lactate Dehydrogenase; N-Methylaspartate; Neurotoxins; Piperazines; Potassium Cyanide; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate	1995
Regulation of sigma activity by the amino-terminus of substance P in the mouse spinal cord: involvement of phencyclidine (PCP) sites not linked to N-methyl-D-aspartate (NMDA) activity. Neuropharmacology, 1993, Volume: 32, Issue:9 Topics: Animals; Behavior, Animal; Dizocilpine Maleate; Drug Synergism; Guanidines; Haloperidol; Injections, Spinal; Kainic Acid; Male; Mice; N-Methylaspartate; Peptide Fragments; Piperazines; Receptors, N-Methyl-D-Aspartate; Receptors, Phencyclidine; Receptors, sigma; Spinal Cord; Substance P; Up-Regulation	1993
Increased N-methyl-D-aspartate (NMDA) activity in the mouse spinal cord following morphine does not mediate opioid withdrawal. Brain research, 1994, Nov-07, Volume: 663, Issue:1 Topics: Analysis of Variance; Animals; Dizocilpine Maleate; Injections, Spinal; Male; Mice; Morphine; N-Methylaspartate; Naloxone; Piperazines; Receptors, N-Methyl-D-Aspartate; Reference Values; Spinal Cord; Stereotyped Behavior; Substance Withdrawal Syndrome	1994
Further evidence for multiple forms of an N-methyl-D-aspartate recognition domain in rat brain using membrane binding techniques. Journal of neurochemistry, 1993, Volume: 61, Issue:5 Topics: 2-Amino-5-phosphonovalerate; 4-Chloromercuribenzenesulfonate; Animals; Brain; Dithionitrobenzoic Acid; Dizocilpine Maleate; Ethylmaleimide; Glutamates; Glutamic Acid; Kinetics; Male; N-Methylaspartate; Piperazines; Rats; Rats, Wistar; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Sulfhydryl Reagents; Synaptic Membranes	1993
The competitive NMDA antagonist CPP protects substantia nigra neurons from MPTP-induced degeneration in primates. Naunyn-Schmiedeberg's archives of pharmacology, 1993, Volume: 348, Issue:6 Topics: Animals; Behavior, Animal; Biogenic Monoamines; Callithrix; Female; Immunohistochemistry; Male; MPTP Poisoning; N-Methylaspartate; Nerve Degeneration; Neurons; Piperazines; Putamen; Receptors, N-Methyl-D-Aspartate; Substantia Nigra; Tyrosine 3-Monooxygenase	1993
Effect of acetylcholine and NMDA on neurones of avian tectum and nucleus isthmi. Neuroreport, 1994, Mar-21, Volume: 5, Issue:7 Topics: Acetylcholine; Animals; Columbidae; Iontophoresis; N-Methylaspartate; Neurons; Piperazines; Reaction Time; Receptors, N-Methyl-D-Aspartate; Tectum Mesencephali; Visual Pathways	1994
N-Methyl-D-aspartate receptor-mediated signaling in the supraoptic nucleus involves activation of a nitric oxide-dependent pathway. Brain research, 1994, May-09, Volume: 645, Issue:1-2 Topics: Animals; Arginine; Calcimycin; Chlorisondamine; Cyclic GMP; Heart Rate; Male; Microinjections; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Piperazines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Supraoptic Nucleus	1994
Effects of an N-methyl-D-aspartate antagonist and a GABAergic antagonist on entorhinal tetanic responses during the early stages of amygdala kindling in rats. Neuroscience research, 1994, Volume: 19, Issue:4 Topics: Amygdala; Animals; Electrophysiology; GABA Antagonists; Kindling, Neurologic; Limbic System; Male; N-Methylaspartate; Picrotoxin; Piperazines; Rats; Receptors, N-Methyl-D-Aspartate; Seizures	1994
N-methyl-D-aspartate releases gamma-aminobutyric acid from rat striatum in vivo: a microdialysis study using a novel preloading method. Journal of neurochemistry, 1993, Volume: 60, Issue:2 Topics: Animals; Aspartic Acid; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Corpus Striatum; Dialysis; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Infusions, Parenteral; Kinetics; Male; N-Methylaspartate; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Time Factors; Tritium	1993
MK-801 and phencyclidine act at phencyclidine sites that are not linked to N-methyl-D-aspartate activity to inhibit behavioral sensitization to kainate. Neuroscience, 1993, Volume: 54, Issue:3 Topics: 2-Amino-5-phosphonovalerate; Animals; Behavior, Animal; Capsaicin; Dizocilpine Maleate; Haloperidol; Kainic Acid; Male; Mice; N-Methylaspartate; Nociceptors; Phencyclidine; Piperazines; Receptors, N-Methyl-D-Aspartate; Receptors, Phencyclidine; Receptors, sigma; Spinal Cord	1993
Selective excitotoxic pathology in the rat hippocampus. Neuropathology and applied neurobiology, 1993, Volume: 19, Issue:5 Topics: Animals; Brain; Brain Damage, Chronic; Cell Death; Hippocampus; Ibotenic Acid; Kainic Acid; Male; N-Methylaspartate; Nerve Degeneration; Neurotoxins; Organ Specificity; Piperazines; Quisqualic Acid; Rats; Rats, Sprague-Dawley	1993
Noncompetitive and competitive NMDA antagonists exert anticonvulsant effects by actions on different sites within the neuronal network for audiogenic seizures. Experimental neurology, 1993, Volume: 119, Issue:2 Topics: Acoustic Stimulation; Animals; Anticonvulsants; Brain; Dizocilpine Maleate; Female; Male; N-Methylaspartate; Nerve Net; Piperazines; Rats; Seizures	1993
MK-801, phencyclidine (PCP), and PCP-like drugs increase burst firing in rat A10 dopamine neurons: comparison to competitive NMDA antagonists. Synapse (New York, N.Y.), 1993, Volume: 13, Issue:2 Topics: Action Potentials; Animals; Dizocilpine Maleate; Dopamine; Dose-Response Relationship, Drug; Illicit Drugs; Male; N-Methylaspartate; Neurons; Phencyclidine; Pipecolic Acids; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Stereotaxic Techniques; Tegmentum Mesencephali; Vibrissae	1993
Anti-exploratory effect of N-methyl-D-aspartate in elevated plus-maze. Involvement of NMDA and CCK receptors. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 1993, Volume: 3, Issue:1 Topics: Analysis of Variance; Animals; Benzodiazepinones; Cerebral Cortex; Cholecystokinin; Devazepide; Dizocilpine Maleate; Exploratory Behavior; Female; Imipramine; Kinetics; Mice; N-Methylaspartate; Phenylurea Compounds; Piperazines; Proglumide; Radioligand Assay; Receptors, Cholecystokinin; Receptors, N-Methyl-D-Aspartate	1993
Ouabain releases striatal polyamines in vivo independently of N-methyl-D-aspartate receptor activation. Journal of neurochemistry, 1993, Volume: 61, Issue:1 Topics: Animals; Corpus Striatum; Dizocilpine Maleate; Male; N-Methylaspartate; Ouabain; Piperazines; Polyamines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spermidine; Spermine	1993
Manufacture and release characteristics of Elvax polymers containing glutamate receptor antagonists. Journal of neuroscience methods, 1995, Volume: 60, Issue:1-2 Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Dizocilpine Maleate; Drug Carriers; Drug Implants; Excitatory Amino Acid Antagonists; Ferrets; Molecular Weight; N-Methylaspartate; Piperazines; Polyvinyls; Receptors, Glutamate	1995
N-methyl-D-aspartate transmission modulates GABAB-mediated inhibition of rat hippocampal pyramidal neurons in vitro. Neuroscience, 1995, Volume: 68, Issue:3 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Antagonists; GABA-B Receptor Antagonists; Glutamic Acid; Hippocampus; In Vitro Techniques; Interneurons; N-Methylaspartate; Organophosphorus Compounds; Patch-Clamp Techniques; Piperazines; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission	1995
Traumatic brain damage prevented by the non-N-methyl-D-aspartate antagonist 2,3-dihydroxy-6-nitro-7-sulfamoylbenzo[f] quinoxaline. Proceedings of the National Academy of Sciences of the United States of America, 1996, May-28, Volume: 93, Issue:11 Topics: Animals; Brain Injuries; Cerebral Cortex; Disease Models, Animal; Excitatory Amino Acid Antagonists; Hippocampus; Humans; Male; N-Methylaspartate; Nerve Degeneration; Neurons; Piperazines; Quinoxalines; Rats; Rats, Inbred F344; Time Factors; Wounds, Nonpenetrating	1996
Epileptiform activity induced by pilocarpine in the rat hippocampal-entorhinal slice preparation. Neuroscience, 1996, Volume: 72, Issue:2 Topics: Animals; Electrophysiology; Entorhinal Cortex; Epilepsy; Excitatory Amino Acid Antagonists; Hippocampus; In Vitro Techniques; Microelectrodes; Muscarinic Agonists; N-Methylaspartate; Pilocarpine; Piperazines; Rats; Rats, Sprague-Dawley	1996
Influence of aminophylline and strychnine on the protective activity of excitatory amino acid antagonists against maximal electroshock-induced convulsions in mice. Journal of neural transmission (Vienna, Austria : 1996), 1996, Volume: 103, Issue:3 Topics: Aminophylline; Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Convulsants; Electroshock; Excitatory Amino Acid Antagonists; Male; Mice; N-Methylaspartate; Phosphodiesterase Inhibitors; Piperazines; Seizures; Strychnine; Valproic Acid	1996
Kainate produces concentration-dependent elevation of glutamate release but not cGMP levels in cultured neuron. General pharmacology, 1996, Volume: 27, Issue:1 Topics: Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Cerebellum; Cyclic GMP; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Kainic Acid; N-Methylaspartate; Neurons; Neurotoxins; Piperazines; Quinoxalines	1996
Effects of the antiparkinsonian drug budipine on central neurotransmitter systems. European journal of pharmacology, 1996, Apr-22, Volume: 301, Issue:1-3 Topics: Animals; Antiparkinson Agents; Biperiden; Central Nervous System; Dopamine; Excitatory Amino Acid Antagonists; Male; Mice; Microdialysis; Muscarinic Antagonists; N-Methylaspartate; Neostriatum; Neurotransmitter Agents; Oxidopamine; Piperazines; Piperidines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Rotation; Seizures; Stereotyped Behavior; Sympatholytics	1996
N-methyl-D-aspartate and non-N-methyl-D-aspartate receptor antagonism reduces Fos-like immunoreactivity in central trigeminal neurons after corneal stimulation in the rat. Neuroscience, 1996, Volume: 73, Issue:1 Topics: Animals; Cornea; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Immunohistochemistry; Injections, Intraventricular; Male; Medulla Oblongata; N-Methylaspartate; Neurons; Nitric Oxide Synthase; Nociceptors; Piperazines; Proto-Oncogene Proteins c-fos; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Solitary Nucleus; Trigeminal Nerve; Trigeminal Nucleus, Spinal	1996
NMDA-mediated toxicity to striatal neurons is not reversed by 7-nitroindazole, an inhibitor of neuronal nitric oxide synthase. Journal of neural transmission. Supplementum, 1995, Volume: 46 Topics: Animals; Corpus Striatum; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Indazoles; Male; N-Methylaspartate; Neurons; Nitric Oxide Synthase; Piperazines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate	1995
Antagonism by CPP (+/-)-3-(2-carboxypiperazin-4-yl)-propyl-1-phosphonic acid, of beta-phenylethylamine (PEA)-induced hypermotility in mice of different strains. Pharmacology, biochemistry, and behavior, 1996, Volume: 55, Issue:2 Topics: Animals; Central Nervous System Stimulants; Dextroamphetamine; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Exploratory Behavior; Injections, Intraventricular; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Motor Activity; N-Methylaspartate; Phenethylamines; Piperazines; Psychotropic Drugs; Receptors, N-Methyl-D-Aspartate; Species Specificity	1996
gp120, a human immunodeficiency virus-1 coat protein, augments excitotoxic hippocampal injury in perinatal rats. Neuroscience, 1997, Volume: 76, Issue:2 Topics: Animals; Animals, Newborn; Autoradiography; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Hippocampus; HIV Envelope Protein gp120; Injections; Male; N-Methylaspartate; Neurotoxins; Piperazines; Pyrrolidinones; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate	1997
Modulation of the inhibitory effect of phenylethylamine on spontaneous motor activity in mice by CPP-(+/-)-3-(2-carboxypiperazin-4-YL)-propyl-1-phosphonic acid. Pharmacology, biochemistry, and behavior, 1997, Volume: 56, Issue:2 Topics: Animals; Brain; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Male; Mice; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Motor Activity; N-Methylaspartate; Phenethylamines; Piperazines; Selegiline	1997
Role of histidyl residues in the binding of ligands to the porcine N-methyl-D-aspartate receptor. Neuroscience letters, 1997, Jun-06, Volume: 228, Issue:2 Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Cerebral Cortex; Diethyl Pyrocarbonate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Histidine; Ionophores; Kainic Acid; Ligands; N-Methylaspartate; Piperazines; Radioligand Assay; Receptors, N-Methyl-D-Aspartate; Swine; Synaptic Membranes; Tritium	1997
Postnatal lead exposure and MK-801 sensitivity. Neurotoxicology, 1997, Volume: 18, Issue:1 Topics: Analysis of Variance; Animals; Animals, Suckling; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Lead Poisoning; Male; N-Methylaspartate; Neuroprotective Agents; Phencyclidine; Piperazines; Rats; Receptors, N-Methyl-D-Aspartate	1997
Bioisosterically modified dipeptide excitatory amino acid receptor antagonists containing 3-oxygenated isothiazole ring systems. Bioorganic & medicinal chemistry, 1997, Volume: 5, Issue:8 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Cerebral Cortex; Corpus Callosum; Dipeptides; Electrophysiology; Excitatory Amino Acid Antagonists; Kainic Acid; Models, Chemical; N-Methylaspartate; Piperazines; Rats; Receptors, AMPA; Stereoisomerism	1997
Interaction of GABA and excitatory amino acids in the basolateral amygdala: role in cardiovascular regulation. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1997, Dec-01, Volume: 17, Issue:23 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amygdala; Animals; Arousal; Bicuculline; Blood Pressure; Dicarboxylic Acids; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Heart Rate; Hemodynamics; Kynurenic Acid; Male; N-Methylaspartate; Neurotransmitter Uptake Inhibitors; Picrotoxin; Piperazines; Pyrrolidines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate	1997
Design and synthesis of [2-(8,9-dioxo-2,6-diazabicyclo[5.2.0]non-1(7)-en-2-yl)-ethyl]phosphonic acid (EAA-090), a potent N-methyl-D-aspartate antagonist, via the use of 3-cyclobutene-1,2-dione as an achiral alpha-amino acid bioisostere. Journal of medicinal chemistry, 1998, Jan-15, Volume: 41, Issue:2 Topics: Animals; Azabicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cyclobutanes; Disease Models, Animal; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Ischemic Attack, Transient; Mice; Models, Chemical; N-Methylaspartate; Organophosphonates; Pipecolic Acids; Piperazines; Rats	1998
Modulation of GAP-43 mRNA by GABA and glutamate in cultured cerebellar granule cells. Brain research, 1998, Feb-09, Volume: 783, Issue:2 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Baclofen; Blotting, Northern; Cells, Cultured; Cerebellum; Cycloleucine; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Agonists; gamma-Aminobutyric Acid; GAP-43 Protein; Gene Expression Regulation, Developmental; Glial Fibrillary Acidic Protein; Glutamic Acid; Immunohistochemistry; In Situ Hybridization; Microtubule-Associated Proteins; Muscimol; N-Methylaspartate; Neurons; Neuroprotective Agents; Piperazines; Rats; Rats, Sprague-Dawley; RNA, Messenger	1998
Direct regulation of acetylcholine release by N-methyl-D-aspartic acid receptors in rat striatum. Brain research, 1998, Jun-08, Volume: 795, Issue:1-2 Topics: Acetylcholine; Animals; Aziridines; Choline; Choline O-Acetyltransferase; Cholinergic Fibers; Corpus Striatum; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Interneurons; Male; N-Methylaspartate; Neuromuscular Blocking Agents; Piperazines; Radioligand Assay; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Tritium	1998
The role of nitric oxide in striatal acetylcholine release induced by N-methyl-D-aspartate. Neurochemistry international, 1998, Volume: 33, Issue:3 Topics: Acetylcholine; Animals; Arginine; Corpus Striatum; Dibutyryl Cyclic GMP; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Male; N-Methylaspartate; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Piperazines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate	1998
N-Methyl-D-aspartate antagonists and apoptotic cell death triggered by head trauma in developing rat brain. Proceedings of the National Academy of Sciences of the United States of America, 1999, Mar-02, Volume: 96, Issue:5 Topics: Animals; Apoptosis; Brain; Brain Injuries; Caudate Nucleus; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Frontal Lobe; Gyrus Cinguli; In Situ Nick-End Labeling; N-Methylaspartate; Nerve Degeneration; Parietal Lobe; Piperazines; Rats; Rats, Wistar; Thalamus; Time Factors	1999
Visual experience alters the molecular profile of NMDA-receptor-mediated sensory transmission. The European journal of neuroscience, 1999, Volume: 11, Issue:3 Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dark Adaptation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; N-Methylaspartate; Neurons, Afferent; Piperazines; Rats; Receptors, N-Methyl-D-Aspartate; Superior Colliculi; Synaptic Transmission; Visual Pathways	1999
Tat, a human immunodeficiency virus-1-derived protein, augments excitotoxic hippocampal injury in neonatal rats. Neuroscience, 1999, Volume: 88, Issue:2 Topics: Animals; Animals, Newborn; Apoptosis; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Gene Products, tat; Hippocampus; HIV Infections; HIV-1; In Situ Nick-End Labeling; Male; N-Methylaspartate; Neurons; Neurotoxins; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; tat Gene Products, Human Immunodeficiency Virus	1999
MK-801 interaction with the 5-HT transporter: a real-time study in brain slices using fast cyclic voltammetry. Synapse (New York, N.Y.), 1999, Jun-01, Volume: 32, Issue:3 Topics: Animals; Carrier Proteins; Dizocilpine Maleate; Dose-Response Relationship, Drug; Electric Stimulation; Fluvoxamine; Half-Life; In Vitro Techniques; Male; Membrane Glycoproteins; Membrane Transport Proteins; Methiothepin; N-Methylaspartate; Nerve Tissue Proteins; Piperazines; Raphe Nuclei; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Serotonin; Serotonin Antagonists; Serotonin Plasma Membrane Transport Proteins; Substantia Nigra	1999
Differential bicuculline-induced epileptogenesis in rat neonatal, juvenile and adult CA3 pyramidal neurons in vitro. Brain research. Developmental brain research, 1999, Oct-20, Volume: 117, Issue:1 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Aging; Animals; Animals, Newborn; Bicuculline; Epilepsy; Excitatory Amino Acid Antagonists; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; N-Methylaspartate; Piperazines; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate	1999
Blockade of NMDA receptors in the nucleus accumbens elicits spontaneous tail-flicks in rats. European journal of pharmacology, 2000, Jan-24, Volume: 388, Issue:1 Topics: Animals; Behavior, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Indoles; Male; Microinjections; N-Methylaspartate; Nucleus Accumbens; Piperazines; Propionates; Rats; Rats, Wistar; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate	2000
Biphasic effects of NMDA on the motility of the rat portal vein. British journal of pharmacology, 2000, Volume: 129, Issue:1 Topics: 2-Amino-5-phosphonovalerate; Animals; Atropine; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; In Vitro Techniques; Male; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth, Vascular; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroprusside; Piperazines; Portal Vein; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin; Vasodilator Agents	2000
Intrathecal N-methyl-D-aspartate (NMDA) induces paradoxical analgesia in the tail-flick test in rats. Pharmacology, biochemistry, and behavior, 2000, Volume: 65, Issue:4 Topics: Analgesics, Non-Narcotic; Animals; Behavior, Animal; Calcium-Transporting ATPases; Calmodulin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Imidazoles; Injections, Spinal; Male; N-Methylaspartate; Naloxone; Narcotic Antagonists; Pain Measurement; Piperazines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Time Factors	2000
Ionotropic glutamate receptor-mediated responses in the rat primary somatosensory cortex evoked by noxious and innocuous cutaneous stimulation in vivo. Experimental brain research, 2000, Volume: 131, Issue:3 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Amino Acid Antagonists; Hot Temperature; Male; N-Methylaspartate; Neurons; Pain; Piperazines; Quinoxalines; Rats; Rats, Wistar; Reaction Time; Receptors, Glutamate; Skin; Somatosensory Cortex; Synapses; Time Factors	2000
Superoxide dismutase activity and the effects of NBQX and CPP on lipid peroxidation in experimental spinal cord injury. Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie, 2000, Volume: 199, Issue:5 Topics: Animals; Excitatory Amino Acid Antagonists; Lipid Peroxidation; Male; Malondialdehyde; N-Methylaspartate; Piperazines; Quinoxalines; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries; Superoxide Dismutase	2000
Motor stimulation following bilateral injection of the group-I metabotropic glutamate receptor agonist into the dorsal striatum of rats: evidence against dependence on ionotropic glutamate receptors. Psychopharmacology, 2000, Volume: 148, Issue:4 Topics: Animals; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Kainic Acid; Male; Microinjections; Motor Activity; N-Methylaspartate; Neostriatum; Neurons; Piperazines; Quinoxalines; Rats; Rats, Wistar; Receptors, Glutamate; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Resorcinols; Stimulation, Chemical	2000
Neuronal death enhanced by N-methyl-D-aspartate antagonists. Proceedings of the National Academy of Sciences of the United States of America, 2000, Nov-07, Volume: 97, Issue:23 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Injuries; Cell Death; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Memantine; N-Methylaspartate; Neurons; Neuroprotective Agents; Neurotoxins; Nitro Compounds; Piperazines; Propionates; Quinoxalines; Rats; Rats, Wistar; Wounds and Injuries	2000
Reducing conditions significantly attenuate the neuroprotective efficacy of competitive, but not other NMDA receptor antagonists in vitro. The European journal of neuroscience, 2000, Volume: 12, Issue:11 Topics: 2-Amino-5-phosphonovalerate; Animals; Dithionitrobenzoic Acid; Dithiothreitol; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Hippocampus; Ischemic Attack, Transient; Memantine; N-Methylaspartate; Neurons; Neuroprotective Agents; Organ Culture Techniques; Piperazines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate	2000
Interactions between N-methyl-D-aspartate and nitric oxide in the modulation of ultrasonic vocalizations of infant rats. European journal of pharmacology, 2000, Nov-24, Volume: 408, Issue:3 Topics: Animals; Animals, Newborn; Arginine; Behavior, Animal; Body Temperature; Drug Interactions; Excitatory Amino Acid Antagonists; Female; Gravity Sensing; Male; Motor Activity; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Piperazines; Rats; Rats, Long-Evans; Ultrasonics; Vocalization, Animal	2000
Consolidation of extinction learning involves transfer from NMDA-independent to NMDA-dependent memory. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2001, Nov-15, Volume: 21, Issue:22 Topics: Amygdala; Animals; Behavior, Animal; Conditioning, Classical; Conditioning, Operant; Excitatory Amino Acid Antagonists; Extinction, Psychological; Fear; Hippocampus; Learning; Long-Term Potentiation; Male; Memory; Mental Recall; N-Methylaspartate; Neuronal Plasticity; Piperazines; Rats; Rats, Sprague-Dawley	2001
In vivo effects of intracortical administration of NMDA and metabotropic glutamate receptors antagonists on neocortical long-term potentiation and conditioned taste aversion. Behavioural brain research, 2002, Feb-01, Volume: 129, Issue:1-2 Topics: 2-Amino-5-phosphonovalerate; Animals; Avoidance Learning; Benzoates; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; Long-Term Potentiation; Male; Microinjections; N-Methylaspartate; Neocortex; Piperazines; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Taste	2002
AMPA-induced Ca(2+) influx in cultured rat cortical nonpyramidal neurones: pharmacological characterization using fura-2 microfluorimetry. European journal of pharmacology, 2002, Mar-01, Volume: 438, Issue:1-2 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Benzothiadiazines; Calcium; Cells, Cultured; Cerebral Cortex; Cobalt; Diazoxide; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Fluorescence; Fluorometry; Fura-2; gamma-Aminobutyric Acid; Immunohistochemistry; N-Methylaspartate; Neurons; Piperazines; Quinoxalines; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate	2002
A pharmacogenetic inducible approach to the study of NMDA/alphaCaMKII signaling in synaptic plasticity. Current biology : CB, 2002, Apr-16, Volume: 12, Issue:8 Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Electrophysiology; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Mice; N-Methylaspartate; Pharmacogenetics; Piperazines; Signal Transduction; Synapses	2002
Release of homocysteic acid from rat thalamus following stimulation of somatosensory afferents in vivo: feasibility of glial participation in synaptic transmission. Neuroscience, 2004, Volume: 124, Issue:2 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Homocysteine; Iontophoresis; Kainic Acid; Male; Methionine; N-Methylaspartate; Neuroglia; Physical Stimulation; Piperazines; Rats; Rats, Wistar; Sulfur Isotopes; Synaptic Transmission; Thalamus; Vibrissae	2004
Development of behavioral sensitization to the cocaine-like fungicide triadimefon is prevented by AMPA, NMDa, DA D1 but not DA D2 receptor antagonists. Toxicological sciences : an official journal of the Society of Toxicology, 2004, Volume: 79, Issue:1 Topics: 3,4-Dihydroxyphenylacetic Acid; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Benzazepines; Brain Chemistry; Corpus Striatum; Drug Administration Schedule; Fungicides, Industrial; Male; Mice; Mice, Inbred C57BL; Motor Activity; N-Methylaspartate; Neuronal Plasticity; Piperazines; Quinoxalines; Receptors, AMPA; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; Remoxipride; Substance Withdrawal Syndrome; Time Factors; Triazoles	2004
The role of nitric oxide on glutaminergic modulation of dopaminergic activation. Pharmacological research, 2005, Volume: 52, Issue:4 Topics: Animals; Apomorphine; Behavior, Animal; Dopamine Agonists; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Male; Mice; Mice, Inbred ICR; Motor Activity; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Penicillamine; Piperazines	2005
Modulation of striatal dopamine release in vitro by agonists of the glycineB site of NMDA receptors; interaction with antipsychotics. European journal of pharmacology, 2005, Dec-19, Volume: 527, Issue:1-3 Topics: Animals; Antipsychotic Agents; Clozapine; Corpus Striatum; Dizocilpine Maleate; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Synergism; Glycine; Haloperidol; Magnesium; Male; N-Methylaspartate; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Salicylamides	2005
A "sample-and-hold" pulse-counting integrator as a mechanism for graded memory underlying sensorimotor adaptation. Neuron, 2006, Feb-16, Volume: 49, Issue:4 Topics: Acclimatization; Action Potentials; Amino Acid Sequence; Animals; Behavior, Animal; Biological Clocks; Calcium; Calcium Channel Blockers; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Electric Fish; Electric Organ; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Flufenamic Acid; In Vitro Techniques; Medulla Oblongata; Memory; Models, Neurological; N-Methylaspartate; Neurons; omega-Conotoxin GVIA; Physical Stimulation; Piperazines; TRPM Cation Channels	2006
Restoration of morphine-induced alterations in rat submandibular gland function by N-methyl-D-aspartate agonist. Acta biologica Hungarica, 2006, Volume: 57, Issue:3 Topics: Analgesics, Opioid; Animals; Calcium; Excitatory Amino Acid Antagonists; Glutamates; Male; Morphine; N-Methylaspartate; Piperazines; Potassium; Rats; Rats, Sprague-Dawley; Saliva; Sodium; Submandibular Gland	2006
NMDA antagonists exert distinct effects in experimental organophosphate or carbamate poisoning in mice. Toxicology and applied pharmacology, 2007, Volume: 219, Issue:2-3 Topics: Animals; Atropine; Carbamates; Cholinesterase Inhibitors; Dichlorvos; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Therapy, Combination; Lethal Dose 50; Male; Mice; N-Methylaspartate; Piperazines; Seizures	2007
Blockade of NMDA receptors in the prefrontal cortex increases dopamine and acetylcholine release in the nucleus accumbens and motor activity. Psychopharmacology, 2008, Volume: 201, Issue:3 Topics: 3,4-Dihydroxyphenylacetic Acid; Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cholinergic Antagonists; Dopamine; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Flupenthixol; Glutamic Acid; Homovanillic Acid; Injections, Intraventricular; Male; Mecamylamine; Microinjections; Motor Activity; Muscarinic Antagonists; N-Methylaspartate; Nicotinic Antagonists; Nucleus Accumbens; Piperazines; Prefrontal Cortex; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; Scopolamine	2008
Selective expression of ligand-gated ion channels in L5 pyramidal cell axons. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2009, Sep-16, Volume: 29, Issue:37 Topics: Animals; Animals, Newborn; Axons; Calcium; Calcium Signaling; Cerebral Cortex; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamates; In Vitro Techniques; Indoles; Ion Channel Gating; Ion Channels; Iontophoresis; Membrane Potentials; N-Methylaspartate; Patch-Clamp Techniques; Piperazines; Pyramidal Cells; Quinoxalines; Rats; Rats, Sprague-Dawley	2009
Deramciclane improves object recognition in rats: potential role of NMDA receptors. Pharmacology, biochemistry, and behavior, 2010, Volume: 94, Issue:4 Topics: Animals; Camphanes; Chickens; Dizocilpine Maleate; Dose-Response Relationship, Drug; Evoked Potentials; Excitatory Amino Acid Antagonists; In Vitro Techniques; Male; Memantine; N-Methylaspartate; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Recognition, Psychology; Retina	2010
Neuronal bursting properties in focal and parafocal regions in pediatric neocortical epilepsy stratified by histology. Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society, 2010, Volume: 27, Issue:6 Topics: Action Potentials; Adolescent; Bicuculline; Child; Child, Preschool; Electric Stimulation; Epilepsy; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; GABA-A Receptor Antagonists; Humans; In Vitro Techniques; Male; N-Methylaspartate; Neocortex; Neurons; Patch-Clamp Techniques; Phosphopyruvate Hydratase; Piperazines	2010
Opposing synaptic regulation of amyloid-β metabolism by NMDA receptors in vivo. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011, Aug-03, Volume: 31, Issue:31 Topics: Action Potentials; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Analysis of Variance; Animals; Brain Waves; Calcium; Chelating Agents; Dose-Response Relationship, Drug; Egtazic Acid; Electroencephalography; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Excitatory Amino Acid Antagonists; Extracellular Signal-Regulated MAP Kinases; Extracellular Space; Flavones; Humans; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; N-Methylaspartate; Piperazines; Piperidines; Pregnanolone; Presenilin-1; Receptors, N-Methyl-D-Aspartate; Serotonin; Sodium Channel Blockers; Synapses; Tetrodotoxin	2011
Synaptic NMDA receptor-mediated currents in anterior piriform cortex are reduced in the adult fragile X mouse. Neuroscience, 2012, Sep-27, Volume: 221 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Bicuculline; Biophysics; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Fragile X Mental Retardation Protein; GABA-A Receptor Antagonists; In Vitro Techniques; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Patch-Clamp Techniques; Piperazines; Prefrontal Cortex; Receptors, N-Methyl-D-Aspartate; Sodium Channel Blockers; Synapses; Tetrodotoxin	2012