3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid has been researched along with glutamic acid in 89 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (8.99) | 18.7374 |
| 1990's | 52 (58.43) | 18.2507 |
| 2000's | 23 (25.84) | 29.6817 |
| 2010's | 6 (6.74) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bramlett, D; Garrison, DT; Kinney, WA; Kowal, DM; Lee, NE; Notvest, RR; Podlesny, EJ; Simmonds, JT; Tasse, RP | 1 |
| Bigge, CF; Drummond, JT; Humblet, C; Johnson, G; Malone, TC; Ortwine, DF; Pinter, GW | 1 |
| Bigge, CF; Bobovski, TP; Brahce, LJ; Coughenour, LL; Drummond, JT; Hays, SJ; Johnson, G; Novak, PM; Rice, MJ | 1 |
| Hisanaga, K; Sagar, SM; Sharp, FR | 1 |
| Molinoff, PB; Powel, RJ; Pullan, LM; Romano, C; Salama, AI; Williams, K | 1 |
| Giberti, A; Mugnaini, M; Ratti, E; van Amsterdam, FT | 1 |
| Clements, JD; Jahr, CE; Lester, RA; Tong, G; Westbrook, GL | 1 |
| Kuramoto, K; Nishimura, S; Sorimachi, M | 1 |
| Monaghan, DT | 1 |
| Hatziefthimiou, A; Kouvelas, ED; Mitsacos, A; Mitsaki, E; Plaitakis, A | 1 |
| Bowen, WD; Reid, AA; Rothman, RB; Setterlund, C | 1 |
| Jeng, YJ; Johnson, KM | 1 |
| Benveniste, M; Mayer, ML | 1 |
| Cunningham, MD; Michaelis, EK | 1 |
| Foucaud, B; Gombos, G | 1 |
| Foye, J; Freed, WJ; Galton, N; Kleinman, JE; Michaelis, EK; Michaelis, ML; Phillips, I | 1 |
| Braunwalder, AF; Jarvis, MF; Loo, PA; Murphy, DE; Sills, MA; Williams, M | 1 |
| Demediuk, P; Faden, AI; Panter, SS; Vink, R | 1 |
| Sawyer, BD; Shannon, HE | 1 |
| Benedict, MS; Fagg, GE; Thedinga, KH | 1 |
| Costa, E; Danysz, W; Fadda, E; Wroblewski, JT | 1 |
| Cotman, CW; Ganong, AH; Harris, EW; Monaghan, DT; Watkins, JC | 1 |
| Bennett, DA; Bernard, P; Boehm, C; Lehmann, J; McPherson, S; Murphy, DE; Pastor, G; Schneider, J; Steel, DJ; Tsai, C | 1 |
| Cotman, CW; Monaghan, DT; Nguyen, L; Olverman, HJ; Watkins, JC | 1 |
| Akaike, A; Kimura, J; Shimohama, S; Tamura, Y; Yokota, T | 1 |
| Wu, C | 1 |
| Christoffersen, CL; Meltzer, LT | 1 |
| Vornov, JJ | 1 |
| Bedingfield, JB; Calder, LD; Karler, R; Thai, LH | 1 |
| Lange, KW; Löschmann, PA; Turski, L; Wachtel, H | 1 |
| Daunais, JB; McGinty, JF; Wang, JQ | 1 |
| Han, D; Ogita, K; Suzuki, T; Yoneda, Y; Zuo, P | 1 |
| Starr, BS; Starr, MS | 1 |
| Costa, E; Kiedrowski, L; Wroblewski, JT | 1 |
| Jayaraman, A; Kiba, H | 1 |
| Camilli, F; Giovannini, MG; Mundula, A; Pepeu, G | 1 |
| Finch, DM; Gigg, J; Tan, AM | 1 |
| Bradford, HF; Young, AM | 1 |
| Baudry, M; Marvizón, JC | 1 |
| Penney, JB; Sakurai, SY; Young, AB | 1 |
| Bowery, NG; Gaviraghi, G; Marien, MR; Ratti, E; Tacconi, S | 1 |
| Foster, AC; Grimwood, S; Wilde, GJ | 1 |
| Han, D; Ogita, K; Yoneda, Y; Zuo, P | 1 |
| DaSilva, AM; Gillis, RA; McManigle, JE; Panico, WH | 1 |
| Benardo, LS | 1 |
| Dixon, JF; Hokin, LE; Los, GV | 1 |
| Barks, JD; Liu, XH; Silverstein, FS; Sun, R | 1 |
| McGinty, JF; Rawls, SM | 1 |
| Betz, H; Hirai, H; Kuhse, J; Laube, B; Sturgess, M | 1 |
| Liu, Y; Souverbie, F; Sundström, E; von Euler, G | 1 |
| Janáky, R; Jenei, Z; Oja, SS; Saransaari, P; Varga, V | 1 |
| Ohno, M; Watanabe, S | 1 |
| Bianchi, L; Giovannelli, L; Giovannini, MG; Kalfin, R; Pepeu, G | 1 |
| Borosky, S; Marcoux, FW; Probert, AW; Taylor, CP | 1 |
| Bird, MM; Owen, AD | 1 |
| Baird, DH; Console-Bram, LM; Fitzpatrick-McElligott, SG; McElligott, JG | 1 |
| Bergles, DE; Jahr, CE | 1 |
| Conti, M; De Luigi, A; De Simoni, MG; Marchesi, F; Moneta, D; Ravizza, T; Vezzani, A | 1 |
| Del Arco, A; Mora, F; Segovia, G | 2 |
| Eaton, MJ; Hake-Frendscho, M; Islam, S; Kumar, KN; Michaelis, EK; Pal, R | 1 |
| Magnusson, KR | 1 |
| Cherubini, E; Gasparini, S; Saviane, C; Voronin, LL | 1 |
| Bell, K; Duffy, P; Kalivas, PW | 1 |
| Dohovics, R; Hermann, A; Janáky, R; Oja, SS; Saransaari, P; Varga, V | 1 |
| Lapierre, L; Massicotte, G; Miceli, D; Valastro, B | 1 |
| Ceccon, M; Rumbaugh, G; Vicini, S | 1 |
| Mora, F; Segovia, G | 1 |
| Moriyama, T; Okuda, K; Sakurada, C; Sakurada, S; Sakurada, T; Sugiyama, A; Tan-No, K; Watanabe, C | 1 |
| Arnth-Jensen, N; Jabaudon, D; Scanziani, M | 1 |
| Kawahara, H; Kawahara, Y; Westerink, BH | 1 |
| Ayala, GX; Tapia, R | 2 |
| Kita, H; Matsui, T | 1 |
| Keller, BU; Körner, R; Stoffel, W; Wachtmann, D | 1 |
| Baviera, M; Calcagno, E; Carli, M; Ceglia, I; Invernizzi, RW; Renoldi, G | 1 |
| Celik, T; Ceyhan, M; Coşar, A; Demirtaş, S; Kayir, H; Uzbay, IT | 1 |
| Barnes, NY; Parent, AT; Sisodia, SS; Taniguchi, Y; Thinakaran, G | 1 |
| Aked, J; Clark, D; Coizet, V; Overton, PG | 1 |
| Calcagno, E; Carli, M; Invernizzi, RW | 1 |
| Cao, P; Wang, SR; Yang, Y | 1 |
| Baviera, M; Calcagno, E; Carli, M; Invernizzi, RW | 1 |
| Kalantzis, G; Kubota, Y; Shouval, HZ | 1 |
| Arnt, J; Calcagno, E; Carli, M; Invernizzi, RW; Mainini, E | 1 |
| Calcagno, E; Carli, M; Invernizzi, RW; Mainini, E; Mainolfi, P | 1 |
| Balducci, C; Baviera, M; Calcagno, E; Carli, M; Invernizzi, RW; Pozzi, L; Sacchetti, G | 1 |
| Appleyard, SM; Cui, RJ; Roberts, BL; Zhao, H; Zhu, M | 1 |
| Augustinaite, S; Heggelund, P; Helm, PJ; Kuhn, B | 1 |
| Avoli, M; Hamidi, S; Herrington, R; Lévesque, M | 1 |
89 other study(ies) available for 3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid and glutamic acid
| Article | Year |
|---|---|
Bioisosteric replacement of the alpha-amino carboxylic acid functionality in 2-amino-5-phosphonopentanoic acid yields unique 3,4-diamino-3-cyclobutene-1,2-dione containing NMDA antagonists.
Topics: 2-Amino-5-phosphonovalerate; Animals; Binding Sites; Carboxylic Acids; Male; Mice; N-Methylaspartate; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Stereoisomerism; Structure-Activity Relationship | 1992 |
Generation of N-methyl-D-aspartate agonist and competitive antagonist pharmacophore models. Design and synthesis of phosphonoalkyl-substituted tetrahydroisoquinolines as novel antagonists.
Topics: Binding, Competitive; Isoquinolines; Models, Molecular; Molecular Conformation; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship | 1992 |
New and versatile approaches to the synthesis of CPP-related competitive NMDA antagonists. Preliminary structure-activity relationships and pharmacological evaluation.
Topics: Animals; Binding, Competitive; Cerebral Cortex; Chemical Phenomena; Chemistry, Physical; In Vitro Techniques; N-Methylaspartate; Piperazines; Piperidines; Rats; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship; Synaptic Membranes | 1990 |
N-methyl-D-aspartate antagonists block fos-like protein expression induced via multiple signaling pathways in cultured cortical neurons.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Blotting, Northern; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Fetus; Glutamates; Glutamic Acid; Immunohistochemistry; N-Methylaspartate; Neurons; Piperazines; Proto-Oncogene Proteins c-fos; Signal Transduction | 1992 |
An antagonist/partial agonist at the polyamine recognition site of the N-methyl-D-aspartate receptor that alters the properties of the glutamate recognition site.
Topics: Animals; Binding Sites; Dizocilpine Maleate; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; Glycine; In Vitro Techniques; Piperazines; Polyamines; Rats; Receptors, N-Methyl-D-Aspartate; Spermine | 1992 |
3-[(+-)-2-carboxypiperazin-4-yl]propyl-1-phosphonic acid recognizes two N-methyl-D-aspartate binding sites in rat cerebral cortex membranes.
Topics: Animals; Binding, Competitive; Cerebral Cortex; Glutamates; Glutamic Acid; Male; N-Methylaspartate; Neurotransmitter Agents; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synaptic Membranes | 1992 |
The time course of glutamate in the synaptic cleft.
Topics: 2-Aminoadipic Acid; Action Potentials; Animals; Cells, Cultured; Glutamates; Glutamic Acid; Hippocampus; Models, Neurological; Neurons; Neurotransmitter Agents; Piperazines; Rats; Receptors, N-Methyl-D-Aspartate; Synapses; Time Factors | 1992 |
Receptor types mediating the rise in the cytosolic free calcium concentration by L-aspartate and L-glutamate in immature cerebellar neurons with N-methyl-D-aspartate receptors.
Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Aspartic Acid; Calcium; Cerebellum; Cytosol; Dizocilpine Maleate; Glutamates; Glutamic Acid; Kinetics; Magnesium; Neurons; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate | 1991 |
Differential stimulation of [3H]MK-801 binding to subpopulations of NMDA receptors.
Topics: Animals; Autoradiography; Brain Chemistry; Cerebral Cortex; Corpus Striatum; Dizocilpine Maleate; Glutamates; Glutamic Acid; In Vitro Techniques; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Thalamus; Valine | 1991 |
Quantitative autoradiographic study of L-glutamate binding sites in normal and atrophic human cerebellum.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adolescent; Adult; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Cerebellum; Female; Glutamates; Glutamic Acid; Humans; Ibotenic Acid; Male; N-Methylaspartate; Olivopontocerebellar Atrophies; Piperazines; Quinoxalines; Quisqualic Acid; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1991 |
The competitive NMDA receptor antagonist, CPP, allosterically modulates NMDA receptor associated PCP binding sites in the absence of steric hinderance.
Topics: Animals; Dizocilpine Maleate; Glutamates; Glutamic Acid; Guinea Pigs; In Vitro Techniques; Kinetics; Membranes; Molecular Conformation; Phencyclidine; Piperazines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Receptors, Phencyclidine | 1990 |
Pharmacological evidence for N-methyl-D-aspartate receptors on nigrostriatal dopaminergic nerve terminals.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Corpus Striatum; Dopamine; Female; Glutamates; Glutamic Acid; Glycine; In Vitro Techniques; Magnesium; Nerve Endings; Phencyclidine; Piperazines; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Substantia Nigra; Synaptosomes; Tetrodotoxin | 1991 |
Kinetic analysis of antagonist action at N-methyl-D-aspartic acid receptors. Two binding sites each for glutamate and glycine.
Topics: 2-Amino-5-phosphonovalerate; Animals; Binding Sites; Biophysical Phenomena; Biophysics; Cells, Cultured; Glutamates; Glutamic Acid; Glycine; Hippocampus; Ion Channels; Kinetics; Kynurenic Acid; Models, Neurological; Piperazines; Receptors, N-Methyl-D-Aspartate | 1991 |
Solubilization and partial purification of 3-((+-)-2-carboxypiperazine-4-yl)-[1,2-3H]propyl-1-phosphonic acid recognition proteins from rat brain synaptic membranes.
Topics: Animals; Brain Chemistry; Cholic Acids; Chromatography, Affinity; Edetic Acid; Glutamates; Glutamic Acid; Glycine; Ibotenic Acid; Magnesium; Male; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Solubility; Synaptic Membranes | 1990 |
Identification and characterization of a high-affinity glutamate-controlled TCP binding site in rat brain postsynaptic densities.
Topics: Animals; Brain; Cell Membrane; Dizocilpine Maleate; Glutamates; Glutamic Acid; In Vitro Techniques; Kinetics; Phencyclidine; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Receptors, Phencyclidine; Subcellular Fractions; Synapses; Synaptosomes | 1990 |
Glutamate receptor changes in brain synaptic membranes from human alcoholics.
Topics: Alcoholism; Glutamates; Glutamic Acid; Hippocampus; Humans; Piperazines; Radioligand Assay; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synaptic Membranes | 1990 |
The N-methyl-D-aspartate receptor complex.
Topics: Anesthetics, Dissociative; Animals; Cerebral Cortex; Glutamates; Glutamic Acid; Ion Channels; Magnesium; Models, Biological; Phencyclidine; Piperazines; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Receptors, Phencyclidine | 1988 |
The role of excitatory amino acids and NMDA receptors in traumatic brain injury.
Topics: Animals; Aspartic Acid; Binding, Competitive; Brain; Brain Injuries; Dextrorphan; Glutamates; Glutamic Acid; Magnesium; Magnetic Resonance Spectroscopy; Male; N-Methylaspartate; Phosphates; Phosphocreatine; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1989 |
Glutamate receptors of the N-methyl-D-aspartate subtype in the myenteric plexus of the guinea pig ileum.
Topics: Animals; Aspartic Acid; Dibenzocycloheptenes; Dizocilpine Maleate; Glutamates; Glutamic Acid; Guinea Pigs; Ileum; Magnesium; Male; Muscle Contraction; Myenteric Plexus; N-Methylaspartate; Piperazines; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1989 |
The N-methyl-D-aspartate (NMDA) receptor complex: a stoichiometric analysis of radioligand binding domains.
Topics: Animals; Binding Sites; Dibenzocycloheptenes; Dizocilpine Maleate; Glutamates; Glutamic Acid; Glycine; Kinetics; Piperazines; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synaptic Membranes; Telencephalon; Tritium | 1989 |
Different modes of action of 3-amino-1-hydroxy-2-pyrrolidone (HA-966) and 7-chlorokynurenic acid in the modulation of N-methyl-D-aspartate-sensitive glutamate receptors.
Topics: Animals; Dibenzocycloheptenes; Dizocilpine Maleate; Glutamates; Glutamic Acid; Glycine; In Vitro Techniques; Kynurenic Acid; Piperazines; Protein Conformation; Pyrrolidinones; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1989 |
Action of 3-((+/-)-2-carboxypiperazin-4-yl)-propyl-1-phosphonic acid (CPP): a new and highly potent antagonist of N-methyl-D-aspartate receptors in the hippocampus.
Topics: Animals; Aspartic Acid; Cell Membrane; Glutamates; Glutamic Acid; Hippocampus; In Vitro Techniques; Kinetics; N-Methylaspartate; Piperazines; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1986 |
CPP, a selective N-methyl-D-aspartate (NMDA)-type receptor antagonist: characterization in vitro and in vivo.
Topics: Acetylcholine; Animals; Aspartic Acid; Cerebellum; Corpus Striatum; Cyclic GMP; Glutamates; Glutamic Acid; In Vitro Techniques; Kinetics; Male; Mice; Mice, Inbred DBA; N-Methylaspartate; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures | 1987 |
Two classes of N-methyl-D-aspartate recognition sites: differential distribution and differential regulation by glycine.
Topics: Animals; Aspartic Acid; Autoradiography; Binding Sites; Brain; Glutamates; Glutamic Acid; Glycine; Male; N-Methylaspartate; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1988 |
Nicotine-induced protection of cultured cortical neurons against N-methyl-D-aspartate receptor-mediated glutamate cytotoxicity.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Glutamates; Glutamic Acid; Nerve Degeneration; Neurons; Nicotine; Parasympathetic Nervous System; Parasympathomimetics; Piperazines; Rats; Receptors, N-Methyl-D-Aspartate | 1994 |
Possible role of glutamatergic neurotransmission in regulating ethanol-evoked brain ascorbate release.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Ascorbic Acid; Brain Chemistry; Dicarboxylic Acids; Electrophysiology; Ethanol; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Injections, Intraventricular; Kainic Acid; Male; Microelectrodes; N-Methylaspartate; Neostriatum; Piperazines; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 1994 |
Evidence for N-methyl-D-aspartate and AMPA subtypes of the glutamate receptor on substantia nigra dopamine neurons: possible preferential role for N-methyl-D-aspartate receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dopamine; Glutamic Acid; Iontophoresis; Male; N-Methylaspartate; Neurons; Piperazines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Substantia Nigra | 1995 |
Toxic NMDA-receptor activation occurs during recovery in a tissue culture model of ischemia.
Topics: Animals; Brain Ischemia; Cells, Cultured; Cerebral Cortex; Culture Techniques; Deoxyglucose; Dose-Response Relationship, Drug; Glutamic Acid; L-Lactate Dehydrogenase; N-Methylaspartate; Neurotoxins; Piperazines; Potassium Cyanide; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1995 |
The dopaminergic, glutamatergic, GABAergic bases for the action of amphetamine and cocaine.
Topics: Amphetamine; Animals; Bicuculline; Cocaine; Dopamine Agonists; GABA Agonists; Glutamic Acid; Male; Mice; Mice, Inbred Strains; Movement; Neostriatum; Piperazines; Stereotyped Behavior; Sulpiride | 1995 |
MPTP-induced degeneration: interference with glutamatergic toxicity.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Chromatography, High Pressure Liquid; Dopamine; Glutamic Acid; Male; Mice; Mice, Inbred C57BL; Nerve Degeneration; Piperazines; Receptors, N-Methyl-D-Aspartate; Serotonin | 1994 |
NMDA receptors mediate amphetamine-induced upregulation of zif/268 and preprodynorphin mRNA expression in rat striatum.
Topics: Animals; Behavior, Animal; Dextroamphetamine; Dizocilpine Maleate; Dynorphins; Gene Expression; Glutamic Acid; Image Processing, Computer-Assisted; In Situ Hybridization; Male; Neostriatum; Neurons; Piperazines; Protein Precursors; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Up-Regulation | 1994 |
Further evidence for multiple forms of an N-methyl-D-aspartate recognition domain in rat brain using membrane binding techniques.
Topics: 2-Amino-5-phosphonovalerate; 4-Chloromercuribenzenesulfonate; Animals; Brain; Dithionitrobenzoic Acid; Dizocilpine Maleate; Ethylmaleimide; Glutamates; Glutamic Acid; Kinetics; Male; N-Methylaspartate; Piperazines; Rats; Rats, Wistar; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Sulfhydryl Reagents; Synaptic Membranes | 1993 |
Glutamate-dopamine interactions in the production of pilocarpine motor seizures in the mouse.
Topics: 2-Amino-5-phosphonovalerate; 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Dizocilpine Maleate; Dopamine Agents; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Mice; Mice, Inbred Strains; Pilocarpine; Piperazines; Pyrrolidinones; Quinoxalines; Receptors, AMPA; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; Seizures | 1993 |
Intracellular sodium concentration in cultured cerebellar granule cells challenged with glutamate.
Topics: Animals; Calcium; Cells, Cultured; Cerebellum; Glutamates; Glutamic Acid; Glycine; Homeostasis; Kinetics; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sodium | 1994 |
Nicotine induced c-fos expression in the striatum is mediated mostly by dopamine D1 receptor and is dependent on NMDA stimulation.
Topics: Animals; Benzamides; Benzazepines; Clozapine; Corpus Striatum; Dizocilpine Maleate; Gene Expression Regulation; Genes, fos; Glutamates; Glutamic Acid; Male; Mecamylamine; Nicotine; Nucleus Accumbens; Piperazines; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Receptors, N-Methyl-D-Aspartate; Reward | 1994 |
Glutamatergic regulation of acetylcholine output in different brain regions: a microdialysis study in the rat.
Topics: Acetylcholine; Animals; Brain Chemistry; Cerebral Cortex; Chromatography, High Pressure Liquid; Electrochemistry; Glutamic Acid; Male; Microdialysis; Neostriatum; Neurons; Piperazines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 1994 |
Glutamatergic hippocampal formation projections to prefrontal cortex in the rat are regulated by GABAergic inhibition and show convergence with glutamatergic projections from the limbic thalamus.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Baclofen; Bicuculline; Brain Mapping; Electric Stimulation; Electrophysiology; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Limbic System; Male; Neurons; Organophosphorus Compounds; Piperazines; Prefrontal Cortex; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Thalamus | 1994 |
N-methyl-D-aspartate releases gamma-aminobutyric acid from rat striatum in vivo: a microdialysis study using a novel preloading method.
Topics: Animals; Aspartic Acid; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Corpus Striatum; Dialysis; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Infusions, Parenteral; Kinetics; Male; N-Methylaspartate; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Time Factors; Tritium | 1993 |
NMDA receptor activation by spermine requires glutamate but not glycine.
Topics: Animals; Dizocilpine Maleate; Glutamates; Glutamic Acid; Glycine; Kynurenic Acid; Male; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spermine | 1993 |
Regionally distinct N-methyl-D-aspartate receptors distinguished by quantitative autoradiography of [3H]MK-801 binding in rat brain.
Topics: Animals; Autoradiography; Brain; Dizocilpine Maleate; Glutamates; Glutamic Acid; Glycine; Kinetics; Kynurenic Acid; Male; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Tissue Distribution; Tritium | 1993 |
Inhibition of [3H]-(+)-MK 801 binding to rat brain sections by CPP and 7-chlorokynurenic acid: an autoradiographic analysis.
Topics: Animals; Autoradiography; Brain; Cerebellum; Dizocilpine Maleate; Glutamates; Glutamic Acid; Glycine; Image Processing, Computer-Assisted; In Vitro Techniques; Kynurenic Acid; Male; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1993 |
Interactions between the glutamate and glycine recognition sites of the N-methyl-D-aspartate receptor from rat brain, as revealed from radioligand binding studies.
Topics: Aminoquinolines; Animals; Binding Sites; Brain; Glutamates; Glutamic Acid; Glycine; Ligands; Pipecolic Acids; Piperazines; Radioligand Assay; Rats; Receptors, N-Methyl-D-Aspartate | 1993 |
Comparative studies on binding of 3 different ligands to the N-methyl-D-aspartate recognition domain in brain synaptic membranes treated with Triton X-100.
Topics: 2-Amino-5-phosphonovalerate; Animals; Binding, Competitive; Brain Chemistry; Detergents; Glutamates; Glutamic Acid; In Vitro Techniques; Male; Octoxynol; Piperazines; Polyethylene Glycols; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Synaptic Membranes | 1993 |
Respiratory effects produced by microinjection of L-glutamate and an uptake inhibitor of L-glutamate into the caudal subretrofacial area of the medulla.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Apnea; Blood Pressure; Cats; Cycloleucine; Dicarboxylic Acids; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Heart Rate; Kynurenic Acid; Male; Neurotoxins; Neurotransmitter Uptake Inhibitors; Piperazines; Pyrrolidines; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Respiration; Respiratory Function Tests; Tidal Volume; Trigeminal Caudal Nucleus | 1995 |
N-methyl-D-aspartate transmission modulates GABAB-mediated inhibition of rat hippocampal pyramidal neurons in vitro.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Antagonists; GABA-B Receptor Antagonists; Glutamic Acid; Hippocampus; In Vitro Techniques; Interneurons; N-Methylaspartate; Organophosphorus Compounds; Patch-Clamp Techniques; Piperazines; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 1995 |
A novel action of lithium: stimulation of glutamate release and inositol 1,4,5 trisphosphate accumulation via activation of the N-methyl D-aspartate receptor in monkey and mouse cerebral cortex slices.
Topics: Animals; Calcium Channels; Cerebral Cortex; Cyclopentanes; Excitatory Amino Acid Antagonists; Glutamic Acid; Haplorhini; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Lithium; Mice; Piperazines; Receptors, Cytoplasmic and Nuclear; Receptors, N-Methyl-D-Aspartate; Valproic Acid | 1996 |
gp120, a human immunodeficiency virus-1 coat protein, augments excitotoxic hippocampal injury in perinatal rats.
Topics: Animals; Animals, Newborn; Autoradiography; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Hippocampus; HIV Envelope Protein gp120; Injections; Male; N-Methylaspartate; Neurotoxins; Piperazines; Pyrrolidinones; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1997 |
L-trans-pyrrolidine-2,4-dicarboxylic acid-evoked striatal glutamate levels are attenuated by calcium reduction, tetrodotoxin, and glutamate receptor blockade.
Topics: Animals; Calcium; Chromatography, High Pressure Liquid; Dicarboxylic Acids; Excitatory Amino Acid Antagonists; Glutamic Acid; Isoquinolines; Male; Microdialysis; Neostriatum; Neurotransmitter Uptake Inhibitors; Oxidation-Reduction; Piperazines; Pyrrolidines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Tetrazoles; Tetrodotoxin | 1997 |
Molecular determinants of agonist discrimination by NMDA receptor subunits: analysis of the glutamate binding site on the NR2B subunit.
Topics: 2-Amino-5-phosphonovalerate; Amino Acid Sequence; Binding Sites; Excitatory Amino Acid Agonists; Glutamic Acid; Glycine; Ion Channel Gating; Models, Molecular; Molecular Sequence Data; Piperazines; Receptors, N-Methyl-D-Aspartate; Sequence Alignment; Sequence Homology, Amino Acid | 1997 |
Unique properties of [3H]MK-801 binding in membranes from the rat spinal cord.
Topics: Animals; Binding, Competitive; Cerebral Cortex; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Male; Membranes; Piperazines; Quinolones; Rats; Rats, Sprague-Dawley; Spinal Cord; Tritium | 1997 |
Role of histidyl residues in the binding of ligands to the porcine N-methyl-D-aspartate receptor.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Cerebral Cortex; Diethyl Pyrocarbonate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Histidine; Ionophores; Kainic Acid; Ligands; N-Methylaspartate; Piperazines; Radioligand Assay; Receptors, N-Methyl-D-Aspartate; Swine; Synaptic Membranes; Tritium | 1997 |
Differential effects of 5-HT3 receptor antagonism on working memory failure due to deficiency of hippocampal cholinergic and glutamatergic transmission in rats.
Topics: Acetylcholine; Animals; Bridged Bicyclo Compounds, Heterocyclic; Conditioning, Psychological; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Male; Memory; Muscarinic Antagonists; Oxazines; Piperazines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Scopolamine; Serotonin Antagonists; Synaptic Transmission | 1997 |
Glutamatergic modulation of cortical acetylcholine release in the rat: a combined in vivo microdialysis, retrograde tracing and immunohistochemical study.
Topics: Acetylcholine; Animals; Excitatory Amino Acid Antagonists; Fluorescent Dyes; GABA Agonists; Glutamic Acid; Immunohistochemistry; Injections, Intraventricular; Male; Microdialysis; Muscimol; Parietal Lobe; Piperazines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Stilbamidines | 1997 |
Sodium channel modulators prevent oxygen and glucose deprivation injury and glutamate release in rat neocortical cultures.
Topics: Animals; Calcium; Cell Death; Cell Hypoxia; Cells, Cultured; Cerebral Cortex; Excitatory Amino Acid Antagonists; Glucose; Glutamic Acid; L-Lactate Dehydrogenase; Lidocaine; Neurons; Phenytoin; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sodium Channel Blockers; Tetrodotoxin | 1997 |
Role of glutamate in the regulation of the outgrowth and motility of neurites from mouse spinal cord neurons in culture.
Topics: Animals; Cell Movement; Cells, Cultured; Excitatory Amino Acid Antagonists; Glutamic Acid; Mice; Microscopy, Video; Neurites; Piperazines; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1997 |
Modulation of GAP-43 mRNA by GABA and glutamate in cultured cerebellar granule cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Baclofen; Blotting, Northern; Cells, Cultured; Cerebellum; Cycloleucine; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Agonists; gamma-Aminobutyric Acid; GAP-43 Protein; Gene Expression Regulation, Developmental; Glial Fibrillary Acidic Protein; Glutamic Acid; Immunohistochemistry; In Situ Hybridization; Microtubule-Associated Proteins; Muscimol; N-Methylaspartate; Neurons; Neuroprotective Agents; Piperazines; Rats; Rats, Sprague-Dawley; RNA, Messenger | 1998 |
Glial contribution to glutamate uptake at Schaffer collateral-commissural synapses in the hippocampus.
Topics: Amino Acid Transport System X-AG; Animals; Astrocytes; ATP-Binding Cassette Transporters; Biological Transport; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; Male; Membrane Potentials; Nerve Fibers; Patch-Clamp Techniques; Piperazines; Pyramidal Cells; Quinoxalines; Rats; Rats, Sprague-Dawley; Synapses; Temperature | 1998 |
Interleukin-1beta immunoreactivity and microglia are enhanced in the rat hippocampus by focal kainate application: functional evidence for enhancement of electrographic seizures.
Topics: Animals; Antibodies; Anticonvulsants; Antirheumatic Agents; Bicuculline; Cell Count; Electroencephalography; Enzyme-Linked Immunosorbent Assay; Epilepsy; Excitatory Amino Acid Agonists; GABA Antagonists; Glutamic Acid; Hippocampus; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Kainic Acid; Male; Microglia; Nerve Degeneration; Neurons; Piperazines; Rats; Rats, Sprague-Dawley; Sialoglycoproteins | 1999 |
Role of glutamate receptors and glutamate transporters in the regulation of the glutamate-glutamine cycle in the awake rat.
Topics: Amino Acid Transport System X-AG; Animals; ATP-Binding Cassette Transporters; Dicarboxylic Acids; Excitatory Amino Acid Antagonists; Glutamic Acid; Glutamine; Male; Piperazines; Pyrrolidines; Quinoxalines; Rats; Rats, Wistar; Receptors, Glutamate | 1999 |
Immunocytochemical and in situ hybridization studies of the expression and distribution of three subunits of a complex with N-methyl-D-aspartate receptor-like properties.
Topics: Animals; Brain; Carrier Proteins; Glutamic Acid; Immunohistochemistry; In Situ Hybridization; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Tissue Distribution | 1999 |
Declines in mRNA expression of different subunits may account for differential effects of aging on agonist and antagonist binding to the NMDA receptor.
Topics: Aging; Animals; Binding, Competitive; Brain Chemistry; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Gene Expression; Glutamic Acid; In Situ Hybridization; Male; Mice; Mice, Inbred C57BL; Piperazines; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Tritium | 2000 |
Silent synapses in the developing hippocampus: lack of functional AMPA receptors or low probability of glutamate release?
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Benzothiadiazines; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; In Vitro Techniques; Mossy Fibers, Hippocampal; Piperazines; Probability; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Temperature | 2000 |
Context-specific enhancement of glutamate transmission by cocaine.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Brain Chemistry; Cocaine; Excitatory Amino Acid Antagonists; Extracellular Space; Glutamic Acid; Male; Microdialysis; Microinjections; Neurotransmitter Agents; Nucleus Accumbens; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Stimulation, Chemical; Synaptic Transmission | 2000 |
Interference of S-nitrosoglutathione with the binding of ligands to ionotropic glutamate receptors in pig cerebral cortical synaptic membranes.
Topics: Alanine; Animals; Binding, Competitive; Cerebral Cortex; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glutathione; Kainic Acid; Kinetics; Ligands; Neuroprotective Agents; Nitroso Compounds; Piperazines; Pyrimidinones; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; S-Nitrosoglutathione; Swine; Synaptic Membranes; Uracil | 2000 |
AMPA receptor modulation in previously frozen mouse brain sections: opposite effects of calcium in the cortex and hippocampus.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arachidonate Lipoxygenases; Arachidonic Acid; Autoradiography; Binding, Competitive; Calcium; Cerebral Cortex; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Flavanones; Flavonoids; Freezing; Glutamic Acid; Hippocampus; Mice; Neuronal Plasticity; Phospholipases A; Piperazines; Prostaglandin Antagonists; Receptors, AMPA; Tritium | 2000 |
Distinct effect of pregnenolone sulfate on NMDA receptor subtypes.
Topics: Animals; Animals, Newborn; Bicuculline; Cell Line; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Membrane Potentials; Neurons; Patch-Clamp Techniques; Piperazines; Pregnenolone; Protein Subunits; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Time Factors | 2001 |
Involvement of NMDA and AMPA/kainate receptors in the effects of endogenous glutamate on extracellular concentrations of dopamine and GABA in the nucleus accumbens of the awake rat.
Topics: Animals; Dicarboxylic Acids; Dopamine; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Male; Neurotransmitter Uptake Inhibitors; Nucleus Accumbens; Piperazines; Pyrrolidines; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate | 2001 |
Intrathecal high-dose morphine induces spinally-mediated behavioral responses through NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Binding, Competitive; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Hindlimb; Hyperalgesia; Injections, Spinal; Male; Mice; Mice, Mutant Strains; Morphine; Naloxone; Narcotic Antagonists; Nerve Tissue Proteins; Pain Measurement; Piperazines; Piperidines; Pyrrolidinones; Reaction Time; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid; Spinal Cord; Subarachnoid Space | 2002 |
Cooperation between independent hippocampal synapses is controlled by glutamate uptake.
Topics: Animals; Aspartic Acid; Biological Transport; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; In Vitro Techniques; Patch-Clamp Techniques; Piperazines; Pyramidal Cells; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Synapses | 2002 |
Hypotension-induced dopamine release in prefrontal cortex is mediated by local glutamatergic projections at the level of nerve terminals.
Topics: Animals; Dopamine; Excitatory Amino Acid Antagonists; Glutamic Acid; Handling, Psychological; Hypotension; Male; Microdialysis; Nitroprusside; Nucleus Accumbens; Piperazines; Prefrontal Cortex; Presynaptic Terminals; Quinoxalines; Rats; Rats, Wistar; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Ventral Tegmental Area | 2002 |
Expression of heat shock protein 70 induced by 4-aminopyridine through glutamate-mediated excitotoxic stress in rat hippocampus in vivo.
Topics: 4-Aminopyridine; Animals; Anticonvulsants; Cell Count; Chromatography, High Pressure Liquid; Dizocilpine Maleate; Drug Interactions; Electroencephalography; Epilepsy; Extracellular Space; Functional Laterality; Gene Expression; Glutamic Acid; Hippocampus; HSP70 Heat-Shock Proteins; Immunohistochemistry; Male; Microdialysis; Nerve Degeneration; Neuroprotective Agents; Piperazines; Potassium Channel Blockers; Quinoxalines; Rats; Rats, Wistar; Somatosensory Cortex; Stress, Physiological; Time Factors | 2003 |
Activation of group III metabotropic glutamate receptors presynaptically reduces both GABAergic and glutamatergic transmission in the rat globus pallidus.
Topics: Animals; Animals, Newborn; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; GABA Antagonists; gamma-Aminobutyric Acid; Globus Pallidus; Glutamic Acid; In Vitro Techniques; Internal Capsule; Iontophoresis; Male; Membrane Potentials; Neural Inhibition; Neurons; Patch-Clamp Techniques; Piperazines; Propionates; Pyridazines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Receptors, Presynaptic; Synaptic Transmission | 2003 |
Functional analysis of glutamate transporters in excitatory synaptic transmission of GLAST1 and GLAST1/EAAC1 deficient mice.
Topics: Amino Acid Transport System X-AG; Animals; Animals, Newborn; Astrocytes; Blotting, Western; Brain; Cells, Cultured; Electric Stimulation; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Excitatory Amino Acid Transporter 1; Excitatory Postsynaptic Potentials; Glutamates; Glutamic Acid; Immunohistochemistry; In Situ Nick-End Labeling; In Vitro Techniques; Mice; Mice, Knockout; Patch-Clamp Techniques; Piperazines; Purkinje Cells; Quinoxalines; RNA; Stem Cells; Synaptic Transmission; Time Factors | 2004 |
The 5-HT receptor antagonist M100,907 prevents extracellular glutamate rising in response to NMDA receptor blockade in the mPFC.
Topics: 2-Amino-5-phosphonovalerate; Analysis of Variance; Animals; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Extracellular Space; Fluorobenzenes; Glutamic Acid; Male; Microdialysis; Nicotine; Piperazines; Piperidines; Potassium Chloride; Prefrontal Cortex; Rats; Receptor, Serotonin, 5-HT2A; Receptors, N-Methyl-D-Aspartate; Serotonin; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Tetrodotoxin | 2004 |
CPP and amlodipine alter the decrease in basal acetylcholine and choline release by audiogenic stimulus in hippocampus of ethanol-withdrawn rats in vivo.
Topics: Acetylcholine; Acoustic Stimulation; Alcohol-Induced Disorders, Nervous System; Amlodipine; Animals; Body Weight; Calcium Channel Blockers; Choline; Disease Models, Animal; Down-Regulation; Drug Interactions; Epilepsy, Reflex; Ethanol; Excitatory Amino Acid Agonists; Glutamic Acid; Hippocampus; Male; Microdialysis; Neural Pathways; Piperazines; Rats; Rats, Wistar; Seizures; Substance Withdrawal Syndrome; Synaptic Transmission | 2004 |
Presenilin attenuates receptor-mediated signaling and synaptic function.
Topics: Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Carbamates; Carbazoles; Cell Adhesion Molecules; Cell Line, Tumor; Cell Membrane; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; DCC Receptor; Dipeptides; Endopeptidases; Excitatory Postsynaptic Potentials; Genes, DCC; Glutamic Acid; Indoles; Lidocaine; Membrane Proteins; Memory; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurites; Neuroblastoma; Neurons; Piperazines; Presenilin-1; Protein Processing, Post-Translational; Pyrroles; Quinoxalines; Rats; Receptors, Cell Surface; Recombinant Fusion Proteins; Second Messenger Systems; Synaptic Transmission; Transfection; Tumor Suppressor Proteins | 2005 |
Local injection of a glutamate uptake inhibitor into the ventral tegmental area produces sensitization to the behavioural effects of d-amphetamine.
Topics: Animals; Dextroamphetamine; Dicarboxylic Acids; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Microinjections; Motor Activity; Piperazines; Pyrrolidines; Rats; Rats, Inbred Strains; Ventral Tegmental Area | 2005 |
The 5-HT(1A) receptor agonist 8-OH-DPAT prevents prefrontocortical glutamate and serotonin release in response to blockade of cortical NMDA receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Chromatography, High Pressure Liquid; Dialysis; Dose-Response Relationship, Drug; Drug Interactions; Electrochemistry; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Piperazines; Prefrontal Cortex; Pyridines; Rats; Receptors, N-Methyl-D-Aspartate; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists | 2006 |
Differential modulation of thalamic neurons by optokinetic nuclei in the pigeon.
Topics: Acetylcholine; Action Potentials; Anesthetics, Local; Animals; Brain Mapping; Columbidae; Electric Stimulation; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Lidocaine; Neural Inhibition; Neurons; Photic Stimulation; Piperazines; Thalamus; Visual Pathways | 2006 |
Blockade of NMDA receptors in the prefrontal cortex increases dopamine and acetylcholine release in the nucleus accumbens and motor activity.
Topics: 3,4-Dihydroxyphenylacetic Acid; Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cholinergic Antagonists; Dopamine; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Flupenthixol; Glutamic Acid; Homovanillic Acid; Injections, Intraventricular; Male; Mecamylamine; Microinjections; Motor Activity; Muscarinic Antagonists; N-Methylaspartate; Nicotinic Antagonists; Nucleus Accumbens; Piperazines; Prefrontal Cortex; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; Scopolamine | 2008 |
HSP70 expression protects against hippocampal neurodegeneration induced by endogenous glutamate in vivo.
Topics: 4-Aminopyridine; Animals; Cell Count; Disease Models, Animal; Dizocilpine Maleate; Electroencephalography; Functional Laterality; Glutamic Acid; Hippocampus; HSP70 Heat-Shock Proteins; Male; Neurodegenerative Diseases; Neuroprotective Agents; Piperazines; Rats; Rats, Wistar; Time Factors | 2008 |
Endogenous serotonin and serotonin2C receptors are involved in the ability of M100907 to suppress cortical glutamate release induced by NMDA receptor blockade.
Topics: Animals; Behavior, Animal; Cerebral Cortex; Chromatography, High Pressure Liquid; Ethylamines; Excitatory Amino Acid Antagonists; Fluorobenzenes; Glutamic Acid; Indoles; Male; Microdialysis; Piperazines; Piperidines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2C; Receptors, N-Methyl-D-Aspartate; Serotonin; Serotonin 5-HT2 Receptor Agonists; Serotonin Antagonists; Time Factors | 2009 |
Evaluating statistical methods used to estimate the number of postsynaptic receptors.
Topics: Algorithms; Binomial Distribution; Computer Simulation; Dendritic Spines; Excitatory Amino Acid Antagonists; Glutamic Acid; Kinetics; Markov Chains; Models, Neurological; Piperazines; Receptors, N-Methyl-D-Aspartate; Stochastic Processes; Synapses; Synaptic Transmission | 2009 |
Sertindole restores attentional performance and suppresses glutamate release induced by the NMDA receptor antagonist CPP.
Topics: Analysis of Variance; Animals; Antipsychotic Agents; Attention; Behavior, Animal; Choice Behavior; Clozapine; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Glutamic Acid; Imidazoles; Indoles; Male; Microdialysis; Neuropsychological Tests; Photic Stimulation; Piperazines; Rats; Rats, Sprague-Dawley; Reaction Time | 2011 |
Effects of aripiprazole, olanzapine, and haloperidol in a model of cognitive deficit of schizophrenia in rats: relationship with glutamate release in the medial prefrontal cortex.
Topics: Analysis of Variance; Animals; Antipsychotic Agents; Aripiprazole; Behavior, Animal; Benzodiazepines; Choice Behavior; Cognition Disorders; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamic Acid; Haloperidol; Impulsive Behavior; Male; Microdialysis; Neuropsychological Tests; Olanzapine; Piperazines; Prefrontal Cortex; Quinolones; Rats; Reaction Time; Schizophrenia; Serotonin; Time Factors | 2011 |
Attention deficit induced by blockade of N-methyl D-aspartate receptors in the prefrontal cortex is associated with enhanced glutamate release and cAMP response element binding protein phosphorylation: role of metabotropic glutamate receptors 2/3.
Topics: Amino Acids; Animals; Attention Deficit Disorder with Hyperactivity; Behavior, Animal; Blotting, Western; Bridged Bicyclo Compounds, Heterocyclic; Cyclic AMP Response Element-Binding Protein; Excitatory Amino Acid Antagonists; Glutamic Acid; Immunohistochemistry; Male; Microdialysis; Microinjections; Phosphorylation; Piperazines; Prefrontal Cortex; Rats; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate | 2011 |
Serotonin activates catecholamine neurons in the solitary tract nucleus by increasing spontaneous glutamate inputs.
Topics: Action Potentials; Animals; Catecholamines; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; Male; Mice; Neurons; Patch-Clamp Techniques; Piperazines; Pyrazines; Quinoxalines; Receptors, Presynaptic; Receptors, Serotonin, 5-HT3; Serotonin; Serotonin Receptor Agonists; Solitary Nucleus; Tyrosine 3-Monooxygenase | 2012 |
NMDA spike/plateau potentials in dendrites of thalamocortical neurons.
Topics: Action Potentials; Animals; Cerebral Cortex; Dendrites; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; Male; Mice; Mice, Inbred C57BL; Neural Pathways; Neurons; Piperazines; Receptors, N-Methyl-D-Aspartate; Thalamus | 2014 |
Interneurons spark seizure-like activity in the entorhinal cortex.
Topics: 4-Aminopyridine; Action Potentials; Animals; Disease Models, Animal; Entorhinal Cortex; Excitatory Amino Acid Antagonists; Glutamic Acid; Interneurons; Male; Piperazines; Quinoxalines; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Seizures; Tissue Culture Techniques | 2016 |