3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid has been researched along with dizocilpine maleate in 170 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 22 (12.94) | 18.7374 |
| 1990's | 117 (68.82) | 18.2507 |
| 2000's | 28 (16.47) | 29.6817 |
| 2010's | 3 (1.76) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Kelder, D; Rényi, L; Ross, SB | 1 |
| Acuff, CG; Farley, JM; Ho, IK; Hoskins, B; Oden, G; Rockhold, RW; Surrett, RS; Zhang, T | 1 |
| Morimoto, K; Sato, M | 1 |
| Hisanaga, K; Sagar, SM; Sharp, FR | 1 |
| Dawes, E; Hankins, M; Ikeda, H | 1 |
| Ishii, T; Masu, M; Moriyoshi, K; Nakanishi, S; Sugihara, H | 1 |
| Molinoff, PB; Powel, RJ; Pullan, LM; Romano, C; Salama, AI; Williams, K | 1 |
| Dubner, R; Hylden, JL; Ren, K; Ruda, MA; Williams, GM | 1 |
| Argiolas, A; Melis, MR; Stancampiano, R | 1 |
| Dutton, GR; Rogers, KL | 1 |
| Beaton, JA; Monaghan, DT; Stemsrud, K | 1 |
| Darlington, CL; Smith, PF | 3 |
| Pezzola, A; Sagratella, S; Scotti De Carolis, A; Zeng, YC | 1 |
| Aamodt, SM; Kozlowski, MR; Nordeen, EJ; Nordeen, KW | 1 |
| Akiyama, K; Kanzaki, A; Otsuki, S; Tsuchida, H; Ujike, H | 1 |
| Clissold, DB; Ferkany, JW; Pontecorvo, MJ; White, MF | 1 |
| Kuramoto, K; Nishimura, S; Sorimachi, M | 1 |
| Monaghan, DT | 1 |
| Bowen, WD; Reid, AA; Rothman, RB; Setterlund, C | 1 |
| Bakker, MH; Foster, AC | 1 |
| Andrew, M; Farley, JM; Ho, IK; Oden, G; Rockhold, RW | 1 |
| Avoli, M; Hwa, GG | 2 |
| Katki, AG; Rodbard, D; Schwarz, S; Zhou, GZ | 1 |
| Thompson, SWN; Woolf, CJ | 1 |
| Acciarri, N; Antonelli, T; Beani, L; Bianchi, C; Calo, G; Fabrizi, A; Gaist, G; Morari, M | 1 |
| Colwell, CS; Foster, RG; Menaker, M | 1 |
| Inoue, K; Katayama, K; Morimoto, K; Sato, K | 1 |
| Ebert, B; Ferkany, JW; Holm, T; Johansen, TN; Jones, BE; Krogsgaard-Larsen, P; Madsen, U | 1 |
| Hughes, J; Hunter, JC; Singh, L; Vass, CA; Woodruff, GN | 1 |
| Gotoh, Y; Ishida, M; Shinozaki, H | 1 |
| Akaike, N; Murase, K; Nakagawa, T; Shirasaki, T; Tateishi, N | 1 |
| Corbett, R; Cornfeldt, ML; Dunn, RW; Fielding, S; Laws-Ricker, L; Martin, LL; Payack, JF; Rush, DK; Wilmot, CA | 1 |
| Foucaud, B; Gombos, G | 1 |
| Chiamulera, C; Costa, S; Reggiani, A | 1 |
| Balster, RL; Tokarz, ME; Willetts, J | 1 |
| Keith, R; Patel, J; Salama, A; Thompson, C; Zinkand, WC | 1 |
| Katayama, K; Morimoto, K; Ohnishi, M; Okamoto, M; Otsuki, S; Sato, K | 1 |
| Parada-Turska, J; Turski, WA | 1 |
| Costa, E; Eimerl, S; Schramm, M | 1 |
| Kim, HS; Lehmann, J; Martin, LL; Rao, TS; Wood, PL | 1 |
| Crawford, RD; Johnson, DD; Pedder, SC; Tuchek, JM; Wilcox, RI | 1 |
| Besson, MJ; Maurin, Y; Mitrovic, N | 1 |
| Meldrum, BS; Swan, JH | 1 |
| Darlington, CL; Hubbard, JI; Smith, PF | 1 |
| Dziki, M; Ikonomidou, C; Parada-Turska, J; Turski, WA; Urbanska, E | 1 |
| Aebischer, B; Lowe, DA; Neijt, HC | 1 |
| Bertram, EH; Lothman, EW | 1 |
| Abraham, WC; Mason, SE; Ward, L | 1 |
| Klockgether, T; Turski, L | 1 |
| Abraham, WC; Kirk, RC; McNaughton, N; Tan, S | 1 |
| Balster, RL; Willetts, J | 2 |
| Cler, J; Emmett, MR; Iyengar, S; Mick, S; Rao, TS; Wood, PL | 1 |
| Kurumaji, A; McCulloch, J; Nehls, DG; Park, CK | 2 |
| Arnolde, SM; Nevins, ME | 1 |
| Costa, E; Danysz, W; Fadda, E; Wroblewski, JT | 2 |
| Sawyer, BD; Shannon, HE | 1 |
| Benedict, MS; Fagg, GE; Thedinga, KH | 1 |
| Jackson, A; Sanger, DJ | 1 |
| Goto, Y; Ishida, M; Shinozaki, H | 1 |
| Johnston, MV; McDonald, JW; Roeser, NF; Silverstein, FS | 1 |
| Abraham, WC; Mason, SE | 1 |
| Lehmann, J; Tsai, C; Wood, PL | 1 |
| Childs, AM; Evans, RH; Watkins, JC | 1 |
| Foster, AC; Gill, R; Woodruff, GN | 1 |
| Ho, PM; Tang, AH | 1 |
| Akaike, A; Kimura, J; Shimohama, S; Tamura, Y; Yokota, T | 1 |
| Cheng, C; Chugh, A; Johnson, RL; Mishra, RK; Savelli, JE | 1 |
| Gancher, S; Mayer, A | 1 |
| Colwell, CS; Kaufman, CM; Menaker, M | 1 |
| Larson, AA; Sun, X | 4 |
| Faingold, CL; Riaz, A | 1 |
| Ammendola, D; De Sarro, A; De Sarro, G; Nava, F | 1 |
| Katsuta, K; Kuno, A; Nakanishi, H; Ogita, K; Ohkubo, M; Shirakawa, K; Takasugi, H; Ueda, Y; Yoneda, Y; Yoshida, K | 1 |
| Carta, A; Fenu, S; Morelli, M | 1 |
| Gobert, A; Lejeune, F; Millan, MJ; Rivet, JM | 1 |
| Bedingfield, JB; Calder, LD; Karler, R; Thai, LH | 1 |
| Kreeger, JS; Larson, AA | 1 |
| Starr, BS; Starr, MS | 2 |
| Cole, BJ; Jones, GH; Klewer, M; Stephens, DN | 1 |
| Daunais, JB; McGinty, JF; Wang, JQ | 1 |
| Han, D; Ogita, K; Suzuki, T; Yoneda, Y; Zuo, P | 1 |
| Jayaraman, A; Kiba, H | 1 |
| Hasegawa, T; Kameyama, T; Kinoshita, H; Nabeshima, T; Yamamoto, I | 1 |
| Goettl, VM; Larson, AA | 1 |
| Baudry, M; Marvizón, JC | 1 |
| Penney, JB; Sakurai, SY; Young, AB | 1 |
| Bowery, NG; Gaviraghi, G; Marien, MR; Ratti, E; Tacconi, S | 1 |
| Bianchi, L; Giovannini, MG; Michelassi, A; Mutolo, D; Pepeu, G | 1 |
| Boldry, RC; Kelland, MD; Soltis, RP; Walters, JR | 1 |
| Pellicano, MP; Sadile, AG; Siciliano, F | 1 |
| Rivier, C; Torres, G | 1 |
| Boersma Anderson, CA; Faingold, CL; Naritoku, DK; Randall, ME | 1 |
| French, ED; Mura, A; Wang, T | 1 |
| Harro, J; Kôks, S; Lang, A; Oöpik, T; Sihver, S; Soosaar, A; Vasar, E; Volke, V | 1 |
| Carter, C; Fage, D; Voltz, C | 1 |
| Cordery, PM; Smith, AL; Thompson, ID | 1 |
| Benardo, LS | 1 |
| Mishra, RK; Nair, VD; Niznik, HB | 1 |
| Follesa, P; Ticku, MK | 1 |
| Ikonomidou, C; Kirby, C; Labruyere, J; Olney, JW; Qin, Y | 1 |
| Doyle, KM; Shaw, GG | 1 |
| Emmi, A; Rajabi, H; Stewart, J | 1 |
| Darlington, CL; Jerram, AH; Smith, PF | 1 |
| Morales-Villagrán, A; Tapia, R; Ureña-Guerrero, ME | 1 |
| Cabib, S; Caccia, S; Castellano, C; Felici, A; Mele, A; Oliverio, A | 1 |
| Carlezon, WA; Wise, RA | 1 |
| Lemaire, S; Shukla, VK | 1 |
| Capek, R; Esplin, B | 1 |
| Liu, Y; Souverbie, F; Sundström, E; von Euler, G | 1 |
| Cory-Slechta, DA | 1 |
| Kawabe, A; Maruoka, Y; Nakamura, M; Ohno, Y; Ohtani, K; Sakamoto, H; Tamamura, C; Tanaka, H; Yasuda, H | 1 |
| Baird, DH; Console-Bram, LM; Fitzpatrick-McElligott, SG; McElligott, JG | 1 |
| Ikarashi, Y; Ishimaru, H; Maruyama, Y; Shiobara, T; Takahashi, A; Yuzurihara, M | 1 |
| Bartfai, T; Caltavuturo, C; Consolo, S; Uboldi, MC | 1 |
| Bergstrom, DA; Huang, KX; Ruskin, DN; Walters, JR | 1 |
| Ikarashi, Y; Ishimaru, H; Maruyama, Y; Shiobara, T; Takahashi, A | 1 |
| Simpson, VJ; Velardo, MJ; Zahniser, NR | 1 |
| Doyle, KM; Eddleston, A; Feerick, S; Higgins, GA; Kirkby, DL | 1 |
| Fahey, JM; Greenblatt, DJ; Pratt, JS; Pritchard, GA; Shader, RI | 1 |
| Bittigau, P; Hübner, C; Ikonomidou, C; Ishimaru, MJ; Olney, JW; Pohl, D; Stadthaus, D; Turski, L | 1 |
| Cobanoğlu, S; Görgülü, A; Kiriş, T; Küçük, M; Türkoğlu, U; Unal, F | 1 |
| Gidday, JM; Holtzman, DM; Maceren, RG; Park, TS; Pelligrino, DA; Shah, AR; Wang, Q | 1 |
| Vanover, KE | 1 |
| Alavez, S; Hurtado, S; Moran, J; Rivera-Gaxiola, M; Valencia, A | 1 |
| Pollack, AE; Strauss, JB | 1 |
| Iravani, MM; Kruk, ZL; Muscat, R | 1 |
| Cobanoğlu, S; Ekuklu, G; Görgülü, A; Kiriş, T; Türkoğlu, U; Unal, F | 1 |
| Bandtlow, CE; Gähwiler, BH; Lüthi, A; McKinney, RA; Thompson, SM | 1 |
| Dewar, KM; Elie, R; Vasiliadis, HM | 1 |
| Bervoets, K; Brocco, M; Gobert, A; Millan, MJ; Rivet, JM; Veiga, S | 1 |
| Audinot, V; Bervoets, K; Brocco, M; Honoré, P; Millan, MJ; Veiga, S | 1 |
| Elliot, J; Grimwood, S; Huscroft, I; Hutson, PH; Kennedy, J; Mohnen, K; Murray, F; Russell, MG | 1 |
| Gemignani, A; Paudice, P; Pittaluga, A; Raiteri, M | 1 |
| Battisti, JJ; Uretsky, NJ; Wallace, LJ | 1 |
| Ikonomidou, C; Stefovska, V; Turski, L | 1 |
| Eshak, M; Iannotti, F; Pringle, AK; Self, J | 1 |
| Battisti, JJ; Shreffler, CB; Uretsky, NJ; Wallace, LJ | 1 |
| Ahlenius, S; Eriksson, C; Schultzberg, M; Winblad, B; Zou, LP | 1 |
| Blaszczak, P; Dekundy, A; Kaminski, R; Turski, WA | 1 |
| Castrén, E; Haapasalo, A; Lakso, M; Lee, D; Lindén, A; Sei, Y; Storvik, M; Witkin, JM; Wong, G | 1 |
| Haisley, EC; Pollack, AE | 1 |
| Aoki, K; Narita, M; Nomura, M; Suzuki, T; Yoshizawa, K | 1 |
| Gähwiler, BH; Lüthi, A; Mateos, JM; McKinney, RA; Schwyzer, L | 1 |
| Bedi, KS; Bellinger, FP; Wilce, PA; Wilson, P | 1 |
| Moriyama, T; Okuda, K; Sakurada, C; Sakurada, S; Sakurada, T; Sugiyama, A; Tan-No, K; Watanabe, C | 1 |
| Arnth-Jensen, N; Jabaudon, D; Scanziani, M | 1 |
| Farkas, S; Kocsis, P; Szombathelyi, Z; Tarnawa, I | 1 |
| Ayala, GX; Tapia, R | 2 |
| Bertram, EH; Kapur, J; Williamson, J; Yen, W | 1 |
| Bennett, S; Gronier, B | 1 |
| Dekundy, A; Kaminski, RM; Turski, WA; Zielinska, E | 1 |
| Ito, S; Kita, T; Matsubayashi, K; Mori, T; Narita, M; Sawaguchi, T; Suzuki, T | 1 |
| Abraham, WC; Guévremont, D; Kennard, JT; Mason-Parker, SE; Williams, JM | 1 |
| Leung, JC; Marphis, T; Ragland, N; Silverstein, DM | 1 |
| Brown, TE; Lee, BR; Sorg, BA | 1 |
| Akita, H; Honda, Y; Noda, K; Ogata, M; Saji, M | 1 |
| Gacsályi, I; Kapus, G; Kertész, S; Lévay, G | 1 |
| Adachi, M; Autry, AE; Cheng, PF; Kavalali, ET; Los, MF; Monteggia, LM; Na, ES; Nosyreva, E | 1 |
170 other study(ies) available for 3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid and dizocilpine maleate
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
N-methyl-D-aspartate receptor antagonists counteract the long lasting 5-HT1A receptor-induced attenuation of postsynaptic responses in the rat in vivo.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Corticosterone; Dizocilpine Maleate; Ion Channels; Male; Phencyclidine; Piperazines; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; Shivering; Synapses | 1992 |
Inhibition of cocaine intoxication by excitatory amino acid receptor antagonists.
Topics: Animals; Anticonvulsants; Cocaine; Death; Dextrorphan; Dizocilpine Maleate; Glutamates; Kynurenic Acid; Male; Mice; Mice, Inbred ICR; Neurotoxins; Piperazines; Receptors, Neurotransmitter; Seizures | 1992 |
NMDA receptor complex and kindling mechanisms.
Topics: Amygdala; Animals; Dizocilpine Maleate; Dose-Response Relationship, Drug; Electric Stimulation; Hippocampus; Kindling, Neurologic; Kynurenic Acid; Male; Neural Pathways; Pipecolic Acids; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses; Synaptic Transmission | 1992 |
N-methyl-D-aspartate antagonists block fos-like protein expression induced via multiple signaling pathways in cultured cortical neurons.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Blotting, Northern; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Fetus; Glutamates; Glutamic Acid; Immunohistochemistry; N-Methylaspartate; Neurons; Piperazines; Proto-Oncogene Proteins c-fos; Signal Transduction | 1992 |
Spontaneous firing level distinguishes the effects of NMDA and non-NMDA receptor antagonists on the ganglion cells in the cat retina.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Cats; Dizocilpine Maleate; Evoked Potentials, Visual; Ganglia; Iontophoresis; Kynurenic Acid; Piperazines; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Retina | 1992 |
Structures and properties of seven isoforms of the NMDA receptor generated by alternative splicing.
Topics: 2-Amino-5-phosphonovalerate; Amino Acid Sequence; Animals; Base Sequence; Chromosome Deletion; Cloning, Molecular; Dizocilpine Maleate; DNA; Gene Library; Kynurenic Acid; Molecular Sequence Data; N-Methylaspartate; Oocytes; Piperazines; Prosencephalon; Rats; Receptors, N-Methyl-D-Aspartate; Restriction Mapping; RNA Splicing; RNA, Messenger; Xenopus | 1992 |
An antagonist/partial agonist at the polyamine recognition site of the N-methyl-D-aspartate receptor that alters the properties of the glutamate recognition site.
Topics: Animals; Binding Sites; Dizocilpine Maleate; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; Glycine; In Vitro Techniques; Piperazines; Polyamines; Rats; Receptors, N-Methyl-D-Aspartate; Spermine | 1992 |
The intrathecal administration of excitatory amino acid receptor antagonists selectively attenuated carrageenan-induced behavioral hyperalgesia in rats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Analgesics; Analysis of Variance; Animals; Behavior, Animal; Carrageenan; Dizocilpine Maleate; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Hyperalgesia; Inflammation; Injections, Spinal; Ketamine; Kynurenic Acid; Male; Piperazines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Valine | 1992 |
Effect of excitatory amino acid receptor antagonists on apomorphine-, oxytocin- and ACTH-induced penile erection and yawning in male rats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adrenocorticotropic Hormone; Aminobutyrates; Animals; Apomorphine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Injections, Intraventricular; Injections, Subcutaneous; Male; Oxytocin; Penile Erection; Piperazines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Amino Acid; Yawning | 1992 |
Evoked endogenous taurine release from cultured cerebellar neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Cerebellum; Dizocilpine Maleate; Ibotenic Acid; Kainic Acid; N-Methylaspartate; Neurons; Piperazines; Quinoxalines; Quisqualic Acid; Rats; Receptors, N-Methyl-D-Aspartate; Taurine | 1992 |
Identification of a novel N-methyl-D-aspartate receptor population in the rat medial thalamus.
Topics: Animals; Autoradiography; Cerebellum; Dizocilpine Maleate; Glutamates; Phenazocine; Piperazines; Prosencephalon; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Thalamus | 1992 |
Comparison of the effects of NMDA antagonists on medial vestibular nucleus neurons in brainstem slices from labyrinthine-intact and chronically labyrinthectomized guinea pigs.
Topics: Animals; Brain Stem; Dizocilpine Maleate; Ear, Inner; Guinea Pigs; In Vitro Techniques; Piperazines; Receptors, N-Methyl-D-Aspartate | 1992 |
Inhibitory influence of morphinans on ictal and interictal EEG changes induced by cortical application of penicillin in rabbits: a comparative study with NMDA antagonists and pentobarbitone.
Topics: Animals; Behavior, Animal; Cerebral Cortex; Dizocilpine Maleate; Electroencephalography; Injections; Male; Morphinans; N-Methylaspartate; Penicillins; Pentobarbital; Piperazines; Rabbits; Receptors, N-Methyl-D-Aspartate; Seizures | 1992 |
Distribution and developmental change in [3H]MK-801 binding within zebra finch song nuclei.
Topics: Aging; Animals; Auditory Pathways; Autoradiography; Binding, Competitive; Birds; Dizocilpine Maleate; Image Processing, Computer-Assisted; Kynurenic Acid; Male; Neostriatum; Piperazines; Prosencephalon; Receptors, N-Methyl-D-Aspartate; Vocalization, Animal | 1992 |
Competitive and non-competitive N-methyl-D-aspartate antagonists fail to prevent the induction of methamphetamine-induced sensitization.
Topics: Animals; Binding, Competitive; Dizocilpine Maleate; Drug Administration Schedule; Male; Methamphetamine; Motor Activity; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Schizophrenia | 1992 |
N-methyl-D-aspartate antagonists and working memory performance: comparison with the effects of scopolamine, propranolol, diazepam, and phenylisopropyladenosine.
Topics: Amino Acids; Animals; Appetitive Behavior; Brain; Diazepam; Discrimination Learning; Dizocilpine Maleate; Dose-Response Relationship, Drug; Male; Mental Recall; Phencyclidine; Phenylisopropyladenosine; Piperazines; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, N-Methyl-D-Aspartate; Receptors, Purinergic; Retention, Psychology; Scopolamine | 1991 |
Receptor types mediating the rise in the cytosolic free calcium concentration by L-aspartate and L-glutamate in immature cerebellar neurons with N-methyl-D-aspartate receptors.
Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Aspartic Acid; Calcium; Cerebellum; Cytosol; Dizocilpine Maleate; Glutamates; Glutamic Acid; Kinetics; Magnesium; Neurons; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate | 1991 |
Differential stimulation of [3H]MK-801 binding to subpopulations of NMDA receptors.
Topics: Animals; Autoradiography; Brain Chemistry; Cerebral Cortex; Corpus Striatum; Dizocilpine Maleate; Glutamates; Glutamic Acid; In Vitro Techniques; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Thalamus; Valine | 1991 |
The competitive NMDA receptor antagonist, CPP, allosterically modulates NMDA receptor associated PCP binding sites in the absence of steric hinderance.
Topics: Animals; Dizocilpine Maleate; Glutamates; Glutamic Acid; Guinea Pigs; In Vitro Techniques; Kinetics; Membranes; Molecular Conformation; Phencyclidine; Piperazines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Receptors, Phencyclidine | 1990 |
An investigation of the mechanisms of delayed neurodegeneration caused by direct injection of quinolinate into the rat striatum in vivo.
Topics: Adrenergic alpha-Antagonists; Animals; Anticonvulsants; Convulsants; Corpus Striatum; Dialysis; Diazepam; Dizocilpine Maleate; Glutamate Decarboxylase; Haloperidol; Ibotenic Acid; Injections; Male; Nerve Degeneration; Pipecolic Acids; Piperazines; Piperidines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Stereotaxic Techniques | 1991 |
Glutamate receptor antagonists block cocaine-induced convulsions and death.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Anticonvulsants; Cocaine; Death; Dextrorphan; Dizocilpine Maleate; Dose-Response Relationship, Drug; Glutamates; Kynurenic Acid; Male; Mice; Mice, Inbred ICR; Piperazines; Quinoxalines; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures; Time Factors | 1991 |
The involvement of excitatory amino acids in neocortical epileptogenesis: NMDA and non-NMDA receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Bicuculline; Cerebral Cortex; Dizocilpine Maleate; Electric Stimulation; Epilepsy; In Vitro Techniques; Male; Membrane Potentials; N-Methylaspartate; Neurons; Piperazines; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate | 1991 |
L-homocysteate stimulates [3H]MK-801 binding to the phencyclidine recognition site and is thus an agonist for the N-methyl-D-aspartate-operated cation channel.
Topics: 2-Amino-5-phosphonovalerate; Animals; Dizocilpine Maleate; Homocysteine; In Vitro Techniques; Ion Channels; Kinetics; Male; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Receptors, Phencyclidine; Stereoisomerism; Stimulation, Chemical | 1990 |
The induction and maintenance of central sensitization is dependent on N-methyl-D-aspartic acid receptor activation; implications for the treatment of post-injury pain hypersensitivity states.
Topics: Action Potentials; Animals; Dizocilpine Maleate; Motor Neurons; Mustard Plant; Pain; Physical Stimulation; Piperazines; Plant Extracts; Plant Oils; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Reflex; Sural Nerve; Wounds and Injuries | 1991 |
Inhibitory effect of NMDA receptor activation on quisqualate-stimulated phosphatidylinositol turnover in the human cerebral cortex.
Topics: Amino Acids; Cerebral Cortex; Dizocilpine Maleate; Female; Humans; Hydrolysis; Ibotenic Acid; In Vitro Techniques; Male; Middle Aged; Phosphatidylinositols; Piperazines; Quisqualic Acid; Receptors, N-Methyl-D-Aspartate | 1991 |
NMDA receptor antagonists block the effects of light on circadian behavior in the mouse.
Topics: Animals; Circadian Rhythm; Dizocilpine Maleate; Dose-Response Relationship, Drug; Light; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Motor Activity; Piperazines; Receptors, N-Methyl-D-Aspartate | 1991 |
Effects of competitive and noncompetitive NMDA receptor antagonists on kindling and LTP.
Topics: Animals; Binding, Competitive; Dizocilpine Maleate; Electric Stimulation; Evoked Potentials; Kindling, Neurologic; Male; Neuronal Plasticity; Pipecolic Acids; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate | 1991 |
NMDA receptor agonists derived from ibotenic acid. Preparation, neuroexcitation and neurotoxicity.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Choline O-Acetyltransferase; Corpus Callosum; Dizocilpine Maleate; Ibotenic Acid; In Vitro Techniques; Nervous System; Nervous System Diseases; Piperazines; Rats; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Stimulation, Chemical | 1990 |
The anticonvulsant action of CI-977, a selective kappa-opioid receptor agonist: a possible involvement of the glycine/NMDA receptor complex.
Topics: Animals; Anticonvulsants; Benzofurans; Dizocilpine Maleate; In Vitro Techniques; Mice; Mice, Inbred Strains; Naltrexone; Piperazines; Pyrrolidines; Radioligand Assay; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid; Receptors, Opioid, kappa; Seizures; Stereoisomerism | 1990 |
Selective N-methyl-D-aspartate (NMDA) antagonists increase gastric motility in the rat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Autonomic Nervous System; Dibenzocycloheptenes; Dizocilpine Maleate; Dose-Response Relationship, Drug; Male; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Stomach | 1990 |
Effects of antagonists on N-methyl-D-aspartate response in acutely isolated nucleus tractus solitarii neurons of the rat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Dibenzocycloheptenes; Dizocilpine Maleate; In Vitro Techniques; Medulla Oblongata; N-Methylaspartate; Piperazines; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1990 |
Preclinical anxiolytic profiles of 7189 and 8319, novel non-competitive NMDA antagonists.
Topics: Aniline Compounds; Animals; Anti-Anxiety Agents; Anticonvulsants; Behavior, Animal; Binding, Competitive; Diazepam; Dizocilpine Maleate; Dose-Response Relationship, Drug; Learning; Male; Mice; N-Methylaspartate; Piperazines; Rats; Rats, Inbred Strains; Seizures; Thiophenes; Tritium; Yohimbine | 1990 |
Identification and characterization of a high-affinity glutamate-controlled TCP binding site in rat brain postsynaptic densities.
Topics: Animals; Brain; Cell Membrane; Dizocilpine Maleate; Glutamates; Glutamic Acid; In Vitro Techniques; Kinetics; Phencyclidine; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Receptors, Phencyclidine; Subcellular Fractions; Synapses; Synaptosomes | 1990 |
Effect of NMDA- and strychnine-insensitive glycine site antagonists on NMDA-mediated convulsions and learning.
Topics: 2-Amino-5-phosphonovalerate; Animals; Dizocilpine Maleate; Injections, Intraventricular; Kynurenic Acid; Learning; Male; Mice; N-Methylaspartate; Piperazines; Receptors, Glycine; Receptors, Neurotransmitter; Seizures; Strychnine | 1990 |
Pentobarbital-like effects of N-methyl-D-aspartate antagonists in mice.
Topics: Animals; Discrimination, Psychological; Dizocilpine Maleate; Dose-Response Relationship, Drug; Male; Mice; N-Methylaspartate; Pentobarbital; Piperazines | 1991 |
Role of glycine in the N-methyl-D-aspartate-mediated neuronal cytotoxicity.
Topics: Animals; Aspartic Acid; Cell Survival; Cells, Cultured; Dibenzocycloheptenes; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Synergism; Glycine; Kynurenic Acid; N-Methylaspartate; Neurons; Piperazines; Pyrrolidinones; Serine | 1990 |
The role of NMDA receptors in epilepsy: I. Effects of NMDA receptor antagonists (CPP and MK-801) on amygdala kindling in rats.
Topics: Amygdala; Animals; Anticonvulsants; Dizocilpine Maleate; Dose-Response Relationship, Drug; Electroencephalography; Evoked Potentials; Kindling, Neurologic; Male; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate | 1990 |
Excitatory amino acid antagonists and memory: effect of drugs acting at N-methyl-D-aspartate receptors in learning and memory tasks.
Topics: Animals; Avoidance Learning; Dizocilpine Maleate; Male; Memory; Mice; Motor Activity; N-Methylaspartate; Pipecolic Acids; Piperazines; Receptors, N-Methyl-D-Aspartate; Reference Values | 1990 |
Serum and depolarizing agents cause acute neurotoxicity in cultured cerebellar granule cells: role of the glutamate receptor responsive to N-methyl-D-aspartate.
Topics: Animals; Anticonvulsants; Aspartic Acid; Blood; Cell Survival; Cells, Cultured; Cerebellum; Culture Media; Cytoplasmic Granules; Dibenzocycloheptenes; Dizocilpine Maleate; Glutamates; N-Methylaspartate; Neuromuscular Depolarizing Agents; Oxadiazoles; Piperazines; Potassium Chloride; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter; Veratridine | 1990 |
Selective activation of dopaminergic pathways in the mesocortex by compounds that act at the phencyclidine (PCP) binding site: tentative evidence for PCP recognition sites not coupled to N-methyl-D-aspartate (NMDA) receptors.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Carbazoles; Cerebral Cortex; Dibenzocycloheptenes; Dizocilpine Maleate; Dopamine; Dose-Response Relationship, Drug; Guanidines; Ligands; Male; Neural Pathways; Pipecolic Acids; Piperazines; Piperidines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Receptors, Phencyclidine; Stereoisomerism | 1990 |
Attenuation of febrile seizures in epileptic chicks by N-methyl-D-aspartate receptor antagonists.
Topics: 2-Amino-5-phosphonovalerate; 2-Aminoadipic Acid; Amino Acids; Animals; Chickens; Diaminopimelic Acid; Dibenzocycloheptenes; Dizocilpine Maleate; Fever; Phenotype; Piperazines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures; Synaptic Membranes | 1990 |
Anticonvulsant effects of antagonists of the N-methyl-D-aspartate receptor complex in a genetic model of epilepsy: the quaking mouse.
Topics: Animals; Anticonvulsants; Dibenzocycloheptenes; Dizocilpine Maleate; Epilepsy; Injections, Intravenous; Male; Mice; Mice, Quaking; Phencyclidine; Physical Stimulation; Piperazines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1990 |
Protection by NMDA antagonists against selective cell loss following transient ischaemia.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Brain; Brain Ischemia; Dibenzocycloheptenes; Dizocilpine Maleate; Male; N-Methylaspartate; Neurons; Pipecolic Acids; Piperazines; Piperidines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1990 |
Evidence that NMDA receptors contribute to synaptic function in the guinea pig medial vestibular nucleus.
Topics: Action Potentials; Animals; Dibenzocycloheptenes; Dizocilpine Maleate; Guinea Pigs; Piperazines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Vestibular Nuclei | 1990 |
Excitatory amino acid antagonists protect mice against seizures induced by bicuculline.
Topics: Animals; Bicuculline; Dibenzocycloheptenes; Dizocilpine Maleate; Dose-Response Relationship, Drug; Male; Mice; Muscimol; Pipecolic Acids; Piperazines; Piperidines; Receptors, Amino Acid; Receptors, Cell Surface; Seizures | 1990 |
D-CPP-ene (SDZ EAA 494), a potent and competitive N-methyl-D-aspartate (NMDA) antagonist: effect on spontaneous activity and NMDA-induced depolarizations in the rat neocortical slice preparation, compared with other CPP derivatives and MK-801.
Topics: Animals; Cerebral Cortex; Dibenzocycloheptenes; Dizocilpine Maleate; Evoked Potentials; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1990 |
NMDA receptor antagonists and limbic status epilepticus: a comparison with standard anticonvulsants.
Topics: Animals; Anticonvulsants; Dibenzocycloheptenes; Dizocilpine Maleate; Electric Stimulation; Hippocampus; Male; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Status Epilepticus | 1990 |
Effects of the NMDA antagonists CPP and MK-801 on radial arm maze performance in rats.
Topics: Animals; Aspartic Acid; Behavior, Animal; Dibenzocycloheptenes; Dizocilpine Maleate; Male; Memory; N-Methylaspartate; Piperazines; Rats; Rats, Inbred Strains; Single-Blind Method | 1990 |
NMDA antagonists potentiate antiparkinsonian actions of L-dopa in monoamine-depleted rats.
Topics: Animals; Dizocilpine Maleate; Drug Synergism; Electromyography; Levodopa; Male; Methyltyrosines; Motor Activity; Muscle Rigidity; N-Methylaspartate; Parkinson Disease; Piperazines; Rats; Rats, Inbred Strains; Reserpine | 1990 |
Effects of the NMDA antagonists CPP and MK-801 on delayed conditional discrimination.
Topics: Animals; Anticonvulsants; Aspartic Acid; Dibenzocycloheptenes; Discrimination, Psychological; Dizocilpine Maleate; Dose-Response Relationship, Drug; Male; N-Methylaspartate; Piperazines; Rats; Rats, Inbred Strains; Stereotyped Behavior | 1989 |
NMDA receptor antagonists CPP and MK-801 partially suppress the epileptiform discharges induced by the convulsant drug bicuculline in the rat neocortex.
Topics: Animals; Bicuculline; Cerebral Cortex; Dibenzocycloheptenes; Dizocilpine Maleate; Epilepsy; Male; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1989 |
Pentobarbital-like discriminative stimulus effects of N-methyl-D-aspartate antagonists.
Topics: Animals; Aspartic Acid; Dibenzocycloheptenes; Discrimination Learning; Dizocilpine Maleate; Dose-Response Relationship, Drug; Flumazenil; Generalization, Psychological; Male; N-Methylaspartate; Pentobarbital; Phencyclidine; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1989 |
In vivo modulation of the N-methyl-D-aspartate receptor complex by D-serine: potentiation of ongoing neuronal activity as evidenced by increased cerebellar cyclic GMP.
Topics: Animals; Aspartic Acid; Cerebellum; Cyclic GMP; Cycloserine; Dibenzocycloheptenes; Dizocilpine Maleate; Male; Mice; N-Methylaspartate; Neurons; Piperazines; Pyrrolidinones; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Serine | 1989 |
Effects of NMDA antagonists, MK-801 and CPP, upon local cerebral glucose use.
Topics: Animals; Brain; Deoxy Sugars; Deoxyglucose; Dibenzocycloheptenes; Dizocilpine Maleate; Male; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1989 |
Effects of competitive and noncompetitive N-methyl-D-aspartate (NMDA) antagonists in rats trained to discriminate NMDA from saline.
Topics: Amino Acids; Animals; Aspartic Acid; Dibenzocycloheptenes; Discrimination Learning; Dizocilpine Maleate; Dose-Response Relationship, Drug; Male; N-Methylaspartate; Phenazocine; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1989 |
A comparison of the anticonvulsant effects of competitive and non-competitive antagonists of the N-methyl-D-aspartate receptor.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Dibenzocycloheptenes; Dizocilpine Maleate; Dose-Response Relationship, Drug; Male; Mice; Pentylenetetrazole; Phencyclidine; Piperazines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures | 1989 |
Kynurenate and 2-amino-5-phosphonovalerate interact with multiple binding sites of the N-methyl-D-aspartate-sensitive glutamate receptor domain.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Binding Sites; Binding, Competitive; Brain; Dibenzocycloheptenes; Dizocilpine Maleate; Kynurenic Acid; Piperazines; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Strychnine; Subcellular Fractions; Valine | 1989 |
Glutamate receptors of the N-methyl-D-aspartate subtype in the myenteric plexus of the guinea pig ileum.
Topics: Animals; Aspartic Acid; Dibenzocycloheptenes; Dizocilpine Maleate; Glutamates; Glutamic Acid; Guinea Pigs; Ileum; Magnesium; Male; Muscle Contraction; Myenteric Plexus; N-Methylaspartate; Piperazines; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1989 |
The N-methyl-D-aspartate (NMDA) receptor complex: a stoichiometric analysis of radioligand binding domains.
Topics: Animals; Binding Sites; Dibenzocycloheptenes; Dizocilpine Maleate; Glutamates; Glutamic Acid; Glycine; Kinetics; Piperazines; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synaptic Membranes; Telencephalon; Tritium | 1989 |
Different modes of action of 3-amino-1-hydroxy-2-pyrrolidone (HA-966) and 7-chlorokynurenic acid in the modulation of N-methyl-D-aspartate-sensitive glutamate receptors.
Topics: Animals; Dibenzocycloheptenes; Dizocilpine Maleate; Glutamates; Glutamic Acid; Glycine; In Vitro Techniques; Kynurenic Acid; Piperazines; Protein Conformation; Pyrrolidinones; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1989 |
Effects of phencyclidine and other N-methyl-D-aspartate antagonists on the schedule-controlled behavior of rats.
Topics: Animals; Aspartic Acid; Conditioning, Psychological; Dibenzocycloheptenes; Dizocilpine Maleate; Male; N-Methylaspartate; Phenazocine; Phencyclidine; Piperazines; Piperidines; Punishment; Rats; Rats, Inbred Strains; Reinforcement Schedule; Stereoisomerism | 1989 |
Depression of decerebrate rigidity in the rat by antagonists of excitatory amino acids.
Topics: Amino Acids; Animals; Anticonvulsants; Azepines; Blood Pressure; Decerebrate State; Dibenzocycloheptenes; Dizocilpine Maleate; Ketamine; Kynurenic Acid; Male; Muscle Relaxants, Central; Muscle Rigidity; Oxazoles; Oxazolidinones; Piperazines; Rats; Rats, Inbred Strains | 1989 |
Quantitative assessment of neuroprotection against NMDA-induced brain injury.
Topics: Animals; Aspartic Acid; Brain; Brain Diseases; Choline O-Acetyltransferase; Corpus Striatum; Dibenzocycloheptenes; Dizocilpine Maleate; Dose-Response Relationship, Drug; Female; Ketamine; Male; N-Methylaspartate; Piperazines; Rats; Rats, Inbred Strains; Regression Analysis | 1989 |
The effects of N-methyl-D-aspartate antagonists on the development of vestibular compensation in the guinea pig.
Topics: Animals; Anticonvulsants; Aspartic Acid; Dibenzocycloheptenes; Dizocilpine Maleate; Ear, Inner; Guinea Pigs; In Vitro Techniques; N-Methylaspartate; Nystagmus, Physiologic; Piperazines; Vestibule, Labyrinth | 1989 |
Effects of the NMDA receptor/channel antagonists CPP and MK801 on hippocampal field potentials and long-term potentiation in anesthetized rats.
Topics: Action Potentials; Animals; Dibenzocycloheptenes; Dizocilpine Maleate; Electric Stimulation; Hippocampus; Male; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Time Factors | 1988 |
Homocysteic acid as a putative excitatory amino acid neurotransmitter: I. Postsynaptic characteristics at N-methyl-D-aspartate-type receptors on striatal cholinergic interneurons.
Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Amino Acids; Animals; Choline; Corpus Striatum; Dibenzocycloheptenes; Dizocilpine Maleate; Homocysteine; Interneurons; Magnesium; Male; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Stereoisomerism; Tachyphylaxis; Tiletamine | 1988 |
Differential effects of competitive and non-competitive N-methyl-D-aspartate antagonists on glucose use in the limbic system.
Topics: Animals; Deoxy Sugars; Deoxyglucose; Dibenzocycloheptenes; Dizocilpine Maleate; Injections, Intravenous; Limbic System; Male; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1988 |
The pharmacological selectivity of three NMDA antagonists.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Aspartic Acid; Dibenzocycloheptenes; Dizocilpine Maleate; Hexamethonium Compounds; In Vitro Techniques; Motor Neurons; N-Methylaspartate; Norepinephrine; Piperazines; Rats; Serotonin; Synaptic Transmission; Valine | 1988 |
Neuroprotective effects of MK-801 in vivo: selectivity and evidence for delayed degeneration mediated by NMDA receptor activation.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthesia; Animals; Aspartic Acid; Brain; Dibenzocycloheptenes; Dizocilpine Maleate; Ibotenic Acid; Isoflurane; Kainic Acid; Male; N-Methylaspartate; Nerve Degeneration; Piperazines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Time Factors | 1988 |
Both competitive and non-competitive antagonists of N-methyl-D-aspartic acid disrupt brightness discrimination in rats.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Dibenzocycloheptenes; Discrimination, Psychological; Dizocilpine Maleate; Light; Male; N-Methylaspartate; Phencyclidine; Piperazines; Rats; Rats, Inbred F344 | 1988 |
The NMDA antagonists MK801 and CPP disrupt compensation for unilateral labyrinthectomy in the guinea pig.
Topics: Adaptation, Physiological; Afferent Pathways; Animals; Aspartic Acid; Denervation; Dibenzocycloheptenes; Dizocilpine Maleate; Ear, Inner; Guinea Pigs; N-Methylaspartate; Neuronal Plasticity; Nystagmus, Pathologic; Piperazines; Vestibule, Labyrinth | 1988 |
Nicotine-induced protection of cultured cortical neurons against N-methyl-D-aspartate receptor-mediated glutamate cytotoxicity.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Glutamates; Glutamic Acid; Nerve Degeneration; Neurons; Nicotine; Parasympathetic Nervous System; Parasympathomimetics; Piperazines; Rats; Receptors, N-Methyl-D-Aspartate | 1994 |
Modulation of N-methyl-D-aspartate (NMDA) antagonist-induced darting behaviour by the peptidomimetic PAMTA.
Topics: Animals; Behavior, Animal; Cattle; Dizocilpine Maleate; Dopamine; Excitatory Amino Acid Antagonists; In Vitro Techniques; Kinetics; Male; Motor Activity; Piperazines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Tetrazoles | 1995 |
Sensitization to apomorphine-induced rotational behavior in 6-OHDA-lesioned rats: effects of NMDA antagonists on drug response.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Dizocilpine Maleate; Dopamine Agonists; Excitatory Amino Acid Antagonists; Male; N-Methylaspartate; Oxidopamine; Piperazines; Rats; Rats, Sprague-Dawley; Rotation; Stereotyped Behavior; Sympathectomy, Chemical | 1995 |
Phase-shifting mechanisms in the mammalian circadian system: new light on the carbachol paradox.
Topics: Animals; Carbachol; Circadian Rhythm; Cricetinae; Dizocilpine Maleate; Immunologic Techniques; Injections, Intraperitoneal; Injections, Intraventricular; Light; Male; Mesocricetus; Motor Activity; Piperazines; Proto-Oncogene Proteins c-fos; Receptors, N-Methyl-D-Aspartate; Staining and Labeling; Suprachiasmatic Nucleus | 1993 |
The amino-terminus of substance P mimics and MK-801 attenuates the effects of capsaicin on nociception and kainic acid-induced behavior in the mouse.
Topics: Analysis of Variance; Animals; Capsaicin; Dizocilpine Maleate; Haloperidol; Kainic Acid; Male; Mice; Pain; Peptide Fragments; Piperazines; Receptors, N-Methyl-D-Aspartate; Substance P | 1993 |
MK-801 inhibits the effects of capsaicin in the adult mouse by an action involving phencyclidine (PCP) sites not linked to NMDA activity.
Topics: Animals; Behavior, Animal; Capsaicin; Dizocilpine Maleate; Haloperidol; Injections, Spinal; Kainic Acid; Male; Mice; Pain Measurement; Pain Threshold; Peptide Fragments; Piperazines; Receptors, N-Methyl-D-Aspartate; Receptors, Phencyclidine; Substance P | 1993 |
Regulation of sigma activity by the amino-terminus of substance P in the mouse spinal cord: involvement of phencyclidine (PCP) sites not linked to N-methyl-D-aspartate (NMDA) activity.
Topics: Animals; Behavior, Animal; Dizocilpine Maleate; Drug Synergism; Guanidines; Haloperidol; Injections, Spinal; Kainic Acid; Male; Mice; N-Methylaspartate; Peptide Fragments; Piperazines; Receptors, N-Methyl-D-Aspartate; Receptors, Phencyclidine; Receptors, sigma; Spinal Cord; Substance P; Up-Regulation | 1993 |
Seizures during ethanol withdrawal are blocked by focal microinjection of excitant amino acid antagonists into the inferior colliculus and pontine reticular formation.
Topics: Acoustic Stimulation; Alcohol Withdrawal Delirium; Animals; Anticonvulsants; Brain Mapping; Dizocilpine Maleate; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy, Tonic-Clonic; Ethanol; Evoked Potentials; Excitatory Amino Acids; Injections; Male; Piperazines; Pons; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reticular Formation; Seizures | 1994 |
Effects of some excitatory amino acid antagonists on imipenem-induced seizures in DBA/2 mice.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Anticonvulsants; Dizocilpine Maleate; Excitatory Amino Acids; Glutamine; Imipenem; Kynurenic Acid; Mice; Mice, Inbred DBA; Muscimol; Piperazines; Piperidines; Quinoxalines; Seizures | 1995 |
Behavioral studies on FR115427, a novel selective N-methyl-D-aspartate antagonist.
Topics: Animals; Anticonvulsants; Behavior, Animal; Brain; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; In Vitro Techniques; Isoquinolines; Male; Membranes; Mice; Mice, Inbred ICR; Mice, Inbred Strains; Motor Activity; Phencyclidine; Piperazines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Tetrahydroisoquinolines | 1995 |
Modulation of dopamine D1-mediated turning behavior and striatal c-fos expression by the substantia nigra.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Dizocilpine Maleate; Immunohistochemistry; Injections; Male; Neostriatum; Oxidopamine; Piperazines; Proto-Oncogene Proteins c-fos; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; Stereotyped Behavior; Substantia Nigra; Sympathectomy, Chemical | 1995 |
Blockade of transmission at NMDA receptors facilitates the electrical and synthetic activity of ascending serotoninergic neurones.
Topics: 5-Hydroxytryptophan; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Dizocilpine Maleate; Electrophysiology; Hydrazines; Male; Neurons; Piperazines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; Serotonin; Synaptic Transmission | 1994 |
A dopaminergic-glutamatergic basis for the action of amphetamine and cocaine.
Topics: Amphetamine; Animals; Cocaine; Corpus Striatum; Dizocilpine Maleate; Male; Mice; Piperazines; Quinoxalines; Receptors, Dopamine; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Stereotyped Behavior; Sulpiride | 1994 |
Increased N-methyl-D-aspartate (NMDA) activity in the mouse spinal cord following morphine does not mediate opioid withdrawal.
Topics: Analysis of Variance; Animals; Dizocilpine Maleate; Injections, Spinal; Male; Mice; Morphine; N-Methylaspartate; Naloxone; Piperazines; Receptors, N-Methyl-D-Aspartate; Reference Values; Spinal Cord; Stereotyped Behavior; Substance Withdrawal Syndrome | 1994 |
Comparison of the effects of NMDA and AMPA antagonists on the locomotor activity induced by selective D1 and D2 dopamine agonists in reserpine-treated mice.
Topics: 2-Amino-5-phosphonovalerate; 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Dizocilpine Maleate; Dopamine Agonists; Male; Mice; Mice, Inbred Strains; Motor Activity; Phenethylamines; Piperazines; Pyrrolidinones; Quinoxalines; Receptors, AMPA; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate; Reserpine | 1994 |
Contrasting effects of the competitive NMDA antagonist CPP and the non-competitive NMDA antagonist MK 801 on performance of an operant delayed matching to position task in rats.
Topics: Animals; Conditioning, Operant; Discrimination, Psychological; Dizocilpine Maleate; Dose-Response Relationship, Drug; Male; Memory, Short-Term; Mental Recall; Piperazines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 1993 |
NMDA receptors mediate amphetamine-induced upregulation of zif/268 and preprodynorphin mRNA expression in rat striatum.
Topics: Animals; Behavior, Animal; Dextroamphetamine; Dizocilpine Maleate; Dynorphins; Gene Expression; Glutamic Acid; Image Processing, Computer-Assisted; In Situ Hybridization; Male; Neostriatum; Neurons; Piperazines; Protein Precursors; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Up-Regulation | 1994 |
Further evidence for multiple forms of an N-methyl-D-aspartate recognition domain in rat brain using membrane binding techniques.
Topics: 2-Amino-5-phosphonovalerate; 4-Chloromercuribenzenesulfonate; Animals; Brain; Dithionitrobenzoic Acid; Dizocilpine Maleate; Ethylmaleimide; Glutamates; Glutamic Acid; Kinetics; Male; N-Methylaspartate; Piperazines; Rats; Rats, Wistar; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Sulfhydryl Reagents; Synaptic Membranes | 1993 |
Glutamate-dopamine interactions in the production of pilocarpine motor seizures in the mouse.
Topics: 2-Amino-5-phosphonovalerate; 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Dizocilpine Maleate; Dopamine Agents; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Mice; Mice, Inbred Strains; Pilocarpine; Piperazines; Pyrrolidinones; Quinoxalines; Receptors, AMPA; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; Seizures | 1993 |
Nicotine induced c-fos expression in the striatum is mediated mostly by dopamine D1 receptor and is dependent on NMDA stimulation.
Topics: Animals; Benzamides; Benzazepines; Clozapine; Corpus Striatum; Dizocilpine Maleate; Gene Expression Regulation; Genes, fos; Glutamates; Glutamic Acid; Male; Mecamylamine; Nicotine; Nucleus Accumbens; Piperazines; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Receptors, N-Methyl-D-Aspartate; Reward | 1994 |
Competitive NMDA antagonists enhance the catalepsy induced by delta 9-tetrahydrocannabinol in mice.
Topics: 2-Amino-5-phosphonovalerate; 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Amantadine; Amino Acids; Animals; Anticonvulsants; Catalepsy; Dizocilpine Maleate; Dopamine Agonists; Dose-Response Relationship, Drug; Dronabinol; Drug Synergism; Ergolines; Haloperidol; Male; Mice; Mice, Inbred Strains; Motor Activity; Piperazines; Quinpirole; Receptors, N-Methyl-D-Aspartate; Scopolamine | 1994 |
Antinociception induced by 3-((+-)-2-carboxypiperazin-4-yl)-propyl-1- phosphonic acid (CPP), an N-methyl-D-aspartate (NMDA) competitive antagonist, plus 6,7-dinitroquinoxaline-2,3-dione (DNQX), a non-NMDA antagonist, differs from that induced by MK-801 pl
Topics: Animals; Dizocilpine Maleate; Formaldehyde; Injections, Spinal; Male; Mice; Pain; Pain Measurement; Piperazines; Quinoxalines; Receptors, N-Methyl-D-Aspartate | 1994 |
NMDA receptor activation by spermine requires glutamate but not glycine.
Topics: Animals; Dizocilpine Maleate; Glutamates; Glutamic Acid; Glycine; Kynurenic Acid; Male; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spermine | 1993 |
Regionally distinct N-methyl-D-aspartate receptors distinguished by quantitative autoradiography of [3H]MK-801 binding in rat brain.
Topics: Animals; Autoradiography; Brain; Dizocilpine Maleate; Glutamates; Glutamic Acid; Glycine; Kinetics; Kynurenic Acid; Male; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Tissue Distribution; Tritium | 1993 |
Inhibition of [3H]-(+)-MK 801 binding to rat brain sections by CPP and 7-chlorokynurenic acid: an autoradiographic analysis.
Topics: Animals; Autoradiography; Brain; Cerebellum; Dizocilpine Maleate; Glutamates; Glutamic Acid; Glycine; Image Processing, Computer-Assisted; In Vitro Techniques; Kynurenic Acid; Male; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1993 |
MK-801 and phencyclidine act at phencyclidine sites that are not linked to N-methyl-D-aspartate activity to inhibit behavioral sensitization to kainate.
Topics: 2-Amino-5-phosphonovalerate; Animals; Behavior, Animal; Capsaicin; Dizocilpine Maleate; Haloperidol; Kainic Acid; Male; Mice; N-Methylaspartate; Nociceptors; Phencyclidine; Piperazines; Receptors, N-Methyl-D-Aspartate; Receptors, Phencyclidine; Receptors, sigma; Spinal Cord | 1993 |
NMDA receptor antagonists decrease GABA outflow from the septum and increase acetylcholine outflow from the hippocampus: a microdialysis study.
Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Amino Acids; Animals; Dizocilpine Maleate; gamma-Aminobutyric Acid; Hippocampus; Male; Microdialysis; Piperazines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Septal Nuclei; Tetrodotoxin | 1994 |
Behavioral and electrophysiological comparison of ketamine with dizocilpine in the rat.
Topics: Animals; Apomorphine; Behavior, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Globus Pallidus; Ketamine; Male; Motor Activity; Pain Threshold; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 1993 |
NMDA receptors modulate long-term habituation to spatial novelty: dose- and genotype-dependent differential effects of posttrial MK-801 and CPP in rats.
Topics: Animals; Arousal; Attention; Dizocilpine Maleate; Dose-Response Relationship, Drug; Exploratory Behavior; Habituation, Psychophysiologic; Hippocampus; Male; Motor Activity; Orientation; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Social Environment; Species Specificity; Theta Rhythm | 1993 |
Cocaine-induced expression of striatal c-fos in the rat is inhibited by NMDA receptor antagonists.
Topics: Animals; Cocaine; Corpus Striatum; Dizocilpine Maleate; Gene Expression; Genes, fos; Ketamine; Male; Organ Specificity; Piperazines; Prosencephalon; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1993 |
Noncompetitive and competitive NMDA antagonists exert anticonvulsant effects by actions on different sites within the neuronal network for audiogenic seizures.
Topics: Acoustic Stimulation; Animals; Anticonvulsants; Brain; Dizocilpine Maleate; Female; Male; N-Methylaspartate; Nerve Net; Piperazines; Rats; Seizures | 1993 |
MK-801, phencyclidine (PCP), and PCP-like drugs increase burst firing in rat A10 dopamine neurons: comparison to competitive NMDA antagonists.
Topics: Action Potentials; Animals; Dizocilpine Maleate; Dopamine; Dose-Response Relationship, Drug; Illicit Drugs; Male; N-Methylaspartate; Neurons; Phencyclidine; Pipecolic Acids; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Stereotaxic Techniques; Tegmentum Mesencephali; Vibrissae | 1993 |
Anti-exploratory effect of N-methyl-D-aspartate in elevated plus-maze. Involvement of NMDA and CCK receptors.
Topics: Analysis of Variance; Animals; Benzodiazepinones; Cerebral Cortex; Cholecystokinin; Devazepide; Dizocilpine Maleate; Exploratory Behavior; Female; Imipramine; Kinetics; Mice; N-Methylaspartate; Phenylurea Compounds; Piperazines; Proglumide; Radioligand Assay; Receptors, Cholecystokinin; Receptors, N-Methyl-D-Aspartate | 1993 |
Ouabain releases striatal polyamines in vivo independently of N-methyl-D-aspartate receptor activation.
Topics: Animals; Corpus Striatum; Dizocilpine Maleate; Male; N-Methylaspartate; Ouabain; Piperazines; Polyamines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spermidine; Spermine | 1993 |
Manufacture and release characteristics of Elvax polymers containing glutamate receptor antagonists.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Dizocilpine Maleate; Drug Carriers; Drug Implants; Excitatory Amino Acid Antagonists; Ferrets; Molecular Weight; N-Methylaspartate; Piperazines; Polyvinyls; Receptors, Glutamate | 1995 |
N-methyl-D-aspartate transmission modulates GABAB-mediated inhibition of rat hippocampal pyramidal neurons in vitro.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Antagonists; GABA-B Receptor Antagonists; Glutamic Acid; Hippocampus; In Vitro Techniques; Interneurons; N-Methylaspartate; Organophosphorus Compounds; Patch-Clamp Techniques; Piperazines; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 1995 |
Interaction of NMDA and dopamine D2L receptors in human neuroblastoma SH-SY5Y cells.
Topics: Base Sequence; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Humans; Molecular Sequence Data; Neuroblastoma; Piperazines; Polymerase Chain Reaction; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Transfection; Tumor Cells, Cultured; Up-Regulation | 1996 |
Chronic ethanol-mediated up-regulation of the N-methyl-D-aspartate receptor polypeptide subunits in mouse cortical neurons in culture.
Topics: Animals; Binding Sites; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Ethanol; Excitatory Amino Acid Antagonists; Mice; Neurons; Piperazines; Protein Conformation; Receptors, N-Methyl-D-Aspartate; Up-Regulation | 1996 |
Prevention of trauma-induced neurodegeneration in infant rat brain.
Topics: Animals; Brain Injuries; Dendrites; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Piperazines; Quinoxalines; Rats; Rats, Sprague-Dawley; Time Factors; Wounds and Injuries | 1996 |
Investigation of the involvement of the N-methyl-D-aspartate receptor macrocomplex in the development of spermine-induced CNS excitation in vivo.
Topics: Animals; Brain; Cerebral Ventricles; Dizocilpine Maleate; Female; Kynurenic Acid; Mice; Neuroprotective Agents; Piperazines; Piperidines; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Seizures; Spermine; Tremor | 1996 |
Behavioral and neurochemical recovery from partial 6-hydroxydopamine lesions of the substantia nigra is blocked by daily treatment with glutamate receptor antagonists MK-801 and CPP.
Topics: Animals; Behavior, Animal; Dizocilpine Maleate; Drug Administration Schedule; Excitatory Amino Acid Antagonists; Male; Oxidopamine; Piperazines; Rats; Rats, Wistar; Substantia Nigra | 1996 |
A dose-response analysis of the behavioral effects of (+)MK-801 in guinea pig: comparison with CPP.
Topics: Animals; Ataxia; Behavior, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Guinea Pigs; Motor Activity; Piperazines; Postural Balance; Reflex; Stereotyped Behavior | 1996 |
Protection by NMDA receptor antagonists against seizures induced by intracerebral administration of 4-aminopyridine.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; Animals; Anticonvulsants; Convulsants; Dizocilpine Maleate; Electroencephalography; Injections, Intraventricular; Male; Motor Cortex; Neuroprotective Agents; Piperazines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Seizures; Stereotaxic Techniques | 1996 |
Dopamine-N-methyl-D-aspartate interactions in the modulation of locomotor activity and memory consolidation in mice.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Avoidance Learning; Benzazepines; Dizocilpine Maleate; Dopamine Agonists; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Haloperidol; Male; Memory; Mice; Mice, Inbred Strains; Motor Activity; Piperazines; Quinpirole; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate; Sulpiride | 1996 |
Microinjections of phencyclidine (PCP) and related drugs into nucleus accumbens shell potentiate medial forebrain bundle brain stimulation reward.
Topics: Animals; Conditioning, Operant; Dizocilpine Maleate; Dopamine Uptake Inhibitors; Excitatory Amino Acid Antagonists; Male; Medial Forebrain Bundle; Microinjections; Nomifensine; Nucleus Accumbens; Phencyclidine; Piperazines; Rats | 1996 |
N-methyl-D-aspartate antagonist activity of alpha- and beta-sulfallorphans.
Topics: Animals; Anticonvulsants; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Male; Mice; Morphinans; Motor Activity; Piperazines; Receptors, N-Methyl-D-Aspartate; Receptors, Phencyclidine; Receptors, sigma; Structure-Activity Relationship | 1997 |
Use-dependent depression of synaptic NMDA receptor mediated responses by dizocilpine (MK-801).
Topics: Animals; Dizocilpine Maleate; Electric Stimulation; Excitatory Amino Acid Antagonists; Hippocampus; Male; Piperazines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 1997 |
Unique properties of [3H]MK-801 binding in membranes from the rat spinal cord.
Topics: Animals; Binding, Competitive; Cerebral Cortex; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Male; Membranes; Piperazines; Quinolones; Rats; Rats, Sprague-Dawley; Spinal Cord; Tritium | 1997 |
Postnatal lead exposure and MK-801 sensitivity.
Topics: Analysis of Variance; Animals; Animals, Suckling; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Lead Poisoning; Male; N-Methylaspartate; Neuroprotective Agents; Phencyclidine; Piperazines; Rats; Receptors, N-Methyl-D-Aspartate | 1997 |
Selective depression of the spinal polysynaptic reflex by the NMDA receptor antagonists in an isolated spinal cord in vitro.
Topics: Animals; Depression, Chemical; Dizocilpine Maleate; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; In Vitro Techniques; Kynurenic Acid; Male; Piperazines; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reflex; Reflex, Monosynaptic; Serine; Spinal Cord; Spinal Nerve Roots; Strychnine; Valine | 1997 |
Modulation of GAP-43 mRNA by GABA and glutamate in cultured cerebellar granule cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Baclofen; Blotting, Northern; Cells, Cultured; Cerebellum; Cycloleucine; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Agonists; gamma-Aminobutyric Acid; GAP-43 Protein; Gene Expression Regulation, Developmental; Glial Fibrillary Acidic Protein; Glutamic Acid; Immunohistochemistry; In Situ Hybridization; Microtubule-Associated Proteins; Muscimol; N-Methylaspartate; Neurons; Neuroprotective Agents; Piperazines; Rats; Rats, Sprague-Dawley; RNA, Messenger | 1998 |
Direct regulation of acetylcholine release by N-methyl-D-aspartic acid receptors in rat striatum.
Topics: Acetylcholine; Animals; Aziridines; Choline; Choline O-Acetyltransferase; Cholinergic Fibers; Corpus Striatum; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Interneurons; Male; N-Methylaspartate; Neuromuscular Blocking Agents; Piperazines; Radioligand Assay; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Tritium | 1998 |
Galanin stimulates the N-methyl-D-aspartate receptor/nitric oxide/cyclic GMP pathway in vivo in the rat ventral hippocampus.
Topics: Animals; Cyclic GMP; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Galanin; Hippocampus; Locomotion; Male; Microdialysis; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Peptide Fragments; Piperazines; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin | 1998 |
N-methyl-D-aspartate receptor blockade attenuates D1 dopamine receptor modulation of neuronal activity in rat substantia nigra.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Corpus Striatum; Dizocilpine Maleate; Dopamine Agonists; Excitatory Amino Acid Antagonists; Male; Neurons; Oxidopamine; Parkinson Disease, Secondary; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; Reserpine; Stereotaxic Techniques; Substantia Nigra | 1998 |
The role of nitric oxide in striatal acetylcholine release induced by N-methyl-D-aspartate.
Topics: Acetylcholine; Animals; Arginine; Corpus Striatum; Dibutyryl Cyclic GMP; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Male; N-Methylaspartate; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Piperazines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 1998 |
Differences in NMDA receptor antagonist-induced locomotor activity and [3H]MK-801 binding sites in short-sleep and long-sleep mice.
Topics: Animals; Autoradiography; Cerebral Cortex; Dizocilpine Maleate; Dose-Response Relationship, Drug; Ethanol; Excitatory Amino Acid Antagonists; Hippocampus; Male; Mice; Mice, Inbred Strains; Motor Activity; Piperazines; Radioligand Assay; Receptors, N-Methyl-D-Aspartate | 1998 |
Comparison of various N-methyl-D-aspartate receptor antagonists in a model of short-term memory and on overt behaviour.
Topics: Animals; Behavior, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Male; Memory, Short-Term; Motor Activity; Piperazines; Piperidines; Pyrrolidinones; Rats; Receptors, N-Methyl-D-Aspartate; Reinforcement Schedule | 1998 |
Lorazepam attenuates the behavioral effects of dizocilpine.
Topics: Animals; Dizocilpine Maleate; Drug Antagonism; Excitatory Amino Acid Antagonists; GABA Modulators; Lorazepam; Male; Mice; Mice, Inbred ICR; Motor Activity; Pentylenetetrazole; Piperazines; Receptors, N-Methyl-D-Aspartate; Seizures; Stereotyped Behavior | 1999 |
N-Methyl-D-aspartate antagonists and apoptotic cell death triggered by head trauma in developing rat brain.
Topics: Animals; Apoptosis; Brain; Brain Injuries; Caudate Nucleus; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Frontal Lobe; Gyrus Cinguli; In Situ Nick-End Labeling; N-Methylaspartate; Nerve Degeneration; Parietal Lobe; Piperazines; Rats; Rats, Wistar; Thalamus; Time Factors | 1999 |
Protective effect of the N-methyl-D-aspartate receptor antagonists, MK-801 and CPP on cold-induced brain oedema.
Topics: Analysis of Variance; Animals; Blood-Brain Barrier; Body Water; Brain Edema; Cold Temperature; Disease Models, Animal; Dizocilpine Maleate; Evans Blue; Excitatory Amino Acid Antagonists; Male; Neuroprotective Agents; Piperazines; Rats; Rats, Sprague-Dawley; Specific Gravity | 1999 |
Nitric oxide mediates cerebral ischemic tolerance in a neonatal rat model of hypoxic preconditioning.
Topics: Animals; Animals, Newborn; Brain Ischemia; Calcium; Dizocilpine Maleate; Enzyme Inhibitors; Guanidines; Hypoxia; Indazoles; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitroarginine; Oxygen; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1999 |
Interaction of ethanol with excitatory amino acid receptor antagonists in mice.
Topics: Animals; Ataxia; Behavior, Animal; Benzodiazepines; Central Nervous System Depressants; Chlordiazepoxide; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Ethanol; Excitatory Amino Acid Antagonists; Hypnotics and Sedatives; Isoquinolines; Male; Mice; Muscle Relaxation; Pentobarbital; Piperazines; Pregnanolone; Psychomotor Performance; Quinoxalines; Receptors, Glutamate; Tetrazoles | 1999 |
Effect of NMDA antagonists on the activity of glutaminase and aspartate aminotransferase in the developing rat cerebellum.
Topics: 2-Amino-5-phosphonovalerate; Age Factors; Animals; Aspartate Aminotransferases; Body Weight; Cell Differentiation; Cerebellum; Cerebral Cortex; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutaminase; L-Lactate Dehydrogenase; Male; Nerve Fibers; Nerve Tissue Proteins; Neurons; Organ Specificity; Piperazines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 1999 |
Time dependence and role of N-methyl-D-aspartate glutamate receptors in the priming of D2-mediated rotational behavior and striatal Fos expression in 6-hydroxydopamine lesioned rats.
Topics: Animals; Apomorphine; Behavior, Animal; Brain Chemistry; Corpus Striatum; Dizocilpine Maleate; Dopamine Agonists; Excitatory Amino Acid Antagonists; Male; Nerve Degeneration; Oxidopamine; Piperazines; Proto-Oncogene Proteins c-fos; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate; Rotation; Sympatholytics; Time Factors | 1999 |
MK-801 interaction with the 5-HT transporter: a real-time study in brain slices using fast cyclic voltammetry.
Topics: Animals; Carrier Proteins; Dizocilpine Maleate; Dose-Response Relationship, Drug; Electric Stimulation; Fluvoxamine; Half-Life; In Vitro Techniques; Male; Membrane Glycoproteins; Membrane Transport Proteins; Methiothepin; N-Methylaspartate; Nerve Tissue Proteins; Piperazines; Raphe Nuclei; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Serotonin; Serotonin Antagonists; Serotonin Plasma Membrane Transport Proteins; Substantia Nigra | 1999 |
Superoxide dismutase activity and the effect of N-methyl-D-aspartate antagonists on lipid peroxidation in the early phase of cold injury.
Topics: Animals; Brain Concussion; Cold Temperature; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Free Radicals; Hypothermia; Lipid Peroxidation; Male; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Superoxide Dismutase | 1999 |
Selective glutamate receptor antagonists can induce or prevent axonal sprouting in rat hippocampal slice cultures.
Topics: Animals; Axons; Culture Techniques; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; GAP-43 Protein; Glial Fibrillary Acidic Protein; Hippocampus; Nerve Regeneration; Piperazines; Quinoxalines; Rats; Rats, Wistar | 1999 |
Interaction between dopamine and glutamate receptors following treatment with NMDA receptor antagonists.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzamides; Benzazepines; Dizocilpine Maleate; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Female; Oxidopamine; Piperazines; Rats; Rats, Sprague-Dawley; Receptor Cross-Talk; Receptors, AMPA; Receptors, Dopamine; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Tritium | 1999 |
Induction of spontaneous tail-flicks in rats by blockade of transmission at N-methyl-D-aspartate receptors: roles of multiple monoaminergic receptors in relation to the actions of antipsychotic agents.
Topics: 5,7-Dihydroxytryptamine; Adrenergic alpha-Antagonists; Animals; Antipsychotic Agents; Ataxia; Behavior, Animal; Binding Sites; Dizocilpine Maleate; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Male; Mice; Norepinephrine; Nucleus Accumbens; Piperazines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Serotonin; Serotonin Antagonists; Tail; Time Factors | 2000 |
Blockade of NMDA receptors in the nucleus accumbens elicits spontaneous tail-flicks in rats.
Topics: Animals; Behavior, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Indoles; Male; Microinjections; N-Methylaspartate; Nucleus Accumbens; Piperazines; Propionates; Rats; Rats, Wistar; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate | 2000 |
Modulation of [3H]MK-801 binding to NMDA receptors in vivo and in vitro.
Topics: Animals; Binding Sites; Binding, Competitive; Brain; Chromans; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Ketamine; Kinetics; Male; Membranes; Mice; Phencyclidine; Phenols; Piperazines; Piperidines; Pyrrolidinones; Quinolones; Radioligand Assay; Rats; Receptors, N-Methyl-D-Aspartate; Tritium | 2000 |
The HIV-1 coat protein gp120 and some of its fragments potently activate native cerebral NMDA receptors mediating neuropeptide release.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cerebral Cortex; Cholecystokinin; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; HIV Envelope Protein gp120; HIV-1; Indoles; Kynurenic Acid; Male; Maleimides; Neurons; Nitroarginine; Peptide Fragments; Pipecolic Acids; Piperazines; Piperidines; Potassium; Protein Structure, Tertiary; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Somatostatin; Synaptic Transmission; Synaptosomes; Zinc | 2000 |
NMDA glutamate receptor role in the development of context-dependent and independent sensitization of the induction of stereotypy by amphetamine or apomorphine.
Topics: Amphetamine; Animals; Apomorphine; Central Nervous System Stimulants; Dizocilpine Maleate; Dopamine; Environment; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Indazoles; Male; Mice; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Piperazines; Receptors, N-Methyl-D-Aspartate; Stereotyped Behavior | 2000 |
Neuronal death enhanced by N-methyl-D-aspartate antagonists.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Injuries; Cell Death; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Memantine; N-Methylaspartate; Neurons; Neuroprotective Agents; Neurotoxins; Nitro Compounds; Piperazines; Propionates; Quinoxalines; Rats; Rats, Wistar; Wounds and Injuries | 2000 |
Reducing conditions significantly attenuate the neuroprotective efficacy of competitive, but not other NMDA receptor antagonists in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Dithionitrobenzoic Acid; Dithiothreitol; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Hippocampus; Ischemic Attack, Transient; Memantine; N-Methylaspartate; Neurons; Neuroprotective Agents; Organ Culture Techniques; Piperazines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 2000 |
NMDA antagonists block expression of sensitization of amphetamine- and apomorphine-induced stereotypy.
Topics: Amphetamine; Animals; Apomorphine; Arginine; Behavior, Animal; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Indazoles; Male; Mice; Nitric Oxide Synthase; Piperazines; Receptors, N-Methyl-D-Aspartate; Stereotyped Behavior | 2000 |
Inhibition of kainic acid induced expression of interleukin-1 beta and interleukin-1 receptor antagonist mRNA in the rat brain by NMDA receptor antagonists.
Topics: Animals; Behavior, Animal; Dizocilpine Maleate; Epilepsies, Myoclonic; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Gene Expression; In Situ Hybridization; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Kainic Acid; Male; Microglia; Nerve Degeneration; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Sialoglycoproteins | 2000 |
On the interactions between antimuscarinic atropine and NMDA receptor antagonists in anticholinesterase-treated mice.
Topics: Acetylcholinesterase; Animals; Atropine; Brain; Chlorfenvinphos; Cholinesterase Inhibitors; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Antagonism; Excitatory Amino Acid Antagonists; Lethal Dose 50; Male; Methomyl; Mice; Muscarinic Antagonists; Piperazines; Seizures | 2001 |
Increased expression of neuronal Src and tyrosine phosphorylation of NMDA receptors in rat brain after systemic treatment with MK-801.
Topics: Amino Acid Sequence; Animals; Brain; Cloning, Molecular; Dizocilpine Maleate; DNA, Complementary; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Injections, Intraperitoneal; Ketamine; Male; Molecular Sequence Data; Neurons; Phencyclidine; Phosphorylation; Piperazines; Protein Subunits; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Sequence Analysis, DNA; src-Family Kinases; Time Factors; Tyrosine; Up-Regulation | 2001 |
NMDA glutamate receptor stimulation is required for the expression of D2 dopamine mediated responses in apomorphine primed 6-hydroxydopamine lesioned rats.
Topics: Animals; Apomorphine; Behavior, Animal; Brain Chemistry; Denervation; Dizocilpine Maleate; Dopamine Agonists; Excitatory Amino Acid Antagonists; Male; Oxidopamine; Parkinson Disease; Piperazines; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate; Sympatholytics | 2001 |
Role of the NMDA receptor subunit in the expression of the discriminative stimulus effect induced by ketamine.
Topics: Animals; Dextromethorphan; Discrimination Learning; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Guanidines; Ketamine; Ligands; Male; Phencyclidine; Piperazines; Piperidines; Protein Subunits; Rats; Rats, Inbred F344; Receptors, N-Methyl-D-Aspartate; Receptors, sigma | 2001 |
NMDA receptor activation limits the number of synaptic connections during hippocampal development.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Cell Surface Extensions; Cells, Cultured; Dendrites; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; Histocytochemistry; In Vitro Techniques; Ion Channels; Lysine; Microscopy, Confocal; Patch-Clamp Techniques; Piperazines; Pyramidal Cells; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses | 2001 |
Long-lasting synaptic modification in the rat hippocampus resulting from NMDA receptor blockade during development.
Topics: Animals; Behavior, Animal; Cell Differentiation; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Hippocampus; Long-Term Potentiation; Neuronal Plasticity; Neurons; Organ Culture Techniques; Piperazines; Pregnancy; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission | 2002 |
Intrathecal high-dose morphine induces spinally-mediated behavioral responses through NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Binding, Competitive; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Hindlimb; Hyperalgesia; Injections, Spinal; Male; Mice; Mice, Mutant Strains; Morphine; Naloxone; Narcotic Antagonists; Nerve Tissue Proteins; Pain Measurement; Piperazines; Piperidines; Pyrrolidinones; Reaction Time; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid; Spinal Cord; Subarachnoid Space | 2002 |
Cooperation between independent hippocampal synapses is controlled by glutamate uptake.
Topics: Animals; Aspartic Acid; Biological Transport; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; In Vitro Techniques; Patch-Clamp Techniques; Piperazines; Pyramidal Cells; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Synapses | 2002 |
Participation of AMPA- and NMDA-type excitatory amino acid receptors in the spinal reflex transmission, in rat.
Topics: Action Potentials; Animals; Animals, Newborn; Anti-Anxiety Agents; Benzodiazepines; Dizocilpine Maleate; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Antagonists; In Vitro Techniques; Magnesium; Models, Neurological; Piperazines; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Reflex, Monosynaptic; Spinal Cord; Synapses; Time Factors; Valine | 2003 |
Expression of heat shock protein 70 induced by 4-aminopyridine through glutamate-mediated excitotoxic stress in rat hippocampus in vivo.
Topics: 4-Aminopyridine; Animals; Anticonvulsants; Cell Count; Chromatography, High Pressure Liquid; Dizocilpine Maleate; Drug Interactions; Electroencephalography; Epilepsy; Extracellular Space; Functional Laterality; Gene Expression; Glutamic Acid; Hippocampus; HSP70 Heat-Shock Proteins; Immunohistochemistry; Male; Microdialysis; Nerve Degeneration; Neuroprotective Agents; Piperazines; Potassium Channel Blockers; Quinoxalines; Rats; Rats, Wistar; Somatosensory Cortex; Stress, Physiological; Time Factors | 2003 |
A comparison of three NMDA receptor antagonists in the treatment of prolonged status epilepticus.
Topics: Animals; Dizocilpine Maleate; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Antagonists; Hippocampus; Male; Piperazines; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Status Epilepticus | 2004 |
Modulation of striatal dopamine release in vitro by agonists of the glycineB site of NMDA receptors; interaction with antipsychotics.
Topics: Animals; Antipsychotic Agents; Clozapine; Corpus Striatum; Dizocilpine Maleate; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Synergism; Glycine; Haloperidol; Magnesium; Male; N-Methylaspartate; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Salicylamides | 2005 |
NMDA antagonists exert distinct effects in experimental organophosphate or carbamate poisoning in mice.
Topics: Animals; Atropine; Carbamates; Cholinesterase Inhibitors; Dichlorvos; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Therapy, Combination; Lethal Dose 50; Male; Mice; N-Methylaspartate; Piperazines; Seizures | 2007 |
Oxidative stress in methamphetamine-induced self-injurious behavior in mice.
Topics: Animals; Benzamides; Biogenic Amines; Brain Chemistry; Cell Count; Central Nervous System Stimulants; Dizocilpine Maleate; Dopamine; Excitatory Amino Acid Antagonists; Immunohistochemistry; Male; Methamphetamine; Mice; Microinjections; Motor Activity; Neostriatum; Oxidative Stress; Piperazines; Poly(ADP-ribose) Polymerase Inhibitors; Self-Injurious Behavior | 2007 |
Increased expression, but not postsynaptic localisation, of ionotropic glutamate receptors during the late-phase of long-term potentiation in the dentate gyrus in vivo.
Topics: Animals; Dentate Gyrus; Dizocilpine Maleate; Electric Stimulation; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Long-Term Potentiation; Male; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses; Time Factors | 2009 |
HSP70 expression protects against hippocampal neurodegeneration induced by endogenous glutamate in vivo.
Topics: 4-Aminopyridine; Animals; Cell Count; Disease Models, Animal; Dizocilpine Maleate; Electroencephalography; Functional Laterality; Glutamic Acid; Hippocampus; HSP70 Heat-Shock Proteins; Male; Neurodegenerative Diseases; Neuroprotective Agents; Piperazines; Rats; Rats, Wistar; Time Factors | 2008 |
NMDA agonists and antagonists induce renal culture cell toxicity.
Topics: Animals; Apoptosis; Cell Line; Cell Survival; Cells, Cultured; Dizocilpine Maleate; Dogs; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Kidney; L-Lactate Dehydrogenase; Opossums; Piperazines; Receptors, N-Methyl-D-Aspartate | 2008 |
The NMDA antagonist MK-801 disrupts reconsolidation of a cocaine-associated memory for conditioned place preference but not for self-administration in rats.
Topics: Analysis of Variance; Animals; Behavior, Addictive; Cocaine; Conditioning, Operant; Dizocilpine Maleate; Dopamine Uptake Inhibitors; Excitatory Amino Acid Antagonists; Extinction, Psychological; Male; Memory; Piperazines; Rats; Rats, Long-Evans; Rats, Sprague-Dawley; Self Administration | 2008 |
Activation of the NMDA receptor involved in the alleviating after-effect of repeated stimulation of the subthalamic nucleus on motor deficits in hemiparkinsonian rats.
Topics: Animals; Deep Brain Stimulation; Dizocilpine Maleate; Dyskinesias; Excitatory Amino Acid Antagonists; Forelimb; Male; Motor Activity; Neuropsychological Tests; Oxidopamine; Parkinsonian Disorders; Piperazines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Subthalamic Nucleus; Time Factors | 2010 |
Deramciclane improves object recognition in rats: potential role of NMDA receptors.
Topics: Animals; Camphanes; Chickens; Dizocilpine Maleate; Dose-Response Relationship, Drug; Evoked Potentials; Excitatory Amino Acid Antagonists; In Vitro Techniques; Male; Memantine; N-Methylaspartate; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Recognition, Psychology; Retina | 2010 |
NMDA receptor blockade at rest triggers rapid behavioural antidepressant responses.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain-Derived Neurotrophic Factor; Depression; Disease Models, Animal; Dizocilpine Maleate; Elongation Factor 2 Kinase; Gene Expression Regulation; Ketamine; Mice; Mice, Inbred C57BL; Mice, Knockout; Phosphorylation; Piperazines; Protein Biosynthesis; Receptors, N-Methyl-D-Aspartate; Rest; Suicide Prevention; Synapses; Synaptic Transmission; Time Factors | 2011 |