3-(2,4-dimethoxybenzylidene)anabaseine has been researched along with tropisetron in 3 studies
| Studies (3-(2,4-dimethoxybenzylidene)anabaseine) | Trials (3-(2,4-dimethoxybenzylidene)anabaseine) | Recent Studies (post-2010) (3-(2,4-dimethoxybenzylidene)anabaseine) | Studies (tropisetron) | Trials (tropisetron) | Recent Studies (post-2010) (tropisetron) |
|---|---|---|---|---|---|
| 166 | 8 | 81 | 944 | 218 | 150 |
| Protein | Taxonomy | 3-(2,4-dimethoxybenzylidene)anabaseine (IC50) | tropisetron (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | 3.1623 | |
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | 3.1623 | |
| Muscarinic acetylcholine receptor M5 | Homo sapiens (human) | 3.45 | |
| Neuronal acetylcholine receptor subunit beta-4 | Homo sapiens (human) | 1.8 | |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | 0.488 | |
| Neuronal acetylcholine receptor subunit alpha-3 | Homo sapiens (human) | 1.8 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bourne, Y; Conrod, S; Hibbs, RE; Kem, WR; Marchot, P; Shi, J; Sulzenbacher, G; Talley, TT; Taylor, P | 1 |
| Li, Y; Shao, S; Shi, C; Yu, R | 1 |
| Jiang, T; Ma, Q; Tabassum, N; Wu, G; Yu, R | 1 |
3 other study(ies) available for 3-(2,4-dimethoxybenzylidene)anabaseine and tropisetron
| Article | Year |
|---|---|
Structural determinants for interaction of partial agonists with acetylcholine binding protein and neuronal alpha7 nicotinic acetylcholine receptor.
Topics: Acetylcholine; Anabasine; Animals; Aplysia; Benzylidene Compounds; Carrier Proteins; Crystallography, X-Ray; Humans; Hydrogen-Ion Concentration; Indoles; Models, Molecular; Nicotinic Agonists; Protein Binding; Protein Conformation; Pyridines; Tropisetron | 2009 |
Partial activation of α7 nicotinic acetylcholine receptors: insights from molecular dynamics simulations.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Benzylidene Compounds; Binding Sites; Carrier Proteins; Humans; Indoles; Molecular Docking Simulation; Molecular Dynamics Simulation; Nicotinic Agonists; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Pyridines; Receptors, Nicotinic; Static Electricity; Thermodynamics; Tropisetron | 2013 |
Exploring the binding energy profiles of full agonists, partial agonists, and antagonists of the α7 nicotinic acetylcholine receptor.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Anabasine; Benzylidene Compounds; Binding Sites; Bridged Bicyclo Compounds, Heterocyclic; Humans; Indoles; Ligands; Lobeline; Molecular Docking Simulation; Nicotinic Agonists; Nicotinic Antagonists; Protein Binding; Pyridines; Strychnine; Tropisetron; Tubocurarine | 2017 |