3-(2,4-dimethoxybenzylidene)anabaseine has been researched along with epibatidine in 9 studies
| Studies (3-(2,4-dimethoxybenzylidene)anabaseine) | Trials (3-(2,4-dimethoxybenzylidene)anabaseine) | Recent Studies (post-2010) (3-(2,4-dimethoxybenzylidene)anabaseine) | Studies (epibatidine) | Trials (epibatidine) | Recent Studies (post-2010) (epibatidine) |
|---|---|---|---|---|---|
| 166 | 8 | 81 | 70 | 0 | 13 |
| 166 | 8 | 81 | 593 | 0 | 115 |
| Protein | Taxonomy | 3-(2,4-dimethoxybenzylidene)anabaseine (IC50) | epibatidine (IC50) |
|---|---|---|---|
| Acetylcholine receptor subunit alpha | Homo sapiens (human) | 0.16 | |
| Neuronal acetylcholine receptor subunit beta-2 | Homo sapiens (human) | 0.0011 | |
| Acetylcholine receptor subunit beta-like 2 | Drosophila melanogaster (fruit fly) | 0.43 | |
| Neuronal acetylcholine receptor subunit alpha-7 | Homo sapiens (human) | 0.031 | |
| Neuronal acetylcholine receptor subunit alpha-4 | Homo sapiens (human) | 0.0011 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (55.56) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dart, MJ; Holladay, MW; Lynch, JK | 1 |
| Frølund, B; Jensen, AA; Krogsgaard-Larsen, P; Liljefors, T | 1 |
| Anderson, DJ; Arneric, SP; Bannon, AW; Briggs, CA; Brioni, JD; Decker, MW; Donnelly-Roberts, D; Holladay, MW; Sullivan, JP; Williams, M | 1 |
| Briggs, CA; McKenna, DG; Piattoni-Kaplan, M | 1 |
| Arneric, SP; Delbono, O; Gopalakrishnan, M; Messi, ML; Molinari, EJ; Renganathan, M; Sullivan, JP | 1 |
| Gurley, DA; Lanthorn, TH | 1 |
| Margiotta, JF; McIntosh, JM; Nai, Q | 1 |
| Blondel, A; Colas, C; Corringer, PJ; Joseph, D; Malliavin, T; Nilges, M; Taly, A | 1 |
| Jiang, T; Ma, Q; Tabassum, N; Wu, G; Yu, R | 1 |
3 review(s) available for 3-(2,4-dimethoxybenzylidene)anabaseine and epibatidine
| Article | Year |
|---|---|
Neuronal nicotinic acetylcholine receptors as targets for drug discovery.
Topics: Acetylcholine; Animals; Binding Sites; Dopamine; Drug Design; Humans; Molecular Structure; Nervous System; Neurons; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Receptors, Nicotinic; Structure-Activity Relationship | 1997 |
Neuronal nicotinic acetylcholine receptors: structural revelations, target identifications, and therapeutic inspirations.
Topics: Allosteric Regulation; Amino Acid Sequence; Animals; Humans; Ligands; Mice; Mice, Knockout; Models, Molecular; Molecular Sequence Data; Nicotinic Agonists; Nicotinic Antagonists; Protein Conformation; Protein Subunits; Receptors, Nicotinic | 2005 |
Cholinergic channel activators: novel opportunities for the treatment of CNS disorders.
Topics: Animals; Anti-Anxiety Agents; Benzylidene Compounds; Bridged Bicyclo Compounds, Heterocyclic; Central Nervous System Diseases; Cholinergic Antagonists; Humans; Ion Channels; Isoxazoles; Nicotinic Agonists; Parasympathetic Nervous System; Pyridines; Pyrrolidines; Receptors, Cholinergic | 1995 |
6 other study(ies) available for 3-(2,4-dimethoxybenzylidene)anabaseine and epibatidine
| Article | Year |
|---|---|
Human alpha 7 nicotinic acetylcholine receptor responses to novel ligands.
Topics: Anti-Anxiety Agents; Barium; Benzylidene Compounds; Binding, Competitive; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Chloride Channels; Dose-Response Relationship, Drug; Humans; Isoxazoles; Ligands; Membrane Potentials; Nicotinic Agonists; Oocytes; Patch-Clamp Techniques; Pyridines; Pyrrolidines; Receptors, Nicotinic; RNA, Messenger | 1995 |
Up-regulation of human alpha7 nicotinic receptors by chronic treatment with activator and antagonist ligands.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Benzylidene Compounds; Binding Sites; Bridged Bicyclo Compounds, Heterocyclic; Bungarotoxins; Dimethylphenylpiperazinium Iodide; Humans; Insecticides; Iodine Radioisotopes; Kidney; Kinetics; Ligands; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Pyridines; Receptors, Nicotinic; Transfection; Up-Regulation | 1998 |
Nicotinic agonists competitively antagonize serotonin at mouse 5-HT3 receptors expressed in Xenopus oocytes.
Topics: Acetylcholine; Animals; Bacterial Toxins; Benzylidene Compounds; Binding Sites; Binding, Competitive; Bridged Bicyclo Compounds, Heterocyclic; Choline; Cyanobacteria Toxins; Dimethylphenylpiperazinium Iodide; DNA, Complementary; Female; Marine Toxins; Mice; Microcystins; Multigene Family; Nicotine; Nicotinic Agonists; Oocytes; Patch-Clamp Techniques; Pyridines; Receptors, Nicotinic; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Recombinant Fusion Proteins; Serotonin Antagonists; Structure-Activity Relationship; Xenopus laevis | 1998 |
Relating neuronal nicotinic acetylcholine receptor subtypes defined by subunit composition and channel function.
Topics: Animals; Benzylidene Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bungarotoxins; Chick Embryo; Cholinergic Antagonists; Conotoxins; Kinetics; Neurons; Nicotine; Nicotinic Agonists; Protein Subunits; Pyridines; Receptors, Nicotinic | 2003 |
Discrimination of agonists versus antagonists of nicotinic ligands based on docking onto AChBP structures.
Topics: Aconitine; Amino Acid Motifs; Animals; Benzylidene Compounds; Binding Sites; Bridged Bicyclo Compounds, Heterocyclic; Carrier Proteins; Computer Simulation; Imidazoles; Lobeline; Lymnaea; Models, Molecular; Neonicotinoids; Nicotinic Agonists; Nicotinic Antagonists; Nitro Compounds; Protein Binding; Pyridines; Surface Properties | 2011 |
Exploring the binding energy profiles of full agonists, partial agonists, and antagonists of the α7 nicotinic acetylcholine receptor.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Anabasine; Benzylidene Compounds; Binding Sites; Bridged Bicyclo Compounds, Heterocyclic; Humans; Indoles; Ligands; Lobeline; Molecular Docking Simulation; Nicotinic Agonists; Nicotinic Antagonists; Protein Binding; Pyridines; Strychnine; Tropisetron; Tubocurarine | 2017 |