3-(2,4-dimethoxybenzylidene)anabaseine and dimethylphenylpiperazinium iodide

3-(2,4-dimethoxybenzylidene)anabaseine has been researched along with dimethylphenylpiperazinium iodide in 4 studies

Compound Research Comparison

Studies (3-(2,4-dimethoxybenzylidene)anabaseine)	Trials (3-(2,4-dimethoxybenzylidene)anabaseine)	Recent Studies (post-2010) (3-(2,4-dimethoxybenzylidene)anabaseine)	Studies (dimethylphenylpiperazinium iodide)	Trials (dimethylphenylpiperazinium iodide)	Recent Studies (post-2010) (dimethylphenylpiperazinium iodide)
166	8	81	15	0	10
166	8	81	766	1	46

Protein Interaction Comparison

Protein	Taxonomy	3-(2,4-dimethoxybenzylidene)anabaseine (IC50)	dimethylphenylpiperazinium iodide (IC50)
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	Homo sapiens (human)		2.62
DNA dC->dU-editing enzyme APOBEC-3A isoform a	Homo sapiens (human)		1.93

Research

Studies (4)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	3 (75.00)	18.2507
2000's	1 (25.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Dart, MJ; Holladay, MW; Lynch, JK	1
Frølund, B; Jensen, AA; Krogsgaard-Larsen, P; Liljefors, T	1
Arneric, SP; Delbono, O; Gopalakrishnan, M; Messi, ML; Molinari, EJ; Renganathan, M; Sullivan, JP	1
Gurley, DA; Lanthorn, TH	1

Reviews

2 review(s) available for 3-(2,4-dimethoxybenzylidene)anabaseine and dimethylphenylpiperazinium iodide

Article	Year
Neuronal nicotinic acetylcholine receptors as targets for drug discovery. Journal of medicinal chemistry, 1997, Dec-19, Volume: 40, Issue:26 Topics: Acetylcholine; Animals; Binding Sites; Dopamine; Drug Design; Humans; Molecular Structure; Nervous System; Neurons; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Receptors, Nicotinic; Structure-Activity Relationship	1997
Neuronal nicotinic acetylcholine receptors: structural revelations, target identifications, and therapeutic inspirations. Journal of medicinal chemistry, 2005, Jul-28, Volume: 48, Issue:15 Topics: Allosteric Regulation; Amino Acid Sequence; Animals; Humans; Ligands; Mice; Mice, Knockout; Models, Molecular; Molecular Sequence Data; Nicotinic Agonists; Nicotinic Antagonists; Protein Conformation; Protein Subunits; Receptors, Nicotinic	2005

Article

Year

Neuronal nicotinic acetylcholine receptors as targets for drug discovery.

Journal of medicinal chemistry, 1997, Dec-19, Volume: 40, Issue:26

Topics: Acetylcholine; Animals; Binding Sites; Dopamine; Drug Design; Humans; Molecular Structure; Nervous System; Neurons; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Receptors, Nicotinic; Structure-Activity Relationship

1997

Neuronal nicotinic acetylcholine receptors: structural revelations, target identifications, and therapeutic inspirations.

Journal of medicinal chemistry, 2005, Jul-28, Volume: 48, Issue:15

Topics: Allosteric Regulation; Amino Acid Sequence; Animals; Humans; Ligands; Mice; Mice, Knockout; Models, Molecular; Molecular Sequence Data; Nicotinic Agonists; Nicotinic Antagonists; Protein Conformation; Protein Subunits; Receptors, Nicotinic

2005

Other Studies

2 other study(ies) available for 3-(2,4-dimethoxybenzylidene)anabaseine and dimethylphenylpiperazinium iodide

Article	Year
Up-regulation of human alpha7 nicotinic receptors by chronic treatment with activator and antagonist ligands. European journal of pharmacology, 1998, Apr-17, Volume: 347, Issue:1 Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Benzylidene Compounds; Binding Sites; Bridged Bicyclo Compounds, Heterocyclic; Bungarotoxins; Dimethylphenylpiperazinium Iodide; Humans; Insecticides; Iodine Radioisotopes; Kidney; Kinetics; Ligands; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Pyridines; Receptors, Nicotinic; Transfection; Up-Regulation	1998
Nicotinic agonists competitively antagonize serotonin at mouse 5-HT3 receptors expressed in Xenopus oocytes. Neuroscience letters, 1998, May-15, Volume: 247, Issue:2-3 Topics: Acetylcholine; Animals; Bacterial Toxins; Benzylidene Compounds; Binding Sites; Binding, Competitive; Bridged Bicyclo Compounds, Heterocyclic; Choline; Cyanobacteria Toxins; Dimethylphenylpiperazinium Iodide; DNA, Complementary; Female; Marine Toxins; Mice; Microcystins; Multigene Family; Nicotine; Nicotinic Agonists; Oocytes; Patch-Clamp Techniques; Pyridines; Receptors, Nicotinic; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Recombinant Fusion Proteins; Serotonin Antagonists; Structure-Activity Relationship; Xenopus laevis	1998

Article

Year

Up-regulation of human alpha7 nicotinic receptors by chronic treatment with activator and antagonist ligands.

European journal of pharmacology, 1998, Apr-17, Volume: 347, Issue:1

Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Benzylidene Compounds; Binding Sites; Bridged Bicyclo Compounds, Heterocyclic; Bungarotoxins; Dimethylphenylpiperazinium Iodide; Humans; Insecticides; Iodine Radioisotopes; Kidney; Kinetics; Ligands; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Pyridines; Receptors, Nicotinic; Transfection; Up-Regulation

1998

Nicotinic agonists competitively antagonize serotonin at mouse 5-HT3 receptors expressed in Xenopus oocytes.

Neuroscience letters, 1998, May-15, Volume: 247, Issue:2-3

Topics: Acetylcholine; Animals; Bacterial Toxins; Benzylidene Compounds; Binding Sites; Binding, Competitive; Bridged Bicyclo Compounds, Heterocyclic; Choline; Cyanobacteria Toxins; Dimethylphenylpiperazinium Iodide; DNA, Complementary; Female; Marine Toxins; Mice; Microcystins; Multigene Family; Nicotine; Nicotinic Agonists; Oocytes; Patch-Clamp Techniques; Pyridines; Receptors, Nicotinic; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Recombinant Fusion Proteins; Serotonin Antagonists; Structure-Activity Relationship; Xenopus laevis

1998