3-(2,4-dimethoxybenzylidene)anabaseine and cytisine

3-(2,4-dimethoxybenzylidene)anabaseine has been researched along with cytisine in 4 studies

Compound Research Comparison

Studies (3-(2,4-dimethoxybenzylidene)anabaseine)	Trials (3-(2,4-dimethoxybenzylidene)anabaseine)	Recent Studies (post-2010) (3-(2,4-dimethoxybenzylidene)anabaseine)	Studies (cytisine)	Trials (cytisine)	Recent Studies (post-2010) (cytisine)
166	8	81	519	19	178

Protein Interaction Comparison

Protein	Taxonomy	cytisine (IC50)
Neuronal acetylcholine receptor subunit alpha-4	Rattus norvegicus (Norway rat)	0.0692
Neuronal acetylcholine receptor subunit beta-2	Rattus norvegicus (Norway rat)	0.0692
Neuronal acetylcholine receptor subunit beta-2	Homo sapiens (human)	0.05
Neuronal acetylcholine receptor subunit alpha-4	Homo sapiens (human)	0.05

Research

Studies (4)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	3 (75.00)	18.2507
2000's	1 (25.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Dart, MJ; Holladay, MW; Lynch, JK	1
Frølund, B; Jensen, AA; Krogsgaard-Larsen, P; Liljefors, T	1
Akaike, A; Kihara, T; Shimohama, S	1
Anderson, KG; Haworth, SC; Kem, WR; van Haaren, F	1

Reviews

2 review(s) available for 3-(2,4-dimethoxybenzylidene)anabaseine and cytisine

Article	Year
Neuronal nicotinic acetylcholine receptors as targets for drug discovery. Journal of medicinal chemistry, 1997, Dec-19, Volume: 40, Issue:26 Topics: Acetylcholine; Animals; Binding Sites; Dopamine; Drug Design; Humans; Molecular Structure; Nervous System; Neurons; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Receptors, Nicotinic; Structure-Activity Relationship	1997
Neuronal nicotinic acetylcholine receptors: structural revelations, target identifications, and therapeutic inspirations. Journal of medicinal chemistry, 2005, Jul-28, Volume: 48, Issue:15 Topics: Allosteric Regulation; Amino Acid Sequence; Animals; Humans; Ligands; Mice; Mice, Knockout; Models, Molecular; Molecular Sequence Data; Nicotinic Agonists; Nicotinic Antagonists; Protein Conformation; Protein Subunits; Receptors, Nicotinic	2005

Article

Year

Neuronal nicotinic acetylcholine receptors as targets for drug discovery.

Journal of medicinal chemistry, 1997, Dec-19, Volume: 40, Issue:26

Topics: Acetylcholine; Animals; Binding Sites; Dopamine; Drug Design; Humans; Molecular Structure; Nervous System; Neurons; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Receptors, Nicotinic; Structure-Activity Relationship

1997

Neuronal nicotinic acetylcholine receptors: structural revelations, target identifications, and therapeutic inspirations.

Journal of medicinal chemistry, 2005, Jul-28, Volume: 48, Issue:15

Topics: Allosteric Regulation; Amino Acid Sequence; Animals; Humans; Ligands; Mice; Mice, Knockout; Models, Molecular; Molecular Sequence Data; Nicotinic Agonists; Nicotinic Antagonists; Protein Conformation; Protein Subunits; Receptors, Nicotinic

2005

Other Studies

2 other study(ies) available for 3-(2,4-dimethoxybenzylidene)anabaseine and cytisine

Article	Year
Effects of nicotinic receptor agonists on beta-amyloid beta-sheet formation. Japanese journal of pharmacology, 1999, Volume: 79, Issue:3 Topics: Alkaloids; Amyloid beta-Peptides; Azocines; Benzylidene Compounds; Hydrogen-Ion Concentration; Nicotine; Nicotinic Agonists; Protein Structure, Secondary; Pyridines; Quinolizines	1999
GTS-21, a mixed nicotinic receptor agonist/antagonist, does not affect the nicotine cue. Pharmacology, biochemistry, and behavior, 1999, Volume: 64, Issue:2 Topics: Alkaloids; alpha7 Nicotinic Acetylcholine Receptor; Anabasine; Animals; Azocines; Benzylidene Compounds; Cues; Discrimination Learning; Discrimination, Psychological; Generalization, Stimulus; Male; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Pyridines; Quinolizines; Rats; Rats, Long-Evans; Receptors, Nicotinic	1999

Article

Year

Effects of nicotinic receptor agonists on beta-amyloid beta-sheet formation.

Japanese journal of pharmacology, 1999, Volume: 79, Issue:3

Topics: Alkaloids; Amyloid beta-Peptides; Azocines; Benzylidene Compounds; Hydrogen-Ion Concentration; Nicotine; Nicotinic Agonists; Protein Structure, Secondary; Pyridines; Quinolizines

1999

GTS-21, a mixed nicotinic receptor agonist/antagonist, does not affect the nicotine cue.

Pharmacology, biochemistry, and behavior, 1999, Volume: 64, Issue:2

Topics: Alkaloids; alpha7 Nicotinic Acetylcholine Receptor; Anabasine; Animals; Azocines; Benzylidene Compounds; Cues; Discrimination Learning; Discrimination, Psychological; Generalization, Stimulus; Male; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Pyridines; Quinolizines; Rats; Rats, Long-Evans; Receptors, Nicotinic

1999