Page last updated: 2024-09-03

3-(2,4-dimethoxybenzylidene)anabaseine and 3-(4-hydroxy-2-methoxybenzylidene)anabaseine

3-(2,4-dimethoxybenzylidene)anabaseine has been researched along with 3-(4-hydroxy-2-methoxybenzylidene)anabaseine in 5 studies

Compound Research Comparison

Studies
(3-(2,4-dimethoxybenzylidene)anabaseine)
Trials
(3-(2,4-dimethoxybenzylidene)anabaseine)
Recent Studies (post-2010)
(3-(2,4-dimethoxybenzylidene)anabaseine)
Studies
(3-(4-hydroxy-2-methoxybenzylidene)anabaseine)
Trials
(3-(4-hydroxy-2-methoxybenzylidene)anabaseine)
Recent Studies (post-2010) (3-(4-hydroxy-2-methoxybenzylidene)anabaseine)
166881502

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's3 (60.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Huang, X; Papke, RL; Stokes, C; Zhan, CG; Zheng, F1
Bourne, Y; Conrod, S; Hibbs, RE; Kem, WR; Marchot, P; Shi, J; Sulzenbacher, G; Talley, TT; Taylor, P1
Katritzky, AR; Kem, WR; LeFrancois, S; Radzvilovits, M; Slavov, SH; Soti, F; Stoyanova-Slavova, IB1
Caldwell, WS; Chewning, J; Hammond, PS; Hauser, TA; Kombo, DC; Mazurov, A; Tallapragada, K; Talley, TT; Taylor, P; Vasquez-Valdivieso, M; Yohannes, D1
Caldwell, WS; Chewning, J; Hammond, PS; Hauser, TA; Kombo, DC; Mazurov, AA; Speake, J; Tallapragada, K; Yohannes, D1

Other Studies

5 other study(ies) available for 3-(2,4-dimethoxybenzylidene)anabaseine and 3-(4-hydroxy-2-methoxybenzylidene)anabaseine

ArticleYear
Modeling binding modes of alpha7 nicotinic acetylcholine receptor with ligands: the roles of Gln117 and other residues of the receptor in agonist binding.
    Journal of medicinal chemistry, 2008, Oct-23, Volume: 51, Issue:20

    Topics: Computer Simulation; Glutamine; Humans; Ligands; Models, Biological; Models, Molecular; Molecular Structure; Mutation; Nicotinic Agonists; Protein Binding; Receptors, Nicotinic; Structure-Activity Relationship

2008
Structural determinants for interaction of partial agonists with acetylcholine binding protein and neuronal alpha7 nicotinic acetylcholine receptor.
    The EMBO journal, 2009, Oct-07, Volume: 28, Issue:19

    Topics: Acetylcholine; Anabasine; Animals; Aplysia; Benzylidene Compounds; Carrier Proteins; Crystallography, X-Ray; Humans; Hydrogen-Ion Concentration; Indoles; Models, Molecular; Nicotinic Agonists; Protein Binding; Protein Conformation; Pyridines; Tropisetron

2009
A computational study of the binding of 3-(arylidene) anabaseines to two major brain nicotinic acetylcholine receptors and to the acetylcholine binding protein.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:6

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Anabasine; Animals; Aplysia; Brain; Carrier Proteins; Computer Simulation; Models, Molecular; Molecular Conformation; Nicotinic Antagonists; Protein Binding; Quantitative Structure-Activity Relationship; Rats; Receptors, Nicotinic

2010
Docking studies of benzylidene anabaseine interactions with α7 nicotinic acetylcholine receptor (nAChR) and acetylcholine binding proteins (AChBPs): application to the design of related α7 selective ligands.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:11

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Anabasine; Animals; Benzylidene Compounds; Carrier Proteins; Drug Design; Hydrogen Bonding; Ligands; Models, Molecular; Protein Conformation; Rats; Receptors, Nicotinic; Substrate Specificity

2011
Discovery of novel α7 nicotinic acetylcholine receptor ligands via pharmacophoric and docking studies of benzylidene anabaseine analogs.
    Bioorganic & medicinal chemistry letters, 2012, Jan-15, Volume: 22, Issue:2

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Anabasine; Benzylidene Compounds; Crystallography, X-Ray; Dose-Response Relationship, Drug; Drug Discovery; Humans; Hydrophobic and Hydrophilic Interactions; Ligands; Models, Molecular; Molecular Structure; Receptors, Nicotinic; Stereoisomerism; Structure-Activity Relationship

2012