Compounds > 3-(2-(2,4,6-trimethylphenyl)thioethyl)-4-methylsydnone
Page last updated: 2024-09-03

3-(2-(2,4,6-trimethylphenyl)thioethyl)-4-methylsydnone and pyrimethamine

3-(2-(2,4,6-trimethylphenyl)thioethyl)-4-methylsydnone has been researched along with pyrimethamine in 1 studies

Compound Research Comparison

Studies
(3-(2-(2,4,6-trimethylphenyl)thioethyl)-4-methylsydnone)		Trials
(3-(2-(2,4,6-trimethylphenyl)thioethyl)-4-methylsydnone)		Recent Studies (post-2010)
(3-(2-(2,4,6-trimethylphenyl)thioethyl)-4-methylsydnone)		Studies
(pyrimethamine)		Trials
(pyrimethamine)		Recent Studies (post-2010) (pyrimethamine)
11005,0887381,047

Protein Interaction Comparison

ProteinTaxonomy3-(2-(2,4,6-trimethylphenyl)thioethyl)-4-methylsydnone (IC50)pyrimethamine (IC50)
Dihydrofolate reductaseHomo sapiens (human)3.1057
Dihydrofolate reductase Bos taurus (cattle)0.1007
Beta-hexosaminidase subunit alphaHomo sapiens (human)6.8333
Beta-hexosaminidase subunit betaHomo sapiens (human)6.4
Dihydrofolate reductaseEscherichia coli K-124.3
Bifunctional dihydrofolate reductase-thymidylate synthasePlasmodium falciparum K10.0609
Dihydrofolate reductasePneumocystis carinii3.25
Dihydrofolate reductaseCandida albicans5
Low molecular weight phosphotyrosine protein phosphataseHomo sapiens (human)15.615
Dipeptidyl peptidase 4Homo sapiens (human)0.39
Bifunctional dihydrofolate reductase-thymidylate synthaseToxoplasma gondii0.3217
Bifunctional dihydrofolate reductase-thymidylate synthasePlasmodium falciparum 3D72.48
Dihydrofolate reductaseRattus norvegicus (Norway rat)2.0727

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jurima-Romet, M; Kobus, SM; Marks, GS; McNamee, JP1

Other Studies

1 other study(ies) available for 3-(2-(2,4,6-trimethylphenyl)thioethyl)-4-methylsydnone and pyrimethamine

ArticleYear
cDNA-expressed human cytochrome P450 isozymes. Inactivation by porphyrinogenic xenobiotics.
    Drug metabolism and disposition: the biological fate of chemicals, 1997, Volume: 25, Issue:4

    Topics: Allylisopropylacetamide; Cell Line; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; DNA, Complementary; Enzyme Inhibitors; Humans; Isoenzymes; Lymphocytes; Microsomes; Pyrimethamine; Sydnones

1997