3-(1-methyl-1,2,3,6-tetrahydropyrid-4-yl)indole and 5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole

3-(1-methyl-1,2,3,6-tetrahydropyrid-4-yl)indole has been researched along with 5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole in 2 studies

Compound Research Comparison

Studies (3-(1-methyl-1,2,3,6-tetrahydropyrid-4-yl)indole)	Trials (3-(1-methyl-1,2,3,6-tetrahydropyrid-4-yl)indole)	Recent Studies (post-2010) (3-(1-methyl-1,2,3,6-tetrahydropyrid-4-yl)indole)	Studies (5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole)	Trials (5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole)	Recent Studies (post-2010) (5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole)
10	0	0	218	0	12

Protein Interaction Comparison

Protein	Taxonomy	5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole (IC50)
5-hydroxytryptamine receptor 2C	Rattus norvegicus (Norway rat)	5.4
5-hydroxytryptamine receptor 2A	Rattus norvegicus (Norway rat)	5.4
5-hydroxytryptamine receptor 1A	Rattus norvegicus (Norway rat)	0.0107
5-hydroxytryptamine receptor 1D	Homo sapiens (human)	0.039
5-hydroxytryptamine receptor 2C	Homo sapiens (human)	0.295
5-hydroxytryptamine receptor 1B	Rattus norvegicus (Norway rat)	0.004
5-hydroxytryptamine receptor 2B	Rattus norvegicus (Norway rat)	5.4
5-hydroxytryptamine receptor 6	Homo sapiens (human)	0.079

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (100.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Agarwal, A; Dahlgren, T; Herslöf, M; Lambert, G; Li, HB; Nelson, DL; Pearson, PP; Regan, JW; Taylor, EW; Yang, Y	1
Carrupt, PA; Gaillard, P; Schambel, P; Testa, B	1

Other Studies

2 other study(ies) available for 3-(1-methyl-1,2,3,6-tetrahydropyrid-4-yl)indole and 5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole

Article	Year
Three-dimensional quantitative structure-activity relationships of 5-HT receptor binding data for tetrahydropyridinylindole derivatives: a comparison of the Hansch and CoMFA methods. Journal of medicinal chemistry, 1993, Dec-10, Volume: 36, Issue:25 Topics: Animals; Binding Sites; Indoles; Male; Models, Molecular; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Stereoisomerism; Structure-Activity Relationship	1993
Binding of arylpiperazines, (aryloxy)propanolamines, and tetrahydropyridylindoles to the 5-HT1A receptor: contribution of the molecular lipophilicity potential to three-dimensional quantitative structure-affinity relationship models. Journal of medicinal chemistry, 1996, Jan-05, Volume: 39, Issue:1 Topics: Indoles; Ligands; Models, Molecular; Molecular Conformation; Molecular Structure; Piperazines; Propanolamines; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Structure-Activity Relationship; Tetrahydronaphthalenes	1996

Article

Year

Three-dimensional quantitative structure-activity relationships of 5-HT receptor binding data for tetrahydropyridinylindole derivatives: a comparison of the Hansch and CoMFA methods.

Journal of medicinal chemistry, 1993, Dec-10, Volume: 36, Issue:25

Topics: Animals; Binding Sites; Indoles; Male; Models, Molecular; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Stereoisomerism; Structure-Activity Relationship

1993

Binding of arylpiperazines, (aryloxy)propanolamines, and tetrahydropyridylindoles to the 5-HT1A receptor: contribution of the molecular lipophilicity potential to three-dimensional quantitative structure-affinity relationship models.

Journal of medicinal chemistry, 1996, Jan-05, Volume: 39, Issue:1

Topics: Indoles; Ligands; Models, Molecular; Molecular Conformation; Molecular Structure; Piperazines; Propanolamines; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Structure-Activity Relationship; Tetrahydronaphthalenes

1996