2h-1,4-benzoxazine, 3,4-dihydro-2,2-dimethyl-6-nitro-4-(2-pyridinyl)-, n-oxide has been researched along with carbachol in 3 studies
| Studies (2h-1,4-benzoxazine, 3,4-dihydro-2,2-dimethyl-6-nitro-4-(2-pyridinyl)-, n-oxide) | Trials (2h-1,4-benzoxazine, 3,4-dihydro-2,2-dimethyl-6-nitro-4-(2-pyridinyl)-, n-oxide) | Recent Studies (post-2010) (2h-1,4-benzoxazine, 3,4-dihydro-2,2-dimethyl-6-nitro-4-(2-pyridinyl)-, n-oxide) | Studies (carbachol) | Trials (carbachol) | Recent Studies (post-2010) (carbachol) |
|---|---|---|---|---|---|
| 17 | 1 | 0 | 13,918 | 81 | 968 |
| Protein | Taxonomy | 2h-1,4-benzoxazine, 3,4-dihydro-2,2-dimethyl-6-nitro-4-(2-pyridinyl)-, n-oxide (IC50) | carbachol (IC50) |
|---|---|---|---|
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | 0.7849 | |
| Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | 2.0626 | |
| Muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | 3.4134 | |
| Muscarinic acetylcholine receptor M3 | Rattus norvegicus (Norway rat) | 2.9961 | |
| Muscarinic acetylcholine receptor M4 | Rattus norvegicus (Norway rat) | 2.535 | |
| Muscarinic acetylcholine receptor M5 | Rattus norvegicus (Norway rat) | 2.9961 | |
| Muscarinic acetylcholine receptor M2 | Rattus norvegicus (Norway rat) | 2.6638 | |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | 4.849 | |
| Muscarinic acetylcholine receptor M3 | Homo sapiens (human) | 4.99 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Goto, K; Masuda, N; Shibasaki, K; Shirai, Y; Takenaka, T; Uchida, W | 1 |
| Masuda, N; Satoh, N; Shibasaki, K; Shirai, Y; Takenada, T; Uchida, W | 1 |
| Chapple, CR; Chess-Williams, R; Korstanje, C; Martin, SW; Radley, SC | 1 |
3 other study(ies) available for 2h-1,4-benzoxazine, 3,4-dihydro-2,2-dimethyl-6-nitro-4-(2-pyridinyl)-, n-oxide and carbachol
| Article | Year |
|---|---|
Effect of the potassium channel opener YM934 on the contractile response to electrical field stimulation in pig detrusor smooth muscle.
Topics: Adenosine Triphosphate; Animals; Atropine; Benzoxazines; Carbachol; Cholinergic Antagonists; Cyclic N-Oxides; Electric Stimulation; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Oxazines; Parasympatholytics; Parasympathomimetics; Potassium Channels; Swine; Tetrodotoxin; Urinary Bladder | 1995 |
The role of extracellular Ca2+ in carbachol-induced tonic contraction of the pig detrusor smooth muscle.
Topics: Animals; Atropine; Benzoxazines; Calcium; Carbachol; Cyclic N-Oxides; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Oxazines; Potassium Channels; Potassium Chloride; Protein Kinase C; Swine | 1994 |
Relaxant effects of potassium-channel openers on normal and hyper-reflexic detrusor muscle.
Topics: Benzopyrans; Benzoxazines; Carbachol; Cromakalim; Cyclic N-Oxides; Dose-Response Relationship, Drug; Electric Stimulation; Humans; Muscle Relaxation; Oxazines; Parasympatholytics; Potassium Channels; Pyrroles; Reflex, Abnormal; Urinary Bladder | 1997 |