Page last updated: 2024-09-03

27-hydroxycholesterol and alpha-synuclein

27-hydroxycholesterol has been researched along with alpha-synuclein in 6 studies

Compound Research Comparison

Studies
(27-hydroxycholesterol)
Trials
(27-hydroxycholesterol)
Recent Studies (post-2010)
(27-hydroxycholesterol)
Studies
(alpha-synuclein)
Trials
(alpha-synuclein)
Recent Studies (post-2010) (alpha-synuclein)
3451121410,821298,011

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (33.33)29.6817
2010's3 (50.00)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Cheng, D; Garner, B; Kim, WS1
Feist, G; Ghribi, O; Rantham Prabhakara, JP; Schommer, E; Thomasson, S; Thompson, A1
Ghribi, O; Marwarha, G; Rhen, T; Schommer, T1
Ghribi, O; Marwarha, G1
Flick, T; Ghribi, O; Lund, J; Marwarha, G; Schommer, J; Schommer, T1
Cao, X; Chen, L; Dai, L; Meng, L; Wang, G; Wang, J; Yan, M; Zhang, G; Zhang, X; Zhang, Z; Zhou, L1

Reviews

1 review(s) available for 27-hydroxycholesterol and alpha-synuclein

ArticleYear
Does the oxysterol 27-hydroxycholesterol underlie Alzheimer's disease-Parkinson's disease overlap?
    Experimental gerontology, 2015, Volume: 68

    Topics: alpha-Synuclein; Alzheimer Disease; Animals; Brain; Cholesterol, Dietary; Disease Models, Animal; Endoplasmic Reticulum Stress; Homeostasis; Humans; Hydroxycholesterols; Lipid Metabolism; Liver X Receptors; Orphan Nuclear Receptors; Parkinson Disease; Plaque, Amyloid; Rabbits

2015

Other Studies

5 other study(ies) available for 27-hydroxycholesterol and alpha-synuclein

ArticleYear
Regulation of alpha-synuclein expression by liver X receptor ligands in vitro.
    Neuroreport, 2008, Nov-19, Volume: 19, Issue:17

    Topics: alpha-Synuclein; Blotting, Western; Cell Line; Cell Line, Tumor; DNA-Binding Proteins; Gene Expression Regulation; Humans; Hydrocarbons, Fluorinated; Hydroxycholesterols; Ligands; Liver X Receptors; Neuroblastoma; Oligodendroglia; Orphan Nuclear Receptors; Receptors, Cytoplasmic and Nuclear; Response Elements; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfonamides; Up-Regulation

2008
Differential effects of 24-hydroxycholesterol and 27-hydroxycholesterol on tyrosine hydroxylase and alpha-synuclein in human neuroblastoma SH-SY5Y cells.
    Journal of neurochemistry, 2008, Volume: 107, Issue:6

    Topics: alpha-Synuclein; Analysis of Variance; Apoptosis; Cell Line, Tumor; Dopamine; Drug Combinations; Gene Expression Regulation, Neoplastic; Humans; Hydroxycholesterols; In Situ Nick-End Labeling; L-Lactate Dehydrogenase; Neuroblastoma; Norepinephrine; Tetrazolium Salts; Thiazoles; Tyrosine 3-Monooxygenase

2008
The oxysterol 27-hydroxycholesterol regulates α-synuclein and tyrosine hydroxylase expression levels in human neuroblastoma cells through modulation of liver X receptors and estrogen receptors--relevance to Parkinson's disease.
    Journal of neurochemistry, 2011, Volume: 119, Issue:5

    Topics: alpha-Synuclein; Cell Line, Tumor; Disease Progression; Down-Regulation; Estrogen Receptor alpha; Estrogen Receptor beta; Humans; Hydroxycholesterols; Liver X Receptors; Neuroblastoma; Orphan Nuclear Receptors; Parkinson Disease; Signal Transduction; Tyrosine 3-Monooxygenase; Up-Regulation

2011
27-Hydroxycholesterol increases α-synuclein protein levels through proteasomal inhibition in human dopaminergic neurons.
    BMC neuroscience, 2018, 04-03, Volume: 19, Issue:1

    Topics: alpha-Synuclein; Cholesterol; Dopaminergic Neurons; Humans; Hydroxycholesterols; Parkinson Disease; RNA; RNA, Messenger

2018
27-Hydroxycholesterol Drives the Spread of α-Synuclein Pathology in Parkinson's Disease.
    Movement disorders : official journal of the Movement Disorder Society, 2023, Volume: 38, Issue:11

    Topics: alpha-Synuclein; Animals; Cholesterol; Humans; Hydroxycholesterols; Mice; Parkinson Disease

2023