25-hydroxyprotopanaxadiol has been researched along with ginsenosides in 18 studies
| Studies (25-hydroxyprotopanaxadiol) | Trials (25-hydroxyprotopanaxadiol) | Recent Studies (post-2010) (25-hydroxyprotopanaxadiol) | Studies (ginsenosides) | Trials (ginsenosides) | Recent Studies (post-2010) (ginsenosides) |
|---|---|---|---|---|---|
| 21 | 0 | 19 | 4,821 | 61 | 3,179 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (11.11) | 29.6817 |
| 2010's | 13 (72.22) | 24.3611 |
| 2020's | 3 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Hao, M; Hill, DL; Rayburn, ER; Wang, H; Wang, W; Zhang, R; Zhao, Y | 1 |
| Rayburn, ER; Wang, H; Wang, W; Zhang, R; Zhao, Y | 1 |
| Hao, M; Wang, H; Wang, W; Zhang, R; Zhao, Y | 1 |
| Bi, XL; Cao, JQ; Guo, YM; Piao, HR; Wang, P; Yuan, HN; Zhang, SJ; Zhao, YQ | 1 |
| Bi, XL; Piao, HR; Wang, P; Xu, J; Yuan, HN; Zhao, YQ | 1 |
| Bi, X; Jiang, B; Liu, W; Liu, Y; Mou, Y; Wang, P; Xia, X; Zhao, Y | 1 |
| Cai, S; Shi, CH; Suo, H; Tang, X; Yang, L; Zhang, X; Zhao, Y | 1 |
| Bi, X; Fan, D; Hou, Y; Jiang, B; Liu, Y; Mou, T; Wang, P; Xia, X; Zhao, Y | 1 |
| Cao, JQ; Liu, YF; Qu, FZ; Wang, XD; Zhang, XS; Zhao, C; Zhao, YQ | 1 |
| Guo, S; Su, G; Wang, X; Zhang, X; Zhao, C; Zhao, Y | 1 |
| Li, D; Li, Z; Liu, Y; Shen, S; Wang, W; Yu, J; Zhang, R; Zhang, Y | 1 |
| Li, Z; Liu, C; Liu, X; Wang, Z; Yu, J; Zhang, C | 1 |
| Guo, J; Liu, Y; Wang, X; Xu, Z; Zhao, Y | 1 |
| Cao, JQ; Guo, JH; Wang, XD; Zhao, YQ; Zhou, WX | 1 |
| Guo, J; Su, G; Wang, X; Yuan, W; Zhao, Y | 1 |
| De Wang, X; Li, T; Li, Y; Yuan, WH; Zhao, YQ | 1 |
| Cui, X; Li, X; Liu, LP; Piao, HR; Xing, DL; Zhang, QG; Zhao, YQ; Zhou, S | 1 |
| Li, T; Su, G; Zhao, Y | 1 |
18 other study(ies) available for 25-hydroxyprotopanaxadiol and ginsenosides
| Article | Year |
|---|---|
Experimental therapy of prostate cancer with novel natural product anti-cancer ginsenosides.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Transformed; Cell Line, Tumor; Cell Proliferation; Combined Modality Therapy; Fibroblasts; G1 Phase; Ginsenosides; Humans; Male; Mice; Mice, Nude; Prostatic Neoplasms; Xenograft Model Antitumor Assays | 2008 |
Novel ginsenosides 25-OH-PPD and 25-OCH3-PPD as experimental therapy for pancreatic cancer: anticancer activity and mechanisms of action.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Ginsenosides; Humans; Mice; Pancreatic Neoplasms; Proto-Oncogene Proteins c-mdm2; Triterpenes; Xenograft Model Antitumor Assays | 2009 |
Pharmacokinetics and tissue distribution of 25-hydroxyprotopanaxadiol, an anti-cancer compound isolated from Panax ginseng, in athymic mice bearing xenografts of human pancreatic tumors.
Topics: Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; Biological Availability; Chromatography, Liquid; Dose-Response Relationship, Drug; Fruit; Ginsenosides; Humans; Injections, Intravenous; Male; Mice; Mice, Nude; Panax; Pancreatic Neoplasms; Tandem Mass Spectrometry; Tissue Distribution; Xenograft Model Antitumor Assays | 2011 |
Semi-synthesis and anti-tumor evaluation of novel 25-hydroxyprotopanaxadiol derivatives.
Topics: Antineoplastic Agents; Cell Line, Tumor; Chemistry Techniques, Synthetic; Ginsenosides; Humans; Inhibitory Concentration 50 | 2012 |
Synthesis and anti-tumor evaluation of novel 25-hydroxyprotopanaxadiol analogs incorporating natural amino acids.
Topics: Amino Acids; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Ginsenosides; Humans | 2013 |
Anti-tumor activity of three novel derivatives of ginsenoside on colorectal cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Ginsenosides; HCT116 Cells; HT29 Cells; Humans; Molecular Conformation; Panax; Stereoisomerism; Structure-Activity Relationship; Tumor Cells, Cultured | 2014 |
Self-microemulsifying drug-delivery system for improved oral bioavailability of 20(S)-25-methoxyl-dammarane-3β, 12β, 20-triol: preparation and evaluation.
Topics: Administration, Oral; Animals; Biological Availability; Chemistry, Pharmaceutical; Drug Delivery Systems; Drug Stability; Emulsions; Female; Ginsenosides; Male; Nanomedicine; Rats; Rats, Wistar; Sapogenins; Solubility; Surface-Active Agents | 2014 |
Anti-tumor activity of three ginsenoside derivatives in lung cancer is associated with Wnt/β-catenin signaling inhibition.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; beta Catenin; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; G1 Phase Cell Cycle Checkpoints; Ginsenosides; Humans; Lung Neoplasms; Male; Mice; Mice, Nude; Neoplasm Invasiveness; Panax; Wnt Signaling Pathway; Xenograft Model Antitumor Assays | 2014 |
Novel 25-hydroxyprotopanaxadiol derivatives incorporating chloroacetyl chloride and their anti-tumor evaluation.
Topics: Acetates; Antineoplastic Agents; Biological Products; Cell Line, Tumor; Cell Proliferation; Ginsenosides; Humans; Molecular Structure; Neoplasms; Panax; Structure-Activity Relationship | 2014 |
Antitumor activity of ginseng sapogenins, 25-OH-PPD and 25-OCH3-PPD, on gastric cancer cells.
Topics: Antineoplastic Agents; Caspases; Cell Line, Tumor; Cell Proliferation; Cell Survival; DNA Damage; Ginsenosides; Humans; Panax; Sapogenins; Signal Transduction; Stomach Neoplasms | 2016 |
Anticancer 20(R)-dammarane-3β,12β,20,25-tetrol-loaded polymeric micelles: Preparation, quantification and pharmacokinetics.
Topics: Animals; Antineoplastic Agents; Chromatography, Liquid; Ginsenosides; Male; Micelles; Particle Size; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tandem Mass Spectrometry | 2016 |
Inhibitory effects and mechanism of 25-OH-PPD on glomerular mesangial cell proliferation induced by high glucose.
Topics: Animals; Calcium; Cell Line; Cell Proliferation; Cell Size; Cell Survival; Cyclooxygenase 1; Cyclooxygenase 2; Ginsenosides; Glucose; Glutathione Peroxidase; Hypertrophy; Malondialdehyde; Membrane Proteins; Mesangial Cells; Protective Agents; Rats; Superoxide Dismutase | 2016 |
Synthesis of novel 25-hydroxyprotopanaxadiol derivatives by methylation and methoxycarbonylation using dimethyl carbonate as a environment-friendly reagent and their anti-tumor evaluation.
Topics: Antineoplastic Agents; Cell Line, Tumor; Formates; Ginsenosides; HeLa Cells; Humans; Indicators and Reagents; Inhibitory Concentration 50 | 2016 |
Sulfamic and succinic acid derivatives of 25-OH-PPD and their activities to MCF-7, A-549, HCT-116, and BGC-823 cell lines.
Topics: Cell Line, Tumor; Drug Screening Assays, Antitumor; Ginsenosides; Humans; Structure-Activity Relationship; Succinic Acid; Sulfonic Acids | 2017 |
Non-protein amino acid derivatives of 25-methoxylprotopanaxadiol/25-hydroxyprotopanaxadioland their anti-tumour activity evaluation.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Proliferation; Ginsenosides; HCT116 Cells; Humans | 2018 |
2-Pyrazine-PPD, a novel dammarane derivative, showed anticancer activity by reactive oxygen species-mediate apoptosis and endoplasmic reticulum stress in gastric cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Regulatory Proteins; Cell Line, Tumor; Cell Proliferation; Endoplasmic Reticulum Stress; Ginsenosides; Humans; Mitochondria; Oxidative Stress; Reactive Oxygen Species; Signal Transduction; Stomach Neoplasms | 2020 |
The novel ginsenoside AD2 prevents angiotensin II-induced connexin 40 and connexin 43 dysregulation by activating AMP kinase signaling in perfused beating rat atria.
Topics: AMP-Activated Protein Kinases; Angiotensin II; Animals; Connexin 43; Connexins; Down-Regulation; Fibrosis; Gap Junction alpha-5 Protein; Gap Junctions; Ginsenosides; NF-kappa B; Rats; Rats, Sprague-Dawley; Signal Transduction; Transcription Factor AP-1; Transforming Growth Factor beta1; Up-Regulation | 2021 |
Anti-hepatic fibrosis effects of AD-2 affecting the Raf-MEK signaling pathway and inflammatory factors in thioacetamide-induced liver injury.
Topics: Animals; Chemical and Drug Induced Liver Injury, Chronic; Ginsenosides; Inflammation; Liver Cirrhosis; Male; Mice; Mitogen-Activated Protein Kinase Kinases; Panax; raf Kinases; Signal Transduction; Thioacetamide | 2021 |