Page last updated: 2024-09-05

24-norursodeoxycholic acid and lithocholic acid

24-norursodeoxycholic acid has been researched along with lithocholic acid in 2 studies

Compound Research Comparison

Studies
(24-norursodeoxycholic acid)
Trials
(24-norursodeoxycholic acid)
Recent Studies (post-2010)
(24-norursodeoxycholic acid)
Studies
(lithocholic acid)
Trials
(lithocholic acid)
Recent Studies (post-2010) (lithocholic acid)
352271,11124280

Protein Interaction Comparison

ProteinTaxonomy24-norursodeoxycholic acid (IC50)lithocholic acid (IC50)
carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform 1Homo sapiens (human)4.823
60 kDa heat shock protein, mitochondrialHomo sapiens (human)10
Tyrosine-protein phosphatase non-receptor type 2Homo sapiens (human)6.12
Tyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)2.71
10 kDa heat shock protein, mitochondrialHomo sapiens (human)10
Bile acid receptorHomo sapiens (human)0.0183
large T antigenBetapolyomavirus macacae26.1

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Auwerx, J; Gioiello, A; Hofmann, AF; Macchiarulo, A; Pellicciari, R; Saladin, R; Sato, H; Schoonjans, K; Thomas, C; Une, M1
Gilmer, JF; Keaveney, R; Kelleher, D; Long, A; Majer, F; Peta, VK; Sharma, R; Wang, J1

Other Studies

2 other study(ies) available for 24-norursodeoxycholic acid and lithocholic acid

ArticleYear
Novel potent and selective bile acid derivatives as TGR5 agonists: biological screening, structure-activity relationships, and molecular modeling studies.
    Journal of medicinal chemistry, 2008, Mar-27, Volume: 51, Issue:6

    Topics: Animals; Bile Acids and Salts; CHO Cells; Cricetinae; Cricetulus; Drug Design; Drug Evaluation, Preclinical; Hormones; Humans; Ligands; Models, Molecular; Molecular Conformation; Receptors, G-Protein-Coupled; Stereoisomerism; Structure-Activity Relationship

2008
Bile acid toxicity structure-activity relationships: correlations between cell viability and lipophilicity in a panel of new and known bile acids using an oesophageal cell line (HET-1A).
    Bioorganic & medicinal chemistry, 2010, Sep-15, Volume: 18, Issue:18

    Topics: Bile Acids and Salts; Cell Line; Cell Survival; Chromatography, Reverse-Phase; Chromatography, Thin Layer; Esophagus; Humans; Hydrophobic and Hydrophilic Interactions; Structure-Activity Relationship

2010