Page last updated: 2024-09-05

24-norursodeoxycholic acid and chenodeoxycholic acid

24-norursodeoxycholic acid has been researched along with chenodeoxycholic acid in 6 studies

Compound Research Comparison

Studies
(24-norursodeoxycholic acid)
Trials
(24-norursodeoxycholic acid)
Recent Studies (post-2010)
(24-norursodeoxycholic acid)
Studies
(chenodeoxycholic acid)
Trials
(chenodeoxycholic acid)
Recent Studies (post-2010) (chenodeoxycholic acid)
352273,343227742

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (16.67)18.2507
2000's1 (16.67)29.6817
2010's3 (50.00)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Auwerx, J; Gioiello, A; Hofmann, AF; Macchiarulo, A; Pellicciari, R; Saladin, R; Sato, H; Schoonjans, K; Thomas, C; Une, M1
Gilmer, JF; Keaveney, R; Kelleher, D; Long, A; Majer, F; Peta, VK; Sharma, R; Wang, J1
Cipriani, S; D'Amore, C; Di Leva, FS; Festa, C; Fiorucci, S; Limongelli, V; Masullo, D; Monti, MC; Novellino, E; Renga, B; Sepe, V; Zampella, A1
Hagey, LR; Hofmann, AF; Schteingart, CD; Setchell, KD1
Paumgartner, G1
Majee, C; Mishra, R; Sahu, R1

Reviews

1 review(s) available for 24-norursodeoxycholic acid and chenodeoxycholic acid

ArticleYear
An insight into primary biliary cholangitis and its recent advances in treatment: semi-synthetic analogs to combat ursodeoxycholic-acid resistance.
    Expert review of gastroenterology & hepatology, 2020, Volume: 14, Issue:10

    Topics: Animals; Bile Acids and Salts; Chenodeoxycholic Acid; Cholagogues and Choleretics; Cholic Acids; Humans; Liver Cirrhosis, Biliary; Nitrates; Ursodeoxycholic Acid

2020

Other Studies

5 other study(ies) available for 24-norursodeoxycholic acid and chenodeoxycholic acid

ArticleYear
Novel potent and selective bile acid derivatives as TGR5 agonists: biological screening, structure-activity relationships, and molecular modeling studies.
    Journal of medicinal chemistry, 2008, Mar-27, Volume: 51, Issue:6

    Topics: Animals; Bile Acids and Salts; CHO Cells; Cricetinae; Cricetulus; Drug Design; Drug Evaluation, Preclinical; Hormones; Humans; Ligands; Models, Molecular; Molecular Conformation; Receptors, G-Protein-Coupled; Stereoisomerism; Structure-Activity Relationship

2008
Bile acid toxicity structure-activity relationships: correlations between cell viability and lipophilicity in a panel of new and known bile acids using an oesophageal cell line (HET-1A).
    Bioorganic & medicinal chemistry, 2010, Sep-15, Volume: 18, Issue:18

    Topics: Bile Acids and Salts; Cell Line; Cell Survival; Chromatography, Reverse-Phase; Chromatography, Thin Layer; Esophagus; Humans; Hydrophobic and Hydrophilic Interactions; Structure-Activity Relationship

2010
Modification on ursodeoxycholic acid (UDCA) scaffold. discovery of bile acid derivatives as selective agonists of cell-surface G-protein coupled bile acid receptor 1 (GP-BAR1).
    Journal of medicinal chemistry, 2014, Sep-25, Volume: 57, Issue:18

    Topics: Drug Discovery; HEK293 Cells; Hep G2 Cells; Humans; Models, Molecular; Protein Conformation; Receptors, G-Protein-Coupled; Substrate Specificity; Ursodeoxycholic Acid

2014
5 beta-hydroxylation by the liver. Identification of 3,5,7-trihydroxy nor-bile acids as new major biotransformation products of 3,7-dihydroxy nor-bile acids in rodents.
    The Journal of biological chemistry, 1993, May-25, Volume: 268, Issue:15

    Topics: Animals; Bile Acids and Salts; Bile Ducts; Biotransformation; Carbon Radioisotopes; Chenodeoxycholic Acid; Cricetinae; Dogs; Gas Chromatography-Mass Spectrometry; Glucose; Humans; Hydroxylation; In Vitro Techniques; Liver; Magnetic Resonance Spectroscopy; Rabbits; Rats; Species Specificity; Sulfates; Sulfur Radioisotopes; Taurine; Ursodeoxycholic Acid

1993
Pharmacotherapy of cholestatic liver diseases.
    Journal of digestive diseases, 2010, Volume: 11, Issue:3

    Topics: Bile; Chenodeoxycholic Acid; Cholagogues and Choleretics; Cholestasis, Intrahepatic; Chronic Disease; Humans; Liver; Ursodeoxycholic Acid

2010